The effects of metoclopramide on postoperative ileus. A randomized double-blind study.

Abstract:

:Metoclopramide or placebo was administered postoperatively in a randomized, double-blind fashion to 115 patients undergoing laparotomy. The effect of metoclopramide on postoperative adynamic ileus (PAI) was evaluated. The patients were stratified into two groups: Group A--those with laparotomy without a gastrointestinal anastomosis or ostomy procedure, and group B--those with laparotomy undergoing an anastomosis or ostomy procedure. Metoclopramide reduced nausea and emesis postoperatively. However, the only significant effect on postoperative adynamic ileus was an earlier return to tolerance of solid foods in the patients in Group A.

journal_name

Ann Surg

journal_title

Annals of surgery

authors

Davidson ED,Hersh T,Brinner RA,Barnett SM,Boyle LP

doi

10.1097/00000658-197907000-00006

subject

Has Abstract

pub_date

1979-07-01 00:00:00

pages

27-30

issue

1

eissn

0003-4932

issn

1528-1140

journal_volume

190

pub_type

临床试验,杂志文章,随机对照试验
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    abstract:OBJECTIVE:To examine the financial impact of quality improvement using Medicare payment data. BACKGROUND:Demonstrating a business case for quality improvement--that is, that fewer complications translates into lower costs--is essential to justify investment in quality improvement. Prior research is limited to cross-se...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000001069

    authors: Scally CP,Thumma JR,Birkmeyer JD,Dimick JB

    更新日期:2015-08-01 00:00:00

  • Reconstruction of the pharynx after resection for cancer. A comparison of methods.

    abstract::Repair of the pharynx after extirpation of malignancy may require the introduction of independently vascularized tissue either at the time of resection (primary reconstruction) or later for undesirable sequelae, such as fistula or stenosis. A ten-year retrospective study compares two methods of pharyngeal reconstructi...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198905000-00007

    authors: Coleman JJ 3rd

    更新日期:1989-05-01 00:00:00

  • Neutrophils dysfunction during the course of intra-abdominal infection.

    abstract::Twenty-four patients with intra-peritoneal infections were studied sequentially to evaluate neutrophil chemotaxis, spontaneous migration, and chemiluminescence. In six patients, infection was due to spontaneous disease processes and 18 others, infection was a sequel of intra-abdominal operation. In the patients studie...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198107000-00003

    authors: Solomkin JS,Bauman MP,Nelson RD,Simmons RL

    更新日期:1981-07-01 00:00:00

  • Totally laparoscopic Roux-en-Y duct-to-mucosa pancreaticojejunostomy after middle pancreatectomy: a consecutive nine-case series at a single institution.

    abstract:OBJECTIVE:To present the results of a series of laparoscopic middle pancreatectomies with roux-en-Y duct-to-mucosa pancreaticojejunostomy. SUMMARY OF BACKGROUND DATA:Middle pancreatectomy makes it possible to preserve pancreatic parenchyma in the resection of lesions that traditionally have been treated by distal sple...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e3181724e4a

    authors: Rotellar F,Pardo F,Montiel C,Benito A,Regueira FM,Poveda I,Martí-Cruchaga P,Cienfuegos JA

    更新日期:2008-06-01 00:00:00

  • Effect of intravenous hyperalimentation on established delayed hypersensitivity in the cancer patient.

    abstract::Forty-seven cancer patients were selected for study based on their candidacy for hyperalimentation. Each patient received selected skin test antigens intradermally in the forearm prior to the initiation of hyperalimentation, and at 7-day intervals throughout treatment with either chemotherapy, radiation therapy or sur...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197607000-00010

    authors: Copeland EM,Fadyen BV Jr,Dudrick SJ

    更新日期:1976-07-01 00:00:00

  • Altered gene transcription after burn injury results in depressed T-lymphocyte activation.

