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Auto-anti-Jka in Evans' syndrome with negative direct antiglobulin test.

Abstract：

:A patient presented with haemolytic anaemia and a negative direct antiglobulin test (DAT), and was found to have an IgG antibody with anti-Jka specificity in his serum. His red cells were typed as Jk(a-b+). Later he developed idiopathic thrombocytopenic purpura (ITP), and had a positive DAT due to anti-Jka bound to his red cells, which now typed as Jk(a+b+). Family studies suggested that the patient's true type was Jk(a+b+). Splenectomy and immunosuppression were required to treat the thrombocytopenia. The autoanti-Jka was no longer detectable following therapy.

journal_name

Br J Haematol

journal_title

British journal of haematology

authors

Ganly PS,Laffan MA,Owen I,Hows JM

doi

10.1111/j.1365-2141.1988.tb02411.x

subject

Has Abstract

pub_date

1988-08-01 00:00:00

pages

537-9

issue

4

eissn

0007-1048

issn

1365-2141

journal_volume

69

pub_type

杂志文章

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