Abstract:
:Progress continues to be made in clarifying neurobiological factors in alcoholism and other chemical dependencies. Research in animal behavioral genetics and human genetics has revealed substantial genetic predispositions for some cases of alcoholism. Studies of neurotransmitters suggest that some alcoholics may have antecedent deficiencies in one or more important neurochemical systems. Cocaine dependence is considered to be related to biphasic change in dopaminergic neurons and receptor systems. Condensation products such as salsolinol, tetrahydropapaveroline, and beta carbolines can alter alcoholic preference and motivate heavy ethanol consumption in animals. However, hypothesized theoretical mechanisms underlying such increased drinking with infusions of condensation products are unclear and may require revision. New pharmacological treatments stemming from advances in neurobiological research have been applied successfully to treatment of withdrawal states, but none have been demonstrated to be appropriate for long-term maintenance of abstinence.
journal_name
J Subst Abuse Treatjournal_title
Journal of substance abuse treatmentauthors
Wallace Jdoi
10.1016/0740-5472(88)90043-8subject
Has Abstractpub_date
1988-01-01 00:00:00pages
207-17issue
4eissn
0740-5472issn
1873-6483journal_volume
5pub_type
杂志文章,评审abstract::This study examined the efficacy of brief alcohol intervention in the context of community-based treatment for partner violence. In a randomized clinical trial, 228 partner-violent men with hazardous or problem drinking were recruited at three Intimate Partner Violence (IPV) treatment agencies and randomly assigned to...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jsat.2018.03.004
更新日期:2018-06-01 00:00:00
abstract:INTRODUCTION:Transgender (trans) people experience stressors related to their minority status which have been associated with increased rates of psychoactive substance use and related harm. Despite this, there is a paucity of evidence relating to the treatment needs of trans people who use psychoactive substances, beyo...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2020.03.001
更新日期:2020-05-01 00:00:00
abstract::We explored patient, therapist, and program variability in the alliance in relation to drug and alcohol use during treatment, and whether alliance mediates the relation of program characteristics to drug/alcohol use. Data (N = 1,613 patients) were drawn from a randomized clinical trial investigating the efficacy of an...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2011.01.003
更新日期:2011-06-01 00:00:00
abstract::Methadone Transition Treatment (MTT) is a treatment program for opioid-addicted individuals that takes advantage of a 1989 change in federal guidelines permitting the establishment of 180-day detoxification programs. Thirty-eight subjects were assigned to either high-dose (80 mg) or low-dose (40 mg) methadone in a dou...
journal_title:Journal of substance abuse treatment
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0740-5472(94)90079-5
更新日期:1994-05-01 00:00:00
abstract::Hospitalized patients have high rates of unhealthy substance use, which has important impacts on health both during and after hospitalization, but is infrequently identified in the absence of screening. The Substance Use Brief Screen (SUBS) was developed as a brief, self-administered instrument to identify use of toba...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2017.05.014
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Insomnia and other types of sleep disturbance are highly prevalent during withdrawal across many different types of substance use disorders (SUDs). It is largely unknown how sleep impacts SUD treatment outcomes, including treatment completion. METHODS:A retrospective chart review was conducted to obtain inf...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2019.06.003
更新日期:2019-09-01 00:00:00
abstract::We review the problems unique to the diagnosis and treatment of patients who suffer both major mental illness and alcohol/drug abuse. We describe the experience and the approach evolved in the Special Treatment Team, a State Hospital unit that has specialized in this work. We discuss in detail the assessment and stabi...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章,评审
doi:10.1016/0740-5472(88)90044-x
更新日期:1988-01-01 00:00:00
abstract::The problem of substance abuse in pregnancy is a major public health dilemma. Effective comprehensive care of drug addicted women has been shown to improve maternal and neonatal outcomes. The Center for Addiction and Pregnancy (CAP) combines the disciplines of pediatrics, substance abuse treatment, obstetrics/gynecolo...
