Abstract:
:Traditionally, assessment of therapy has been judged by the ability of treatment to alleviate symptoms with tolerable side effects or toxicity. In recent years, it has become obvious that more subtle and patient-oriented approaches are urgently needed to evaluate progression of cardiovascular disease and to monitor the efficacy of medical and surgical therapy. Aspects of well-being include physical, emotional, and social status in cardiovascular diseases. While several major assessment methods are available within the social sciences, experiences with the use of comprehensive questionnaires in cardiovascular diseases remains relatively limited. Self-administered questionnaires have been shown to be more reliable than those given by a trained interviewer. Two forms of questionnaires--the visual analogue scale and the one in which patients check off boxes--can be used to quantify symptoms, but the former necessitates more time spent on patient information. Measurements of quality of life can be characterized by the test's validity, reproducibility, and sensitivity. Our information on the sensitivity of life-quality tests is so far scarce, but it has recently been shown that it is possible to discern the effect of various drug treatments in hypertension. The methodology of this assessment needs to be further optimized, and the quality of life parameters need to be correlated with hemodynamics, exercise capacity, morbidity, and mortality.
journal_name
Am Heart Jjournal_title
American heart journalauthors
Storstein Ldoi
10.1016/0002-8703(87)90963-xsubject
Has Abstractpub_date
1987-07-01 00:00:00pages
210-2issue
1 Pt 2eissn
0002-8703issn
1097-6744pii
0002-8703(87)90963-Xjournal_volume
114pub_type
杂志文章abstract::Age is a recognized risk factor for coronary artery disease, but the relationship between age and silent ischemia is not well understood. We analyzed the data from 35 rest/stress radionuclide ventriculography examinations in patients with documented ischemic coronary artery disease who had experienced 1 mm ST segment ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(90)90156-r
更新日期:1990-07-01 00:00:00
abstract::The isovolumic index is a recently described echocardiographic parameter of left ventricular function that is calculated as the ratio between the sum of the time of isovolumic contraction and relaxation divided by the ejection time. Although the individual components of this index may be altered by heart rate and load...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(86)90476-x
更新日期:1986-10-01 00:00:00
abstract::The prevention of major bleeding during percutaneous coronary intervention is one of the most widely discussed and often controversial topics within interventional cardiology. The choice of arterial access should be considered a mechanism for bleeding avoidance, and various strategies have been proposed to prevent or ...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/j.ahj.2015.04.023
更新日期:2015-07-01 00:00:00
abstract::Noninvasive risk assessment in survivors of AMI can effectively subdivide patients into groups with differing risk profiles after hospital discharge, but some patients at risk for late death or recurrent AMI may be incorrectly identified; data from cardiac catheterization and angiography provide complementary and gene...
journal_title:American heart journal
pub_type: 社论
doi:10.1016/0002-8703(91)90747-6
更新日期:1991-02-01 00:00:00
abstract:BACKGROUND:The long-term prognostic significance of elevated cardiac markers in an undifferentiated patient population with chest pain is unknown. METHODS:Serum troponin I (cTnI), creatine kinase-MB (CK-MB), and myoglobin were measured at presentation in 951 consecutive patients evaluated in the emergency department f...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2008.06.020
更新日期:2008-11-01 00:00:00
abstract::Percutaneous balloon mitral valvuloplasty has been shown to be an effective means of reducing mitral valve gradient and increasing mitral valve area in patients with mitral stenosis. Most techniques currently employed for performing this procedure involve delivery of one or two balloon valvuloplasty catheters through ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(05)80279-0
更新日期:1990-03-01 00:00:00
abstract::We studied 56 right ventricular papillary muscles isolated from cats to determine whether the direct mechanical effects of contrast media are due to their pharmacologic action or to the hyperosmolality caused by them. A 10% solution of Renografin-76 abruptly decreased force 22% below control, then slowly increased it ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(84)90550-7
更新日期:1984-07-01 00:00:00
abstract:AIM:The aim of the study was to assess and compare the safety of antiarrhythmic drugs (AADs) in an unselected real-world population of patients with atrial fibrillation (AF). METHODS AND RESULTS:This is a study of all patients with diagnosed AF in the Swedish Patient register who filled a prescription for sotalol, ami...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ahj.2018.06.018
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:Contemporary use of dual antiplatelet therapy and consistency with guideline recommendations in acute coronary syndrome patients undergoing percutaneous coronary intervention (PCI) have not been well characterized. METHODS:The COAPT was a prospective, observational, multicenter, longitudinal study of patien...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2016.07.014
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:The optimal hydration strategy for prevention of contrast-induced acute kidney injury (AKI) remains unknown. The purpose of this meta-analysis is to compare the effectiveness of normal saline (NS) versus sodium bicarbonate hydration (NaHCO(3)) for prevention of contrast-induced AKI. METHODS:We performed a m...
