Clinical significance of cultures collected from fine-needle aspiration biopsy.


:The rate of positive cultures in fine-needle aspiration biopsy (FNAB) specimens is evaluated, and the value of submitting FNAB culture is assessed. Review of 3,300 FNAB specimens from 2,416 patients were tabulated for culture results, when obtained from the FNAB material. For positive culture results, clinical impact was assessed. Of 3,300 FNAB specimens and 2,416 patients, 185 had cultures performed (6% of specimens, 8% of patients). Of the 185 cultured specimens, 63 (34%) were positive and 122 (66%) were negative. Of the 63 positive cultures, 23 (12% of all FNAB cultures) had a significant impact on patient care. In our institution the FNA culture rate is 6%. When cases with clinical or microscopic suspicion of infection are cultured, 34% are positive for aerobic or anaerobic bacteria, mycobacteria or fungus. Culture in FNA specimens is a useful adjunct to diagnosis and impacts care in 12% of patients cultured at FNAB. This method can be used to triage patients with suspected infectious diseases and can aid in managing patients who may have recurrent infections.


Diagn Cytopathol


Diagnostic cytopathology


Granville LA,Laucirica R,Verstovsek G




Has Abstract


2008-02-01 00:00:00












  • Retroperitoneal lymph node aspiration biopsy in staging of pelvic cancer: a cytological study of 228 consecutive cases.

    abstract::Knowledge of the status of the pelvic lymph nodes is important for accurate staging and adequate treatment of patients with genitourinary tract cancer (bladder and prostatic carcinoma, testicular tumors, and uterine carcinoma). A total of 228 consecutive patients underwent preoperative evaluation of the lymph node sta...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Cochand-Priollet B,Roger B,Boccon-Gibod I,Ferrand J,Faure B,Blery M

    更新日期:1987-06-01 00:00:00

  • The Bethesda System for Reporting Thyroid Cytology (TBSRTC): From look-backs to look-ahead.

    abstract::The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) was formalized in October 2007 by experts in thyroidology at the National Institute of Health in Bethesda, Maryland. The first edition of the TBSRTC book was published in 2010 and the second edition in 2018. The TBSRTC is widely employed in cytology prac...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Baloch Z,LiVolsi VA

    更新日期:2020-10-01 00:00:00

  • Synovial sarcoma metastatic to the parotid gland: A possible pitfall in salivary gland fine needle aspiration cytology. Report of a case with immunocytochemical and fluorescence in situ hybridization findings.

    abstract::We report one case of metastatic synovial sarcoma (SS) to the parotid gland in a 93-year-old male. The patient had undergone upper left pulmonary lobectomy with mediastinal lymphadenectomy for SS of the lung 5 years before. The cytopathologic presentation and the immunocytochemical findings on the FNA sample were sugg...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Fulciniti F,Barizzi J,Martin V,Tarallo V,Ermanni S

    更新日期:2017-09-01 00:00:00

  • Nodular fasciitis: spontaneous resolution following diagnosis by fine-needle aspiration.

    abstract::Nodular fasciitis can be histologically mistaken for a sarcoma. Typical cases are less than 5 cm and enlarge rapidly over days or weeks before diagnosis. The natural history of nodular fasciitis is unknown, since the diagnosis is usually based on excised lesions. Fine-needle aspiration of nodular fasciitis has been de...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Stanley MW,Skoog L,Tani EM,Horwitz CA

    更新日期:1993-01-01 00:00:00

  • Fine-needle aspiration of cystic nephroma (multilocular cyst of the kidney).

    abstract::Cystic nephromas are rare tumors of the kidney most commonly affecting boys or adult females. The fine-needle aspiration cytomorphology has not yet been described. A renal cystic mass in a 56 year old female was aspirated under ultrasound guidance. Papanicolaou stained smears of the cyst fluid revealed markedly atypic...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Clark SP,Kung IT,Tang SK

    更新日期:1992-01-01 00:00:00

  • Fine-needle-aspiration cytology of a proximal type epithelioid sarcoma: A case report.

    abstract::Epithelioid sarcoma is a rare mesenchymal neoplasm, with an as yet unidentified cell of origin. Two subtypes of epithelioid sarcoma, distal/classic and proximal/large cell type, are recognized in the literature; with the proximal-type having a lower incidence amongst the two. Here, we present a case of proximal-type e...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Pendse AA,Dodd LG

    更新日期:2015-10-01 00:00:00

  • Unusual presentation of granulocytic sarcoma in the breast: a case report and review of the literature.

