Abstract:
:The combined effects of cigarette smoke inhalation and hydrocortisone acetate (HCA) treatment induce prominent abnormalities in lungs of C57BL/6 male mice. These abnormalities include (1) a marked reduction of pulmonary macrophage population which is normally elevated by smoke inhalation, (2) an accumulation of surfactant and flocculent material in alveoli, (3) a decrease in alveolar space surrounded by normal septal tissue, and (4) an increase in hypertrophied alveolar parenchyma. Concomitant with altered lung morphology, lung volume and gas diffusing capacity were significantly compromised in animals subjected to smoke exposure and steroid treatment. It was found that smoke inhalation or HCA administration alone had no ill effects on the animals. The data presented indicate that manifestation of pathologic conditions resembling pulmonary fibrosis and pulmonary alveolar proteinosis is a result of cigarette smoke-drug interaction. The information reported provides a basis for an animal model which might be applicable to assessment of factors related to smoke inhalation and development of pulmonary disorders.
journal_name
Environ Resjournal_title
Environmental researchauthors
Matulionis DH,Kimmel E,Diamond Ldoi
10.1016/0013-9351(85)90026-xsubject
Has Abstractpub_date
1985-04-01 00:00:00pages
298-313issue
2eissn
0013-9351issn
1096-0953pii
0013-9351(85)90026-Xjournal_volume
36pub_type
杂志文章abstract::This study was designed to assess oxidative stress induction in human neuroblastoma SH-SY5Y cells in response to cyfluthrin exposure. Cell viability MTT assay was carried out to assess cyfluthrin cytotoxicity; IC30 and IC50 values for cyfluthrin were calculated to be 4.81 ± 0.92 μM and 19.39 ± 3.44 μM, respectively. C...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2019.108579
更新日期:2019-10-01 00:00:00
abstract::Lead (Pb) is a non-essential metal. Exposure to lead has been associated with adverse health effects in both children and adults. Lead content in paint used in toys or children's products has been identified as both a potential and preventable source of childhood lead exposure. Twenty-four stores located in Bogotá (Co...
journal_title:Environmental research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.envres.2013.11.005
更新日期:2014-01-01 00:00:00
abstract::Polychlorobiphenyls (PCBs), polybromodiphenylethers (PBDEs) and organochlorine pesticides (OCPs), such as dichlorodiphenyltrichloroethane (DDT) and hexachlorobenzene (HCB), are considered as endocrine disruptors in laboratory and wild animals. This study investigated whether these compounds and their hydroxylated meta...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2012.09.004
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVES:We systematically reviewed the published studies on the relationship between dengue fever and meteorological factors and applied a meta-analysis to explore the effects of ambient temperature and precipitation on dengue fever. METHODS:We completed the literature search by the end of September 1st, 2019 using...
