当前位置： SCI文献检索 > AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY期刊下所有文献 > Determination of estrogen and androgen receptors in Trichomonas vaginalis and the effects of antihormones.

Determination of estrogen and androgen receptors in Trichomonas vaginalis and the effects of antihormones.

Abstract：

:Trichomonas vaginalis, a common genital pathogen, was found to possess both specific estrogen and specific androgen receptors. These 4.3 S macromolecules were proteinaceous in nature. Both metronidazole-resistant and metronidazole-sensitive strains possessed both types of sex hormone-binding proteins. The estrogen receptor binding was competitively inhibited by the antiestrogen tamoxifen citrate, and the androgen binding was competitively inhibited by the antiandrogen cyoctol. The presence of these specific receptors may allow the use of hormonal and antihormonal manipulation in the treatment of infections caused by these organisms.

journal_name

Am J Obstet Gynecol

journal_title

American journal of obstetrics and gynecology

authors

Ford LC,Hammill HA,DeLange RJ,Bruckner DA,Suzuki-Chavez F,Mickus KL,Lebherz TB

doi

10.1016/0002-9378(87)90122-0

subject

Has Abstract

pub_date

1987-05-01 00:00:00

pages

1119-21

issue

5

eissn

0002-9378

issn

1097-6868

pii

0002-9378(87)90122-0

journal_volume

156

pub_type

杂志文章

相关文献

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY文献大全
  • A randomized trial that compared oral cefixime and intramuscular ceftriaxone for the treatment of gonorrhea in pregnancy.

    abstract：OBJECTIVE:The purpose of this study was to evaluate prospectively the Centers for Disease Control recommendations for the treatment of gonococcal infection in pregnancy. STUDY DESIGN:One hundred sixty-one women who were referred with probable endocervical gonorrhea underwent pretreatment endocervical, anal, and oral c...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1067/mob.2001.117662

    authors： Ramus RM,Sheffield JS,Mayfield JA,Wendel GD Jr

    更新日期：2001-09-01 00:00:00

  • Characteristics and management of pregnancy in women with genital herpes simplex virus infection.

    abstract：:The natural history of genital herpes simplex virus (HSV) infections was investigated in 83 pregnancies in 78 women, and the information was used to determine the need for cesarean section in these women. We studied 163 recurrent episodes with HSV cultures from the cervix and from vulvar lesions every 1 to 3 days. Cer...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(83)90679-8

    authors： Harger JH,Pazin GJ,Armstrong JA,Breinig MC,Ho M

    更新日期：1983-04-01 00:00:00

  • Insulin-requiring diabetes in pregnancy: a randomized trial of active induction of labor and expectant management.

    abstract：OBJECTIVE:Our purpose was to assess whether a program of expectant management of uncomplicated pregnancies in mothers with insulin-requiring gestational or pregestational class B reduces the incidence of cesarean birth. STUDY DESIGN:Two hundred women with uncomplicated, insulin-requiring diabetes at 38 weeks' gestatio...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0002-9378(93)90631-r

    authors： Kjos SL,Henry OA,Montoro M,Buchanan TA,Mestman JH

    更新日期：1993-09-01 00:00:00

  • Severe maternal morbidity and comorbid risk in hospitals performing

    abstract：BACKGROUND:While research has demonstrated increasing risk for severe maternal morbidity in the United States, risk at lower volume hospitals remains poorly characterized. More than half of all obstetric units in the United States perform <1000 deliveries per year and improving care at these hospitals may be critical t...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2016.10.029

    authors： Hehir MP,Ananth CV,Wright JD,Siddiq Z,D'Alton ME,Friedman AM

    更新日期：2017-02-01 00:00:00

  • The diagnosis of polycystic ovary syndrome in adolescents.

    abstract：:In women, the definition of polycystic ovary syndrome (PCOS) has become broad and includes several possible phenotypes. Because several features of PCOS may be in evolution in adolescents, we suggest that only firm criteria should be used to make a diagnosis of PCOS during adolescence. Hyperandrogenism, oligomenorrhea...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ajog.2010.03.008

    authors： Carmina E,Oberfield SE,Lobo RA

    更新日期：2010-09-01 00:00:00

  • Functional significance of the zonal morphologic differences in the normal human placenta. A morphometric study.

    abstract：:Previous investigations have shown that the human placenta is a complex organ with different zones, each with a unique morphology. These zonal morphologic difference have been related to a probable blood PO2 gradient operating in the intervillous space. This study describes zonal variations in the vertical plane of th...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(78)90007-8

    authors： Teasdale F

    更新日期：1978-04-01 00:00:00

  • Effects of inhibition of prostaglandin synthesis on flow and composition of fetal urine, lung liquid, and swallowed fluid in sheep.