journal_title:Journal of substance abuse treatment
pub_type: 临床试验,杂志文章
doi:10.1016/s0740-5472(96)00070-0
更新日期:1996-07-01 00:00:00
abstract::The design and implementation of a personality assessment system for severely substance-dependent men in a therapeutic community (TC) are described. The system was designed from a treatment utility perspective (Hayes, Nelson, & Jarrett, 1987) and uses the Personality Research Form E (Jackson, 1984) to provide each pat...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/0740-5472(96)00030-x
更新日期:1996-03-01 00:00:00
abstract:BACKGROUND:While patients with substance use disorders (SUDs) are thought to encounter poor primary care experiences, the perspectives of patients with opioid use disorder (OUD), specifically, are unknown. This study compares the primary care experiences of patients with OUD, other SUDs and no SUD in the Veterans Healt...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2020.02.013
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:The National Drug Abuse Treatment Clinical Trials Network (CTN) multisite comparative-effectiveness study ("X:BOT") by Lee et al. (2018) found that, once initiated, extended-release naltrexone (XR-NTX) is as similarly safe and effective as sublingual buprenorphine-naloxone (BUP-NX) for the treatment of opioi...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2020.108183
更新日期:2021-03-01 00:00:00
abstract::Workers in drug treatment programs need specialized training concerning acquired immune deficiency syndrome (AIDS) to meet the demands of their expanding roles. Initially, the treatment community failed to anticipate training needs fully, but now, comprehensive and systematic AIDS training programs must be developed. ...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/0740-5472(92)90005-9
更新日期:1992-01-01 00:00:00
abstract::The goal of this study was to compare the effects of 1, 3 and 8 mg per day doses of buprenorphine in the maintenance treatment of opium-dependent subjects in Iran over a treatment period of 12 months. Participants were randomized to three equal groups (171 subjects per group) of opium-dependent individuals who met the...
journal_title:Journal of substance abuse treatment
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0740-5472(03)00141-7
更新日期:2004-01-01 00:00:00
abstract::Smoking is endemic in drug abuse treatment populations, and smoking prevalence in this population appears unresponsive to existing tobacco control strategies. Clinical and policy guidelines encourage programs to address smoking among clients, and research has identified key barriers to doing so. This report explores t...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2017.01.014
更新日期:2017-05-01 00:00:00
abstract::Substance abuse treatment providers commonly provide services for men and women involved in sex work. Sex workers often present to treatment with a complicated array of challenges (M. L. Burnette et al., 2008a; D. C. Ling, W. C. W. Wong, E. A. Holroyd, & S. A. Grayson, 2007; M. Young, C. Boyd, & A. Hubbell, 2000), and...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2013.01.013
更新日期:2013-08-01 00:00:00
abstract::The clinical diagnoses of comorbid substance use and psychiatric disorders by psychiatrists in a private psychiatric inpatient setting were analyzed. Two hundred patients consecutively discharged from a private university-affiliated psychiatric service by clinical psychiatrists were examined for concomitant substance ...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/0740-5472(94)90050-7
更新日期:1994-07-01 00:00:00
abstract::Recovery coaches, trained peers with a history of substance use disorder (SUD) who are formally embedded in the health care team, may be a cost-effective approach to support outpatient management of SUD treatment. Although recovery coach programs are scaling nationwide, limited data exist to support their impact on co...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2020.108248
更新日期:2021-03-01 00:00:00
abstract:BACKGROUND AND AIMS:Although central to the hepatitis C virus (HCV) epidemic, many patients with both substance use disorders (SUD) and HCV have difficultly engaging in treatment for either condition. To facilitate HCV care in Veterans with active SUD, a comprehensive HCV screening, education, referral, and treatment p...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2018.11.008
更新日期:2019-03-01 00:00:00
abstract::The purpose of this study was to evaluate the efficacy of the Family Check-up (FCU), a parent-focused brief motivational intervention, in families where parents were concerned about one adolescent's alcohol or marijuana use and the referred adolescent also had a sibling close in age. The primary goal of the FCU was to...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jsat.2017.02.002
更新日期:2017-06-01 00:00:00
abstract::Following research indicating that the treatment needs of women are different from those of men, researchers and clinicians have argued that drug treatment programs for women should be designed to take their needs into account. Such programs tend to admit only women and incorporate philosophies and activities that are...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2010.12.001
更新日期:2011-06-01 00:00:00
abstract::Seven hundred thirty-two volunteer participants enrolled in 35 substance abuse treatment facilities across the United States were surveyed to examine the prevalence and nature of incest contacts among adults receiving substance abuse treatment. Results indicated that approximately 36% of the sample reported histories ...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/s0740-5472(96)00054-2
更新日期:1996-05-01 00:00:00
abstract::Providing unobserved opioid substitution treatment (OST) safely is a major challenge. This study examined whether electronic medicine dispensers (EMDs) can reduce diversion of take-home buprenorphine-naloxone (BNX) in a medium-sized Finnish city. All BNX treated OST patients in Kuopio received their take-home BNX in E...
