Abstract：
:In CO2 chemosensitive neurons, an increase in CO2 (hypercapnia) leads to a maintained reduction in intracellular pH (pH(i)) while in non-chemosensitive neurons pH(i) recovery is observed. The precise mechanisms for the differential regulation of pH(i) recovery between these cell populations remain to be identified; however, studies have begun to explore the role of Na+/H+ exchange (NHE). Here, we compare the results of two different formulations of a mathematical model to begin to explore pH(i) regulation in central CO2 chemoreception.
journal_name
Adv Exp Med Bioljournal_title
Advances in experimental medicine and biologyauthors
Cordovez JM,Clausen C,Moore LC,Solomon ICdoi
10.1007/978-0-387-73693-8_53subject
Has Abstractpub_date
2008-01-01 00:00:00pages
306-11eissn
0065-2598issn
2214-8019journal_volume
605pub_type
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