Extrapleural pneumonectomy in children.

Abstract:

BACKGROUND/PURPOSE:Extrapleural pneumonectomy (EPP) is an en bloc resection of the pleura, lung, diaphragm, and pericardium. EPP in the pediatric population has not been reported in the literature. We report our experience of using EPP in children to treat a variety of malignancies that involve the pleural surface. METHODS:We performed a retrospective review of all children treated through EPP at our institution. Data were obtained from patient charts and a pediatric database. All patients underwent en bloc resection of the pleura, lung, diaphragm, and pericardium and reconstruction. RESULTS:Four patients underwent EPP from 2000 to 2004 for inflammatory myofibroblastic tumor, spindle cell sarcoma, metastatic neuroblastoma, and malignant mesothelioma. The patients' ages were from 6 to 11 years. The patient with metastatic neuroblastoma had recurrent disease in the left chest 1 year after EPP and died of sepsis; the patient with mesothelioma died of disease extension into the abdomen 1.5 years later. The other 2 patients are free of disease. CONCLUSIONS:EPP can be performed with curative intent in selected pediatric patients with pleural-based malignancies. EPP should be included in the armamentarium of the pediatric thoracic surgeon and evaluated in larger studies.

journal_name

J Pediatr Surg

authors

Flores RM,Su W,Lal D,Rusch VW,La Quaglia MP

doi

10.1016/j.jpedsurg.2006.05.063

subject

Has Abstract

pub_date

2006-10-01 00:00:00

pages

1738-42

issue

10

eissn

0022-3468

issn

1531-5037

pii

S0022-3468(06)00407-6

journal_volume

41

pub_type

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