Basal cell tumor with apocrine differentiation: apocrine epithelioma.

abstract：BACKGROUND:Vitamin D3 analogs have been found to be effective in treating psoriasis. OBJECTIVE:We attempted to identify the targets and actions of vitamin D3 in the skin and to explore the availability of synthetic vitamin D3 analogs with selective actions on particular cell types or cell functions. METHODS:A review ...

journal_title：Journal of the American Academy of Dermatology

authors： Kragballe K

更新日期：1997-09-01 00:00:00

abstract：:Twenty percent of Americans will be over age 65 by 2030,1 and without a dedicated geriatrics curriculum in many residency trainings programs, dermatologists may be less familiar with age-associated side effects of common dermatologic medications. Herein, we provide a practical guide and clinical safety pearls for the ...

journal_title：Journal of the American Academy of Dermatology

authors： Grinnell M,Price KN,Shah A,Butler D

更新日期：2021-01-16 00:00:00

abstract：BACKGROUND:Gorlin-Goltz syndrome (GGS) is an autosomal-dominant disease characterized by the early onset of multiple basal cell carcinomas (BCCs), among other findings. Clinically, the BCCs may appear as soft pedunculated neoplasms that can be mistaken for true acrochordons. OBJECTIVE:We sought to describe the dermato...

journal_title：Journal of the American Academy of Dermatology

authors： Feito-Rodríguez M,Sendagorta-Cudós E,Moratinos-Martínez M,González-Beato MJ,de Lucas-Laguna R,Pizarro A

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Moderate-to-severe atopic dermatitis (AD) is increasingly recognized as a systemic disease, largely due to proteomic blood studies. There are growing efforts to develop AD biomarkers using minimal tissues. OBJECTIVE:To characterize the AD skin proteomic signature and its relationship with the blood proteome...

journal_title：Journal of the American Academy of Dermatology

authors： Pavel AB,Zhou L,Diaz A,Ungar B,Dan J,He H,Estrada YD,Xu H,Fernandes M,Renert-Yuval Y,Krueger JG,Guttman-Yassky E

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Epidermolysis bullosa (EB) is a family of 23 genetic skin disorders for which treatments are mainly supportive. Graftskin is a bilayered living human skin construct characterized by a normal expression profile of all the genes reported as mutant in EB. OBJECTIVE:The objective of this study was to evaluate t...

journal_title：Journal of the American Academy of Dermatology

authors： Fivenson DP,Scherschun L,Choucair M,Kukuruga D,Young J,Shwayder T

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:The clinical studies of series of children with herpes zoster (HZ) are rather limited. OBJECTIVE:The purpose of this study was to evaluate the epidemiologic conditions, clinical manifestations, therapy, and outcome of HZ in children. METHODS:Twenty-one patients with HZ have been studied. Five patients who ...

journal_title：Journal of the American Academy of Dermatology

authors： Kakourou T,Theodoridou M,Mostrou G,Syriopoulou V,Papadogeorgaki H,Constantopoulos A

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:Reports of necrobiotic granulomas or granuloma annulare in patients with malignant lymphoma are rare. OBJECTIVE:Our intent was to determine any unique clinical or histopathologic features in patients with granuloma annulare and lymphoma. METHODS:We reviewed the medical records and biopsy material from 13 p...

journal_title：Journal of the American Academy of Dermatology

authors： Barksdale SK,Perniciaro C,Halling KC,Strickler JG

更新日期：1994-07-01 00:00:00

abstract：:Magnification of histologic and ultrastructural photoimages is frequently misrepresented in published reports. "Power," P, the usual mode of representation of magnification, is defined as the ratio of the distance between two points on the photoimage to that between the same two points on the original specimen, but is...

journal_title：Journal of the American Academy of Dermatology

authors： Lambert WC,Lambert MW

更新日期：1985-09-01 00:00:00

abstract：:It has been demonstrated recently in mycosis fungoides and lichen planus that T lymphocyte subsets may be identified in cutaneous lymphocytic infiltrates using the immunoperoxidase technic in conjunction with monoclonal antibodies produced by the technic of Kohler and Milstein. This communication describes the applica...

journal_title：Journal of the American Academy of Dermatology

authors： McMillan EM,Wasik R,Everett MA

更新日期：1982-01-01 00:00:00

abstract：:Retinoids, synthetic vitamin A analogs, stimulate mucous metaplasia and gap-junction proliferation in embryonic and neoplastic epidermis. Such effects demonstrate that vitamin A has potent effects on epidermal differentiation. Oddly, however, retinoid action in normal postnatal tissues, where these drugs are used clin...

