Carbamazepine in rapid cycling bipolar affective disorder.

Abstract:

:Eighteen patients with rapid cycling bipolar affective disorder were recruited for an open trial of carbamazepine. Of these patients all but 2 had been resistant to lithium prophylaxis. Twelve of the patients were able to complete at least 6 months on carbamazepine. Of these 12 patients, 2 had a complete remission of their affective disorders on carbamazepine alone, 2 completely responded to combined lithium and carbamazepine treatment, 3 had a slight beneficial effect from the drug, and for the other 5 patients carbamazepine was of no therapeutic benefit. This suggests that, while carbamazepine is effective for some rapid cycling patients, for the majority alternative treatment strategies are still required.

authors

Joyce PR

doi

10.1097/00004850-198804000-00003

subject

Has Abstract

pub_date

1988-04-01 00:00:00

pages

123-9

issue

2

eissn

0268-1315

issn

1473-5857

journal_volume

3

pub_type

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