当前位置： SCI文献检索 > AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY期刊下所有文献 > The effects of aminophylline and nifedipine on contractility of isolated pregnant human myometrium.

The effects of aminophylline and nifedipine on contractility of isolated pregnant human myometrium.

Abstract：

:To characterize the effects of aminophylline and nifedipine on pregnant human myometrium, in vitro contractility studies were performed on myometrial strips obtained at cesarean section. The strips were stimulated with oxytocin (800 mU/L) to simulate labor and then were exposed to increasing concentrations of aminophylline (40, 100, and 400 mumol/L) or nifedipine (5, 10, and 20 micrograms/L). Both drugs produced a dose-related decrease in contraction strength, as measured by the time-integrated force of contraction. Aminophylline lengthened the period of contraction in a manner that was not dose dependent. Low-dose nifedipine (5 micrograms/L) increased the period of contraction, but higher doses had no effect on frequency. Both drugs produced a net reduction in the effectiveness of labor, as measured by the average force (time-integrated force divided by period). These results indicate that both aminophylline and nifedipine may be clinically useful tocolytic agents.

journal_name

Am J Obstet Gynecol

journal_title

American journal of obstetrics and gynecology

authors

Bird LM,Anderson NC Jr,Chandler ML,Young RC

doi

10.1016/s0002-9378(87)80373-3

subject

Has Abstract

pub_date

1987-07-01 00:00:00

pages

171-7

issue

1

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(87)80373-3

journal_volume

157

pub_type

杂志文章

相关文献

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY文献大全
  • Catecholamine metabolites in amniotic fluid as indicators of intrauterine stress.

    abstract：:The catecholamine metabolites HMPG and VMA have been determined in samples of amniotic fluid in 38 uncomplicated pregnancies, seven cases of IUGR, and six cases of diabetes. A successive increase of HMPG and VMA was found toward the end of the pregnancy. HMPG and particularly the HMPG/VMA ratio were significantly high...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(80)90639-0

    authors： Lagercrantz H,Sjöquist B,Bremme K,Lunell NO,Somell C

    更新日期：1980-04-15 00:00:00

  • Transvaginal ultrasonographic characterization of ovarian masses by means of color flow-directed Doppler measurements and a morphologic scoring system.

    abstract：OBJECTIVE:The aim of the study was to test the hypothesis that a combination of a previously devised morphologic scoring system and color flow-directed Doppler measurements would afford better discrimination between benign and malignant ovarian masses. STUDY DESIGN:The scoring system and color flow-directed Doppler me...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(12)90843-1

    authors： Timor-Tritsch LE,Lerner JP,Monteagudo A,Santos R

    更新日期：1993-03-01 00:00:00

  • Endometrial adenocarcinoma estrogen receptor content: association of clinicopathologic features with immunohistochemical analysis compared with standard biochemical methods.

    abstract：:Endometrial adenocarcinomas from 96 patients were studied for their biochemical estrogen receptor content as well as immunohistochemical localization of estrogen receptor. A well-characterized specific monoclonal antihuman estrogen receptor antibody (H222 sp gamma) as amplified by peroxidase/antiperoxidase techniques ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(87)80090-x

    authors： Mutch DG,Soper JT,Budwit-Novotny DA,Cox EB,Creasman WT,McCarty KS Sr,McCarty KS Jr

    更新日期：1987-10-01 00:00:00

  • The effect of a uterine manipulator on the recurrence and mortality of endometrial cancer: a multi-centric study by the Italian Society of Gynecological Endoscopy.

    abstract：BACKGROUND:Although widely adopted, the use of a uterine manipulator during laparoscopic treatment of endometrial cancer represents a debated issue, and some authors hypothesize that it potentially may cause an increased risk of relapse, particularly at specific sites. OBJECTIVE:Our aim was to evaluate the risk and si...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ajog.2017.01.027

    authors： Uccella S,Bonzini M,Malzoni M,Fanfani F,Palomba S,Aletti G,Corrado G,Ceccaroni M,Seracchioli R,Shakir F,Ferrero A,Berretta R,Tinelli R,Vizza E,Roviglione G,Casarella L,Volpi E,Cicinelli E,Scambia G,Ghezzi F

    更新日期：2017-06-01 00:00:00

  • Decrease of vascular angiotensin sensitivity by L-dopa during human pregnancy.

    abstract：:In 27 pregnant subjects (21 treated women and six control subjects), the effect of L-dopa (500 to 1,000 mg orally) on vascular sensitivity to angiotensin II amide (Hypertensin, Ciba) was examined in 16 of these women, 1,000 mg of L-dopa resulted in a significant decrease in vascular responsiveness to angiotensin, i.e....