    abstract::This is a case of granulocytic sarcoma presenting as bilateral breast masses in a 40-yr-old woman with concurrent unsuspected chronic myeloid leukemia diagnosed by fine-needle aspiration. The granulocytic differentiation was recognized on Diff-Quik-stained cytology smears and confirmed rapidly on flow cytometry on the...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章,评审


    authors: Ngu IW,Sinclair EC,Greenaway S,Greenberg ML

    更新日期:2001-01-01 00:00:00

  • Pregnancy-associated anaplastic large-cell lymphoma of the breast: a rare mimic of ductal carcinoma.

    abstract::Anaplastic large-cell lymphoma (ALCL) is a rare T-cell lymphoma typically seen in children and young adults. It has been described in numerous sites; however, the breast is one of the least common locations. We herein report a case of ALCL arising in the breast of a 36-yr-old pregnant woman. To our knowledge this is t...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Iyengar P,Reid-Nicholson M,Moreira AL

    更新日期:2006-04-01 00:00:00

  • Epidermal growth factor receptor and Kras gene expression: reliability of mutational analysis on cytological samples.

    abstract::Epidermal growth factor receptor (EGFR) and Kras gene mutations are crucial for discriminating patients responsive to anti-EGFR drugs in non-small cell lung cancer (NSCLC) and colorectal cancer (CRC), respectively. The majority of NSCLCs come to clinical attention at an advanced stage when surgery is no longer recomme...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Bozzetti C,Negri FV,Azzoni C,Naldi N,Nizzoli R,Bortesi B,Zobbi V,Bottarelli L,Tiseo M,Silini EM,Ardizzoni A

    更新日期:2013-07-01 00:00:00

  • Cytomorphology and Clinicopathologic Correlation of the Recurrent and Metastatic Adult Granulosa Cell Tumor of the Ovary: A Retrospective Review.

    abstract::Granulosa cell tumors (GCT) of the ovary are low grade tumor with a potential ability of late pelvic recurrences and distant metastases. However, there is sparse literature on the cytopathologic features of metastatic granulosa cell tumors (MGCT). Between 2000 and 2014, eight cases of MGCT were diagnosed by FNA. Clini...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Harbhajanka A,Bitterman P,Reddy VB,Park JW,Gattuso P

    更新日期:2016-12-01 00:00:00

  • Extranodal NK/T-cell lymphoma, nasal type of the uterine cervix: A case report.

    abstract::We report a rare case of extranodal NK/T-cell lymphoma, nasal type of the uterine cervix that showed cytologic features mimicking cervical cancer. A 65-year-old woman presented with vaginal bleeding. Gynecological examination revealed a bulky tumor of the cervix. A conventional Papanicolaou-stained cervical smear show...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Omori M,Oishi N,Nakazawa T,Nakazawa K,Mitsumori T,Yuminamochi T,Kirito K,Hirata S

    更新日期:2016-05-01 00:00:00

  • Cytologic diagnosis of true thymic hyperplasia by combined radiologic imaging and aspiration cytology: a case report including flow cytometric analysis.

    abstract::True thymic hyperplasia (TH) is an age-dependent increase in size and weight of the thymus gland, which by definition maintains a normal histologic architecture. TH can mimic other important diseases, including lymphofollicular hyperplasia, thymoma, lymphoma, and germ-cell tumors. Traditionally, separating these entit...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Hoerl HD,Wojtowycz M,Gallagher HA,Kurtycz DF

    更新日期:2000-12-01 00:00:00

  • The role of routine outpatient cytological screening for early detection of carcinoma of the cervix in India.

    abstract::Cytological evaluation of cervical smears has been carried out in 4,338 women attending the Gynecology and Obstetrics Department and Family Planning Clinic of Queen Mary's Hospital, Lucknow, India, since April 1971. The incidence of cervical dysplasia was found to be 4.6% (205 out of 4,338) in the series, while malign...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Engineer AD,Misra JS

    更新日期:1987-03-01 00:00:00

  • Cytologic features of meningiomas on crush preparations: a review.

    abstract::Meningiomas are rarely subjected to aspiration, however, since they may occur outside the central nervous system, it is important to recognize their cytologic features. The goal of this study was to examine the cytologic features of meningiomas in crush preparations and cytologic imprints prepared at the time of froze...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Siddiqui MT,Mahon BM,Cochran E,Gattuso P

    更新日期:2008-04-01 00:00:00

  • Axillary lymph node metastasis: Fine-needle aspiration biopsy sensitivity as a function of node size, percent replacement of lymph node by tumor and tumor deposit size.

