Abstract:
OBJECTIVE:To study interhemispheric differences of somatosensory evoked field (SEF) characteristics and the spatial distribution of equivalent current dipole sources in patients with unilateral hemispheric lesions around the central sulcus region. METHODS:In 17 patients with perirolandic lesions, averaged somatosensory responses after posterior tibial nerve stimulation at the ankle were recorded with magnetoencephalography. Dipole source solutions in the affected (AH) and unaffected (UH) hemispheres were analyzed and compared for latency, equivalent current dipole strength, root mean square, and spatial distribution in relation to clinical findings. RESULTS:Three main SEF components, P45m, N60m, and P75m, were identified in the hemisphere contralateral to the stimulated nerve. Dipole strength for the P45m component was significantly higher in the AH compared with the UH. SEF characteristics in the AH and UH showed no significant differences with respect to component latency or dipole strength of the N60m and P75m components. Interdipole location asymmetries exceeded 1.0 cm in 71% of the patients. Comparison of the posterior tibial nerve evoked responses (P45m and N60m) in patients with motor deficits and patients without deficits showed that these responses are enlarged in the AH when perirolandic lesions are present. Patients with motor deficits also showed an increased response for P45m in the UH. CONCLUSION:The results of posterior tibial nerve SEFs suggest spatial and functional changes in the somatosensory network as a result of perirolandic lesions with a possible relationship with clinical symptoms. The results can provide further basis for the evaluation of cortical changes in the presence of perirolandic lesions.
journal_name
Neurosurgeryjournal_title
Neurosurgeryauthors
Willemse RB,de Munck JC,van't Ent D,Ris P,Baayen JC,Stam CJ,Vandertop WPdoi
10.1227/01.neu.0000306099.45764.5csubject
Has Abstractpub_date
2007-12-01 00:00:00pages
1209-17; discussion 1217-8issue
6eissn
0148-396Xissn
1524-4040pii
00006123-200712000-00011journal_volume
61pub_type
杂志文章相关文献
NEUROSURGERY文献大全abstract::A compound of methylcellulose-silicone expanding progressively over a 1-week period by moisture absorption was implanted in the midthoracic epidural space of 17 Sprague Dawley adult rats. When the animals became paraplegic 6.3 +/- 1.6 days later, they were randomized into three groups: untreated control (n = 5), high ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-198806010-00005
更新日期:1988-06-01 00:00:00
abstract:BACKGROUND:Cerebral cavernous malformations (CCM) may lead to repetitive intracerebral hemorrhage. In selected cases, a surgical resection is indicated. OBJECTIVE:To identify magnetic resonance imaging (MRI) features of CCM that correlate with the difficulty of dissection and postoperative outcome. METHODS:This study...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1093/neuros/nyx025
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:To review the natural history and determine the rates of intra- and extralesional hemorrhaging of brainstem cavernous malformations (cavernomas) monitored by one neuro-ophthalmology service. METHODS:A record review of all patients with brainstem cavernomas who were evaluated by a neuroophthalmology service b...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-200101000-00007
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:We report the safety and feasibility of using convection-enhanced delivery to administer Cotara (Peregrine Pharmaceuticals, Inc., Tustin, CA), a novel radioimmunotherapeutic agent, to patients with malignant glioma. METHODS:Between April 1998 and November 2002, 51 patients with histologically confirmed malig...
