Tuberculosis in children 10 years of age and younger: three decades of experience during the chemotherapeutic era.

Abstract:

:The 863 patients, aged 10 years and younger, treated at the Children's Chest Clinic of Bellevue Hospital during three decades (1953 through 1981) clearly indicated the success of antituberculosis therapy. There were no deaths from tuberculosis. Early treatment is associated with a reduction in the serious forms of disease, eg, meningitis, miliary disease, and bone infections, and with preventing death. Medication was well tolerated: only 1.1% of the patients had adverse reactions, all of which were reversible. Consistent compliance with medication of only 62% of patients is a challenge to the medical profession. Only 22.5% of mycobacterial cultures were positive. Long-term follow-up of patients was rewarding: seven pregnancies with healthy mothers and babies, and no reactivation of tuberculosis by later infections, even those such as measles or pneumonia. The severity of disease was related largely to patient's age (3 years and younger) and intimacy of contact, the highest rate being when the mother was the contact. The long-term experiences emphasizes the value of early identification, therapeutic compliance, and comprehensive contact, tracing in the future elimination of tuberculosis. Prophylactic therapy and close observation should be considered for contacts, especially those exposed to human immunodeficiency virus infections and addicted to drugs.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Nemir RL,O'Hare D

subject

Has Abstract

pub_date

1991-08-01 00:00:00

pages

236-41

issue

2

eissn

0031-4005

issn

1098-4275

journal_volume

88

pub_type

杂志文章
  • US Emergency Department Trends in Imaging for Pediatric Nontraumatic Abdominal Pain.

    abstract:OBJECTIVES:To describe national emergency department (ED) trends in computed tomography (CT) and ultrasound imaging for the evaluation of pediatric nontraumatic abdominal pain from 2007 through 2014. METHODS:We used data from the National Hospital Ambulatory Medical Care Survey to measure trends in CT and ultrasound u...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2017-0615

    authors: Niles LM,Goyal MK,Badolato GM,Chamberlain JM,Cohen JS

    更新日期:2017-10-01 00:00:00

  • Phototherapy to prevent severe neonatal hyperbilirubinemia in the newborn infant 35 or more weeks of gestation.

    abstract:OBJECTIVE:To standardize the use of phototherapy consistent with the American Academy of Pediatrics clinical practice guideline for the management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. METHODS:Relevant literature was reviewed. Phototherapy devices currently marketed in the United S...

    journal_title:Pediatrics

    pub_type: 杂志文章,实务指引

    doi:10.1542/peds.2011-1494

    authors: Bhutani VK,Committee on Fetus and Newborn.,American Academy of Pediatrics.

    更新日期:2011-10-01 00:00:00

  • Trends in Capability of Hospitals to Provide Definitive Acute Care for Children: 2008 to 2016.

    abstract:BACKGROUND:Provision of high-quality care to acutely ill and injured children is a challenge to US hospitals because many have low pediatric volume. Delineating national trends in definitive pediatric acute care would inform improvements in care. METHODS:We analyzed emergency department (ED) visits by children between...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-2203

    authors: Michelson KA,Hudgins JD,Lyons TW,Monuteaux MC,Bachur RG,Finkelstein JA

    更新日期:2020-01-01 00:00:00

  • Defining asthma in the preschool-aged child.

    abstract::A physician faces many challenges in making a definitive diagnosis of asthma in young children. Although there are clinical and historical features consistent with asthma, identical features are present in many other diseases. Furthermore, there is no specific test for asthma. Other diseases must always be ruled out b...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Strunk RC

    更新日期:2002-02-01 00:00:00

  • School-age outcomes in children who were extremely low birth weight from four international population-based cohorts.

    abstract:OBJECTIVE:The aim of this study was to determine whether learning and school problems in extremely low birth weight (ELBW) and reference children differ between cohorts in different countries. METHODS:Participants were 4 international population-based cohorts of ELBW survivors who were 500 to 1000 g birth weight from ...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.112.4.943

    authors: Saigal S,den Ouden L,Wolke D,Hoult L,Paneth N,Streiner DL,Whitaker A,Pinto-Martin J

    更新日期:2003-10-01 00:00:00

  • Low-income parents' views on the redesign of well-child care.

    abstract:OBJECTIVE:To examine the perspectives of low-income parents on redesigning well-child care (WCC) for children aged 0 to 3 years, focusing on possible changes in 3 major domains: providers, locations, and formats. METHODS:Eight focus groups (4 English and 4 Spanish) were conducted with 56 parents of children aged 6 mon...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-2608

    authors: Coker TR,Chung PJ,Cowgill BO,Chen L,Rodriguez MA

    更新日期:2009-07-01 00:00:00

  • Growth pattern of breastfed and nonbreastfed infants with atopic dermatitis in the first year of life.

