Abstract：
OBJECTIVE:We aimed to determine the burden of bacillary dysentery in China, its cross-regional variations, trends in morbidity and mortality, the causative bacterial species and antimicrobial resistance patterns. METHODS:We extracted and integrated governmental statistics and relevant medical literature published from 1991 to 2000. Data were also collected from one general hospital each for the six provinces and Jin-an district, Shanghai, representative of six geographical regions and a modern city. FINDINGS:In 2000, 0.8-1.7 million episodes of bacillary dysentery occurred of which 0.5 to 0.7 million were treated at health-care facilities and 0.15-0.20 million patients were hospitalized. The highest morbidity and mortality rates were among the youngest and oldest age groups. Bacillary dysentery peaked during the summer months. The major causative species was Shigella flexneri (86%) and the predominant S. flexneri serotype was 2a (80%). About 74-80% of Shigella isolates remained susceptible to fluorinated quinolones. CONCLUSION:We conclude that while morbidity and mortality due to bacillary dysentery has decreased considerably in China in the past decade due to increasing access to affordable health care and antibiotics, a considerable burden exists among the youngest and oldest age groups and in regions with low economic development. We suggest that while a vaccine would be effective for short- and medium-term control of bacillary dysentery, improved water supply, sanitation, and hygiene are likely to be required for long-term control.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
Wang XY,Tao F,Xiao D,Lee H,Deen J,Gong J,Zhao Y,Zhou W,Li W,Shen B,Song Y,Ma J,Li ZM,Wang Z,Su PY,Chang N,Xu JH,Ouyang PY,von Seidlein L,Xu ZY,Clemens JDdoi
10.2471/blt.05.023853subject
Has Abstractpub_date
2006-07-01 00:00:00pages
561-8issue
7eissn
0042-9686issn
1564-0604pii
S0042-96862006000700018journal_volume
84pub_type
杂志文章abstract：OBJECTIVE:To summarize the existing evidence on the efficacy of artemether and arteether, two artemisinin derivatives, versus quinine for treating cerebral malaria in children. METHODS:We searched the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE and the http://clinicaltrials.gov web site. We also ch...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,评审
doi：10.2471/BLT.08.060327
更新日期：2009-12-01 00:00:00
abstract：:The eradication of smallpox required a unique, fully collaborative international effort on the part of WHO and Member States. In the course of the programme, many lessons were learned in its organization, execution and evaluation which have implications for other international activities. Most important among these wa...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,评审
doi：
更新日期：1987-01-01 00:00:00
abstract：:Intestinal parasitic infections are distributed virtually throughout the world, with high prevalence rates in many regions. Amoebiasis, ascariasis, hookworm infection and trichuriasis are among the ten most common infections in the world. Other parasitic infections such as abdominal angiostrongyliasis, intestinal capi...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1987-01-01 00:00:00
abstract：OBJECTIVE:To assess maternal and neonatal health services in 49 developing countries. METHODS:The services were rated on a scale of 0 to 100 by 10 - 25 experts in each country. The ratings covered emergency and routine services, including family planning, at health centres and district hospitals, access to these servi...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：:The transmissible spongiform encephalopathies (TSE) include bovine spongiform encephalopathy (BSE), which was first described in 1986 in the United Kingdom but has occurred subsequently in several other countries. This Memorandum reviews the existing state of knowledge on all the known spongiform encephalopathies, and...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,评审
doi：
更新日期：1992-01-01 00:00:00
abstract：OBJECTIVE:To compare the effectiveness of oral ivermectin (IV) and two different modalities of topical benzyl benzoate (BB) for treating scabies in a community setting. METHODS:The trial included patients aged 5-65 years with scabies who attended the dermatology department at the Institut d'Hygiène Sociale in Dakar, S...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,随机对照试验
doi：10.2471/blt.08.052308
更新日期：2009-06-01 00:00:00
abstract：:The intrinsic qualities of influenza virus particles may be studied at the biological level from two points of view:(1) The surface structures associated with adsorption to the surface of the susceptible cell and entry into its substance are regarded as essentially somatic in character. Infection is possible only when...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1953-01-01 00:00:00
abstract：:Forecasts of tuberculosis morbidity and mortality are presented for the decade 1990-99. An estimated 88 million new cases of tuberculosis, of which 8 million will be attributable to HIV infection, will occur in the world during the decade; 30 million people are predicted to die of tuberculosis in the same period, incl...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:The author reviews the agricultural use of night-soil, sewage, and sewage sludge from two points of view: the purely agricultural and the sanitary.Knowledge of the chemistry and bacteriology of human faecal matter is still rather scant, and much further work has to be done to find practical ways of digesting night-soi...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1954-01-01 00:00:00
abstract：:The authors first discuss the principle of the Treponema pallidum immobilization (TPI) test, considered both as a qualitative and as a quantitative test, and then various specific aspects of passage of the Nichols strain of treponeme in rabbit testes. A number of important technical details and modifications in the te...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1956-01-01 00:00:00
abstract：:James Chau talks to Ana Lesher Treviño about the challenges faced in communicating about public health. ...
