The effects of methylamphetamine on mood and appetite in depressed patients: a placebo-controlled study.

Abstract:

:Methylamphetamine given intravenously as a single 15 mg dose led to a pronounced elevation of mood in 7 out of 21 depressed patients compared to a control injection of sterile water administered on another occasion in random order under double-blind conditions. All 7 responders experienced an increase of VAS self-ratings of hunger in contrast to what has been observed in normal subjects who show a decrease in hunger after amphetamine. The implications of these findings are discussed in the light of monoamine theories of depression and appetite control.

authors

Cookson J,Silverstone T

doi

10.1097/00004850-198604000-00004

subject

Has Abstract

pub_date

1986-04-01 00:00:00

pages

127-33

issue

2

eissn

0268-1315

issn

1473-5857

journal_volume

1

pub_type

临床试验,杂志文章,随机对照试验
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