Anion gap acidosis with hypoglycemia in acetaminophen toxicity.

Abstract:

:Two case reports of patients with anion gap metabolic lactic acidosis and hypoglycemia are presented. Both patients subsequently died of acute liver failure secondary to acetaminophen hepatotoxicity. The development of type B lactic acidosis with hypoglycemia might have been caused by a deficit in gluconeogenesis secondary to severe hepatic failure and/or a toxic metabolite of acetaminophen. Our findings suggest that acetaminophen toxicity should be considered when lactic acidosis and hypoglycemia are seen.

journal_name

Ann Emerg Med

authors

Zabrodski RM,Schnurr LP

doi

10.1016/s0196-0644(84)80674-5

subject

Has Abstract

pub_date

1984-10-01 00:00:00

pages

956-9

issue

10

eissn

0196-0644

issn

1097-6760

pii

S0196-0644(84)80674-5

journal_volume

13

pub_type

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