    abstract:OBJECTIVE:Patients with major burns and an animal model of burn injury were studied to determine the mechanism of depressed interleukin-2 (IL-2) production after thermal injury and to determine the effect of such injury on IL-2 receptor (IL-2R) expression and function. SUMMARY BACKGROUND DATA:Major burn injury is know...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199409000-00010

    authors: Horgan AF,Mendez MV,O'Riordain DS,Holzheimer RG,Mannick JA,Rodrick ML

    更新日期:1994-09-01 00:00:00

  • Management Considerations for the Surgical Treatment of Colorectal Cancer During the Global Covid-19 Pandemic.

    abstract:OBJECTIVE:The COVID-19 pandemic requires to conscientiously weigh "timely surgical intervention" for colorectal cancer against efforts to conserve hospital resources and protect patients and health care providers. SUMMARY BACKGROUND DATA:Professional societies provided ad-hoc guidance at the outset of the COVID-19 pan...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000004029

    authors: O'Leary MP,Choong KC,Thornblade LW,Fakih MG,Fong Y,Kaiser AM

    更新日期:2020-08-01 00:00:00

  • Should perioperative supplemental oxygen be routinely recommended for surgery patients? A Bayesian meta-analysis.

    abstract:OBJECTIVE:The purpose of this study is to use updated data and Bayesian methods to evaluate the effectiveness of hyperoxia to reduce surgical site infections (SSIs) and/or mortality in both colorectal and all surgery patients. Because few trials assessed potential harms of hyperoxia, hazards were not included. BACKGRO...

    journal_title:Annals of surgery

    pub_type: 杂志文章,meta分析

    doi:10.1097/SLA.0b013e31826cc8da

    authors: Kao LS,Millas SG,Pedroza C,Tyson JE,Lally KP

    更新日期:2012-12-01 00:00:00

  • Repeat hepatic surgery for colorectal cancer metastasis to the liver.

    abstract:OBJECTIVE:The authors addressed whether a repeat hepatic operation is warranted in patients with recurrent isolated hepatic metastases. Are the results as good after second operation as after first hepatic operation? SUMMARY BACKGROUND DATA:Five-year survival after initial hepatic operation for colorectal metastases i...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199606000-00015

    authors: Pinson CW,Wright JK,Chapman WC,Garrard CL,Blair TK,Sawyers JL

    更新日期:1996-06-01 00:00:00

  • The HYSLAR trial: a prospective randomized controlled trial of the use of a restrictive fluid regimen with 3% hypertonic saline versus lactated Ringers in patients undergoing pancreaticoduodenectomy.

    abstract:OBJECTIVE:This study was designed to determine whether the volume and type of fluid administered for pancreaticoduodenectomy impacts postoperative outcomes. BACKGROUND:Three percent hypertonic saline (HYS) has been suggested as a means of reducing the volume of fluid required to sustain tissue perfusion in the periope...

    journal_title:Annals of surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/SLA.0000000000000872

    authors: Lavu H,Sell NM,Carter TI,Winter JM,Maguire DP,Gratch DM,Berman RA,Feil MG,Grunwald Z,Leiby BE,Pequignot EC,Rosato EL,Yeo CJ

    更新日期:2014-09-01 00:00:00

  • Proximal splenorenal shunts for extrahepatic portal venous obstruction in children.

    abstract:OBJECTIVE:The results of proximal splenorenal shunts done in children with extrahepatic portal venous obstruction were evaluated. SUMMARY BACKGROUND DATA:Extrahepatic portal venous obstruction, a common cause of portal hypertension in children in India, is being treated increasingly by endoscopic sclerotherapy instead...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199402000-00011

    authors: Prasad AS,Gupta S,Kohli V,Pande GK,Sahni P,Nundy S

    更新日期:1994-02-01 00:00:00

  • Combination anti-CD2 and anti-CD3 monoclonal antibodies induce tolerance while altering interleukin-2, interleukin-4, tumor necrosis factor, and transforming growth factor-beta production.

