Abstract：
:The use of naltrexone results in an accelerated opiate withdrawal. By combining clonidine with naltrexone, severity of the withdrawal is modified. This paper describes the author's experience with use of this protocol in 55 episodes of opiate detoxification. Commercially available naltrexone (Trexan) and clonidine tablets were used in the setting of a medical detoxification unit. Of 55 detoxifications, 51 were successfully completed. Results confirm the clinical utility of this protocol as evidenced by rapid detoxification, minimal dropout, and induction of naltrexone maintenance.
journal_name
J Subst Abuse Treatjournal_title
Journal of substance abuse treatmentauthors
Senft RAdoi
10.1016/0740-5472(91)90048-fsubject
Has Abstractpub_date
1991-01-01 00:00:00pages
257-9issue
4eissn
0740-5472issn
1873-6483journal_volume
8pub_type
杂志文章abstract：:Progress continues to be made in clarifying neurobiological factors in alcoholism and other chemical dependencies. Research in animal behavioral genetics and human genetics has revealed substantial genetic predispositions for some cases of alcoholism. Studies of neurotransmitters suggest that some alcoholics may have ...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,评审
doi：10.1016/0740-5472(88)90043-8
更新日期：1988-01-01 00:00:00
abstract：BACKGROUND:Hepatitis C Virus (HCV) risk is elevated for individuals with an opioid use disorder (OUD). Routine HCV testing is recommended for high-risk individuals, including those with an injection drug use history. HCV antibody testing addresses the first step in the HCV treatment care cascade, with uptake and comple...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2017.01.017
更新日期：2017-05-01 00:00:00
abstract：:The purpose of this study was to examine the evidence of psychotherapeutic integrated treatment (IT) programs for individuals with concurrent substance use disorders and trauma histories. Electronic searches of Cochrane Central Register of Controlled Trials, MEDLINE, Web of knowledge, PubMed, PsycINFO, CINAHL, PILOTS,...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.jsat.2011.09.001
更新日期：2012-01-01 00:00:00
abstract：:Alprazolam appears to have an abuse liability among opiate addicts, and detoxification can be prolonged. The authors describe experience with five methadone maintenance patients who were polysubstance abusers and were admitted specifically for detoxification from alprazolam dependence. Phenobarbital in tapering doses ...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/0740-5472(90)90036-p
更新日期：1990-01-01 00:00:00
abstract：:Hazardous alcohol consumption has been frequently reported among women with HIV infection and is associated with a variety of negative health consequences. Treatments to reduce alcohol use may bring in health benefits. However, little is known regarding the utilization of alcohol treatment services among HIV+ women wi...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2016.01.011
更新日期：2016-05-01 00:00:00
abstract：:Amlodipine is a calcium-channel antagonist with neuropharmacological properties believed to be protective against cerebral hypoperfusion, microinfarcts, and excitoxic cell death. Based on its pharmacological properties, we hypothesized that amlodipine would be associated with improved attention, processing speed, memo...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jsat.2009.03.009
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:Co-occurring mental health disorders are common among substance use disorder (SUD) patients. Medicaid expansion aimed to reduce barriers to SUD and mental health care and thereby improve treatment outcomes. METHODS:We estimated change in the proportion of United States SUD treatment sites offering treatment...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2019.07.012
更新日期：2019-10-01 00:00:00
abstract：:The purpose of this study was to evaluate the efficacy of the Family Check-up (FCU), a parent-focused brief motivational intervention, in families where parents were concerned about one adolescent's alcohol or marijuana use and the referred adolescent also had a sibling close in age. The primary goal of the FCU was to...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jsat.2017.02.002
更新日期：2017-06-01 00:00:00
abstract：BACKGROUND:Chronic opioid misuse is associated with reduced sensitivity to natural rewards and social motivation deficits that include impaired caregiving. The neurobiological mechanisms underlying these deficits and their response to treatment are not well understood. Baby schema (Kindchenschema) is a set of juvenile ...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2017.10.007
更新日期：2018-02-01 00:00:00
abstract：:Few studies have investigated the impact of adolescent change language on substance use treatment outcomes and even fewer have examined how adolescents respond to normative feedback. The purpose of this study was to understand the influence normative feedback has on adolescent change language and subsequent alcohol an...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jsat.2015.10.004
更新日期：2016-06-01 00:00:00
abstract：:Adolescence is a period of rapid biological, psychological, and social development in the human life cycle. Drug and alcohol misuse during this critical period poses substantial problems for individual and public health, yet is highly prevalent in the United States and elsewhere. The screening, brief interventions, an...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,评审
doi：10.1016/j.jsat.2012.11.005
更新日期：2013-05-01 00:00:00
abstract：BACKGROUND AND AIMS:High drug related mortality amongst former prisoners in the 4 weeks following release is an internationally recognised problem. Naltrexone injections at release could diminish this by blockading opioid receptors, but naltrexone is not licensed for injection for treating opiate misuse in the United K...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2018.07.002
更新日期：2018-09-01 00:00:00
abstract：:To better understand residential detoxification use, we assessed the roles of depressive symptoms (DS) and mental health functioning (MHF) on repeat detoxification. A prospective cohort of residential detoxification patients (N=400) without primary medical care was followed over 2 years at 6-month intervals. Subsequen...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2005.05.005
更新日期：2005-09-01 00:00:00
abstract：:This article addresses the relation between services matched to client-identified needs and substance abuse treatment outcomes for women with children. The study uses data collected for a program evaluation of an enhanced substance abuse services program for mothers involved with the child welfare system. In-person su...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/s0740-5472(02)00229-5
更新日期：2002-04-01 00:00:00
