Abstract:
:Data based on the prospective study of Job et al. are reanalyzed while initial number of microaneurysms and duration of patient follow-up are controlled. The reported statistical difference in the rate of microaneurysm increase between the single- and the multiple-daily-injection groups may be due to a difference in a subgroup who had a larger number of microaneurysms initially and who were studied for a shorter period of time. No uniform difference was observed in the results of their treatment between the groups given a single injection and those given multiple injections. While this does not invalidate the conclusions of the study, it does point out the need for greater control in conducting future studies.
journal_name
Diabetesjournal_title
Diabetesauthors
Ashikaga T,Borodic G,Sims EAdoi
10.2337/diab.27.5.592subject
Has Abstractpub_date
1978-05-01 00:00:00pages
592-6issue
5eissn
0012-1797issn
1939-327Xjournal_volume
27pub_type
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