journal_title:Neurosurgery
pub_type: 杂志文章,多中心研究
doi:10.1227/01.neu.0000159649.71890.30
更新日期:2005-06-01 00:00:00
abstract:OBJECTIVE AND IMPORTANCE:The endovascular treatment of carotid-cavernous dural fistulae is becoming the prominent treatment modality for these lesions. The intractability of these lesions and their tendency to recur, especially after previous endovascular treatment sessions, exhausts the available routes and tends to p...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199902000-00113
更新日期:1999-02-01 00:00:00
abstract:BACKGROUND:Brain metastases represent the most common intracranial tumors and are associated with very poor prognosis. OBJECTIVE:To investigate the feasibility, survival, and cerebral disease control of patients with singular brain metastases treated with stereotactic 125iodine brachytherapy (SBT), to identify prognos...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0b013e31820b526a
更新日期:2011-05-01 00:00:00
abstract::We studied the effects of combination treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and low dose rate radiation in the 9L rat brain tumor in vivo model and the 9L multicellular tumor spheroid model. F-344 rats bearing intracerebral 9L gliosarcomas were implanted with removable 125I sources. Minimal (perip...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:
更新日期:1984-12-01 00:00:00
abstract:BACKGROUND:Revascularization rates with stent retrievers after acute ischemic stroke are 69% to 86%, but favorable clinical outcomes occur in just 43% to 58% of cases. New distal emboli may negatively impact clinical outcomes. OBJECTIVE:To determine the prevalence and angiographic pattern of distal emboli associated w...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0000000000001135
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Endovascular coil embolization of ruptured aneurysms is performed under general anesthesia at most centers for perceived improved image quality and patient safety. OBJECTIVE:To report the feasibility of and outcomes associated with endovascular treatment of subarachnoid hemorrhage (SAH) patients with ruptur...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0b013e31827b9183
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:If patients with idiopathic normal pressure hydrocephalus (INPH) also have depression, this could have important clinical ramifications in assessment and management of their cognitive function and response to shunting. In many dementias, depression is overrepresented, but the prevalence of depression in shun...
journal_title:Neurosurgery
pub_type: 杂志文章,多中心研究
doi:10.1227/NEU.0000000000001093
更新日期:2016-02-01 00:00:00
abstract::We report a case of a cerebral arteriovenous malformation presenting as a pseudotumor cerebri syndrome. The lack of mass effect, hemorrhage, or hydrocephalus, in addition to angiographic evidence of high-flow and venous outflow restriction, implicate increased cerebral blood flow and venous hypertension as the mechani...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1227/00006123-199503000-00020
更新日期:1995-03-01 00:00:00
abstract:BACKGROUND:Limited dorsal myeloschisis (LDM) is postulated to be a result of incomplete dysjunction in primary neurulation. However, clinical experience of LDM located below the first-second sacral (S1-S2) vertebral level, which is formed from secondary neurulation (S2-coccyx), suggested that LDM may not be entirely ex...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1093/neuros/nyy632
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:To study the distribution of intracranial arachnoid cysts in a large and nonbiased patient population. METHODS:One hundred twenty-six patients with 132 arachnoid cysts were studied. Patients were consecutively referred to our department during a 10-year period from a well-defined geographical area with a sta...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199910000-00008
更新日期:1999-10-01 00:00:00
abstract::The diagnosis of malignant glioma of the optic nerves and chiasm may be difficult because these rare lesions may mimic other suprasellar lesions. We report a case of glioblastoma multiforme of the optic chiasm in which the appearance of the lesion on computed tomographic (CT) scan was consistent with that of craniopha...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-198212000-00011
更新日期:1982-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the safety and any potential effect of cyclosporine A (CycA) in preventing cerebral vasospasm. METHODS:Nine patients with Fisher Grade 3 subarachnoid hemorrhages were studied. After a loading dose of 7.5 mg/kg of CycA was administered every 12 hours for two doses, enteral treatment with CycA was ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199702000-00010
更新日期:1997-02-01 00:00:00
abstract:OBJECTIVE:Fever is associated with worse outcome after subarachnoid hemorrhage, but there are few prospective data to quantify this relationship. METHODS:We prospectively enrolled consecutive aneurysmal or cryptogenic subarachnoid hemorrhage patients and recorded the highest core temperature each calendar day for Day ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.NEU.0000320453.61270.0F
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVE:There are numerous reports on the surgical treatment of trigeminal neuralgia, but the studies do not use uniform outcome measures, which makes it difficult for patients and clinicians to determine which treatment may be most appropriate. The objectives of this study were to set quality criteria and standards ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.neu.0000068862.78930.ee
