The cellular electrophysiologic changes induced by ablation: comparison between argon laser photoablation and high-energy electrical ablation.

abstract：BACKGROUND:The clinical significance of the interaction between clopidogrel and proton pump inhibitors (PPIs) remains unclear. METHODS AND RESULTS:We examined the relationship between PPI use and 1-year cardiovascular events (cardiovascular death, myocardial infarction, or stroke) in patients with acute coronary syndr...

journal_title：Circulation

authors： Goodman SG,Clare R,Pieper KS,Nicolau JC,Storey RF,Cantor WJ,Mahaffey KW,Angiolillo DJ,Husted S,Cannon CP,James SK,Kilhamn J,Steg PG,Harrington RA,Wallentin L,Platelet Inhibition and Patient Outcomes Trial Investigators.

更新日期：2012-02-28 00:00:00

abstract：BACKGROUND:Mutations in the gene G4.5 result in a wide spectrum of severe infantile cardiomyopathic phenotypes, including isolated left ventricular noncompaction (LVNC), as well as Barth syndrome (BTHS) with dilated cardiomyopathy (DCM). The purpose of this study was to investigate patients with LVNC or BTHS for mutati...

journal_title：Circulation

authors： Ichida F,Tsubata S,Bowles KR,Haneda N,Uese K,Miyawaki T,Dreyer WJ,Messina J,Li H,Bowles NE,Towbin JA

更新日期：2001-03-06 00:00:00

abstract：BACKGROUND:During the 1980s, mortality from coronary artery disease (CAD) decreased markedly in the United States. This raises the question of whether a parallel decrease occurred in excess mortality due to CAD in patients undergoing surgical correction of valvular regurgitation. METHODS AND RESULTS:Survival of 752 pa...

journal_title：Circulation

authors： Tribouilloy CM,Enriquez-Sarano M,Schaff HV,Orszulak TA,Fett SL,Bailey KR,Tajik AJ,Frye RL

更新日期：1998-11-10 00:00:00

abstract：BACKGROUND:Giant cell myocarditis (GCM) typically causes fulminant heart failure, arrhythmias, or heart block, necessitating aggressive immunosuppression, ventricular assist device insertion, or cardiac transplantation. We describe a novel variant of GCM, primarily involving the atria, that displays distinctive clinica...

journal_title：Circulation

authors： Larsen BT,Maleszewski JJ,Edwards WD,Cooper LT Jr,Sobonya RE,Thompson VE,Duckett SG,Peebles CR,Simpson IA,Tazelaar HD

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Although insulin resistance has been implicated in the pathogenesis of left ventricular (LV) hypertrophy, previous studies have yielded inconsistent results and are limited by referral bias. METHODS AND RESULTS:We examined the relations between echocardiographic LV measurements and glucose tolerance status ...

journal_title：Circulation

authors： Rutter MK,Parise H,Benjamin EJ,Levy D,Larson MG,Meigs JB,Nesto RW,Wilson PW,Vasan RS

更新日期：2003-01-28 00:00:00

abstract：:Current imaging modalities can provide only a qualitative or semiquantitative measure of the severity of aortic regurgitation. Ultrafast computed tomography (CT) has the capability of rapid imaging (17 frames/sec) coupled with high spatial resolution (1.5 mm2). Eight millimeter thick images can be acquired to interrog...

journal_title：Circulation

authors： Reiter SJ,Rumberger JA,Stanford W,Marcus ML

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND:Aortic valve-preserving procedures have resulted in excellent outcomes in selected patients, particularly those with normal aortic valve leaflets and dilated aortic roots. However, several congenital heart lesions are associated with abnormal aortic valve leaflets. The long-term results of aortic valve repai...

journal_title：Circulation

authors： Rao V,Van Arsdell GS,David TE,Azakie A,Williams WG

更新日期：2000-11-07 00:00:00

abstract：:To determine whether cardiac transplant rejection can be detected noninvasively with indium-111 (111In)-labeled lymphocytes, we studied 11 dogs with thoracic heterotopic cardiac transplants without immunosuppression and five dogs with transplants treated with cyclosporine (10 mg/kg/day) and prednisone (1 mg/kg/day). A...

journal_title：Circulation

authors： Eisen HJ,Eisenberg SB,Saffitz JE,Bolman RM 3rd,Sobel BE,Bergmann SR

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND:In the experimental setting, it has been demonstrated that preconditioning myocardium before prolonged occlusion with brief ischemic episodes affords substantial protection to the cells by delaying lethal injury, thereby limiting infarct size. Whether the same occurs in humans remains unknown. METHODS AND R...

journal_title：Circulation

authors： Ottani F,Galvani M,Ferrini D,Sorbello F,Limonetti P,Pantoli D,Rusticali F

