Abstract:
:In theory, lymphokine-activated killer (LAK) cells offer a potential method to treat cerebral gliomas, especially low-grade gliomas. LAK cells would be administered by repeated injections straight into the cavity of a subtotally removed tumour. However, brain-tumour cyst fluid has been shown to be immunosuppressive in lymphocyte stimulation tests. Therefore we wanted to know whether the fluid would reduce the killing efficacy of LAK cells. Using a standard cytotoxity test based on 51Cr release, we compared in vitro the cytotoxity of LAK cells against K-562 tumour cells in brain-tumour cyst fluid, autologous serum and allogeneic serum. Five patients with cystic glioma and one with cystic meningioma were studied and no inhibition of cytotoxity of LAK cells was observed.
journal_name
Acta Neurochir (Wien)journal_title
Acta neurochirurgicaauthors
Jääskeläinen J,Kalliomäki P,Paetau A,Saksela E,Timonen Tdoi
10.1007/BF01400532subject
Has Abstractpub_date
1988-01-01 00:00:00pages
73-8issue
1-2eissn
0001-6268issn
0942-0940journal_volume
91pub_type
杂志文章abstract::We investigated the vasodilatory effect of intracisternal (i.c.) and intravenous (i.v.) administration of calcitonin gene-related peptide (CGRP) on arterial narrowing after experimental subarachnoid hemorrhage (SAH). Forty-one rabbits were divided into five groups: control (normal animals); SAH plus i.c. infusion of v...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01541797
更新日期:1992-01-01 00:00:00
abstract::Three patients with symmetrical bilateral low-density areas which were the perfusion territories of Heubner's arteries are reported. The infarctions were demonstrated on computed tomography after aneurysm surgery. Two of them had an anterior communicating artery aneurysm and the other one had multiple aneurysms of bot...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01418830
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Anterior cranial fossa dural arterio-venous fistulas (DAVFs) represent 6% of all intracranial DAVFs; characteristically they show an aggressive behaviour with high risk of intracranial haemorrhage. Peculiar anatomical features, such as feeding by the ethmoidal arteries and the pattern of venous drainage (fre...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,多中心研究
doi:10.1007/s00701-017-3107-2
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:Neurogenic pulmonary edema (NPE) is a clinical syndrome characterized by the acute onset of pulmonary edema after a significant central nervous system (CNS) insult. NPE occurs as a result of release of catecholamines into the blood immediately after aneurysm rupture. The aim of this study is to investigate t...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-017-3091-6
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to compare the effects of single and dual nerve transfer for the repair of shoulder abduction in patients with upper or upper and middle trunk root avulsion. METHODS:We carried out a retrospective analysis of 20 patients with C5-C6 or C5-C7 root avulsion treated by nerve transfe...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-019-03847-y
更新日期:2019-04-01 00:00:00
abstract::The results of 16 cases of temporal bone resection were evaluated. The resections, 12 of which were total and 4 partial, had mostly been performed for squamous cell carcinoma invading the temporal bone. Five patients in whom the intervention was considered radical and not followed by irradiation, were alive and well 9...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01400676
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVES:Vertebral artery injury (VAI) during foraminal decompression in cervical spine surgery in the absence of repositioning or screw stabilization is rare. Without immediate recognition and treatment, it may have disastrous consequences. We aimed to describe the incidence and management of iatrogenic VAI in low-r...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-015-2594-2
更新日期:2015-11-01 00:00:00
abstract::Somatosensory evoked potentials (SEP) and intracranial pressure (ICP) were studied in cats, suffering from a chronic space-occupying lesion produced by enlargement of an epidural balloon over the left sensomotory cortex. Our study shows that latency alterations of SEP are not dependent on the degree of ICP. Additional...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01446995
更新日期:1993-01-01 00:00:00
abstract::We report three cases of ischaemic complications following direct surgery of unruptured cerebral aneurysms having necks with atherosclerotic or calcified walls. Among 30 patients we treated directly for unruptured aneurysm over the last 4 years, 6 had 8 such aneurysms. Atherosclerotic or calcified neck was a major con...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010050364
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:An understanding of the present standing of surgery, surgical results and the role in altering the future morbidity and mortality of untreated brain arteriovenous malformations (bAVMs) is appropriate considering the myriad alternative management pathways (including radiosurgery, embolization or some combinat...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,评审
doi:10.1007/s00701-017-3217-x
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:A prospective study was undertaken to determine the number of potential organ donors in a neurosurgical intensive care unit and to record the actual number of organ donations. The reasons for refusal of organ donations were analysed with respect to the controversial public discussion of the brain death concep...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010050354
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Brainstem cavernous malformations (CM) carry high risks of hemorrhage and neurologic morbidity. While much is published on physical effects of brainstem CM, very little is known about these patients' quality of life. This study aimed to assess the quality of life PROMIS-29 health domains of brainstem CM pati...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-019-04075-0
更新日期:2019-12-01 00:00:00
abstract::Renal cell carcinoma has a complex and variable natural history. We report a case underlining this who presented concomitant renal cell carcinoma metastasis with pituitary and adrenocortical adenomas. A 62-year-old woman presented with visual loss. Imaging revealed a large sellar mass with suprasellar extension. Four ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-002-1060-0
更新日期:2003-03-01 00:00:00
abstract::An adjustable telescopic suction tube has been developed for microsurgery. Owing to this innovation, the surgeon can easily set the suction tube to a suitable length by gently pulling the end of the telescopic tube out or in. ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01401302
