Abstract:
OBJECTIVES:We studied whether 5 regulatory agency advisories concerning the possible increased risk of suicidal behavior during antidepressant therapy had an effect on antidepressant prescription trends in Ontario. METHODS:We conducted a population-based, time-series analysis of new monthly antidepressant prescriptions dispensed by the Ontario Drug Benefits program in 3 age groups (younger than 20 years, 20-65 years old, and older than 65 years) over a 7-year period (April 1998 to March 2005). The impact of five advisories about the possible risk of suicide during antidepressant therapy was also analyzed. RESULTS:The number of new prescriptions for selective serotonin reuptake inhibitors as a group did not change after any antidepressant warning in any age group. However, the rate of new paroxetine prescriptions in patients younger than 20 years declined by 54% immediately after the first warning for paroxetine was issued in the United Kingdom in June 2003. That same warning had no effect on new paroxetine prescriptions in the other age categories. CONCLUSION:The warning about paroxetine use in depressed patients younger than 18 years that was issued in the United Kingdom led to a significant decrease in new paroxetine prescriptions for young patients in this country. By contrast, warnings in North America did not influence new antidepressant prescription rates in any patient group.
journal_name
Am J Public Healthjournal_title
American journal of public healthauthors
Kurdyak PA,Juurlink DN,Mamdani MMdoi
10.2105/AJPH.2006.087262subject
Has Abstractpub_date
2007-04-01 00:00:00pages
750-4issue
4eissn
0090-0036issn
1541-0048pii
AJPH.2006.087262journal_volume
97pub_type
杂志文章abstract::Childhood immunization constitutes one of the great success stories of American public health in the 20th century. This essay provides a historical examination of this topic through 4 particularly important examples: diphtheria, pertussis, polio, and measles. Each case study illustrates how new vaccines have posed uni...
journal_title:American journal of public health
pub_type: 历史文章,杂志文章
doi:10.2105/ajph.90.2.199
更新日期:2000-02-01 00:00:00
abstract:OBJECTIVES:After conducting a media campaign focusing on the importance of oral and pharyngeal cancer (OPC) examinations, we assessed mechanisms of behavior change among individuals receiving an OPC examination for the first time. METHODS:We used data from 2 waves of telephone surveys of individuals residing in 36 rur...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2014.302516
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVES:This study investigated whether low concentrations of ambient air pollutants are associated with hospital admissions for ischemic cardiac and cerebrovascular diseases. METHODS:Associations between daily concentrations of sulfur dioxide, nitric oxide, nitrogen dioxide, ozone, and particulates and daily hospi...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.86.9.1273
更新日期:1996-09-01 00:00:00
abstract::Using claims data from 443 employee groups in North Carolina, this study examines the acute care hospital utilization rates of hospital employees and their dependents and compares them to employee groups in non-hospital settings. Results show that hospital employee groups account for 28 per cent more hospital days tha...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.71.9.1021
更新日期:1981-09-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to evaluate the short-term effects of a low-intensity work-site heart disease risk reduction program using a matched pair design with work site as the unit of analysis. METHODS:Twenty-six heterogeneous work sites with between 125 and 750 employees were matched on key organizati...
journal_title:American journal of public health
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2105/ajph.85.2.209
更新日期:1995-02-01 00:00:00
abstract::Use of the Freedom of Information Act can be potentially harmful to the security of research in progress. There is no protection from disclosure of information in grant applications; collected research data can be obtained and disclosed prematurely; and data supporting published research may be acquired and re-analyz...
journal_title:American journal of public health
pub_type: 社论
doi:10.2105/ajph.72.4.335
更新日期:1982-04-01 00:00:00
abstract::Despite recognition of the importance of posttrial access to antiretroviral therapy (ART), the implementation process has not been studied. We examined whether the National Institutes of Health (NIH) guidance document was being implemented in NIH-funded ART trials conducted in developing countries between July 2005 an...