    abstract:OBJECTIVE:These studies were designed to elucidate the mechanism by which signals delivered by anti-CD2 monoclonal antibody (MoAb) interfere with activational signals delivered by anti-CD3 MoAb and induce long-term graft survival and tolerance. SUMMARY BACKGROUND DATA:Anti-CD2 or anti-CD3 MoAb can prolong allograft su...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199310000-00009

    authors: Chavin KD,Qin L,Lin J,Woodward JE,Baliga P,Bromberg JS

    更新日期:1993-10-01 00:00:00

  • Going the Extra Mile: Improved Survival for Pancreatic Cancer Patients Traveling to High-volume Centers.

    abstract:OBJECTIVE:This study compares outcomes following pancreaticoduodenectomy (PD) for patients treated at local, low-volume centers and those traveling to high-volume centers. BACKGROUND:Although outcomes for PD are superior at high-volume institutions, not all patients live in proximity to major medical centers. Theoreti...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000001924

    authors: Lidsky ME,Sun Z,Nussbaum DP,Adam MA,Speicher PJ,Blazer DG 3rd

    更新日期:2017-08-01 00:00:00

  • Gastrointestinal hemorrhage from adhesion-related mesenteric varices.

    abstract::As a result of this retrospective analysis of hemorrhage from a porta-systemic venous shunt occurring within the small intestine, we believe that the early diagnosis of the syndrome is strongly suggested by the presence of varices in unusual locations demonstrated by the venous phase of mesenteric arteriography. In al...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197601000-00005

    authors: Moncure AC,Waltman AC,Vandersalm TJ,Linton RR,Levine FH,Abbott WM

    更新日期:1976-01-01 00:00:00

  • Impact of statistical approaches for handling missing data on trauma center quality.

    abstract:OBJECTIVE:To determine whether imputed data can be used to produce unbiased hospital quality measures. BACKGROUND:Different methods for handling missing data may influence which hospitals are designated as quality outliers. METHODS:Monte-Carlo simulation study based on 63,020 patients with no missing data in 68 hospi...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e31818e544b

    authors: Glance LG,Osler TM,Mukamel DB,Meredith W,Dick AW

    更新日期:2009-01-01 00:00:00

  • Gastrointestinal myoelectric and clinical patterns of recovery after laparotomy.

    abstract::The objective of this study was to define the patterns of myoelectric activity that occur throughout the gastrointestinal tract during normal recovery from laparotomy. Electrodes were placed on the stomach, jejunum, and transverse colon of 44 patients undergoing laparotomy. Basal electric rhythms in all areas showed n...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-199006000-00018

    authors: Waldhausen JH,Shaffrey ME,Skenderis BS 2nd,Jones RS,Schirmer BD

    更新日期:1990-06-01 00:00:00

  • Accuracy of gadofosveset-enhanced MRI for nodal staging and restaging in rectal cancer.

    abstract:OBJECTIVE:To prospectively assess the accuracy of gadofosveset-enhanced magnetic resonance imaging (MRI) for nodal staging and restaging in rectal cancer. BACKGROUND:Accurate preoperative assessment of nodal disease in rectal cancer impacts treatment management. Staging with modern imaging techniques (computed tomogra...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e31820b01f1

    authors: Lambregts DM,Beets GL,Maas M,Kessels AG,Bakers FC,Cappendijk VC,Engelen SM,Lahaye MJ,de Bruïne AP,Lammering G,Leiner T,Verwoerd JL,Wildberger JE,Beets-Tan RG

    更新日期:2011-03-01 00:00:00

  • Remission of type 2 diabetes after Roux-en-Y gastric bypass or sleeve gastrectomy is associated with a distinct glycemic profile.

    abstract:BACKGROUND:Roux-en-Y gastric bypass (RYGBP) and sleeve gastrectomy (SG) have been associated with a high remission rate of type 2 diabetes mellitus (T2DM). However, whether such remission is associated with full restoration of postprandial glucose profile and/or the potentially nonrestored glycemic profile is associate...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000000586

    authors: Jiménez A,Ceriello A,Casamitjana R,Flores L,Viaplana-Masclans J,Vidal J

    更新日期:2015-02-01 00:00:00

  • Gastrin release by ethanol in man and in dogs.