journal_title：Bulletin of the World Health Organization
pub_type： 新闻
doi：10.2471/BLT.19.030819
更新日期：2019-08-01 00:00:00
abstract：:In a case-control study we examined the association of Plasmodium falciparum circumsporozoite antibodies (anti-R32tet32) with subsequent P. falciparum infections. A study population of 140 children living in an endemic area was followed longitudinally for 25 weeks with weekly blood smears for malaria parasites and, on...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
abstract：OBJECTIVE:Rubella vaccine is not included in the immunization schedule in Myanmar. Although surveillance for outbreaks of measles and rubella is conducted nationwide, there is no routine surveillance for congenital rubella syndrome (CRS). Therefore, we organized a study to assess the burden of CRS. METHODS:From 1 Dece...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/blt.05.022814
更新日期：2006-01-01 00:00:00
abstract：:Enzyme immunoassays represent in many cases the preferred procedure for the detection of antigens or corresponding antibodies. However, many of the current procedures are performed suboptimally. This article reviews the available designs, auxiliary recognition systems, production and purification of antibodies, conjug...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,评审
doi：
更新日期：1985-01-01 00:00:00
abstract：:Studies were conducted each month for one year to determine the cercarial-incubation periods of Schistosoma haematobium and Schistosoma bovis in Bulinus truncatus for different months of infection. The snails were kept in outdoor aquaria in order to simulate the natural temperature conditions in the endemic bilharzias...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1966-01-01 00:00:00
abstract：:In a field study conducted in Burma, 54 semi-immune adults suffering from falciparum malaria (mean parasite count, 15 328/mm(3) before treatment) were given a single dose of a fixed combination of 750 mg mefloquine base, 1500 mg sulfadoxine, and 75 mg pyrimethamine (3 tablets of Fansimef). All these patients were clea...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1985-01-01 00:00:00
abstract：:Twenty-six patients suffering from methylmercury poisoning were treated by different therapeutic regimes. Seven received penicillamine or N-acetyl-d-L-penicillamine, 10 were treated with dimercaprol sulfonate and 9, who could not be treated, were given a placebo and were used as controls. Penicillamine, N-acetyl-d-L-p...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：:In the current information age, research synthesis is a particularly useful tool for keeping track of scientific research and making sense of the large volumes of frequently conflicting data derived from primary studies. The Cochrane Collaboration is a global initiative "to help people make well-informed decisions abo...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章,评审
doi：
更新日期：2004-10-01 00:00:00
abstract：:A study was made on the effect of undernutrition on the immunological responses of mice to TAB and BCG vaccines. The mice were fed a diet comprising chapati and germinated grams; one group was fed ad libitum while another was given half the quantity consumed by the first group. The undernourished mice showed a poor im...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：:The third study in a series on the prevalence of non-tuberculosis mycobacteria in Africa is devoted to the investigation of the formamidase activity of 288 cultures of mycobacteria, already typed by a battery of standard tests as pathogenic or atypical (184 strains) and saprophytic (104 strains). Of the latter, 96 (92...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1967-01-01 00:00:00
abstract：:In this paper an analysis of genetic recombinants derived from crosses between two mutant stocks of Vibrio cholerae, strain 162, differing from one another in nutritional requirements and other characters, is presented. It is shown that parent strains possessing a fertility factor (designated as the P factor) function...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1964-01-01 00:00:00
abstract：:There was a dramatic rise in the prevalence of urinary schistosomiasis around Volta Lake within a year of its full impoundment in 1968. Research was undertaken to investigate the epidemiology of the disease in preparation for a control programme. The interplay of three factors-age, sex, and ethnic affiliation-largely ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：INTRODUCTION:In 1996 we conducted a cross-sectional survey to study the epidemiology of smoking among Kuwaiti adults. METHODS:The 4000 participants were selected using a three-stage stratified cluster sampling design. Altogether 3859 participants (1798 males, 2061 females) returned a completed self-administered questi...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:Public and political awareness of emerging infectious diseases is growing, as animal and human health specialists work closer together to avert potential outbreaks. ...
journal_title：Bulletin of the World Health Organization
pub_type： 新闻
doi：10.2471/BLT.11.031211
更新日期：2011-12-01 00:00:00
abstract：:A form of endemic syphilis exists in the Bakwena Reserve of the Bechuanaland Protectorate known by the local name of "dichuchwa". It is similar to bejel, njovera and the endemic syphilis reported elsewhere in the world. The Government of the Protectorate, with the assistance of WHO and UNICEF, began in November 1953 a...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1956-01-01 00:00:00
abstract：:The frequency of radiological examinations in a country is an important indicator of the general scope of such services in that setting. Frequency data obtained from surveys provide health planners with valuable information that can form an objective basis for resource allocation. Also, from the point of view of radia...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:A serological trial of a formolized monovalent Asian influenza vaccine of conventional type, using a range of falling vaccine dilutions, showed a satisfactory antihaemagglutinin response in groups of volunteers vaccinated with relatively low numbers of haemagglutinating units (HU) of the vaccine.Booster injections, gi...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1959-01-01 00:00:00
abstract：OBJECTIVE:To assess the value of self-rated health assessments by examining the association between education and self-rated poor health. METHODS:We used the globally representative population-based sample from the 2002 World Health Survey, composed of 219,713 men and women aged 25 and over in 69 countries, to examine...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：10.2471/BLT.09.067058
更新日期：2010-02-01 00:00:00
abstract：:Several thousand Glossina pallidipes flies were dissected to determine trypanosome infection rates in the Lambwe Valley and to collect information on the hosts of this tsetse. A total of 1 450 (19.3%) flies had mature trypanosome infections but the rate varied between 9.6% and 30.9% in the Lambwe Valley. In the Roo Va...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1972-01-01 00:00:00
abstract：:Water velocity is an important physical factor in the conditioning of streams and canals as habitats for the intermediate snail host of bilharziasis. Ecologists in most of the bilharziasis endemic areas have studied the resistance of these molluscs to the disturbing action of water motion. However, the complex nature ...
journal_title：Bulletin of the World Health Organization
pub_type： 杂志文章
doi：
更新日期：1962-01-01 00:00:00