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(81)90202-7

    authors： Kaulhausen H,Oney T,Feldmann R,Leyendecker G

    更新日期：1981-07-15 00:00:00

  • Pregnancy-induced hypertension and acute fatty liver of pregnancy: atypical presentations.

    abstract：:Severe pregnancy-induced hypertension and markedly elevated levels of serum alkaline phosphatase developed in a 29-year-old-woman in whom one pregnancy resulted in intrauterine death. Acute fatty liver of pregnancy developed with good fetal outcome in the next pregnancy. This case suggests that pregnancy-induced hyper...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(90)90677-y

    authors： Brown MA,Passaris G,Carlton MA

    更新日期：1990-10-01 00:00:00

  • Small bowel obstruction secondary to a prior Moschcowitz procedure.

    abstract：:The Moschcowitz procedure has been advocated for the correction of large enteroceles. Documented complications of this technique are rare. Following is a review of this procedure with the presentation of a unique delayed complication. ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(85)80086-7

    authors： Dicke JM

    更新日期：1985-08-01 00:00:00

  • Vitamin D deficiency in gestational diabetes mellitus and the role of the placenta.

    abstract：OBJECTIVE:The aim of this study was to evaluate the relationships between maternal vitamin D levels and gestational diabetes mellitus (GDM) and differences in the placental production of vitamin D receptor (VDR), CYP24A, and CYP27B1. STUDY DESIGN:Forty normal pregnant women and 20 women with GDM were included in this ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2013.08.015

    authors： Cho GJ,Hong SC,Oh MJ,Kim HJ

    更新日期：2013-12-01 00:00:00

  • Endometrial resection versus vaginal hysterectomy for menorrhagia: long-term clinical and quality-of-life outcomes.

    abstract：OBJECTIVE:Our purpose was to compare patients' satisfaction with the effect of treatment, health-related quality of life, psychologic status, and sexual functioning 2 years after endometrial resection or vaginal hysterectomy for menorrhagia. STUDY DESIGN:Menorrhagic women < or = 50 years old with a mobile uterus small...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0002-9378(97)70445-9

    authors： Crosignani PG,Vercellini P,Apolone G,De Giorgi O,Cortesi I,Meschia M

    更新日期：1997-07-01 00:00:00

  • Biomechanical characterization of vaginal versus abdominal surgical wound healing in the rabbit.

    abstract：OBJECTIVE:The objective of the study was to compare biomechanical properties of vaginal versus abdominal surgical wound healing in the rabbit. STUDY DESIGN:Bilateral 6-mm full-thickness circular segments were excised from the vagina and abdominal skin in 38 New Zealand White female rabbits. Animals were killed 0, 4, 7...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2006.01.063

    authors： Abramov Y,Webb AR,Miller JJ,Alshahrour A,Botros SM,Goldberg RP,Ameer GA,Sand PK

    更新日期：2006-05-01 00:00:00

  • Postmenopausal steroid replacement with micronized dehydroepiandrosterone: preliminary oral bioavailability and dose proportionality studies.

    abstract：OBJECTIVES:Because dehydroepiandrosterone may protect against neoplasia, osteoporosis, and cardiac disease, we investigated the bioavailability of oral micronized dehydroepiandrosterone, anticipating its adjunctive use in postmenopausal steroid replacement. STUDY DESIGN:Eight postmenopausal women randomly received eit...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：

    authors： Buster JE,Casson PR,Straughn AB,Dale D,Umstot ES,Chiamori N,Abraham GE

    更新日期：1992-04-01 00:00:00

  • Fetal heart rate changes following maternal administration of a nasal decongestant.

    abstract：:Repeated use of a long-acting sympathomimetic amine in the form of a nasal spray was associated with a nonreactive nonstress test and late decelerations in a patient at 41 weeks of gestation. Six hours after the last dose, these changes gradually disappeared. ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(85)90351-5

    authors： Baxi LV,Gindoff PR,Pregenzer GJ,Parras MK

    更新日期：1985-12-01 00:00:00

  • The rhesus macaque as an animal model for pelvic organ prolapse.

    abstract：OBJECTIVE:The purpose of this study was to characterize the pelvic floor of the rhesus macaque as an experimental model for human pelvic organ prolapse and to initiate an evaluation of the effects of estradiol and progesterone on the rhesus paravaginal attachment. STUDY DESIGN:Histologic specimens were prepared from t...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2002.121723

    authors： Otto LN,Slayden OD,Clark AL,Brenner RM

    更新日期：2002-03-01 00:00:00

  • Single-dose cephalosporin for prevention of major pelvic infection after vaginal hysterectomy: cefazolin versus cefoxitin versus cefotaxime.

