Abstract：
:Myasthenia gravis is a disorder that most commonly affects young adults but occasionally appears in the elderly. Muscle weakness and easy fatigability, particularly of the ocular muscles, are characteristic. Diagnosis is confirmed by electromyography and the edrophonium (Tensilon) test. The pathology results from inability of acetylcholine to gain access to receptor sites at the neuromuscular junction, possibly because of a blocking antibody produced by the thymus. Initial treatment (in the absence of a thymoma) consists of administration of an anticholinesterase drug. If that is ineffective, thymectomy and/or corticosteroids may be useful.
journal_name
Am Fam Physicianjournal_title
American family physicianauthors
Galdi APsubject
Has Abstractpub_date
1978-06-01 00:00:00pages
95-102issue
6eissn
0002-838Xissn
1532-0650journal_volume
17pub_type
杂志文章abstract：:Relactation means reestablishment of a milk supply and nursing after the cessation of nursing for a variable period. Induced nonpuerperal lactation means establishing a milk supply in a woman who has never been pregnant. When motivation and the breasts have both been carefully examined, preparation includes breast sti...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1976-08-01 00:00:00
abstract：:Most side effects of oral contraceptives can be attributed to an excess or a deficiency of estrogen or progestin. Knowledge of the relative amounts of estrogen and progestin in the available preparations permits a rational adjustment of dosage if side effects occur. With this information, nearly every woman who wants ...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：:An estimated 15% of children in the United States have at least one developmental delay, yet less than one-fifth of those children receive early intervention services before three years of age. Many barriers exist to implementing initial screening and referral, but screening tools can be easily incorporated into the w...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2017-07-01 00:00:00
abstract：:Carbon monoxide poisoning usually results from inhalation of exhaust fumes from motor vehicles, smoke from fires or fumes from faulty heating systems. Carbon monoxide has a high affinity for hemoglobin, with which it forms carboxyhemoglobin. The resulting decrease in both oxygen-carrying capacity and oxygen release ca...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1993-11-01 00:00:00
abstract：:Labor is induced if pregnancy must be completed before the onset of spontaneous labor, usually for reasons of maternal illness, fetal distress or, most commonly, prolonged pregnancy. Although various mechanical methods are available for labor induction, pharmacologic methods are more commonly used. Oxytocin is the sta...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1994-05-01 00:00:00
abstract：:Carpal tunnel syndrome is the most common focal entrapment syndrome. Forceful repetitive activity and vibration may be important workplace risk factors for carpal tunnel syndrome. Although systematic study has suggested that carpal tunnel syndrome is work-related, no clear "dose-response" curve has been found between ...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1994-05-01 00:00:00
abstract：:Despite the widespread use of propoxyphene products as analgesics, there is no profile of a typical abuser of propoxyphene. Propoxyphene is structurally related to methadone and has central nervous system effects similar to those of opioids. The patient with dependence needs professional help in withdrawing from propo...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1985-09-01 00:00:00
abstract：:Endometriosis is a progressive disease affecting 5 to 10 percent of women. It can cause dyspareunia, dysmenorrhea, low back pain and infertility. A definitive diagnosis can be made only by means of laparoscopy. Medical treatment designed to interfere with ovulation generally provides effective pain relief, but the rec...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1999-10-15 00:00:00
abstract：:The U.S. Preventive Services Task Force (USPSTF) has issued recommendations on behavioral counseling to prevent sexually transmitted infections (STIs) and recommendations about screening for individual STIs. Clinicians should obtain a sexual history to assess for behaviors that increase a patient's risk. Community and...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2016-12-01 00:00:00
abstract：:Anaphylaxis is a life-threatening systemic reaction, normally occurring within one to two hours of exposure to an allergen. The incidence of anaphylaxis in the United States is 2.1 per 1,000 person-years. Most anaphylactic reactions occur outside the hospital setting. Urticaria, difficulty breathing, and mucosal swell...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2020-09-15 00:00:00
abstract：:Urine drug screening can enhance workplace safety, monitor medication compliance, and detect drug abuse. Ordering and interpreting these tests requires an understanding of testing modalities, detection times for specific drugs, and common explanations for false-positive and false-negative results. Employment screening...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2010-03-01 00:00:00
abstract：:Stroke can be categorized as ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage. Awakening with or experiencing the abrupt onset of focal neurologic deficits is the hallmark of the diagnosis of ischemic stroke. The most common presenting symptoms of ischemic stroke are speech disturbance and weaknes...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2015-04-15 00:00:00
abstract：:Knee pain is a common presenting complaint with many possible causes. An awareness of certain patterns can help the family physician identify the underlying cause more efficiently. Teenage girls and young women are more likely to have patellar tracking problems such as patellar subluxation and patellofemoral pain synd...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2003-09-01 00:00:00
abstract：:Patients with type 2 diabetes (formerly known as non-insulin-resistant diabetes) have a significantly increased risk of developing cardiovascular disease. Once clinical cardiovascular disease develops, these patients have a poorer prognosis than normoglycemic patients. By inducing endothelial changes, hyperglycemia co...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2000-12-15 00:00:00