journal_title:Journal of substance abuse treatment
pub_type: 临床试验,杂志文章
doi:10.1016/j.jsat.2013.01.003
更新日期:2013-07-01 00:00:00
abstract::Opioid medication treatment access is a public health priority aimed to improve opioid use treatment outcomes. However, Medicaid does not cover all forms of MOUD, particularly methadone, in many states. We examined associations between medication for opioid use disorder (MOUD) plans and substance use treatment dischar...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2020.108028
更新日期:2020-07-01 00:00:00
abstract::The feasibility of using extended-release injectable naltrexone (XR-NTX) to treat alcohol dependence in routine primary care settings is unknown. An open-label, observational cohort study evaluated 3-month treatment retention, patient satisfaction, and alcohol use among alcohol-dependent patients in two urban public h...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2010.03.005
更新日期:2010-07-01 00:00:00
abstract::In 2006, the Medicare program covered 37 million elderly persons and 7 million persons younger than 65 years, but little is known about substance abuse (SA) service utilization. Using the 5% Sample of Medicare claims data, the study examines individuals who used SA detoxification ("detox") and/or rehabilitation ("reha...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2008.08.007
更新日期:2009-06-01 00:00:00
abstract::This article presents an analysis of logical inconsistencies in adolescents' reporting of recent substance use to assess the potential effect of inaccurate reporting on measures of treatment outcomes and program performance. We used data on 1,463 clients from 10 adolescent treatment programs to assess the relationship...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2007.05.004
更新日期:2008-04-01 00:00:00
abstract::It is a common belief that a massive effort in law enforcement, preventive education and rehabilitation will result in the elimination of a country's drug problem. Based on this premise. Malaysia in 1983 implemented such a multifaceted anti-drug strategy, and the results of a 1987 study by the author suggested that Ma...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/0740-5472(92)90087-5
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:Chronic opioid misuse is associated with reduced sensitivity to natural rewards and social motivation deficits that include impaired caregiving. The neurobiological mechanisms underlying these deficits and their response to treatment are not well understood. Baby schema (Kindchenschema) is a set of juvenile ...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2017.10.007
更新日期:2018-02-01 00:00:00
abstract::The turbulence created by the emergence of managed care has increased the importance of staff retention for substance abuse treatment centers. This study examines the relationships between management practices, organizational commitment, and turnover intention among substance abuse treatment counselors. Counselors fro...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/s0740-5472(02)00357-4
更新日期:2003-03-01 00:00:00
abstract::This article describes concrete strategies for conducting substance abuse research with ethnic minorities. Two issues associated with valid analysis, measurement and data analysis, are included. Both empirical (e.g., confirmatory factor analysis, item response theory, and regression) and nonempirical (e.g., focus grou...
journal_title:Journal of substance abuse treatment
pub_type: 杂志文章
doi:10.1016/j.jsat.2008.04.003
更新日期:2009-01-01 00:00:00