    abstract：:Antimicrobial overutilization accelerates the development of bacterial resistance. A prospective, randomized, blinded clinical trial of vaginal hysterectomy prophylaxis was designed to compare the efficacy, safety, and costs of cefazolin with those of cefoxitin and cefotaxime. Sixteen women (7.5%) developed febrile mo...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0002-9378(87)90144-x

    authors： Hemsell DL,Bawdon RE,Hemsell PG,Nobles BJ,Johnson ER,Heard MC

    更新日期：1987-05-01 00:00:00

  • The accuracy of the summated amniotic fluid index in evaluating amniotic fluid volume in twin pregnancies.

    abstract：OBJECTIVE:Our purpose was to determine the accuracy of the summated amniotic fluid index designed to estimate the total amniotic fluid volume in twin pregnancies. STUDY DESIGN:The summated amniotic fluid index was measured in 62 normal diamniotic twin pregnancies by adding the deepest vertical pockets in the four quad...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(97)70011-5

    authors： Magann EF,Chauhan SP,Whitworth NS,Klausen JH,Nevils BG,Morrison JC

    更新日期：1997-11-01 00:00:00

  • Patient-recorded domiciliary fetal monitoring.

    abstract：:Domiciliary fetal monitoring via a telephone link has been in clinical use at the Royal Free Hospital for 2 years, during which time 858 traces of 134 patients who were moderately at risk have been transmitted to the hospital. All recognized abnormal heart rate patterns were detected during the study period. In seven ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(90)90411-y

    authors： Lindsay PC,Beveridge R,Tayob Y,Irvine LM,Vellacott ID,Giles JA,Hussain SY,O'Brien PM

    更新日期：1990-02-01 00:00:00

  • Ovarian vein thrombosis after debulking surgery for ovarian cancer: epidemiology and clinical significance.

    abstract：OBJECTIVE:Ovarian vein thrombosis is associated with pregnancy and pelvic surgery. Postpartum ovarian vein thrombosis is associated with infection and a high morbidity rate and is treated with anticoagulant and intravenous antibiotic therapy. The natural history of such thrombotic events after debulking surgery for ova...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2015.02.028

    authors： Mantha S,Sarasohn D,Ma W,Devlin SM,Chi DS,Roche KL,Suidan RS,Woo K,Soff GA

    更新日期：2015-08-01 00:00:00

  • Prenatal diagnosis of 46,XX male fetuses.

    abstract：:Ultrasonography can accurately determine phenotypic sex differences from those of the genetic sex. Two cases were identified; they were the result of a translocation of the SRY gene from the Y chromosome to the X chromosome during meiosis. An ultrasonographic difference may represent an otherwise unsuspected genetic a...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(99)70673-3

    authors： Ginsberg NA,Cadkin A,Strom C,Bauer-Marsh E,Verlinsky Y

    更新日期：1999-04-01 00:00:00

  • Reduced umbilical artery prostacyclin formation in complicated pregnancies.

    abstract：:Prostacyclin synthesis is severely depressed in the umbilical arteries of neonates of mothers with gestational diabetes mellitus, juvenile-onset diabetes mellitus, or preeclamptic symptoms, and of mothers who smoke during pregnancy and diabetic mothers who smoke. The reduced production of prostacyclin might be respons...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(82)90354-4

    authors： Dadak C,Kefalides A,Sinzinger H,Weber G

    更新日期：1982-12-01 00:00:00

  • Prevention of diabetes-associated embryopathy by overexpression of the free radical scavenger copper zinc superoxide dismutase in transgenic mouse embryos.

    abstract：OBJECTIVES:It has recently been suggested that oxygen free radicals are involved in the high incidence of fetal dysmorphogenesis that is associated with diabetic pregnancies. The purpose of the current investigation was to study the effect of copper zinc superoxide dismutase, a free radical scavenging enzyme, on the pr...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(95)91323-8

    authors： Hagay ZJ,Weiss Y,Zusman I,Peled-Kamar M,Reece EA,Eriksson UJ,Groner Y

    更新日期：1995-10-01 00:00:00

  • Maternal herpes simplex virus antibody avidity and risk of neonatal herpes.

    abstract：OBJECTIVE:The objective of the study was to assess whether herpes simplex virus antibody avidity is associated with risk of transmission of herpes simplex virus to the neonate. STUDY DESIGN:We developed a novel herpes simplex virus type 1 avidity test based on the commercially available Focus HerpeSelect-1 enzyme-link...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2006.02.013

    authors： Brown EL,Morrow R,Krantz EM,Arvin AM,Prober CG,Yasukawa LL,Corey L,Wald A

    更新日期：2006-07-01 00:00:00

  • Midtrimester fetal heart rate variability and maternal hemodynamics in association with smoking.