    abstract::In man, oral or intravenous administration of ethanol caused a small but definite increase in peripheral serum gastrin concentration (measured by radioimmunoassay). In dogs, perfusion of the antrum with 10% ethanol caused an immediate increase in gastrin levels in the antral venous outflow. Acidification of the perfus...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197406000-00015

    authors: Becker HD,Reeder DD,Thompson JC

    更新日期:1974-06-01 00:00:00

  • Common bile duct and Oddi sphincter pressure before and after endoscopic papillotomy in patients with common bile duct stones.

    abstract::Pressures in the Oddi sphincter and common bile duct were determined before, immediately after and several weeks after endoscopic papillotomy. Fifteen patients were included in the study. Significant decreases in Oddi sphincter and common bile duct pressures were found and the decrease in Oddi sphincter pressure was t...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197908000-00009

    authors: Funch-Jensen P,Csendes A,Kruse A,Oster MJ,Amdrup E

    更新日期:1979-08-01 00:00:00

  • Physiologic role of cholecystokinin in the intestinal phase of pancreatic polypeptide release.

    abstract::Release of pancreatic polypeptide (PP) after a meal is biphasic, with an early transient peak believed to be under cholinergic control, and a secondary, prolonged intestinal phase thought to be mediated by hormones. Endogenous release of PP was stimulated by intraduodenal oleate (6.8 mmol/hr) or by intravenous adminis...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198411000-00008

    authors: Fried GM,Ogden WD,Greeley GH Jr,Thompson JC

    更新日期:1984-11-01 00:00:00

  • Open Versus Fenestrated Endovascular Repair of Complex Abdominal Aortic Aneurysms.

    abstract:OBJECTIVE:To compare outcomes of fenestrated (FEVAR) and open repairs of complex abdominal aortic aneurysms (cAAA). BACKGROUND:FEVAR has emerged as an alternative to open surgery for treating cAAA, but direct comparisons are limited. METHODS:We studied all repairs of intact or symptomatic cAAA in the Vascular Quality...

    journal_title:Annals of surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1097/SLA.0000000000003094

    authors: O'Donnell TFX,Boitano LT,Deery SE,Schermerhorn ML,Schanzer A,Beck AW,Green RM,Takayama H,Patel VI

    更新日期:2020-05-01 00:00:00

  • Long-term results with multimodal adjuvant therapy and liver transplantation for the treatment of hepatocellular carcinomas larger than 5 centimeters.

    abstract:OBJECTIVE:To determine the long-term results of liver transplantation for hepatocellular carcinoma (HCC) measuring 5 cm or larger treated in a multimodality adjuvant protocol. SUMMARY BACKGROUND DATA:Transplant has been established as a viable treatment of HCC measuring less than 5 cm, but the results for larger tumor...

    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章

    doi:10.1097/00000658-200204000-00012

    authors: Roayaie S,Frischer JS,Emre SH,Fishbein TM,Sheiner PA,Sung M,Miller CM,Schwartz ME

    更新日期:2002-04-01 00:00:00

  • An evaluation of information transfer through the continuum of surgical care: a feasibility study.

    abstract:OBJECTIVE:To evaluate information transfer and communication (ITC) across the surgical care pathway with the use of Information Transfer and Communication Assessment Tool for Surgery (ITCAS). BACKGROUND:Communication failures are the leading cause of surgical errors and adverse events. It is vital to assess the ITC ac...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e3181e986df

    authors: Nagpal K,Vats A,Ahmed K,Vincent C,Moorthy K

    更新日期:2010-08-01 00:00:00

  • Clinical application of cytochrome a(plus a3) assay of mitochondria from liver specimens: an aid in determining metabolic tolerance of liver remnant for hepatic resection.