    abstract:OBJECTIVE:The growth of infants with atopic dermatitis (AD) has been poorly investigated based on the early type of feeding. The aim of this study was to assess the growth pattern of AD infants during the first 12 months of life in comparison to healthy infants, according to the early type of feeding (breastfed or nonb...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.106.5.e73

    authors: Agostoni C,Grandi F,Scaglioni S,Giannì ML,Torcoletti M,Radaelli G,Fiocchi A,Riva E

    更新日期:2000-11-01 00:00:00

  • Renal and absorptive hypercalciuria: a metabolic disturbance with varying and interchanging modes of expression.

    abstract:BACKGROUND:In previous studies, the oral calcium loading and deprivation test has been used to distinguish between children with renal (fasting) hypercalciuria (RH) and absorptive hypercalciuria (AH). OBJECTIVE:We evaluated the long-term clinical course of 30 children with idiopathic hypercalciuria and investigated th...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Aladjem M,Barr J,Lahat E,Bistritzer T

    更新日期:1996-02-01 00:00:00

  • Parenting Interventions in Pediatric Primary Care: A Systematic Review.

    abstract:CONTEXT:More than 4 decades of research indicate that parenting interventions are effective at preventing and treating mental, emotional, and behavioral disorders in children and adolescents. Pediatric primary care is a viable setting for delivery of these interventions. OBJECTIVE:Previous meta-analyses have shown tha...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-3548

    authors: Smith JD,Cruden GH,Rojas LM,Van Ryzin M,Fu E,Davis MM,Landsverk J,Brown CH

    更新日期:2020-07-01 00:00:00

  • Global Health: Preparation for Working in Resource-Limited Settings.

    abstract::Trainees and clinicians from high-income countries are increasingly engaging in global health (GH) efforts, particularly in resource-limited settings. Concomitantly, there is a growing demand for these individuals to be better prepared for the common challenges and controversies inherent in GH work. This is a state-of...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2016-3783

    authors: St Clair NE,Pitt MB,Bakeera-Kitaka S,McCall N,Lukolyo H,Arnold LD,Audcent T,Batra M,Chan K,Jacquet GA,Schutze GE,Butteris S,Global Health Task Force of the American Board of Pediatrics.

    更新日期:2017-11-01 00:00:00

  • Diagnosing Infection in a Neonate Using Whole-Body Screening Magnetic Resonance Imaging.

    abstract::The location of invasive infections is difficult to detect in infants, in part due to their inability to localize signs and symptoms. However, identifying the location often significantly alters clinical management by extending the duration of antibiotic therapy or revealing a source requiring surgical intervention. C...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2016-0732

    authors: Fu TT,Kingma PS

    更新日期:2017-12-01 00:00:00

  • Children killed in falls from motor vehicles.

    abstract::In 1978 in the United States, 38 children aged 5 years or younger were killed when they fell from the passenger compartments of moving motor vehicles not involved in crashes. Twenty-eight children (74%) were boys. Eighteen (47%) were 2 years old; 35 (92%) were aged 1 to 3 years. Thirty-six children fell out through do...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Williams AF

    更新日期:1981-10-01 00:00:00

  • Etiology of childhood bacteremia and timely antibiotics administration in the emergency department.

    abstract:BACKGROUND:Bacteremia is now an uncommon presentation to the children's emergency department (ED) but is associated with significant morbidity and mortality. Its evolving etiology may affect the ability of clinicians to initiate timely, appropriate antimicrobial therapy. METHODS:A retrospective time series analysis of...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2014-2061

    authors: Irwin AD,Drew RJ,Marshall P,Nguyen K,Hoyle E,Macfarlane KA,Wong HF,Mekonnen E,Hicks M,Steele T,Gerrard C,Hardiman F,McNamara PS,Diggle PJ,Carrol ED

    更新日期:2015-04-01 00:00:00

  • The adverse effect of negative comments about weight and shape from family and siblings on women at high risk for eating disorders.

    abstract:OBJECTIVE:Our purpose with this work was to examine the relationship between negative comments about weight, shape, and eating and social adjustment, social support, self-esteem, and perceived childhood abuse and neglect. METHODS:A retrospective study was conducted with 455 college women with high weight and shape con...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2005-1806

    authors: Taylor CB,Bryson S,Celio Doyle AA,Luce KH,Cunning D,Abascal LB,Rockwell R,Field AE,Striegel-Moore R,Winzelberg AJ,Wilfley DE

