Morphologic and physiologic response of lungs to steroid and cigarette smoke: an animal model.

Abstract:

:The combined effects of cigarette smoke inhalation and hydrocortisone acetate (HCA) treatment induce prominent abnormalities in lungs of C57BL/6 male mice. These abnormalities include (1) a marked reduction of pulmonary macrophage population which is normally elevated by smoke inhalation, (2) an accumulation of surfactant and flocculent material in alveoli, (3) a decrease in alveolar space surrounded by normal septal tissue, and (4) an increase in hypertrophied alveolar parenchyma. Concomitant with altered lung morphology, lung volume and gas diffusing capacity were significantly compromised in animals subjected to smoke exposure and steroid treatment. It was found that smoke inhalation or HCA administration alone had no ill effects on the animals. The data presented indicate that manifestation of pathologic conditions resembling pulmonary fibrosis and pulmonary alveolar proteinosis is a result of cigarette smoke-drug interaction. The information reported provides a basis for an animal model which might be applicable to assessment of factors related to smoke inhalation and development of pulmonary disorders.

journal_name

Environ Res

journal_title

Environmental research

authors

Matulionis DH,Kimmel E,Diamond L

doi

10.1016/0013-9351(85)90026-x

subject

Has Abstract

pub_date

1985-04-01 00:00:00

pages

298-313

issue

2

eissn

0013-9351

issn

1096-0953

pii

0013-9351(85)90026-X

journal_volume

36

pub_type

杂志文章
  • Oxidative stress and related gene expression effects of cyfluthrin in human neuroblastoma SH-SY5Y cells: Protective effect of melatonin.

    abstract::This study was designed to assess oxidative stress induction in human neuroblastoma SH-SY5Y cells in response to cyfluthrin exposure. Cell viability MTT assay was carried out to assess cyfluthrin cytotoxicity; IC30 and IC50 values for cyfluthrin were calculated to be 4.81 ± 0.92 μM and 19.39 ± 3.44 μM, respectively. C...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2019.108579

    authors: Martínez MA,Rodríguez JL,Lopez-Torres B,Martínez M,Martínez-Larrañaga MR,Anadón A,Ares I

    更新日期:2019-10-01 00:00:00

  • Presence of lead in paint of toys sold in stores of the formal market of Bogotá, Colombia.

    abstract::Lead (Pb) is a non-essential metal. Exposure to lead has been associated with adverse health effects in both children and adults. Lead content in paint used in toys or children's products has been identified as both a potential and preventable source of childhood lead exposure. Twenty-four stores located in Bogotá (Co...

    journal_title:Environmental research

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.envres.2013.11.005

    authors: Mateus-García A,Ramos-Bonilla JP

    更新日期:2014-01-01 00:00:00

  • Effects of polychlorobiphenyls, polybromodiphenylethers, organochlorine pesticides and their metabolites on vitamin A status in lactating grey seals.

    abstract::Polychlorobiphenyls (PCBs), polybromodiphenylethers (PBDEs) and organochlorine pesticides (OCPs), such as dichlorodiphenyltrichloroethane (DDT) and hexachlorobenzene (HCB), are considered as endocrine disruptors in laboratory and wild animals. This study investigated whether these compounds and their hydroxylated meta...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2012.09.004

    authors: Vanden Berghe M,Weijs L,Habran S,Das K,Bugli C,Pillet S,Rees JF,Pomeroy P,Covaci A,Debier C

    更新日期:2013-01-01 00:00:00

  • Effects of ambient temperature and precipitation on the risk of dengue fever: A systematic review and updated meta-analysis.

    abstract:OBJECTIVES:We systematically reviewed the published studies on the relationship between dengue fever and meteorological factors and applied a meta-analysis to explore the effects of ambient temperature and precipitation on dengue fever. METHODS:We completed the literature search by the end of September 1st, 2019 using...

    journal_title:Environmental research

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.envres.2020.110043

    authors: Li Y,Dou Q,Lu Y,Xiang H,Yu X,Liu S

    更新日期:2020-12-01 00:00:00

  • Sexual differences in the distribution and retention of organic and inorganic mercury in methyl mercury-treated rats.

    abstract::At 56 days of age, male and female Long-Evans rats received 1 mumole of 203Hg-labeled methyl mercuric chloride per kilogram sc and total, organic, and inorganic mercury contents and concentrations in tissues were determined for up to 98 days postdosing. Whole body clearance of mercury was faster in females than in mal...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/s0013-9351(86)80184-0

    authors: Thomas DJ,Fisher HL,Sumler MR,Marcus AH,Mushak P,Hall LL

    更新日期:1986-10-01 00:00:00

  • Blood cadmium levels are associated with a decline in lung function in males.