更新日期：1995-01-15 00:00:00

abstract：BACKGROUND:We have reported that there is a limitation of exercise capacity in mice with defects in the expression of endothelial nitric oxide (NO) synthase, which is associated with a greater increase in whole-body oxygen consumption (VO2). We hypothesized that in states in which superoxide anion (O2-) is increased, e...

journal_title：Circulation

authors： Kinugawa S,Wang Z,Kaminski PM,Wolin MS,Edwards JG,Kaley G,Hintze TH

更新日期：2005-03-29 00:00:00

abstract：BACKGROUND:Abnormal vascular reactivity represents a fundamental disturbance in vascular biology with the development of atherosclerosis. Because endothelial vasodilator function plays a pivotal role in controlling vasomotor tone, we hypothesized that atherosclerotic wall thickening might directly interfere with defici...

journal_title：Circulation

authors： Zeiher AM,Schächlinger V,Hohnloser SH,Saurbier B,Just H

更新日期：1994-06-01 00:00:00

abstract：:Electrophysiologic studies were performed in 28 patients with documented atrioventricular (AV) nodal reentrant supraventricular tachycardia (SVT) to investigate the presence of AV nodal tissue situated between the tachycardia circuit and both the atrium (upper common pathway, UCP) and the His bundle (lower common path...

journal_title：Circulation

authors： Miller JM,Rosenthal ME,Vassallo JA,Josephson ME

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND:Fibrinogen binding to the active conformation of the alpha(IIb)beta(3) integrin receptor (glycoprotein IIb/IIIa) and cytoskeletal reorganization are important events in platelet function. Tyrosine phosphorylation of platelet proteins plays an essential role in platelet signal transduction pathways. We studie...

journal_title：Circulation

authors： Santos MT,Moscardó A,Vallés J,Martínez M,Piñón M,Aznar J,Broekman MJ,Marcus AJ

更新日期：2000-10-17 00:00:00

abstract：:Venous thromboembolism (VTE) is a major preventable disease that affects hospitalized inpatients. Risk stratification and prophylactic measures have good evidence supporting their use, but multiple reasons exist that prevent full adoption, compliance, and efficacy that may underlie the persistence of VTE over the past...

journal_title：Circulation

authors： Henke PK,Kahn SR,Pannucci CJ,Secemksy EA,Evans NS,Khorana AA,Creager MA,Pradhan AD,American Heart Association Advocacy Coordinating Committee.

更新日期：2020-06-16 00:00:00

abstract：:We have studied the effects of cardioplegic solution (CS) on angiographic and histologic anatomy of bilateral vein grafts interposed into the carotid arteries of 10 dogs for up to 1 year. One vein (exp) was infused with cardioplegic solution (pH 7.7, K + 25 mEq/l, temperature 12 degrees C) every 15 min four times at p...

journal_title：Circulation

authors： Singh AK,Capone RJ,O'Shea P,Karlson KE

更新日期：1983-09-01 00:00:00

abstract：:We quantitated the growth patterns of the normal fetal heart and the right and left ventricles from postmortem hearts obtained from 55 spontaneously aborted human fetuses from the completion of cardiogenesis to term. Fetal gestational age was assessed by menstrual history of the mother, crown-rump length, head circumf...

journal_title：Circulation

authors： St John Sutton MG,Raichlen JS,Reichek N,Huff DS

更新日期：1984-12-01 00:00:00

abstract：:We studied the inferior vena cava (IVC) as an index of right-heart function in 111 patients. A two-dimensional echocardiographic sector was used to visualize the IVC, and its M-mode cursor was used to generate a time-motion record of the IVC size and pulsation. Normal subjects had a small presystolic A wave (less than...

journal_title：Circulation

authors： Mintz GS,Kotler MN,Parry WR,Iskandrian AS,Kane SA

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:Cardiac parasympathetic nerves run alongside the superior vena cava (SVC) and accumulate particularly epicardially adjacent to the orifice of the coronary sinus (CS). In animals, these nerves can be electrically stimulated inside the SVC or CS, which results in negative chronotropic/dromotropic effects and n...

journal_title：Circulation

authors： Schauerte P,Mischke K,Plisiene J,Waldmann M,Zarse M,Stellbrink C,Schimpf T,Knackstedt C,Sinha A,Hanrath P

更新日期：2001-11-13 00:00:00

abstract：:Total anomalous pulmonary venous connection (TAPVC) is a rare cardiac congenital abnormality which usually results in death in infancy or early childhood. We describe a 52-year-old man with TAPVC and severe calcific pulmonic stenosis. Both diagnoses were suspected clinically and from the chest X-ray. Cardiac catheteri...