journal_title:American heart journal
pub_type: 杂志文章,meta分析
doi:10.1016/j.ahj.2008.05.014
更新日期:2008-09-01 00:00:00
abstract::The present experiments were conducted on isolated dog hearts to demonstrate that conduction disturbances can be induced in the bundle branches by transection of about 50 per cent of the cross-sectional area of the His bundle on the right or left side. The His bundle, the posterior and anterior divisions of left bundl...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(76)80117-2
更新日期:1976-09-01 00:00:00
abstract::A prospective study examining the relationship between psychological distress and ventricular ectopy was conducted with 125 post-myocardial infarction patients equipped with a transtelephonic ECG monitor. Subjects were subsequently grouped according to the occurrence (n = 59) or nonoccurrence (n = 65) of ventricular a...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0002-8703(88)90246-3
更新日期:1988-07-01 00:00:00
abstract:BACKGROUND:Invasive coronary angiography (ICA) alone fails to accurately select patients with intermediate stenoses who should be treated by percutaneous coronary intervention (PCI). Previous studies have demonstrated the usefulness of fractional flow reserve (FFR) for identifying patients in whom deferring an intended...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2006.11.013
更新日期:2007-03-01 00:00:00
abstract::Mechanisms responsible for the well-documented "protection" against myocardial ischemia and infarction in young women and subsequent loss of protection after menopause remain speculative. One possibility is that gender-related variables (such as endogenous hormone levels or regular loss of stored iron) alter the susce...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(95)90390-9
更新日期:1995-06-01 00:00:00
abstract::Left circumflex coronary blood flow was increased significantly (20 per cent) during stimulation of somatic afferent fibers. The change in CBF was associated with significant increases in heart rate and arterial pressure and significant decrease in coronary vascular resistance. Controlling heart rate or preventing car...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(79)90318-1
更新日期:1979-07-01 00:00:00
abstract::Adequate hydration is recommended for acute ST-elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) to prevent contrast-induced nephropathy (CIN). However, the optimal hydration regimen has not been well established in these high-risk patients. The objective of t...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2015.10.007
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Anginal chest pain without creatine kinase (CK) elevation is frequently observed in the first hours after coronary stenting. Possible causes of ischemic episodes are microembolism, side branch occlusion, coronary vasospasm, and disturbances of microvascular circulation. In a prospective, double-blind, random...