    abstract::Measurement of cytochrome a(+a(3)) contents in liver mitochondria was made on 52 biopsy specimens of patients with liver tumor. Patients having higher cytochrome a(+a(3)) contents in mitochondria from remaining liver than those of normal human liver mitochondria could survive well major liver resections whether or not...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-197412000-00013

    authors: Ozawa K,Yamaoka Y,Kitamura O,Nambu H,Kamiyama Y

    更新日期:1974-12-01 00:00:00

  • Long-term follow-up of a randomized trial comparing the beger and frey procedures for patients suffering from chronic pancreatitis.

    abstract:OBJECTIVE:To report on the long-term follow-up of a randomized clinical trial comparing pancreatic head resection according to Beger and limited pancreatic head excision combined with longitudinal pancreatico-jejunostomy according to Frey for surgical treatment of chronic pancreatitis. SUMMARY BACKGROUND DATA:Resectio...

    journal_title:Annals of surgery

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/01.sla.0000157268.78543.03

    authors: Strate T,Taherpour Z,Bloechle C,Mann O,Bruhn JP,Schneider C,Kuechler T,Yekebas E,Izbicki JR

    更新日期:2005-04-01 00:00:00

  • A lethally irradiated allogeneic granulocyte-macrophage colony stimulating factor-secreting tumor vaccine for pancreatic adenocarcinoma. A Phase II trial of safety, efficacy, and immune activation.

    abstract:PURPOSE:Surgical resection provides the only possibility of cure for pancreas cancer. A standard adjuvant approach has not been established. We tested the safety and efficacy of a granulocyte-macrophage colony-stimulating factor (GM-CSF)-based immunotherapy administered in patients with resected pancreatic adenocarcino...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0b013e3181fd271c

    authors: Lutz E,Yeo CJ,Lillemoe KD,Biedrzycki B,Kobrin B,Herman J,Sugar E,Piantadosi S,Cameron JL,Solt S,Onners B,Tartakovsky I,Choi M,Sharma R,Illei PB,Hruban RH,Abrams RA,Le D,Jaffee E,Laheru D

    更新日期:2011-02-01 00:00:00

  • Cryopreservation of isolated primary rat hepatocytes: enhanced survival and long-term hepatospecific function.

    abstract:OBJECTIVE:To investigate the long-term effect of cryopreservation on hepatocyte function, as well as attempt to improve cell viability and function through the utilization of the hypothermic preservation solution, HypoThermosol (HTS), as the carrier solution. SUMMARY BACKGROUND DATA:Advances in the field of bioartific...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/01.sla.0000149303.48692.0f

    authors: Sosef MN,Baust JM,Sugimachi K,Fowler A,Tompkins RG,Toner M

    更新日期:2005-01-01 00:00:00

  • Survival in Locally Advanced Pancreatic Cancer After Neoadjuvant Therapy and Surgical Resection.

    abstract:OBJECTIVE:The aim of the study was to identify the survival of patients with locally advanced pancreatic cancer (LAPC) and assess the effect of surgical resection after neoadjuvant therapy on patient outcomes. BACKGROUND:An increasing number of LAPC patients who respond favorably to neoadjuvant therapy undergo surgica...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/SLA.0000000000002753

    authors: Gemenetzis G,Groot VP,Blair AB,Laheru DA,Zheng L,Narang AK,Fishman EK,Hruban RH,Yu J,Burkhart RA,Cameron JL,Weiss MJ,Wolfgang CL,He J

    更新日期:2019-08-01 00:00:00

  • Lung vascular injury with protease infusion. Relationship to plasma fibronectin.

    abstract::Fibronectin exists in a soluble form in plasma and in an insoluble form in tissues. Plasma fibronectin can modulate phagocytic function as well as incorporate into the tissue matrix where it is believed to influence microvascular integrity and tissue repair. The temporal alterations in plasma and lung lymph fibronecti...

    journal_title:Annals of surgery

    pub_type: 杂志文章

    doi:10.1097/00000658-198508000-00016

    authors: Cohler LF,Saba TM,Lewis EP

    更新日期:1985-08-01 00:00:00