    abstract：OBJECTIVE:Our aim was to determine the effects of blocking prostaglandin synthesis, by infusion of indomethacin into the fetal circulation, on factors regulating amniotic fluid volume and on plasma composition in the mother and fetus. STUDY DESIGN:Indomethacin was administered to fetal sheep during 8 hours at 124.0 +/...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(94)70406-6

    authors： Wlodek ME,Harding R,Thorburn GD

    更新日期：1994-01-01 00:00:00

  • The advanced life support in obstetrics course as an orientation tool for obstetrics and gynecology residents.

    abstract：OBJECTIVE:This study was undertaken to assess the utility of the Advanced Life Support in Obstetrics Course for obstetrics/gynecology first-year residents by triangulating pretest and posttest scores on written test of knowledge by interns, with qualitative surveys by residents, and faculty. STUDY DESIGN:Obstetrics/gy...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2006.10.912

    authors： Dauphin-McKenzie N,Celestin MJ,Brown D,González-Quintero VH

    更新日期：2007-05-01 00:00:00

  • Doppler velocimetry and fetal heart rate studies in nephropathic diabetics.

    abstract：OBJECTIVES:Our objectives were to determine in pregnancies complicated by diabetic nephropathy (1) if impedance to flow in the uterine and umbilical arteries is normal and (2) if these fetuses are hypoxemic and acidemic and if they have decreased fetal heart rate variation and Doppler blood flow redistribution. STUDY ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(11)91704-9

    authors： Salvesen DR,Higueras MT,Brudenell JM,Drury PL,Nicolaides KH

    更新日期：1992-11-01 00:00:00

  • Defining the relationship between obstetricians and maternal-fetal medicine specialists.

    abstract：OBJECTIVE:The purpose of this study was to determine how frequently general obstetricians refer pregnant patients to maternal-fetal medicine specialists in the presence of the clinical indications specified as appropriate for referral or consultation by the 1996 statement of the Society of Perinatal Obstetricians. STU...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2001.117348

    authors： Vintzileos AM,Ananth CV,Smulian JC,Scorza WE,Knuppel RA

    更新日期：2001-10-01 00:00:00

  • Do alterations in vaginal dimensions after reconstructive pelvic surgeries affect the risk for dyspareunia?

    abstract：OBJECTIVE:The purpose of this study was to determine whether changes in vaginal dimensions after transvaginal reconstructive pelvic surgeries affect the risk for postoperative dyspareunia. STUDY DESIGN:Charts of all sexually active patients who underwent transvaginal reconstructive pelvic surgeries in our institution ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2004.10.628

    authors： Abramov Y,Gandhi S,Botros SM,Goldberg RP,Sherman W,Rurak M,Sand PK

    更新日期：2005-05-01 00:00:00

  • Gene expression profiling of mid to late secretory phase endometrial biopsies from women with menstrual complaint.

    abstract：OBJECTIVE:The purpose of this study was to test whether a quantitative high-throughput molecular screen can be used to probe human endometrium and initiate the development of molecular diagnostic tools with potential for identification of therapeutic targets in women with menstrual complaints. STUDY DESIGN:Endometrium...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2006.05.002

    authors： Critchley HO,Robertson KA,Forster T,Henderson TA,Williams AR,Ghazal P

    更新日期：2006-08-01 00:00:00

  • Long-term outcome after exercising throughout pregnancy: fitness and cardiovascular risk.

    abstract：OBJECTIVE:The objective of the study was to test the null hypothesis that continuing vigorous weight-bearing exercise throughout pregnancy has no discernible long-term effect on indices of fitness and/or cardiovascular risk. STUDY DESIGN:This was a follow-up observational study of the fitness and cardiovascular risk p...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2008.05.006

    authors： Clapp JF 3rd

    更新日期：2008-11-01 00:00:00

  • Type and screen: a safe and effective preoperative blood ordering policy with emphasis on its use in obstetrics and gynecology.

    abstract：:In September, 1979, the Transfusion Committee at the University of Texas Medical Branch in Galveston implemented a preoperative blood ordering policy of type and screen (TS) for selected surgical procedures. During the first year in which this policy was in force, 2,301 TS requests were received, most of them for pati...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(82)90762-1

    authors： Patten E,Alperin JB

    更新日期：1982-03-01 00:00:00

  • Night sweats, sleep disturbance, and depression associated with diminished libido in late menopausal transition and early postmenopause: baseline data from the Herbal Alternatives for Menopause Trial (HALT).