journal_title：Journal of the American Academy of Dermatology

authors： Elias PM

更新日期：1986-10-01 00:00:00

abstract：:Vulvar melanosis is a condition in which intensely pigmented irregular macules, clinically mimicking malignant melanoma, appear on the vulva. A biopsy specimen shows only marked lower epidermal pigmentation without any melanocytic atypia or nesting. The process is benign, and reassurance is the only treatment. ...

journal_title：Journal of the American Academy of Dermatology

authors： Rudolph RI

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Preventing fetal exposure to isotretinoin is an important public health goal. Since approval of isotretinoin (1982), the Food and Drug Administration has implemented several unsuccessful risk management programs aimed at preventing fetal exposure. The Kaiser Permanente isotretinoin risk management program in...

journal_title：Journal of the American Academy of Dermatology

authors： Cheetham TC,Wagner RA,Chiu G,Day JM,Yoshinaga MA,Wong L

更新日期：2006-09-01 00:00:00

abstract：:Adult T-cell leukemia/lymphoma (ATLL) often involves the skin. Cases with skin lesions without either leukemic nor lymph node involvement have been categorized into a cutaneous type. While the clinical manifestations of the cutaneous-type ATLL are variable, including multiple papules, nodules, plaques, or erythroderma...

journal_title：Journal of the American Academy of Dermatology

authors： Shimizu S,Yasui C,Koizumi K,Ikeda H,Tsuchiya K

更新日期：2007-11-01 00:00:00

abstract：:Dermatologists frequently are consulted by a pregnant patient or a woman of childbearing age who desires acne therapy. Because there are no published studies in which women took acne medications throughout pregnancy, information about safety must be obtained indirectly from studies in which the agents were taken for a...

journal_title：Journal of the American Academy of Dermatology

authors： Rothman KF,Pochi PE

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:It is unsettled whether small plaque parapsoriasis (SPP) represents an inflammatory dermatosis or has a potential to transform into mycosis fungoides (MF) or is, in fact, MF. The literature contains no fully documented example of progression of SPP into MF. OBJECTIVE:The purpose of our study was to present ...

journal_title：Journal of the American Academy of Dermatology

authors： Belousova IE,Vanecek T,Samtsov AV,Michal M,Kazakov DV

更新日期：2008-09-01 00:00:00

abstract：:Lymphocytoma cutis characteristically appears as persistent reddish purple papules, nodules, or plaques. Response to treatment is variable and recurrences are common. We report the use of the argon laser as a modality that improved cosmetic appearance and alleviated symptoms of lymphocytoma cutis but that failed to pr...

journal_title：Journal of the American Academy of Dermatology

authors： Wheeland RG,Kantor GR,Bailin PL,Bergfeld WF

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Hidradenitis suppurativa (HS) is a chronic inflammatory disease involving intertriginous skin. Previous epidemiologic studies have been limited by small sample size. OBJECTIVE:We sought to describe the prevalence and comorbidities of HS in a large patient care database. METHODS:In this retrospective case-c...

journal_title：Journal of the American Academy of Dermatology

authors： Shlyankevich J,Chen AJ,Kim GE,Kimball AB

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Although cutaneous Crohn's disease is well recognized in adults, in children it is extremely rare. OBJECTIVE:Our purpose was to describe five children with cutaneous Crohn's disease and to review the literature. METHODS:The medical records of five children with cutaneous Crohn's disease were retrospectivel...

journal_title：Journal of the American Academy of Dermatology

authors： Ploysangam T,Heubi JE,Eisen D,Balistreri WF,Lucky AW

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Onychomatricoma (OM) is a rare benign tumor of the nail matrix in which genome-wide analyses have never been performed. It is clinically characterized by an increased transversal curvature of the nail plate, a longitudinal yellowish discoloration, and splinter hemorrhages. Once the nail plate has been remove...

journal_title：Journal of the American Academy of Dermatology

authors： Cañueto J,Santos-Briz Á,García JL,Robledo C,Unamuno P

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Pachyonychia congenita (PC) is a group of autosomal dominant keratinizing disorders caused by a mutation in one of 4 keratin genes. Previous classification schemes have relied on data from case series and case reports. Most patients in these reports were not genetically tested for PC. OBJECTIVE:We sought to...

journal_title：Journal of the American Academy of Dermatology

authors： Eliason MJ,Leachman SA,Feng BJ,Schwartz ME,Hansen CD

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:The Food and Drug Administration (FDA) has received reports of depression and suicide in patients treated with isotretinoin. OBJECTIVE:Our purpose was to provide the number and describe the cases of depression and suicide reported to the FDA in US patients treated with isotretinoin and to consider the natur...