journal_title:American journal of public health
pub_type: 杂志文章,评审
doi:10.2105/AJPH.2008.157982
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVES:We investigated preterm birth (PTB) in relation to maternal occupational exposure and whether effect measures were modified by Hispanic ethnicity and nativity in a population-based sample with high proportion of Hispanics. METHODS:We used a case-control study (n = 2543) nested within a cohort of 58,316 birt...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2013.301457
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVES:We estimated the costs associated with reducing class sizes in kindergarten through grade 3 as well as the effects of small class sizes on selected outcomes such as quality-adjusted life-years and future earnings. METHODS:We used multiple data sets to predict changes in the outcomes assessed according to le...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2006.105478
更新日期:2007-11-01 00:00:00
abstract::We investigated links between police brutality and poor health outcomes among Blacks and identified five intersecting pathways: (1) fatal injuries that increase population-specific mortality rates; (2) adverse physiological responses that increase morbidity; (3) racist public reactions that cause stress; (4) arrests, ...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2017.303691
更新日期:2017-05-01 00:00:00
abstract:OBJECTIVES:We used Bronfenbrenner's ecological systems theory to identify factors that predicted never or sometimes using condoms in a multiethnic cohort of adolescent mothers. METHODS:We interviewed adolescent mothers within 48 hours of delivery and surveyed them 6 and 12 months after delivery (n = 636). We used mult...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2007.131870
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVES:This study tested the hypothesis that tobacco industry campaign contributions influence state legislators' behavior. METHODS:Multivariate simultaneous equations regression was used to analyze data on tobacco industry campaign contributions to state legislators and legislators' tobacco control policy scores ...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.88.6.918
更新日期:1998-06-01 00:00:00
abstract:OBJECTIVES:Data from the Tecumseh Community Health Study were used to estimate excess morbidity owing to influenza, and results were compared with estimates made previously using different methodology for an Institute of Medicine report. METHODS:Study participants from Tecumseh, Michigan, were classified as infected o...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.83.12.1712
更新日期:1993-12-01 00:00:00
abstract:OBJECTIVES:We determined the number of state Medicaid programs adopting initiatives to support preventive dental services provision by nondental health care professionals, their perceived attributes, and implementation barriers. METHODS:We used Qualtrics to conduct a cross-sectional survey in 2008 of Medicaid dental p...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2012.301138
更新日期:2013-08-01 00:00:00
abstract::Workplace violence is becoming increasingly recognized as a serious problem in health care settings. All 628 workers' compensation assaults claimed by minority Los Angeles County health care workers from 1986 through 1990 were abstracted. Population-at-risk data from county personnel computer tapes provided denominato...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.85.7.1011
更新日期:1995-07-01 00:00:00
abstract:OBJECTIVES:This study assessed trends in HIV risk behaviors among injection drug users in New York City from 1990 to 1997. METHODS:Injection drug users were recruited continuously from a large drug detoxification treatment program (N = 2588) and a research storefront located in a high-drug-use area (N = 2701). Informe...
journal_title:American journal of public health
pub_type: 杂志文章,多中心研究
doi:10.2105/ajph.90.7.1112
更新日期:2000-07-01 00:00:00
abstract::The status of mammography screening experience and factors related to utilization were examined in six towns serviced by physician staffs at five hospitals. Data were collected via random digit dial telephone interview of a probability sample of 1184 women, aged 45-75 years. The results showed that 55% of the women re...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.79.11.1499
更新日期:1989-11-01 00:00:00
abstract::The design of a community's built environment influences the physical and mental health of its residents. Because few studies have investigated this relationship, the Centers for Disease Control and Prevention hosted a workshop in May 2002 to help develop a scientific research agenda on these issues. Workshop particip...
journal_title:American journal of public health
pub_type: 共识发展会议,杂志文章,评审
doi:10.2105/ajph.93.9.1500
更新日期:2003-09-01 00:00:00
abstract::The World Bank began operations on June 25, 1946. Although it was established to finance European reconstruction after World War II, the bank today is a considerable force in the health, nutrition, and population (HNP) sector in developing countries. Indeed, it has evolved from having virtually no presence in global h...