    abstract：:Maternal heart rate (MHR), blood pressure (BP), the differential index (DI) describing the short-term component of fetal heart rate (FHR) variability, and the interval index (II) describing the long-term component were measured in eight subjects in the midtrimester before, during, and after the mothers smoked a standa...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(83)91013-x

    authors： Forss M,Lehtovirta P,Rauramo I,Kariniemi V

    更新日期：1983-07-15 00:00:00

  • Congenital absence of the umbilical cord resulting from maldevelopment of embryonic body folding.

    abstract：:We report a case of extreme maldevelopment of embryonic body folding that resulted in incomplete fusion of the amnion to the chorion and failure to form an umbilical cord. Massive intra-abdominal and intrathoracic herniation led to rapid neonatal death. The accurate ultrasonic characterization of the defect enabled pr...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(86)90345-5

    authors： Lockwood CJ,Scioscia AL,Hobbins JC

    更新日期：1986-11-01 00:00:00

  • Term birth after midtrimester hysterotomy and selective delivery of an acardiac twin.

    abstract：OBJECTIVE:Our aim was to determine whether hysterotomy and selective removal of an acardiac twin could improve the outcome of the "pump" twin. STUDY DESIGN:A literature and case review of the outcome of the acardiac twin malformation was performed. When an acardiac malformation was diagnosed at 19 weeks' gestation the...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(11)91620-2

    authors： Ginsberg NA,Applebaum M,Rabin SA,Caffarelli MA,Kuuspalu M,Daskal JL,Verlinsky Y,Strom CM,Barton JJ

    更新日期：1992-07-01 00:00:00

  • A comparative study of laparoscopic extraperitoneal lymphadenectomy [correction of laparoscopy] with the use of ultrasonically activated shears.

    abstract：OBJECTIVE:We evaluated the use of the harmonic scalpel in reducing the occurrence of symptomatic lymphoceles and its related complications in paraaortic laparoscopic lymphadenectomies (PALLs). STUDY DESIGN:All PALL that were performed at the Institut Claudius Regaud between January 2003 and June 2007 were included. Si...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2009.05.026

    authors： Rafii A,Camicas A,Ferron G,Mery E,Gladieff L,Delannes M,Querleu D

    更新日期：2009-10-01 00:00:00

  • Genetic polymorphisms in the aryl hydrocarbon receptor signaling pathway as potential risk factors of menopausal hot flashes.

    abstract：OBJECTIVE:We sought to determine if genetic polymorphisms in the aryl hydrocarbon receptor signaling pathway are associated with menopausal hot flashes via hormone levels. STUDY DESIGN:Women (n = 639) aged 45-54 years completed a study survey and provided blood for genetic and hormone analyses. The associations were a...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2012.05.019

    authors： Ziv-Gal A,Gallicchio L,Miller SR,Zacur HA,Flaws JA

    更新日期：2012-09-01 00:00:00

  • The effect of tetracycline on levels of oral contraceptives.

    abstract：:Despite the widespread use of tetracycline for treatment of dermatologic disorders and sexually transmitted diseases, the pharmacodynamics of oral contraceptive use in the presence of tetracycline has not been studied. Seven normal women ingested an oral contraceptive containing ethinyl estradiol 35 micrograms and nor...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(91)90617-z

    authors： Murphy AA,Zacur HA,Charache P,Burkman RT

    更新日期：1991-01-01 00:00:00

  • Morphologic study of changes of collagenous tissue in the amnion and cervix during prostaglandin-induced abortion and delivery.

    abstract：:Marked dissociation of the cervical collagenous tissue during prostaglandin-induced abortion is well recognized, but the response of collagenous tissue of the amnion to prostaglandin treatment is not known. A morphologic study of amniotic collagenous tissue was performed after prostaglandin-induced abortion and prosta...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(11)90666-8

    authors： Manabe Y,Yoshida Y

    更新日期：1990-07-01 00:00:00

  • Ectopic pregnancy associated with the intrauterine device: a study of seventy cases.

    abstract：:Seventy cases of ectopic pregnancy associated with an IUD comprised 10% of all ectopics in a 9 year period. This increased to 15% in the last 19 months as more IUD's were in use. In two thirds of the ectopics the IUD had been in situ more than 1 year. Unusual bleeding and cramping attributed to the IUD obscured the di...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(76)90843-7

    authors： Hallatt JG

    更新日期：1976-07-15 00:00:00

  • Vaginal fetal fibronectin as a predictor of spontaneous preterm delivery after multifetal pregnancy reduction.

    abstract：OBJECTIVE:The study was undertaken to assess the validity of vaginal fetal fibronectin assay as a screening test for spontaneous preterm delivery in asymptomatic patients who have undergone multifetal pregnancy reduction (MFPR). STUDY DESIGN:A historic cohort of 63 patients who underwent MFPR between 10 and 14 weeks o...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2003.07.027

    authors： Roman AS,Rebarber A,Lipkind H,Mulholland J,Minior V,Roshan D

    更新日期：2004-01-01 00:00:00