    更新日期:2006-08-01 00:00:00

  • The infant development, environment, and lifestyle study: effects of prenatal methamphetamine exposure, polydrug exposure, and poverty on intrauterine growth.

    abstract:OBJECTIVE:Methamphetamine use among pregnant women is an increasing problem in the United States. Effects of methamphetamine use during pregnancy on fetal growth have not been reported in large, prospective studies. We examined the neonatal growth effects of prenatal methamphetamine exposure in the multicenter, longitu...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.2005-2564

    authors: Smith LM,LaGasse LL,Derauf C,Grant P,Shah R,Arria A,Huestis M,Haning W,Strauss A,Della Grotta S,Liu J,Lester BM

    更新日期:2006-09-01 00:00:00

  • Variation in Family Experience of Pediatric Inpatient Care As Measured by Child HCAHPS.

    abstract:BACKGROUND:Making national comparisons of family experience of inpatient pediatric care has been limited by the lack of a publicly available survey. The Agency for Healthcare Research and Quality and Centers for Medicare & Medicaid Services commissioned development of the Child Hospital Consumer Assessment of Healthcar...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2016-3372

    authors: Toomey SL,Elliott MN,Zaslavsky AM,Klein DJ,Ndon S,Hardy S,Wu M,Schuster MA

    更新日期:2017-04-01 00:00:00

  • Children in alcohol-related motor vehicle crashes.

    abstract::Review of North Carolina traffic crash data revealed that alcohol use, although associated with 7.9% of motor vehicle crashes involving children, accounted for 15.4% of the motor vehicle-related deaths and 10.4% of the injuries. The largest proportion of these deaths were child passengers in a vehicle in which the dri...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Margolis LH,Kotch J,Lacey JH

    更新日期:1986-06-01 00:00:00

  • Accuracy of infant admission lengths.

    abstract:OBJECTIVE:A variety of methods are used to assess the length of infants at hospital admission. A tape-measure technique is commonly used; however, this measure is potentially inaccurate. We aimed to assess accuracy of tape measurement of infant lengths by comparison with the more accurate length-board technique. METHO...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.109.6.1108

    authors: Corkins MR,Lewis P,Cruse W,Gupta S,Fitzgerald J

    更新日期:2002-06-01 00:00:00

  • Serum luteinizing hormone rises within minutes after depot leuprolide injection: implications for monitoring therapy.

    abstract:OBJECTIVE:To find the time of the serum gonadotropin peak after depot leuprolide injection in children and to show that depot leuprolide therapy can be monitored by measuring serum luteinizing hormone (LH) immediately after injections. STUDY DESIGN:We measured concentrations of leuprolide, LH, and follicle-stimulating...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.109.2.e30

    authors: Bhatia S,Neely EK,Wilson DM

    更新日期:2002-02-01 00:00:00

  • Survival of transfused normal granulocytes in a patient with chronic granulomatous disease.

    abstract::A 5-year-old boy with chronic granulomatous disease (CGD) received four granulocyte transfusions from unrelated HLA-matched donors as part of therapy for a hepatic abscess. Survival studies of transfused granulocytes using the endotoxin-stimulated nitroblue tetrazolium (NBT) test on two occasions demonstrated 19.6% an...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Chusid MJ,Tomasulo PA

    更新日期:1978-04-01 00:00:00

  • Prevalence of parent-reported diagnosis of autism spectrum disorder among children in the US, 2007.

    abstract:OBJECTIVES:The reported increasing prevalence of autism spectrum disorder (ASD) and attendant health and family impact make monitoring of ASD prevalence a public health priority. METHODS:The prevalence of parent-reported diagnosis of ASD among US children aged 3 to 17 years was estimated from the 2007 National Survey ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2009-1522

    authors: Kogan MD,Blumberg SJ,Schieve LA,Boyle CA,Perrin JM,Ghandour RM,Singh GK,Strickland BB,Trevathan E,van Dyck PC

    更新日期:2009-11-01 00:00:00

  • The Rights of Children for Optimal Development and Nurturing Care.

    abstract::Millions of children are subjected to abuse, neglect, and displacement, and millions more are at risk for not achieving their developmental potential. Although there is a global movement to change this, driven by children's rights, progress is slow and impeded by political considerations. The United Nations Convention...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-0487

    authors: Uchitel J,Alden E,Bhutta ZA,Goldhagen J,Narayan AP,Raman S,Spencer N,Wertlieb D,Wettach J,Woolfenden S,Mikati MA