    abstract:BACKGROUND:Cadmium exposure was found to cause a decline in lung function among the general population, but these findings were limited to smokers and gender differences were not explored. OBJECTIVES:To examine the relationship between cadmium and chronic obstructive pulmonary disease (COPD) according to gender and sm...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2014.04.008

    authors: Oh CM,Oh IH,Lee JK,Park YH,Choe BK,Yoon TY,Choi JM

    更新日期:2014-07-01 00:00:00

  • Mercury in canned tuna: white versus light and temporal variation.

    abstract::There are abundant data and advisories for mercury levels in wild fish, but far fewer for commercial fish that compose a large majority of the fish most people eat. Until recently, relatively little attention has been devoted to examining mercury in canned tuna, despite its great importance in human diets. There is su...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2003.12.001

    authors: Burger J,Gochfeld M

    更新日期:2004-11-01 00:00:00

  • Phytobeds with Fimbristylis dichotoma and Ammannia baccifera for treatment of real textile effluent: An in situ treatment, anatomical studies and toxicity evaluation.

    abstract::Fimbristylis dichotoma, Ammannia baccifera and their co-plantation consortium FA independently degraded Methyl Orange, simulated dye mixture and real textile effluent. Wild plants of F. dichotoma and A. baccifera with equal biomass showed 91% and 89% decolorization of Methyl Orange within 60h at a concentration of 50p...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2017.09.009

    authors: Kadam SK,Chandanshive VV,Rane NR,Patil SM,Gholave AR,Khandare RV,Bhosale AR,Jeon BH,Govindwar SP

    更新日期:2018-01-01 00:00:00

  • Effects of prenatal exposure to silver nanoparticles on spatial cognition and hippocampal neurodevelopment in rats.

    abstract:BACKGROUND:Silver nanoparticles (Ag-NPs) are among the most commonly used nanomaterials and may be exposed to human and ecosystem. Prior in vitro study showed that Ag-NPs compromised neurodevelopment of PC12 cells. This study aims to investigate the effect of prenatal exposure to Ag-NPs on spatial cognition and hippoca...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2015.01.022

    authors: Wu J,Yu C,Tan Y,Hou Z,Li M,Shao F,Lu X

    更新日期:2015-04-01 00:00:00

  • Insights from an international stakeholder consultation to identify informational needs related to seafood safety.

    abstract::Food safety assessment and communication have a strong importance in reducing human health risks related to food consumption. The research carried out within the ECsafeSEAFOOD project aims to assess seafood safety issues, mainly related to non-regulated priority environmental contaminants, and to evaluate their impact...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2015.06.038

    authors: Tediosi A,Fait G,Jacobs S,Verbeke W,Álvarez-Muñoz D,Diogene J,Reuver M,Marques A,Capri E

    更新日期:2015-11-01 00:00:00

  • Metal mixtures and kidney function: An application of machine learning to NHANES data.

    abstract:BACKGROUND:Exposure to heavy metals may increase risk of kidney disease, but most studies have examined individual metals or two-way interactions. There is increasing recognition of the importance of studying exposure to metal mixtures and health outcomes. OBJECTIVES:We used Bayesian kernel machine regression (BKMR) t...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2020.110126

    authors: Luo J,Hendryx M

    更新日期:2020-12-01 00:00:00

  • Microplastics in three typical benthic species from the Arctic: Occurrence, characteristics, sources, and environmental implications.

    abstract::Microplastics (MPs) in the Arctic have raised increasing concern, but knowledge on MP contamination in benthic organisms from Arctic shelf regions, e.g., the Chukchi Sea is still limited. Therefore, the present study investigated the occurrence, characteristics, sources, and environmental implications of MPs in the th...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2020.110326

    authors: Fang C,Zheng R,Hong F,Jiang Y,Chen J,Lin H,Lin L,Lei R,Bailey C,Bo J

    更新日期:2021-01-01 00:00:00

  • Association between exposure to air pollution and prefrontal cortical volume in adults: A cross-sectional study from the UK biobank.

    abstract::Associated with numerous cognitive and behavioral functions and with several diseases, the prefrontal cortex is vulnerable to environmental insult. Among other factors, toxins in air pollution have been associated with damage to the prefrontal cortex in children and older adults. We used data from the UK Biobank to as...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2020.109365

    authors: Gale SD,Erickson LD,Anderson JE,Brown BL,Hedges DW

    更新日期:2020-06-01 00:00:00

  • The aspect ratio of gold nanorods as a cytotoxicity factor on Raphidocelis subcaptata.