abstract：:Poisoning is a common cause of morbidity and mortality in the United States, with several million episodes reported annually. Acute medication poisonings account for nearly one half of all poisonings reported in the United States and should be considered in persons with an acute change in mental status. The initial ap...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2010-02-01 00:00:00
abstract：:Joint and soft tissue injection of the ankle and foot region is a useful diagnostic and therapeutic tool for the family physician. This article reviews the injection procedure for the plantar fascia, ankle joint, tarsal tunnel, interdigital space, and first metatarsophalangeal joint. Indications for plantar fascia inj...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2003-10-01 00:00:00
abstract：:Parkinson's disease is a common neurodegenerative disorder that can cause significant disability and decreased quality of life. The cardinal physical signs of the disease are distal resting tremor, rigidity, bradykinesia, and asymmetric onset. Levodopa is the primary treatment for Parkinson's disease; however, its lon...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2006-12-15 00:00:00
abstract：:Atrial fibrillation is a supraventricular arrhythmia that adversely affects cardiac function and increases the risk of stroke. It is the most common arrhythmia and a major source of morbidity and mortality; its prevalence increases with age. Pulse rate is sensitive, but not specific, for diagnosis, and suspected atria...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2016-09-15 00:00:00
abstract：:The practicality of the office spirometer as an effective, inexpensive diagnostic device is well established. It can be used in a matter of seconds by minimally trained office personnel. Two basic parameters can be quickly and accurately measured: forced vital capacity (FVC), a test of volume indicative of restrictive...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1980-04-01 00:00:00
abstract：:Melanoma is an increasingly common malignancy, and it affects a younger population than most cancers. Risk factors for melanoma include white race, sun sensitivity, family history of melanoma, and melanocytic nevi. Sunburn and intermittent sun exposure appear to increase the risk of developing melanoma. The role of po...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2005-07-15 00:00:00
abstract：:Concussion is the most common head injury in sports. The injury ranges from a simple "ding" to prolonged loss of consciousness with amnesia. Proper grading of the severity of the injury is necessary to establish a protocol for deciding when to allow an athlete to return to his or her sport. This approach to concussion...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1994-09-15 00:00:00
abstract：:After the safety and the tolerable dosage range of a new drug have been determined, it must be evaluated for efficacy and safety in patients having the condition for which the new drug is intended. The nature of certain drugs or diseases of of the patient population desired may suggest a family physician as the best d...
journal_title：American family physician
pub_type： 临床试验,杂志文章
doi：
更新日期：1976-01-01 00:00:00
abstract：:More women, men and children receive medical care each month in the offices of primary care physicians than any other professional setting. There is an urgent need for health policies that encourage further innovation and implementation ...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2001-09-15 00:00:00
abstract：:Peripartum depression affects up to one in seven women and is associated with significant maternal and neonatal morbidity if untreated. A history of depression is the strongest risk factor for developing peripartum depression. The U.S. Preventive Services Task Force recommends screening pregnant and postpartum women f...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2016-05-15 00:00:00
abstract：:Amputated or devascularized digits should be appropriately cooled as quickly as possible. The injured extremity is dressed, splinted and elevated. Careful selection of patients for replantation has yielded satisfying results to both patients and surgeons. Replantation is indicated for a thumb or multiple-digit amputat...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1981-07-01 00:00:00
abstract：:The incidence of skin cancer is increasing by epidemic proportions. Basal cell cancer remains the most common skin neoplasm, and simple excision is generally curative. Squamous cell cancers may be preceded by actinic keratoses-premalignant lesions that are treated with cryotherapy, excision, curettage or topical 5-flu...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2000-07-15 00:00:00
abstract：:Proper suturing technique is essential for obtaining good cosmetic results and avoiding infection, scarring and poor wound healing. Techniques that must be mastered include good eversion of skin edges, avoiding suture marks, maintaining uniform tensile strength along the skin edges and precise approximation of skin ed...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1991-11-01 00:00:00
abstract：:Pressure sore are caused by multiple mechanisms. Preventive management requires relief of pressure, skin care, control of spasms, release of contractures and treatment of infection. Conservative treatment succeeds only when pressure on the ulcer site is relieved. Surgical treatment involves primary, secondary and tert...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1982-02-01 00:00:00
abstract：:External hemorrhoids represent distended vascular tissue in the anal canal distal to the dentate line. Persons with thrombosed external hemorrhoids usually present with pain on standing, sitting or defecating. Acutely tender, thrombosed external hemorrhoids can be surgically removed if encountered within the first 72 ...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2002-04-15 00:00:00
abstract：:In patients with type 2 diabetes mellitus, insulin may be used to augment therapy with oral glycemic medications or as insulin replacement therapy. The American Diabetes Association suggests the use of long-acting (basal) insulin to augment therapy with one or two oral agents or one oral agent plus a glucagon-like pep...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2018-01-01 00:00:00