journal_title：Circulation

authors： Pastore JO,Akins CW,Zir LM,Buckley MJ,Dinsmore RE

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:The hypoxia-inducible transcription factor (HIF) subunits are destabilized via the O(2)-dependent prolyl hydroxylase domain proteins (PHD1, PHD2, and PHD3). We investigated whether inhibition of PHDs via upregulating HIF might promote postischemic neovascularization. METHODS AND RESULTS:Mice with right femo...

journal_title：Circulation

authors： Loinard C,Ginouvès A,Vilar J,Cochain C,Zouggari Y,Recalde A,Duriez M,Lévy BI,Pouysségur J,Berra E,Silvestre JS

更新日期：2009-07-07 00:00:00

abstract：BACKGROUND:Depressed ventricular performance and neurohormonal activation are key pathophysiological features of congestive heart failure (CHF). Although angiotensin-converting enzyme inhibitors and beta-adrenoceptor blockers exert beneficial effects in CHF, mortality remains unacceptably high, and the development of f...

journal_title：Circulation

authors： Kaye DM,Mansfield D,Aggarwal A,Naughton MT,Esler MD

更新日期：2001-05-15 00:00:00

abstract：BACKGROUND:Platelet aggregation plays a critical role in myocardial infarction and stroke; however, the role of platelet secretion in atherosclerotic vascular disease is poorly understood. Therefore, we examined the hypothesis that platelet dense-granule secretion modulates thrombosis, inflammation, and atherosclerotic...

journal_title：Circulation

authors： King SM,McNamee RA,Houng AK,Patel R,Brands M,Reed GL

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Two types of ischemia, pacing-induced and coronary occlusion-induced, have different effects on left ventricular diastolic properties. During pacing-induced ischemia, the diastolic pressure-volume relation is said to shift upward, whereas during coronary occlusion, it is said to shift rightward or downward. ...

journal_title：Circulation

authors： Takano H,Glantz SA

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:The aim of the study was to establish the influence of proximal coronary artery atheroma and smoking habit on the stimulated release of tissue plasminogen activator (tPA) from the heart. METHODS AND RESULTS:After diagnostic coronary angiography in 25 patients, the left anterior descending coronary artery (L...

journal_title：Circulation

authors： Newby DE,McLeod AL,Uren NG,Flint L,Ludlam CA,Webb DJ,Fox KA,Boon NA

更新日期：2001-04-17 00:00:00

abstract：:We evaluated the accuracy of the recently reported technique of estimating intraventricular volume by measurement of intracavitary electrical conductance in six isolated, ejecting, canine left ventricles. Left ventricular volumes were measured directly by a previously validated servosystem that employed an electrocond...

journal_title：Circulation

authors： Burkhoff D,van der Velde E,Kass D,Baan J,Maughan WL,Sagawa K

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:Oxygen administration is currently used in clinical medicine to improve peripheral oxygen delivery to tissues threatened by ischemia. However, conflicting results have been reported on the effects of oxygen in ischemic areas. This study was aimed at investigating the effects of 40% oxygen inhalation on the s...

journal_title：Circulation

authors： Bongard O,Bounameaux H,Fagrell B

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:The association of anticardiolipin (aCL) antibodies with coronary artery disease has been shown in several studies but remains controversial. We evaluated the association of aCL and anti-beta(2)-glycoprotein I (abeta(2)GPI) antibodies with the risk of recurrent cardiac events in postinfarction patients. MET...

journal_title：Circulation

authors： Bili A,Moss AJ,Francis CW,Zareba W,Watelet LF,Sanz I

更新日期：2000-09-12 00:00:00

abstract：BACKGROUND:We examined the associations of a range of parental and early life characteristics with systolic blood pressure at 5 years of age. METHODS AND RESULTS:Information from 3864 children who were followed up prospectively from their mother's first antenatal clinic assessment was used. Maternal age, body mass ind...

journal_title：Circulation

authors： Lawlor DA,Najman JM,Sterne J,Williams GM,Ebrahim S,Davey Smith G

更新日期：2004-10-19 00:00:00

abstract：BACKGROUND:Repeated brief episodes of myocardial ischemia performed by mechanical clamping of a coronary artery "precondition" the heart and reduce infarct size after a subsequent sustained ischemia. It is not known, however, whether spontaneous episodes of transient ischemia caused by formation of platelet thrombi, wh...

journal_title：Circulation

authors： Ovize M,Kloner RA,Hale SL,Przyklenk K

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Cellular transplantation is emerging as a promising strategy for the treatment of postinfarction ventricular dysfunction. Whether its beneficial effects can be extended to other cardiomyopathies remains an unexplored question. We evaluated the histological and functional effects of simultaneous autologous tr...

journal_title：Circulation

authors： Guarita-Souza LC,Carvalho KA,Woitowicz V,Rebelatto C,Senegaglia A,Hansen P,Miyague N,Francisco JC,Olandoski M,Faria-Neto JR,Brofman P

更新日期：2006-07-04 00:00:00