    abstract：OBJECTIVE:The objective of the study was to evaluate the association of depression, sleep disturbance, and menopausal symptoms with diminished libido. STUDY DESIGN:Data from a 2001-2002 baseline survey of 341 peri- and postmenopausal women, aged 45-55 years, participating in a randomized trial, was analyzed. Eligibili...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2007.03.008

    authors： Reed SD,Newton KM,LaCroix AZ,Grothaus LC,Ehrlich K

    更新日期：2007-06-01 00:00:00

  • Effect of a previous pregnancy on vascular function in endothelial nitric oxide synthase 3 knockout mice.

    abstract：OBJECTIVE:Nitric oxide deficiency has been implicated in adverse pregnancy outcomes. Mice that lack endothelial nitric oxide synthase (NOS3) have abnormal in vitro vascular reactivity. Our objective was to assess the effect of a previous pregnancy on the abnormal vascular function of NOS3 knockout mice. STUDY DESIGN:C...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2007.06.062

    authors： Ghulmiyyah LM,Tamayo E,Clark SM,Hankins GD,Anderson GD,Saade GR,Longo M

    更新日期：2007-09-01 00:00:00

  • Quantitation of uterine activity preceding preterm, term, and postterm labor.

    abstract：:To assess uterine activity before labor in patients delivering preterm, at term, and postterm, the maximum spontaneous contraction frequency per 10-minute window during the initial portion of antepartum fetal heart rate monitoring was analyzed. Patients with multiple gestation, third trimester bleeding, polyhydramnios...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(88)90353-5

    authors： Nageotte MP,Dorchester W,Porto M,Keegan KA Jr,Freeman RK

    更新日期：1988-06-01 00:00:00

  • Effect of administration route and estrogen manipulation on endometrial uptake of Photofrin porfimer sodium.

    abstract：OBJECTIVE:Our purpose was to evaluate the influence of the route of drug administration and target tissue vascularity on the distribution of a photosensitizer, Photofrin porfimer sodium, in the uterus. STUDY DESIGN:The study was divided in two phases. In phase I 80 mature female rats were hormonally suppressed and the...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(93)90517-m

    authors： Chapman JA,Tadir Y,Tromberg BJ,Yu K,Manetta A,Sun CH,Berns MW

    更新日期：1993-02-01 00:00:00

  • Where have all the trisomies gone?

    abstract：:Providing reliable prenatal screening performance estimates is critical for patient counseling and policy-making. Women who choose prenatal screening for aneuploidy are likely to be concerned not only with the common aneuploidies but with all causes of intellectual disability and serious birth defects. Sequential pren...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 社论

    doi：10.1016/j.ajog.2016.06.046

    authors： Palomaki GE,Lambert-Messerlian GM,Haddow JE

    更新日期：2016-11-01 00:00:00

  • Elevated circulating concentrations of platelet activating factor in preeclampsia.

    abstract：OBJECTIVE:The aim of this study was to determine whether any association exists between preeclampsia and circulating platelet activating factor levels. STUDY DESIGN:We performed a cross-sectional observational study of circulating platelet activating factor concentrations in nonpregnant women, normotensive pregnant wo...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2000.108894

    authors： Rowland BL,Vermillion ST,Roudebush WE

    更新日期：2000-10-01 00:00:00

  • External cephalic version beginning at 34 weeks' gestation versus 37 weeks' gestation: a randomized multicenter trial.

    abstract：OBJECTIVE:In about 3% to 4% of all pregnancies at term, the fetal presentation will be noncephalic. External cephalic version (ECV) at term has been shown to decrease the rate of noncephalic presentation at birth and to decrease the rate of cesarean section associated with breech presentation. However, success rates fo...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1067/mob.2003.442

    authors： Hutton EK,Kaufman K,Hodnett E,Amankwah K,Hewson SA,McKay D,Szalai JP,Hannah ME

    更新日期：2003-07-01 00:00:00

  • First-trimester uterine scar assessment by transvaginal ultrasound.

    abstract：OBJECTIVE:The objective of the study was to describe the assessment of lower segment uterine scar (LSCS) by transvaginal ultrasound (TVUS) during a first-trimester scan. STUDY DESIGN:Patients with a history of LSCS were prospectively enrolled over a 6 month period. Four groups were defined: type 1A, thin scar within c...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.ajog.2011.06.104

    authors： Stirnemann JJ,Chalouhi GE,Forner S,Saidji Y,Salomon LJ,Bernard JP,Ville Y