journal_title：Journal of the American Academy of Dermatology

authors： Wysowski DK,Pitts M,Beitz J

更新日期：2001-10-01 00:00:00

abstract：:Malignant myxoid melanoma (MMM) is a rarely reported variant of malignant melanoma, which can often be confused with other mucin-containing neoplasms. A retrospective study of 3 cases of MMM and a review of the English-language literature was performed. MMM affects an older population and is frequently misdiagnosed. T...

journal_title：Journal of the American Academy of Dermatology

authors： Patel P,Levin K,Waltz K,Helm KF

更新日期：2002-02-01 00:00:00

abstract：:Cutaneous multilobated T-cell lymphoma is an uncommon variant of skin-based peripheral T-cell lymphoma typically characterized by cutaneous nodules in elderly patients and a chronic clinical course. We report a case of the disease that led to the patient's death within 2 years after onset. This disease may be associat...

journal_title：Journal of the American Academy of Dermatology

authors： Goldman BD,Bari M,Kantor GR,Kadin ME,Micaily B,Vonderheid EC

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Significant unmet need exists for long-term treatment of moderate to severe atopic dermatitis (AD). OBJECTIVE:To assess the long-term safety and efficacy of dupilumab in patients with AD. METHODS:This ongoing, multicenter, open-label extension study (NCT01949311) evaluated long-term dupilumab treatment in ...

journal_title：Journal of the American Academy of Dermatology

authors： Deleuran M,Thaçi D,Beck LA,de Bruin-Weller M,Blauvelt A,Forman S,Bissonnette R,Reich K,Soong W,Hussain I,Foley P,Hide M,Bouaziz JD,Gelfand JM,Sher L,Schuttelaar MLA,Wang C,Chen Z,Akinlade B,Gadkari A,Eckert L,Da

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:There are multiple therapeutic options for the treatment of moderate to severe psoriasis. The process of choosing among potential treatment options requires both the physician and the patient to weigh the benefits of individual modalities against their potential risks. Traditional systemic therapies for psor...

journal_title：Journal of the American Academy of Dermatology

authors： Patel RV,Clark LN,Lebwohl M,Weinberg JM

更新日期：2009-06-01 00:00:00

abstract：:We report a case of amelanotic melanoma that was clinically and dermoscopically featureless; it was repeatedly missed during examination at a pigmented lesion clinic. Dermoscopy evidenced a peculiar vascular pattern, and only the adoption of a specific diagnostic algorithm including the atypical vascular pattern among...

journal_title：Journal of the American Academy of Dermatology

authors： Carli P,Massi D,de Giorgi V,Giannotti B

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:A narrow-band UVB lamp (Philips TL 01) emitting a peak of approximately 311 nm was developed to improve the phototherapy for psoriasis. Only a few studies have been performed with promising results. OBJECTIVE:The therapeutic efficacy of the Philips TL 01 lamp in a new 100 W version was compared with convent...

journal_title：Journal of the American Academy of Dermatology

authors： Storbeck K,Hölzle E,Schürer N,Lehmann P,Plewig G

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Mohs micrographic surgery (MMS) is an effective treatment for skin cancer. Until recently, it has been difficult to determine the percentage of skin cancers best treated with MMS. The appropriate-use criteria represents an opportunity to more accurately estimate this number. OBJECTIVE:We sought to apply the...

journal_title：Journal of the American Academy of Dermatology

authors： Blechman AB,Patterson JW,Russell MA

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Griseofulvin has been used in the treatment of toenail onychomycosis with limited success. Evidence suggests that terbinafine may be more effective. OBJECTIVE:In a double-blind, parallel-group study we compared 250 mg/day terbinafine for 16 weeks with 500 mg/day griseofulvin for 52 weeks (or for shorter per...

journal_title：Journal of the American Academy of Dermatology

authors： Faergemann J,Anderson C,Hersle K,Hradil E,Nordin P,Kaaman T,Molin L,Pettersson A

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Vulvo-cervico-vaginal involvement has rarely been reported in pemphigus vulgaris (PV) and has not been reported in pemphigus foliaceus (PF). OBJECTIVES:We sought to evaluate genital lesions and Papanicolaou (Pap) smears in female patients with PV and PF. METHODS:This prospective study includes all consecut...

journal_title：Journal of the American Academy of Dermatology

authors： Fairbanks Barbosa ND,de Aguiar LM,Maruta CW,Aoki V,Sotto MN,Labinas GH,Perigo AM,Santi CG

更新日期：2012-09-01 00:00:00