    abstract::Gold nanorods (AuNRs) are promising nanoscale materials for several technological and biomedical applications. The physicochemical properties of AuNRs, including size, shape and surface features, are crucial factors affecting their cytotoxicity. In this study, we investigated the effects of different aspect ratios of ...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2020.110133

    authors: Nogueira PFM,Marangoni VS,Zucolotto V

    更新日期:2020-12-01 00:00:00

  • Chemical exposure reduction: Factors impacting on South African herbicide sprayers' personal protective equipment compliance and high risk work practices.

    abstract::The high exposure risks of workers to herbicides in low- and middle-income countries is an important public health concern because of the potential resulting negative impacts on workers' health. This study investigated workers' personal protective equipment (PPE) compliance as a risk mitigation measure; particularly w...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2015.05.028

    authors: Andrade-Rivas F,Rother HA

    更新日期:2015-10-01 00:00:00

  • Changes in the lead isotopic composition of blood, diet and air in Australia over a decade: globalization and implications for future isotopic studies.

    abstract::Source apportionment in biological or environmental samples using the lead isotope method, where there are diverse sources of lead, relies on a significant difference between the isotopic composition in the target media and the sources. Because of the unique isotopic composition of Australian lead, source apportionmen...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2005.03.006

    authors: Gulson B,Mizon K,Korsch M,Taylor A

    更新日期:2006-01-01 00:00:00

  • Global impact of ciguatoxins and ciguatera fish poisoning on fish, fisheries and consumers.

    abstract::Ciguatera fish poisoning (CFP) is one of the most devastating food-borne illnesses caused by fish consumption. Ciguatoxins (CTXs) are potent neurotoxins synthesized by the benthic microalgae Gambierdiscus spp. and Fukuyoa spp. that are transmitted to fish by grazing and predation. Despite the high incidence of CFP, af...

    journal_title:Environmental research

    pub_type: 杂志文章,评审

    doi:10.1016/j.envres.2020.109111

    authors: Soliño L,Costa PR

    更新日期:2020-03-01 00:00:00

  • Evaluation of exposure to road traffic noise: Effects of microphone height and urban configuration.

    abstract::Noise pollution is a major environmental problem due to its impact on human health and implications for other spheres of society. Since road traffic is the main source of noise pollution, the use of measurement methodologies to accurately determine the environmental noise levels to which the façades of buildings in ci...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2020.110055

    authors: Montes González D,Barrigón Morillas JM,Rey Gozalo G,Godinho L

    更新日期:2020-12-01 00:00:00

  • Lead in new paints in Nepal.

    abstract::Samples from 75 paint products made by 21 domestic and foreign manufacturers were purchased from retail stores in five major cities in Nepal and tested for lead content. Information provided on product labels were noted. Samples were selected to be representative of the large number of brands and colors available in r...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2014.03.036

    authors: Gottesfeld P,Pokhrel D,Pokhrel AK

    更新日期:2014-07-01 00:00:00

  • A comparison of the effects of exposure of baboons to crocidolite and fibrous-glass dusts.

    abstract::Epidemiological studies have not revealed any significant health hazards from exposure to fibrous glass and animal experiments have been inconclusive. Baboons exposed to a fibrous-glass dust cloud with size features similar to those of crocidolite asbestos developed focal peribronchiolar fibrosis with scant ferruginou...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/0013-9351(83)90117-2

    authors: Goldstein B,Rendall RE,Webster I

    更新日期:1983-12-01 00:00:00

  • In vivo and in vitro dermal penetration of 2,4,5,2',4',5'-hexachlorobiphenyl in young and adult rats.

    abstract::Penetration of 2,4,5,2',4',5'-[14C]hexachlorobiphenyl (HCB) through skin of young (33 days) and adult (82 days) female Fischer 344 rats was determined in vivo and by two in vitro methods. In vivo dermal penetration at 120 hr was 45% in young and 43% in adults. At 72 hr in vivo dermal penetration was 35% in young and 2...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/s0013-9351(89)80053-2

    authors: Fisher HL,Shah PV,Sumler MR,Hall LL

    更新日期:1989-10-01 00:00:00

  • Effect of body length, trophic position and habitat use on mercury concentrations of sharks from contrasted ecosystems in the southwestern Indian Ocean.

    abstract::The non-essential metal mercury (Hg) can have deleterious effects on health of organisms, and tends to bioaccumulate with age in long-lived organisms and to biomagnify along food webs. Because elasmobranchs are fished for human consumption and their Hg levels are frequently above the maximum Hg concentration recommend...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2018.11.024

    authors: Le Bourg B,Kiszka JJ,Bustamante P,Heithaus MR,Jaquemet S,Humber F

    更新日期:2019-02-01 00:00:00

  • Results of magnetic resonance imaging in long-term manganese dioxide-exposed workers.