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:Microvascular decompression (MVD) for hemifacial spasm (HFS) has been popular, but it may take enough time to master this special operative technique and procedure. This may induce uneven distribution of the number of MVD operations in each institute, possibly resulting in an overall unsatisfactory quality o...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-013-1724-y
更新日期:2013-09-01 00:00:00
abstract::Cavernous malformations (CMs) of the midbrain and thalamus are relatively rare and particularly difficult to be resected given their location in eloquent tissues. Here, we report a case of a 14-year-old boy who experienced repeated and progressive right hemiparesis. Image examinations showed a gradually enlarged CM or...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-016-2870-9
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:As technical progress advances, telemonitoring has become an important part of patient care in many areas of medical treatment. However, distanced surveillance of intracranial pressure (ICP) could not be established so far. With the recent introduction of a telemetric ICP measurement probe, new possibilities...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-019-03959-5
更新日期:2019-08-01 00:00:00
abstract::Meningiomas are tumors arising from the meninges and represent the most frequent central nervous system tumors in adults. Recent large-scale genetic studies and preclinical meningioma mouse modelling led to a better comprehension of meningioma development and suggested evidences of close relationships between meningea...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,评审
doi:10.1007/s00701-020-04650-w
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Chronic subdural haematomas (cSDHs) have shown an increasing incidence in an ageing population over the last 20 years, while unacceptable recurrence rates of up to 30 % persist. The recurrence rate of cSDH seems to be related to the excessive neoangiogenesis in the parietal membrane, which is mediated via va...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00701-016-2949-3
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVES:The purpose of this report was to review our experience with stereotactic radiosurgery in the management of patients with residual neurocytomas after initial surgery. METHODS:Between October 1996 and December 2001, four patients with central neurocytoma were treated by surgery and subsequently underwent lin...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-003-0076-4
更新日期:2003-09-01 00:00:00
abstract::One case of a pontine haematoma with clinical symptoms of cerebellopontine angle tumour is described. The haematoma was successfully evacuated, and preoperative neurological deficits disappeared except for minimal right fifth nerve palsy. The pathological specimen was diagnosed as arteriovenous malformation. Lateropon...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF02055855
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND:We developed a new simple therapeutic method for the treatment of chronic subdural hematoma (CSDH) without irrigation and drainage. This method is characterized by replacement of the hematoma with oxygen. METHODS:Seventy patients (seventy-eight sides) with CSDH were treated with this method from May 1994 to...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-005-0689-x
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:Trigeminal neuralgia (TN) is primarily diagnosed by symptoms and patient history. Magnetic resonance (MR) imaging can be helpful in visualizing the neurovascular compression of the trigeminal nerve in TN patients, but the current parameters used as diagnostic markers for TN are less than optimal. The aim of ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-012-1327-z
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Entrapped fourth ventricle is the result of both inlet aqueduct and outlet fourth ventricular midline and lateral foraminae obstruction. It occurs as a sequalae of intracranial hemorrhagic or inflammatory disease condition. Usually it presents after previous shunting for communicating hydrocephalus with a pe...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-013-1843-5
更新日期:2013-10-01 00:00:00
abstract::Traditional clinical outcome measures for the treatment of Parkinson's disease (PD) have focused on motor function and activities of daily living. However, in the past decade there has been a new emphasis on the use of health related quality of life (HRQOL) measures for translating how a patient's response to treatmen...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010070090
更新日期:2000-01-01 00:00:00
abstract::The growth of a small arteriovenous angioma over a period of almost 18 years in a 20 year old patient has been proved by arteriography. This case is added to 29 cases previously published in the literature. The authors do not readily accept the theory of autochthonous growth, but prefer secondary or "pseudo-growth". I...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01405394
更新日期:1977-01-01 00:00:00
abstract::In a period of 13 years 978 cases of severe head injuries were operated on in our clinic. An analysis of the medical reports includes injuries of the superficial dural sinus (39 cases = 4%): among these injuries of the anterior and central part of the superior sagittal sinus (66 per cent), injuries of the transverse s...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01541788
更新日期:1992-01-01 00:00:00
abstract::Forty one cases of subdural empyema treated between 1977 and 1988 at the Postgraduate Institute of Medical Education and Research. Chandigarh, have been analysed. The patients ranged from 9 days to 80 years of age. There were 22 children, including 11 infants. Fever, altered sensorium and seizures were the most common...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,评审
doi:10.1007/BF01402182
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:This prospective observational study was undertaken to investigate the advantages, the safety, and the drawbacks of reconstructing a cervical corpectomy with a distractible corpectomy cage. According to the author's literature search, this is the second clinical report on a distractible cervical corpectomy c...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-006-0871-9
更新日期:2006-11-01 00:00:00
abstract::Hormonal disturbances caused by hypothalamic pathology can be treated effectively by target hormone replacement in the case of failure of glandotropic hormone secretion. Hyposomatotropism in children has to be substituted by parenteral administration of growth hormone. In addition gonadotropins respectively gonadotrop...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01406335
更新日期:1985-01-01 00:00:00