journal_title:American heart journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0002-8703(00)90306-5
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:We assessed left atrial function in normal subjects and in patients with hypertrophic cardiomyopathy (HCM) by using Doppler echocardiography at the supine position and after sudden standing. METHODS AND RESULTS:Twenty-seven patients with hypertrophic obstructive cardiomyopathy (HOCM), 17 patients with HCM, ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(98)70153-x
更新日期:1998-12-01 00:00:00
abstract:BACKGROUND:National registries are advocated as instrumental to the solution of rarity-related problems for patients with hypertrophic cardiomyopathy (HCM), including limited access to advanced treatment options. Thus, an Italian Registry for HCM was created to assess the clinical profile and the level of care nationwi...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2005.01.005
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND:Multidisciplinary disease management programs (MDMP) have demonstrated reduced hospitalizations in motivated pretransplant heart failure populations, but little is known about their effectiveness in largely indigent patients who are not transplant candidates. METHODS AND RESULTS:We studied 35 patients with ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2001.111956
更新日期:2001-02-01 00:00:00
abstract::Coronary heart disease is the single largest cause of morbidity and mortality in the United States. The link between elevated low-density lipoprotein cholesterol (LDL-C) levels and coronary heart disease (CHD) has been clearly established. However, triglycerides (TG) are increasingly believed to be independently assoc...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/j.ahj.2004.03.037
更新日期:2004-08-01 00:00:00
abstract:BACKGROUND:Little is known about the management of elderly patients with congestive heart failure (CHF) although they represent the majority of the CHF population. Therefore, the TIME-CHF study was set up (1) to evaluate the medical management of very old patients (> or = 75 years) with CHF compared with younger patien...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2005.10.022
更新日期:2006-05-01 00:00:00
abstract::Reperfusion therapy has lowered the mortality in patients suffering acute myocardial infarction. Failure to reperfuse is associated with significantly higher risk of short- and long-term mortality. Detection of reperfusion is thus important. In a prospective pilot study, we used continuous on-line computerized vectorc...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(91)90455-q
更新日期:1991-10-01 00:00:00
abstract:BACKGROUND:Traditional risk factors predict the 10-year risk of developing coronary heart disease (CHD). Underlying risk factors like physical inactivity, obesity (BMI >30 kg/m2), and family history of premature CHD are independently associated with CHD. High burden of coronary artery calcification (CAC) on electron be...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2004.05.033
更新日期:2004-11-01 00:00:00
abstract::To evaluate the antiischemic effects of intravenous milrinone, 20 patients with angiographically proved coronary artery disease and stable angina were studied at rest and during exercise under control conditions and after an intravenous loading injection of milrinone (50 micrograms/kg/10 min) followed by an infusion w...
journal_title:American heart journal
pub_type: 临床试验,杂志文章
doi:10.1016/0002-8703(91)90835-6
更新日期:1991-06-01 00:00:00
abstract:BACKGROUND:Diabetes mellitus and impaired glucose metabolism are associated with increased risk for cardiovascular disease (CVD). However, it is still not clear whether glucose levels can predict CVD risk among patients without diabetes. The primary aim of this study is to assess whether normoglycemic fasting plasma gl...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2012.03.023
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:A strategy using coronary artery calcium (CAC) screening to refine coronary heart disease risk assessment in moderately high risk (MHR) subjects (10-year risk 10%-20%) has been suggested. The potential impact of this strategy is unknown. METHODS:Coronary artery calcium screening strategies focused on MHR su...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2009.03.018
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:Although geographic variation in the treatment of acute myocardial infarction (AMI) has been recognized, the impact of evidence-based international treatment guidelines on such variation is unclear. We sought to characterize resource use and cost of initial hospitalization for AMI in 9 countries and compare ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2005.02.028
更新日期:2006-01-01 00:00:00
abstract::Left ventricular mass (LVM) measurements made by the truncated ellipsoid algorithm from clinical two-dimensional echocardiograms (2DE) were compared to autopsy weights in 37 patients. All six 2DE instruments were calibrated with an ultrasound phantom to standardize LVM measurements. Measurements were made by an experi...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(89)90083-5
更新日期:1989-07-01 00:00:00
abstract:BACKGROUND:In regional systems of ST-segment elevation myocardial infarction (STEMI) care, patients presenting to hospitals without percutaneous coronary intervention (PCI) are transferred to PCI-capable hospitals for primary PCI. Repatriation, a practice whereby such patients are transferred back to non-PCI referral h...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2016.04.017
更新日期:2016-07-01 00:00:00