    abstract:BACKGROUND:Fine-needle aspiration (FNA) is commonly used to investigate lymphadenopathy of suspected metastatic origin. While diagnostic accuracy of FNA for lymph node disease is well described, the relationship between node size, percent tumor replacement, and size of metastatic deposit with diagnostic accuracy is les...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Layfield LJ,Zhang T,Esebua M,Schmidt R

    更新日期:2021-02-01 00:00:00

  • Characteristic cytologic findings of epithelioid hemangioendothelioma: A case report and review of literature.

    abstract::Epithelioid hemangioendothelioma is a rare vascular neoplasm of low-grade malignancy. We observed a case of epithelioid hemangioendothelioma arising in a cervical lymph node. Fine needle aspiration cytology showed several characteristic findings of epithelioid hemangioendothelioma, that is, nuclear inclusion bodies, n...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Kurisu Y,Tsuji M,Kuwabara H,Shibayama Y

    更新日期:2011-02-01 00:00:00

  • Pitfalls in the diagnosis of adult rhabdomyoma by fine needle aspiration: report of a case and a brief literature review.

    abstract::Fine needle aspiration (FNA) is a valuable, noninvasive, commonly used technique in the diagnoses of head and neck tumors. Adult rhabdomyoma is a rare benign tumor of striate muscle tissue usually located in the head and neck region. Cytomorphologically, the tumor cells have eosinophilic finely granular cytoplasm, whi...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章,评审


    authors: Jin B,Saleh H

    更新日期:2009-07-01 00:00:00

  • Granulocyte colony-stimulating factor-producing small-cell carcinoma of the uterine cervix: report of a case.

    abstract::A case of granulocyte colony-stimulating factor (G-CSF)-producing small-cell carcinoma of the uterine cervix is described. In a 70-yr-old woman, clusters of small cells with hyperchromatic nuclei at a high nuclear/cytoplasmic ratio were detected cytologically in the cervix. These clusters were diagnosed as a small-cel...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Watanabe A,Wachi T,Omi H,Nishii H,Ochiai K,Tanaka T,Endo Y

    更新日期:2000-10-01 00:00:00

  • Needle aspiration cytology, immunocytochemistry, and electron microscopic study of unusual pancreatic carcinoma with pleomorphic giant cells.

    abstract::Needle aspiration cytology, immunocytochemistry, and electron-microscopic findings are presented in three cases of an unusual pancreatic carcinoma in which pleomorphic giant cells formed an integral part of the tumour. All three patients were elderly males (age range 66-83 years) and had pancreatic masses. Notable cyt...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Gupta RK,Wakefield SJ

    更新日期:1992-01-01 00:00:00

  • Adenoviral cytopathic changes in pleural fluid: A unique cytological presentation mimicking malignancy.

    abstract::Adenoviruses are emerging as important viral pathogens in immunocompromised patients due to immunodeficiency diseases and recently hematopoietic stem cell and solid organ transplant recipients, impacting morbidity and even mortality. Immunocompromised children are prone to respiratory infection, due to alterations in ...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Harbhajanka A,Michael CW

    更新日期:2020-11-16 00:00:00

  • Reflex high-risk human papilloma virus DNA test is useful in the triage of women with atypical squamous cells cannot exclude high-grade squamous intraepithelial lesion.

    abstract::This study is aimed to investigate the role of reflex high-risk human papilloma virus (HPV) DNA testing as an alternative triage method to colposcopy for women with atypical squamous cells cannot exclude high-grade squamous intraepithelial lesion (ASC-H) on Papanicolaou (Pap) tests. Reflex HPV DNA testing using Hybrid...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Wu HH,Allen SL,Kirkpatrick JL,Elsheikh TM

    更新日期:2006-10-01 00:00:00

  • Fine-needle aspiration cytologic features of pseudovascular adenoid squamous-cell carcinoma of the lung.

    abstract::Pseudovascular adenoid squamous-cell carcinoma (PASCC) is an epithelial malignancy with spindle-cell features that can mimic vascular neoplasms, particularly angiosarcoma, in its morphologic characteristics. There have been only a few surgical pathology reports of PASCC arising in the lung, skin, and breast. We descri...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Smith AR,Raab SS,Landreneau RJ,Silverman JF

    更新日期:1999-10-01 00:00:00

  • Use of a novel marker, calponin, for myoepithelial cells in fine-needle aspirates of papillary breast lesions.

