Abstract:
:A new selective MAO-A-inhibitor (noclobemide) was used in a double-blind comparative study of 23 patients with severe unipolar or bipolar depressive disorder. Two different doses of medication were given for 4 weeks. Effectiveness was measured by improvements in the Hamilton Rating Scale for Depression, a self-rating scale and clinical global impression. Platelet MAO-activity and urinary MHPG-excretion was also determined. Moclobemide proved to be a well-tolerated and effective antidepressant, with both groups showing improvement. Platelet MAO-activity was not markedly influenced by moclobemide, possibly because it selectively inhibits MAO-A. Urinary MHPG did not change significantly with treatment.
journal_name
Int Clin Psychopharmacoljournal_title
International clinical psychopharmacologyauthors
Lensch K,Fuchs G,Böning J,Milech Udoi
10.1097/00004850-198704000-00011subject
Has Abstractpub_date
1987-04-01 00:00:00pages
165-71issue
2eissn
0268-1315issn
1473-5857journal_volume
2pub_type
临床试验,杂志文章abstract::This study aimed to compare the effectiveness of parental training (PT), methylphenidate treatment (MPH), and the combination of PT and MPH treatment (PT/MPH) on school achievements in children with attention-deficit hyperactivity disorder (ADHD). Twenty eight ADHD patients (age: 10.1±1.11 years) were divided into thr...
journal_title:International clinical psychopharmacology
pub_type: 杂志文章,随机对照试验
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更新日期:2018-07-01 00:00:00
abstract::The effect of prophylactic treatment with depot antipsychotic drugs was examined in 16 patients with bipolar affective disorder. The frequency and duration of illness episodes occurring during depot treatment was compared to that which occurred when these patients were treated with other agents over a corresponding ti...
journal_title:International clinical psychopharmacology
pub_type: 杂志文章
doi:10.1097/00004850-199300820-00007
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journal_title:International clinical psychopharmacology
pub_type: 杂志文章
doi:10.1097/00004850-199506000-00004
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journal_title:International clinical psychopharmacology
pub_type: 杂志文章,多中心研究,随机对照试验
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abstract::The tricyclic antidepressants (TCAs) are still considered as first-line treatment for depression, despite the availability of the selective serotonin reuptake inhibitors (SSRIs). This paper considers the current situation in reverse by assuming that only the SSRIs, in particular fluvoxamine, are available and the TCAs...
journal_title:International clinical psychopharmacology
pub_type: 杂志文章,评审
doi:
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journal_title:International clinical psychopharmacology
pub_type: 杂志文章,评审
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journal_title:International clinical psychopharmacology
pub_type: 杂志文章
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journal_title:International clinical psychopharmacology
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:International clinical psychopharmacology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:1996-06-01 00:00:00
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journal_title:International clinical psychopharmacology
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journal_title:International clinical psychopharmacology
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journal_title:International clinical psychopharmacology
pub_type: 杂志文章,评审
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journal_title:International clinical psychopharmacology
pub_type: 杂志文章,随机对照试验
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journal_title:International clinical psychopharmacology
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:International clinical psychopharmacology
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journal_title:International clinical psychopharmacology
pub_type: 杂志文章
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journal_title:International clinical psychopharmacology
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journal_title:International clinical psychopharmacology
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journal_title:International clinical psychopharmacology
pub_type: 杂志文章,评审
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journal_title:International clinical psychopharmacology
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journal_title:International clinical psychopharmacology
pub_type: 临床试验,杂志文章
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journal_title:International clinical psychopharmacology
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journal_title:International clinical psychopharmacology
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journal_title:International clinical psychopharmacology
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