abstract：BACKGROUND:The United States is in the middle of an opioid overdose epidemic, and experts are calling for improved detection of opioid use disorders (OUDs) and treatment with buprenorphine or extended release (XR) injectable naltrexone, which can be prescribed in general medical settings. To better understand the magni...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2020.02.001
更新日期：2020-03-01 00:00:00
abstract：:This article focuses on the problem of treatment resistance in women. Causes are explored, including psychological and situational factors. Techniques for recognizing and reducing resistance are offered, including implications for treatment planning and program design. Counselors are given a sense of perspective that ...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/0740-5472(84)90052-7
更新日期：1984-01-01 00:00:00
abstract：OBJECTIVE:The current study examined the role of perceived treatment need in explaining racial/ethnic disparities in treatment utilization for a substance use disorder (SUD). METHODS:We pooled data from the National Survey on Drug Use and Health survey for years 2014-2017. The analytic sample included adult white, Bla...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2020.108105
更新日期：2020-11-01 00:00:00
abstract：:The increasing prevalence of opioid use disorders among pregnant and postpartum women (PPW) has generated a need for greater availability of specialized programs offering evidence-based and comprehensive substance use disorder treatment services tailored to this population. In this study, we used data from the 2007 to...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2019.12.005
更新日期：2020-03-01 00:00:00
abstract：:This paper presents findings on the impact of implementing a parenting component in two urban residential treatment programs in Massachusetts for pregnant and parenting chemically-dependent women. The parenting component consisted of multiple services for both women and their infants while they were in residential tre...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/s0740-5472(97)00004-4
更新日期：1997-09-01 00:00:00
abstract：:In the context of the COVID-19 pandemic and the state of emergency that the government of Spain declared, the rapid adaptation of health services is of paramount importance to preserve access to and continuity of service delivery. This research note underscores the importance of ensuring a sufficient quantity of metha...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2020.108154
更新日期：2020-12-01 00:00:00
abstract：:Runaway/homeless shelters document high levels of substance abuse among runaway youth, at least double that of school youth. These youth present a constellation of problems and research suggests that this population may be unique in the range and intensity of associated problems. Most studies to date have collected se...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/s0740-5472(00)00100-8
更新日期：2000-10-01 00:00:00
abstract：OBJECTIVES:Previous research has documented the difficulty individuals with alcohol use disorders have initiating alcohol treatment. This study assessed the feasibility of a brief, cognitive-behavioral intervention designed to increase treatment initiation among individuals with alcohol use disorders. METHODS:This ran...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jsat.2011.10.028
更新日期：2012-09-01 00:00:00
abstract：:Data on minimum state requirements for drug and alcohol counselors and mental health counselors in all 50 states and Washington, DC, suggest that training as a mental health counselor is primarily structured through formal education, whereas training as a substance abuse counselor resembles an apprentice model. Fewer ...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2005.11.004
更新日期：2006-04-01 00:00:00
abstract：:Females incarcerated for drug-related offenses represent one of the fastest growing populations within jails and prisons. The few studies of female offenders with substance abuse disorders depict a population with multiple psychosocial problems and treatment needs, and one that is characterized by frequent exposure to...
journal_title：Journal of substance abuse treatment
pub_type： 临床试验,杂志文章
doi：10.1016/s0740-5472(97)00003-2
更新日期：1997-07-01 00:00:00
abstract：:For many individuals, substance use leads to a chronic cycle of relapse, treatment reentry, and recovery, often lasting for decades. This study replicates earlier work, documents the transition patterns within the cycle during a 3-year period, and identifies variables that predict these transitions. Data are from 1,32...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2004.09.006
更新日期：2005-01-01 00:00:00
abstract：:The comorbidity of attention deficit hyperactivity disorder (ADHD) is frequently not well recognized in substance abuse treatment institutions in The Netherlands. As a consequence, patients with substance use disorder (SUD) and ADHD often receive suboptimal treatment. To prevent every treatment center from having to i...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2005.12.004
更新日期：2006-04-01 00:00:00
abstract：:There has been a rise in illicit drug smoking in the United States. "Shotgunning" drugs (or "doing a shotgun") refers to the practice of inhaling smoke and then exhaling it into another individual's mouth, a practice with the potential for the efficient transmission of respiratory pathogens. Three hundred fifty-four d...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/s0740-5472(96)00182-1
更新日期：1997-01-01 00:00:00
abstract：:Despite a dramatic increase in the nonmedical use of prescription drugs among illicit drug users, their motives for abusing prescription drugs are still largely unknown. The objective of this study was to (a) determine the motivations for engaging in the nonmedical use of prescription opioids and sedatives among stree...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2010.06.004
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND:Remission from alcohol problems in the absence of treatment is common, yet there are wide ranging estimates of the extent to which this occurs, depending on method. A systematic review of the literature on untreated remission from alcohol problems was conducted to analyse the ways different definitions and s...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2019.04.004
更新日期：2019-07-01 00:00:00
abstract：:This study examined the prevalence of exposure to violence among drug-dependent pregnant women attending a multidisciplinary perinatal substance abuse treatment program. Participants (N = 715) completed the Violence Exposure Questionnaire within 7 days after their admission to the program. Their rates of lifetime abus...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2005.09.001
更新日期：2006-01-01 00:00:00
