Abstract:
:Based upon their migrating properties and effector functions, CD8(+) T cells have been further classified into central memory (T(CM)) and two types of effector memory (T(EM) and T(EMRA)) cells. These memory cells display distinct replicative characteristics. Because apoptosis plays an important role in cellular homeostasis, we have examined the relative sensitivity of naïve (T(N)) and different memory CD8(+) T cells to apoptosis. We show that both T(EM) and T(EMRA) CD8(+) T cells are resistant to apoptosis, whereas T(N) and T(CM) CD8(+) T cells are sensitive to apoptosis.
journal_name
Ann N Y Acad Scijournal_title
Annals of the New York Academy of Sciencesauthors
Gupta S,Gollapudi Sdoi
10.1196/annals.1398.017subject
Has Abstractpub_date
2007-08-01 00:00:00pages
145-50eissn
0077-8923issn
1749-6632pii
1109/1/145journal_volume
1109pub_type
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