journal_title:Environmental research
pub_type: 杂志文章,meta分析
doi:10.1016/j.envres.2020.110043
更新日期:2020-12-01 00:00:00
abstract::At 56 days of age, male and female Long-Evans rats received 1 mumole of 203Hg-labeled methyl mercuric chloride per kilogram sc and total, organic, and inorganic mercury contents and concentrations in tissues were determined for up to 98 days postdosing. Whole body clearance of mercury was faster in females than in mal...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/s0013-9351(86)80184-0
更新日期:1986-10-01 00:00:00
abstract:BACKGROUND:Cadmium exposure was found to cause a decline in lung function among the general population, but these findings were limited to smokers and gender differences were not explored. OBJECTIVES:To examine the relationship between cadmium and chronic obstructive pulmonary disease (COPD) according to gender and sm...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2014.04.008
更新日期:2014-07-01 00:00:00
abstract::There are abundant data and advisories for mercury levels in wild fish, but far fewer for commercial fish that compose a large majority of the fish most people eat. Until recently, relatively little attention has been devoted to examining mercury in canned tuna, despite its great importance in human diets. There is su...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2003.12.001
更新日期:2004-11-01 00:00:00
abstract::Fimbristylis dichotoma, Ammannia baccifera and their co-plantation consortium FA independently degraded Methyl Orange, simulated dye mixture and real textile effluent. Wild plants of F. dichotoma and A. baccifera with equal biomass showed 91% and 89% decolorization of Methyl Orange within 60h at a concentration of 50p...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2017.09.009
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Silver nanoparticles (Ag-NPs) are among the most commonly used nanomaterials and may be exposed to human and ecosystem. Prior in vitro study showed that Ag-NPs compromised neurodevelopment of PC12 cells. This study aims to investigate the effect of prenatal exposure to Ag-NPs on spatial cognition and hippoca...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2015.01.022
更新日期:2015-04-01 00:00:00
abstract::Food safety assessment and communication have a strong importance in reducing human health risks related to food consumption. The research carried out within the ECsafeSEAFOOD project aims to assess seafood safety issues, mainly related to non-regulated priority environmental contaminants, and to evaluate their impact...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2015.06.038
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:Exposure to heavy metals may increase risk of kidney disease, but most studies have examined individual metals or two-way interactions. There is increasing recognition of the importance of studying exposure to metal mixtures and health outcomes. OBJECTIVES:We used Bayesian kernel machine regression (BKMR) t...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110126
更新日期:2020-12-01 00:00:00
abstract::Microplastics (MPs) in the Arctic have raised increasing concern, but knowledge on MP contamination in benthic organisms from Arctic shelf regions, e.g., the Chukchi Sea is still limited. Therefore, the present study investigated the occurrence, characteristics, sources, and environmental implications of MPs in the th...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110326
更新日期:2021-01-01 00:00:00
abstract::Associated with numerous cognitive and behavioral functions and with several diseases, the prefrontal cortex is vulnerable to environmental insult. Among other factors, toxins in air pollution have been associated with damage to the prefrontal cortex in children and older adults. We used data from the UK Biobank to as...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109365
更新日期:2020-06-01 00:00:00
abstract::Gold nanorods (AuNRs) are promising nanoscale materials for several technological and biomedical applications. The physicochemical properties of AuNRs, including size, shape and surface features, are crucial factors affecting their cytotoxicity. In this study, we investigated the effects of different aspect ratios of ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110133
更新日期:2020-12-01 00:00:00
abstract::The high exposure risks of workers to herbicides in low- and middle-income countries is an important public health concern because of the potential resulting negative impacts on workers' health. This study investigated workers' personal protective equipment (PPE) compliance as a risk mitigation measure; particularly w...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2015.05.028
更新日期:2015-10-01 00:00:00
abstract::Source apportionment in biological or environmental samples using the lead isotope method, where there are diverse sources of lead, relies on a significant difference between the isotopic composition in the target media and the sources. Because of the unique isotopic composition of Australian lead, source apportionmen...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2005.03.006
更新日期:2006-01-01 00:00:00
abstract::Ciguatera fish poisoning (CFP) is one of the most devastating food-borne illnesses caused by fish consumption. Ciguatoxins (CTXs) are potent neurotoxins synthesized by the benthic microalgae Gambierdiscus spp. and Fukuyoa spp. that are transmitted to fish by grazing and predation. Despite the high incidence of CFP, af...