    更新日期:2019-12-01 00:00:00

  • Stunting of growth as a major feature of anorexia nervosa in male adolescents.

    abstract:OBJECTIVE:To assess growth retardation in male adolescent patients who have a diagnosis of anorexia nervosa (AN) and the effect of weight restoration on catch-up growth. METHODS:Medical charts of all male adolescent AN patients (n = 12) who were admitted to the Pediatric Psychosomatic Department at the Sheba Medical C...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.111.2.270

    authors: Modan-Moses D,Yaroslavsky A,Novikov I,Segev S,Toledano A,Miterany E,Stein D

    更新日期:2003-02-01 00:00:00

  • Do questions about lead exposure predict elevated lead levels?

    abstract:OBJECTIVE:To assess the usefulness of the lead poisoning questionnaire developed by the Centers for Disease Control and Prevention as a screening tool for elevated lead levels. METHODS:This descriptive study used a five-question questionnaire at our hospital-based general pediatric clinic and in two local private prac...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Tejeda DM,Wyatt DD,Rostek BR,Solomon WB

    更新日期:1994-02-01 00:00:00

  • Nocturnal arterial oxygen saturation and academic performance in a community sample of children.

    abstract:OBJECTIVE:Hypoxemia, often assessed via pulse oximetry, is associated with neurocognitive deficits in children. The best way to qualify hypoxemia, or which level of hypoxemia already affects cognition, is unknown. METHODS:We assessed the association of pulse oximetry-derived variables that qualify hypoxemia with impai...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-1256

    authors: Urschitz MS,Wolff J,Sokollik C,Eggebrecht E,Urschitz-Duprat PM,Schlaud M,Poets CF

    更新日期:2005-02-01 00:00:00

  • Correlates of objectively measured sedentary behavior in US preschool children.

    abstract:OBJECTIVE:To identify correlates of objectively measured sedentary behavior in a diverse sample of preschool children. METHODS:A total of 331 children (51% male, 51% black) from a wide range of ethnic and socioeconomic backgrounds in greater Columbia, South Carolina, were recruited for this study. Sedentary behavior (...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2011-0748

    authors: Byun W,Dowda M,Pate RR

    更新日期:2011-11-01 00:00:00

  • Sleep deprivation for pediatric sedated procedures: not worth the effort.

    abstract:OBJECTIVE:Sleep deprivation is commonly used to enhance the effectiveness of pediatric sedation and to decrease sedation failures. We reviewed our sedation database to evaluate the efficacy of sleep deprivation. METHODS:The entire pediatric sedation unit database (n = 5640) was reviewed retrospectively. Patients witho...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.113.5.1204

    authors: Shields CH,Johnson S,Knoll J,Chess C,Goldberg D,Creamer K

    更新日期:2004-05-01 00:00:00

  • Lupus nephritis: prognostic factors in children.

    abstract::As newer treatment modalities become available for patients with severe lupus nephritis, it becomes increasingly important to identify patients at risk for renal failure. In this study, the records of 90 children presenting with systemic lupus erythematosus over a 13-year period were reviewed. Nineteen were lost to fo...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: McCurdy DK,Lehman TJ,Bernstein B,Hanson V,King KK,Nadorra R,Landing BH

    更新日期:1992-02-01 00:00:00

  • Randomized, controlled trial on tracheal colonization of ventilated infants: can gravity prevent ventilator-associated pneumonia?

    abstract:OBJECTIVE:The goal was to test the hypothesis that intubated infants positioned on their sides would be less likely to contract bacterial colonization in their tracheae, compared with those positioned supine. METHODS:We conducted a prospective, randomized, controlled trial with 60 intubated infants; 30 infants were po...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2007-1826

    authors: Aly H,Badawy M,El-Kholy A,Nabil R,Mohamed A

    更新日期:2008-10-01 00:00:00

  • Determinants of Social Outcomes in Adults With Childhood-onset Epilepsy.

    abstract:BACKGROUND:Adults with childhood-onset epilepsy experience poorer adult social outcomes than their peers. The relative roles of seizures over time versus learning and psychiatric problems are unclear. METHODS:We examined independent influences of psychiatric and learning disorders and of seizure course in 241 young ad...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2015-3944

    authors: Berg AT,Baca CB,Rychlik K,Vickrey BG,Caplan R,Testa FM,Levy SR

    更新日期:2016-04-01 00:00:00