Reduced umbilical artery prostacyclin formation in complicated pregnancies.

Abstract:

:Prostacyclin synthesis is severely depressed in the umbilical arteries of neonates of mothers with gestational diabetes mellitus, juvenile-onset diabetes mellitus, or preeclamptic symptoms, and of mothers who smoke during pregnancy and diabetic mothers who smoke. The reduced production of prostacyclin might be responsible for an increased abortion rate and a higher rate of intrauterine fetal death because of a decrease in placental perfusion and umbilical blood flow.

journal_name

Am J Obstet Gynecol

authors

Dadak C,Kefalides A,Sinzinger H,Weber G

doi

10.1016/0002-9378(82)90354-4

subject

Has Abstract

pub_date

1982-12-01 00:00:00

pages

792-5

issue

7

eissn

0002-9378

issn

1097-6868

pii

0002-9378(82)90354-4

journal_volume

144

pub_type

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