Preoperative hormonal therapy of cystic adnexal masses.

Abstract:

:286 patients between ages 16-48 with cystic adnexal masses were treated with estrogen and progesterone for 6 weeks. Persistence of the adnexal mass occurred in 81 patients and surgical exploration was done. All patients explored with an ovarian enlargement had an ovarian neoplasm causing the enlargement. There were 7 patients with normal sized ovaries but an associated paraovarian cyst or unilateral hydrosalpinx was found. No patient was subjected to surgical exploration with the finding of a physiologic cyst causing the adnexal mass. In this series, suppression of the pituitary gonadotropins for 6 weeks was long enough to cause all significant physiologic cysts to regress. It would seem that menstruating women with a cystic adnexal mass and a differential diagnosis that included a physiologic cyst should not be subjected to operations without a trial of pituitary suppressions. Also, the use of pituitary suppression with estrogen and progesterone removes indecision as to how long a physiologic cyst will remain before undergoing regression.

journal_name

Am J Obstet Gynecol

authors

Spanos WJ

doi

10.1016/0002-9378(73)90913-7

subject

Has Abstract

pub_date

1973-06-15 00:00:00

pages

551-6

issue

4

eissn

0002-9378

issn

1097-6868

pii

0002-9378(73)90913-7

journal_volume

116

pub_type

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