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:The supraorbital keyhole approach has been used in anterior skull base tumor and aneurysm surgery. However, there are debates regarding the safety and limitations of this kind of approach. OBJECTIVE:To determine the feasibility and potential benefits of surgical robotic technology in minimally invasive neur...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/NEU.0b013e318270d9de
更新日期:2013-01-01 00:00:00
abstract::Pyogenic brain stem abscess is rare. A case of spontaneous abscess of the medulla oblongata is reported in which the diagnosis was made preoperatively by computed tomography. Surgical drainage resulted in good functional recovery and radiological resolution of the lesion. This is the first reported case of survival in...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-198603000-00024
更新日期:1986-03-01 00:00:00
abstract:OBJECTIVE:Vascular endothelial growth factor (VEGF)/vascular permeability factor (VPF) is a potent angiogenic growth factor implicated in the tumor angiogenesis/metastasis of a number of human cancers. Activation of receptors for VEGF/VPF is specifically mitogenic to endothelial cells and increases their permeability. ...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199705000-00027
更新日期:1997-05-01 00:00:00
abstract:BACKGROUND:Older age has been associated with worse outcomes in low-grade gliomas (LGGs). Given their rarity in the older population, determining optimal treatment plans and patient outcomes remains difficult. OBJECTIVE:To retrospectively study LGG survival outcomes in an older population stratified by molecular genet...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1093/neuros/nyy149
更新日期:2019-02-01 00:00:00
abstract::Spread of spinal cord glioblastoma multiforme to the intracranial compartment is uncommon. This report documents a case of metastatic spread of glioblastoma multiforme from the spinal cord to an intracranial arachnoid cyst. Seeding of the cyst cavity could have occurred by direct permeation of the cyst wall by the neo...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/00006123-198705000-00018
更新日期:1987-05-01 00:00:00
abstract::Intracranial electrical recordings and stimulation of neurosurgical patients have been central to the advancement of human neuroscience. The use of these methods has rapidly expanded over the last decade due to theoretical and technical advances, as well as the growing number of neurosurgical patients undergoing funct...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1093/neuros/nyx361
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:Nonvestibular schwannomas are uncommon tumors of the brain. Trigeminal nerve schwannomas are the most common of this group, followed by glossopharyngeal, vagal, facial, accessory, hypoglossal, oculomotor, trochlear, and abducens nerve schwannomas, in descending order of frequency. We present a series of nonve...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-200203000-00002
更新日期:2002-03-01 00:00:00
abstract:OBJECTIVE:Patients with multiple sclerosis (MS) have a relatively high incidence of tic douloureux (TD) and often do not tolerate medical therapy well. The minimally invasive nature of percutaneous retrogasserian glycerol rhizotomy (PRGR) renders it ideal for first-line surgical treatment of TD. We sought to ascertain ...
journal_title:Neurosurgery
pub_type: 杂志文章,评审
doi:10.1227/01.neu.0000153907.43563.ff
更新日期:2005-03-01 00:00:00
abstract:BACKGROUND:The goals of treating Koos grade IV vestibular schwannomas are to relieve brainstem compression, preserve or restore neurological function, and achieve long-term tumor control while minimizing tumor- and treatment-related morbidity. OBJECTIVE:To propose a treatment paradigm involving the intentional near-to...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1093/neuros/nyx143
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Pediatric aneurysms are rare and complex to treat. Long-term angiographic and clinical data after microsurgical or endovascular therapies are lacking. OBJECTIVE:To study the clinical and radiographic outcomes in aneurysms in pediatric patients treated with microsurgery. METHODS:Between 1989 and 2005, 48 pa...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.NEU.0000371727.71991.64
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:The Centers for Disease Control and Prevention have called for studies detailing the prevalence and burden of mild traumatic brain injury (mTBI) in the outpatient clinical setting. OBJECTIVE:The aim of this study was to describe the prevalence of outpatient visits for minor head injury and compare the numbe...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1227/01.neu.0000429846.14579.41
更新日期:2013-07-01 00:00:00
abstract::Magnetic resonance neurography was used to directly image cervical spinal nerves in patients with clinical and radiographic evidence of cervical radiculopathy. A magnetic resonance imaging phased-array coil system was used to obtain high-resolution coronal T1-weighted spin echo, coronal/axial T2-weighted fast spin ech...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199603000-00013
更新日期:1996-03-01 00:00:00
abstract:OBJECTIVE:A quantitative analysis of intraoperative cortical shift and deformation was performed to gain a better understanding of the nature and extent of this problem and the resultant loss of spatial accuracy in surgical procedures coregistered to preoperative imaging studies. METHODS:Three-dimensional feature trac...
journal_title:Neurosurgery
pub_type: 杂志文章
doi:10.1097/00006123-199810000-00010
更新日期:1998-10-01 00:00:00