journal_title:American journal of public health
pub_type: 历史文章,杂志文章
doi:10.2105/AJPH.2004.042002
更新日期:2005-01-01 00:00:00
abstract::This study examined the prevalence and correlates of unprotected anal intercourse among 758 young African American men who have sex with men. A quarter of the sample reported unprotected anal intercourse in the past 3 months; nonsupportive peer norms and not carrying condoms predicted risky sexual behavior. Effective ...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.94.7.1122
更新日期:2004-07-01 00:00:00
abstract::The emergence in 1988 of ciprofloxacin-resistant methicillin-resistant Staphylococcus aureus (MRSA) in New York City was studied in nine hospitals and eight nursing homes. Of the 43 hospitalized patients studied, 21 were admitted from home, while nine of the 12 nursing home patients were transferred from a hospital. T...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.80.7.810
更新日期:1990-07-01 00:00:00
abstract:OBJECTIVES:We analyzed cervical cancer incidence and mortality data in American Indian and Alaska Native (AI/AN) women compared with women of other races. METHODS:We improved identification of AI/AN race, cervical cancer incidence, and mortality data using Indian Health Service (IHS) patient records; our analyses focu...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2013.301681
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVES:We carried out analyses of smoking in relation to poverty and child care responsibility among women aged 18-54 years residing in the United States. METHODS:With data from the Behavioral Risk Factor Surveillance System, we assessed the interaction effects of poverty and living with young children on maternal...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.94.12.2170
更新日期:2004-12-01 00:00:00
abstract::Objectives. To quantify the number of people in the US who delay medical care annually because of lack of available transportation and to examine the differential prevalence of this barrier for adults across sociodemographic characteristics and patient populations.Methods. We used data from the National Health Intervi...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2020.305579
更新日期:2020-06-01 00:00:00
abstract::Researchers have a responsibility to cause no harm, but research has been a source of distress for indigenous people because of inappropriate methods and practices. The way researchers acquire knowledge in indigenous communities may be as critical for eliminating health disparities as the actual knowledge that is gain...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2006.093641
更新日期:2008-01-01 00:00:00
abstract::This paper compares cases of paralytic poliomyelitis reported to the systems operated by the National Vaccine Injury Compensation Program and the Centers for Disease Control and Prevention (CDC) for reporting of adverse events associated with vaccination. Of the 118 cases of vaccine-associated paralytic poliomyelitis ...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.86.5.734
更新日期:1996-05-01 00:00:00
abstract:OBJECTIVES:Hospitalization of nursing home residents is a growing, poorly defined problem. The purposes of this study were to define rates, patterns, costs, and outcomes of hospitalizations from nursing homes and to consider implications for reducing this problem as part of health care reform. METHODS:Communitywide nu...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.84.10.1615
更新日期:1994-10-01 00:00:00
abstract:OBJECTIVES:I examined genetic influences on smoking among adolescents and differences in the heritability of smoking across states in the United States. METHODS:With data from the National Longitudinal Study of Adolescent Health (participants aged 12-21 years), I used a multilevel twin- and sibling-pair (N = 2060 pair...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2008.134932
更新日期:2009-03-01 00:00:00
abstract::During 33 screening sessions in Denver gay steambaths, 48 of 419 (11.5 per cent) men were found to have asymptomatic gonorrhea and six (1.4 per cent) had early latent syphilis. Questionnaires were administered to 160 men who reported a mean of 7.9 different male sex contacts per month. Female sex contacts were also re...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.67.8.740
更新日期:1977-08-01 00:00:00
abstract:OBJECTIVES:The association between carbonated beverage consumption and bone mineral density was examined in a community-based cohort of older White women. METHODS:One thousand women 44 to 98 years of age had bone mineral density measured at four sites and provided medical and behavioral histories, including type and q...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.87.2.276
更新日期:1997-02-01 00:00:00