Calcified plaque: measurement of area at thin-section flat-panel CT and 64-section multidetector CT and comparison with histopathologic findings.

Abstract:

:The purpose of this study was to assess the blooming artifacts in ex vivo coronary arteries at multidetector computed tomography (CT) and flat-panel-volume CT by comparing measured areas of calcified plaque with respect to the reference standard of histopathologic findings. Three ex vivo hearts were scanned with multidetector CT and flat-panel-volume CT after institutional review board approval. The area of calcified plaque was measured at histopathologic examination, multidetector CT, and flat-panel-volume CT. The plaque area was overestimated at multidetector CT by 400% (4.61/1.15) on average, and the predicted difference between the measurements was significant (3.46 mm(2), P = .018). The average overestimation of plaque area at flat-panel-volume CT was twofold (214% [2.18/1.02]), and the predicted difference was smaller (1.16 mm(2), P = .08). The extent of the blooming artifact in visualizing calcified coronary plaque is reduced by using flat-panel-volume CT.

journal_name

Radiology

journal_title

Radiology

authors

Sarwar A,Rieber J,Mooyaart EA,Seneviratne SK,Houser SL,Bamberg F,Raffel OC,Gupta R,Kalra MK,Pien H,Lee H,Brady TJ,Hoffmann U

doi

10.1148/radiol.2483072003

subject

Has Abstract

pub_date

2008-10-01 00:00:00

pages

301-6

issue

1

eissn

0033-8419

issn

1527-1315

pii

2483072003

journal_volume

249

pub_type

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