journal_title:Environmental research
pub_type: 杂志文章,评审
doi:10.1016/j.envres.2020.109111
更新日期:2020-03-01 00:00:00
abstract::Noise pollution is a major environmental problem due to its impact on human health and implications for other spheres of society. Since road traffic is the main source of noise pollution, the use of measurement methodologies to accurately determine the environmental noise levels to which the façades of buildings in ci...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110055
更新日期:2020-12-01 00:00:00
abstract::Samples from 75 paint products made by 21 domestic and foreign manufacturers were purchased from retail stores in five major cities in Nepal and tested for lead content. Information provided on product labels were noted. Samples were selected to be representative of the large number of brands and colors available in r...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2014.03.036
更新日期:2014-07-01 00:00:00
abstract::Epidemiological studies have not revealed any significant health hazards from exposure to fibrous glass and animal experiments have been inconclusive. Baboons exposed to a fibrous-glass dust cloud with size features similar to those of crocidolite asbestos developed focal peribronchiolar fibrosis with scant ferruginou...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/0013-9351(83)90117-2
更新日期:1983-12-01 00:00:00
abstract::Penetration of 2,4,5,2',4',5'-[14C]hexachlorobiphenyl (HCB) through skin of young (33 days) and adult (82 days) female Fischer 344 rats was determined in vivo and by two in vitro methods. In vivo dermal penetration at 120 hr was 45% in young and 43% in adults. At 72 hr in vivo dermal penetration was 35% in young and 2...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/s0013-9351(89)80053-2
更新日期:1989-10-01 00:00:00
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journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2018.11.024
更新日期:2019-02-01 00:00:00
abstract::Within a cross-sectional study, the neurotoxic effects of occupational exposure to manganese were examined. From a group of 90 (58 male and 32 female) workers, 11 men with long-term and high exposure to manganese dioxide (MnO2) dust were defined as exposed workers. Eleven age-matched workers of similar socioeconomic s...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1006/enrs.2000.4068
更新日期:2001-01-01 00:00:00
abstract::This study evaluated the variation over a year in airborne endotoxin levels in the indoor environment of five university laboratories in Seoul, South Korea, and examined the micro-environmental factors that influenced endotoxin levels. These included temperature, relative humidity, CO2, CO, illumination, and wind velo...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2015.11.025
更新日期:2016-02-01 00:00:00
abstract::Iron-modified graphitic carbon nitride (FG materials) was prepared through a simple and cost-effective method using iron oxide and melamine to achieve simultaneous oxidation and adsorption of arsenic. We hypothesized that graphitic carbon nitride oxidizes As(III) to As(V) under light irradiation, and the converted As(...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.109832
更新日期:2020-09-01 00:00:00
abstract::Phthalates are potentially involved in the development of type 2 diabetes mellitus. In a cohort of 123 obese subjects, 10 phthalate metabolites were analyzed. An oral glucose tolerance test was performed and various estimates of insulin resistance and beta-cell function were calculated. After adjustment for age, physi...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2015.01.010
更新日期:2015-02-01 00:00:00
abstract::Despite the ubiquity of microplastics (MPs) in aquatic environments and their proven ability to carry a wide variety of chemicals, very little is known about the impacts of virgin or contaminant-loaded MPs on organisms. The primary aim of this study was to investigate the impacts of virgin or phenanthrene (Phe)-loaded...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2016.07.024
更新日期:2016-11-01 00:00:00
abstract::Atmospheric pollution has emerged as a major public health issue in China. Public perception and acceptable risk levels of air pollution can prompt individual behavioral changes and play a major role in the public's response to health risks. Therefore, to explore these responses and evaluate what constitutes publicly ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2017.05.012
更新日期:2017-08-01 00:00:00
abstract::Introduction There is evidence of improvement on mental health and well-being due to contact with green spaces, through various mechanisms and with potentially differential impacts in different populations. Many of these studies have been conducted among adults, while children have not been sufficiently investigated. ...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2020.110358
更新日期:2020-10-24 00:00:00
abstract::Tobacco smoke-related air pollutant levels were studied in ten Finnish restaurants. Markers of tobacco smoke were measured together with other compounds typical of tobacco smoke and indoor air. The measurements were carried out at stationary sampling points in smoking and non-smoking areas of the restaurants in 2005-2...
journal_title:Environmental research
pub_type: 杂志文章
doi:10.1016/j.envres.2008.07.020
更新日期:2008-11-01 00:00:00