    更新日期：2011-12-01 00:00:00

  • Progression of ultrasound findings of fetal syphilis after maternal treatment.

    abstract：OBJECTIVE:The purpose of this study was to evaluate ultrasound findings of fetal syphilis and to describe their progression after maternal treatment. STUDY DESIGN:This was a retrospective cohort study from September 1981 to June 2011 of seropositive women after 18 weeks of gestation who had an ultrasound before treatm...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2014.05.049

    authors： Rac MW,Bryant SN,McIntire DD,Cantey JB,Twickler DM,Wendel GD Jr,Sheffield JS

    更新日期：2014-10-01 00:00:00

  • Correlation of the effects of dexamethasone administration on urinary 17-ketosteroid and serum androgen levels in patients with hirsutism.

    abstract：:Total 24 hour urinary 17-ketosteroid and serum testosterone (T), androstenedione (delta), dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DS), and cortisol levels were measured before and during four days of dexamethasone administration in 28 hirsute patients and 10 women with normal ovulatory cycles. B...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(77)90560-9

    authors： Judd HL,McPherson RA,Rakoff JS,Yen SS

    更新日期：1977-06-15 00:00:00

  • Rh isoimmunization: a 24 year experience at Duke University Medical Center.

    abstract：:A retrospective analysis was made of Rh-sensitized patients delivered of their babies at Duke University Medical Center during a 24 year period. Records of 202 obstetric patients representing 280 sensitized pregnancies from a pool of 39,910 deliveries were analyzed for past obstetric history, blood group information, ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(81)90083-1

    authors： Gall SA,Miller JM Jr

    更新日期：1981-08-15 00:00:00

  • Effect of hydatidiform molar vesicular fluid on blood coagulation.

    abstract：:The effect of fluids from both complete and partial hydatidiform moles on blood coagulation was determined. Coagulation was evaluated with use of the one-stage prothrombin time and the activated partial thromboplastin time. These studies demonstrated that the fluids shortened the activated partial thromboplastin time ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(85)80263-5

    authors： Kaplan SS,Szulman AE,Surti U

    更新日期：1985-11-15 00:00:00

  • Long-term magnesium sulfate treatment as protection against hypoxic-ischemic brain injury in seven-day-old rats.

    abstract：OBJECTIVE:Our purpose was to study the effects of long-term treatment with magnesium sulfate on hypoxic-ischemic brain damage in newborn rats. STUDY DESIGN:Seven-day-old rat pups (n = 120) were exposed to unilateral carotid artery ligation and 2 hours of hypoxia (8% oxygen in 92% nitrogen). Neuronal loss was evaluated...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2001.108343

    authors： Sameshima H,Ikenoue T

    更新日期：2001-01-01 00:00:00

  • Detection of genes that are differentially expressed during mouse embryogenesis by genetic trapping strategies.

    abstract：OBJECTIVE:Our objective was to identify novel genes that are expressed in temporally and spatially restricted patterns during mouse embryonic development and organogenesis. STUDY DESIGN:Two genetic trapping reporter constructs that lack transcriptional regulatory sequences were introduced independently into transcript...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(93)90643-w

    authors： Johnson MD,Mahon KA

    更新日期：1993-09-01 00:00:00

  • Elevated circulating thrombomodulin in severe preeclampsia.

    abstract：:A relationship between serum thrombomodulin and preeclampsia was investigated. In women with severely preeclamptic pregnancies, serum thrombomodulin levels were found to be significantly elevated as compared with those of matched control subjects (p < 0.005). Serum thrombomodulin levels correlated positively with seru...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(93)90151-8

    authors： Hsu CD,Iriye B,Johnson TR,Witter FR,Hong SF,Chan DW

    更新日期：1993-07-01 00:00:00

  • The burden of illness of severe nausea and vomiting of pregnancy in the United States.

    abstract：OBJECTIVE:Our purpose was to determine the extent to which nausea and vomiting of pregnancy affects a woman's quality of life (QOL), ability to function, and health care resource use. STUDY DESIGN:We conducted an observational, multicenter, prospective cohort study by gathering data on the symptoms, QOL, and health ca...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,多中心研究

    doi：10.1067/mob.2002.122605

    authors： Attard CL,Kohli MA,Coleman S,Bradley C,Hux M,Atanackovic G,Torrance GW

    更新日期：2002-05-01 00:00:00