    abstract::Within a cross-sectional study, the neurotoxic effects of occupational exposure to manganese were examined. From a group of 90 (58 male and 32 female) workers, 11 men with long-term and high exposure to manganese dioxide (MnO2) dust were defined as exposed workers. Eleven age-matched workers of similar socioeconomic s...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1006/enrs.2000.4068

    authors: Dietz MC,Ihrig A,Wrazidlo W,Bader M,Jansen O,Triebig G

    更新日期:2001-01-01 00:00:00

  • Seasonal variation in airborne endotoxin levels in indoor environments with different micro-environmental factors in Seoul, South Korea.

    abstract::This study evaluated the variation over a year in airborne endotoxin levels in the indoor environment of five university laboratories in Seoul, South Korea, and examined the micro-environmental factors that influenced endotoxin levels. These included temperature, relative humidity, CO2, CO, illumination, and wind velo...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2015.11.025

    authors: Hwang SH,Park DJ,Park WM,Park DU,Ahn JK,Yoon CS

    更新日期:2016-02-01 00:00:00

  • Bifunctional iron-modified graphitic carbon nitride (g-C3N4) for simultaneous oxidation and adsorption of arsenic.

    abstract::Iron-modified graphitic carbon nitride (FG materials) was prepared through a simple and cost-effective method using iron oxide and melamine to achieve simultaneous oxidation and adsorption of arsenic. We hypothesized that graphitic carbon nitride oxidizes As(III) to As(V) under light irradiation, and the converted As(...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2020.109832

    authors: Kim JG,Kim HB,Choi JH,Baek K

    更新日期:2020-09-01 00:00:00

  • Urinary phthalate metabolites are associated with insulin resistance in obese subjects.

    abstract::Phthalates are potentially involved in the development of type 2 diabetes mellitus. In a cohort of 123 obese subjects, 10 phthalate metabolites were analyzed. An oral glucose tolerance test was performed and various estimates of insulin resistance and beta-cell function were calculated. After adjustment for age, physi...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2015.01.010

    authors: Dirinck E,Dirtu AC,Geens T,Covaci A,Van Gaal L,Jorens PG

    更新日期:2015-02-01 00:00:00

  • Virgin microplastics cause toxicity and modulate the impacts of phenanthrene on biomarker responses in African catfish (Clarias gariepinus).

    abstract::Despite the ubiquity of microplastics (MPs) in aquatic environments and their proven ability to carry a wide variety of chemicals, very little is known about the impacts of virgin or contaminant-loaded MPs on organisms. The primary aim of this study was to investigate the impacts of virgin or phenanthrene (Phe)-loaded...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2016.07.024

    authors: Karami A,Romano N,Galloway T,Hamzah H

    更新日期:2016-11-01 00:00:00

  • A comparison of individual exposure, perception, and acceptable levels of PM2.5 with air pollution policy objectives in China.

    abstract::Atmospheric pollution has emerged as a major public health issue in China. Public perception and acceptable risk levels of air pollution can prompt individual behavioral changes and play a major role in the public's response to health risks. Therefore, to explore these responses and evaluate what constitutes publicly ...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2017.05.012

    authors: Huang L,Rao C,van der Kuijp TJ,Bi J,Liu Y

    更新日期:2017-08-01 00:00:00

  • Green spaces and cognitive development at age 7 years in a rome birth cohort: The mediating role of nitrogen dioxide.

    abstract::Introduction There is evidence of improvement on mental health and well-being due to contact with green spaces, through various mechanisms and with potentially differential impacts in different populations. Many of these studies have been conducted among adults, while children have not been sufficiently investigated. ...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2020.110358

    authors: Asta F,Michelozzi P,Cesaroni G,De Sario M,Davoli M,Porta D

    更新日期:2020-10-24 00:00:00

  • Measurement of 16 volatile organic compounds in restaurant air contaminated with environmental tobacco smoke.

    abstract::Tobacco smoke-related air pollutant levels were studied in ten Finnish restaurants. Markers of tobacco smoke were measured together with other compounds typical of tobacco smoke and indoor air. The measurements were carried out at stationary sampling points in smoking and non-smoking areas of the restaurants in 2005-2...

    journal_title:Environmental research

    pub_type: 杂志文章

    doi:10.1016/j.envres.2008.07.020

    authors: Vainiotalo S,Väänänen V,Vaaranrinta R

    更新日期:2008-11-01 00:00:00