    abstract::Benign and malignant papillary lesions of the breast (PBL) can be difficult to distinguish in fine-needle aspirates (FNA). This study evaluates the use of smooth muscle actin (SMA) and a new smooth muscle-specific protein, calponin, for identifying myoepithelial cells (MEC) by immunohistochemical methods in paraffin-e...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Mosunjac MB,Lewis MM,Lawson D,Cohen C

    更新日期:2000-09-01 00:00:00

  • Osteitis fibrosa cystica (brown tumor) of the spine with cord compression: report of a case with needle aspiration biopsy findings.

    abstract::A case of osteitis fibrosa cystica or brown tumor of bone in a patient presenting with acute spinal cord compression that was suggested initially by needle aspiration biopsy of the spine is described. Following the aspiration biopsy, excision of vertebral lesions, cord decompression, and spinal fusion were successfull...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Kashkari S,Kelly TR,Bethem D,Pepe RG

    更新日期:1990-01-01 00:00:00

  • Prevalence of epithelial abnormalities and high-risk human papilloma virus in cervicovaginal Pap smears of population subgroups as a guide toward evidence-based best practice.

    abstract:BACKGROUND:The 2012 American Society for Colposcopy and Cervical Pathology Consensus Guidelines provide information for managing abnormal cervical cancer screening tests and cancer precursors. According to these guidelines for Pap smear diagnosis of Atypical squamous cells of undetermined significance, reflex high risk...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Siddiqi A,Webb F,Smotherman C,Shuja S,Mubeen A,Lai K

    更新日期:2019-07-01 00:00:00

  • Fine-needle aspiration cytology of hepatic leiomyosarcoma.

    abstract::Hepatic leiomyosarcoma is a rare malignancy to involve the liver, occurring as a primary liver sarcoma in patients without an underlying medical disorder, as a metastatic malignancy, and with increasing incidence, as a primary tumor in AIDS patients. A series of hepatic leiomyosarcomas diagnosed by FNA biopsy, includi...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Smith MB,Silverman JF,Raab SS,Towell BD,Geisinger KR

    更新日期:1994-12-01 00:00:00

  • Endoscopic ultrasound-guided fine-needle aspiration diagnosis of Merkel cell carcinoma metastatic to the pancreas.

    abstract::Merkel cell carcinoma (MCC) is a rare and highly aggressive primary neuroendocrine carcinoma of the skin with a high propensity for local, regional, and distant spread. Distant metastasis of MCC to the pancreas is uncommonly seen and may impose a diagnostic challenge cytologically. Here we report a case of MCC with pa...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Bernstein J,Adeniran AJ,Cai G,Theoharis CG,Ustun B,Beckman D,Aslanian HR,Harigopal M

    更新日期:2014-03-01 00:00:00

  • Improving ROSE: Discrepant touch preparation and histology findings in cytology of renal masses: A 10-year retrospective review.

    abstract:BACKGROUND:The number of "renal incidentalomas" is on the rise due to increasing use of radiologic studies. Image-guided core needle biopsies (CNB) with touch preparations are performed to guide specimen collection and triage of sample for additional studies. Results allow the clinical team to make appropriate treatmen...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Shachner TR,Nodit L,Hubbard E,Van Meter S

    更新日期:2019-10-01 00:00:00

  • American Society of Cytopathology workload recommendations for automated Pap test screening: developed by the productivity and quality assurance in the era of automated screening task force.

    abstract::Based on current literature and the best available research to date, the current FDA workload limits for automated image-assisted screening, including the ThinPrep Imaging System and the FocalPoint GS, of 100 slides/day (imaged only slides counted as 0.5) are extremely high and may be associated with significant reduc...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章,实务指引


    authors: Elsheikh TM,Austin RM,Chhieng DF,Miller FS,Moriarty AT,Renshaw AA,American Society of Cytopathology.

    更新日期:2013-02-01 00:00:00

  • Fine-needle aspiration of a pleomorphic lipoma of the head and neck: a case report.

    abstract::Pleomorphic lipoma is a rare soft-tissue tumor, most commonly seen in the head and neck regions of middle-aged men. Fine-needle aspiration (FNA) of these lesions can present a diagnostic challenge. Its large, hyperchromatic cells and multinucleated forms (floret cells) can easily be mistaken for a malignancy. A patien...

    journal_title:Diagnostic cytopathology

    pub_type: 杂志文章


    authors: Yong M,Raza AS,Greaves TS,Cobb CJ

    更新日期:2005-02-01 00:00:00