Effect of intracisternal and intravenous calcitonin gene-related peptide on experimental cerebral vasospasm in rabbits.

Abstract:

:We investigated the vasodilatory effect of intracisternal (i.c.) and intravenous (i.v.) administration of calcitonin gene-related peptide (CGRP) on arterial narrowing after experimental subarachnoid hemorrhage (SAH). Forty-one rabbits were divided into five groups: control (normal animals); SAH plus i.c. infusion of vehicle; SAH plus i.c. infusion of CGRP; SAH plus i.v. infusion of vehicle; SAH plus i.v. infusion of CGRP. In all but the control group, either CGRP (100 ng/kg/min) or vehicle solution was infused for two hours immediately prior to sacrifice by perfusion-fixation. A morphometric technique was employed to measure the luminal diameter of rabbit basilar arteries two days after SAH. The diameter of the basilar arteries in either the i.c. or i.v. CGRP groups was significantly greater than that of the respective vehicle group (i.c., p < 0.001; i.v., p < 0.01). Although there was no significant difference in systemic arterial blood pressure after infusion between the i.c. vehicle and i.c. CGRP groups, i.v. CGRP caused significant hypotension. Our results suggest that exogenous CGRP has some therapeutic potential for arterial narrowing after SAH not only by intrathecal application, but also by systemic use.

journal_name

Acta Neurochir (Wien)

journal_title

Acta neurochirurgica

authors

Toshima M,Kassell NF,Tanaka Y,Dougherty DA

doi

10.1007/BF01541797

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

134-8

issue

1-4

eissn

0001-6268

issn

0942-0940

journal_volume

119

pub_type

杂志文章
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    doi:10.1007/BF01401682

    authors: Schiffer D,Giordana MT,Soffietti R,Tarenzi L,Milani R,Vasario E,Paoletti P

    更新日期:1981-01-01 00:00:00

  • Relation of cerebral vasospasm to operative findings of subarachnoid blood around ruptured aneurysms.

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    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/BF01401750

    authors: Tomasello F,Albanese V,Picozzi P,Spadaro A,Conforti P

    更新日期:1982-01-01 00:00:00

  • Acute serious rebleeding after angiographically successful coil embolization of ruptured cerebral aneurysms.

    abstract:PURPOSE:The present study investigated the incidence of acute rebleeding after successful coil embolization of a ruptured cerebral aneurysm, including clinical outcomes, and possible mechanisms of the events other than coil compaction and/or incomplete embolization. MATERIALS AND METHODS:This study included 591 consec...

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    pub_type: 杂志文章

    doi:10.1007/s00701-009-0593-x

    authors: Kang DH,Kim YS,Baik SK,Park SH,Park J,Hamm IS

    更新日期:2010-05-01 00:00:00

  • Unexpected death after occipital condylar fracture.

    abstract::We present a rare fatal complication of an occipital condylar fracture. The patient was initially neurologically intact, but showed secondary clinical deterioration. Imaging revealed extensive extra-axial hemorrhage at the craniocervical junction and an acute obstructive hydrocephalus. MR imaging demonstrated a T2 hyp...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-017-3165-5

    authors: Bulthuis VJ,Cornips EMJ,Dings J,van Santbrink H,Postma AA

    更新日期:2017-06-01 00:00:00

  • Primary cervical spinal epidural Extra-osseous Ewing's sarcoma.

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    pub_type: 杂志文章

    doi:10.1007/s00701-004-0294-4

    authors: Kogawa M,Asazuma T,Iso K,Koike Y,Domoto H,Aida S,Fujikawa K

    更新日期:2004-09-01 00:00:00

  • Transsphenoidal approaches to the pituitary: a progression in experience in a single centre.

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    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-008-0135-y

    authors: Duz B,Harman F,Secer HI,Bolu E,Gonul E

    更新日期:2008-11-01 00:00:00

  • Melanotic neuroectodermal tumor of infancy (MNT1) arising in the skull. Short review of two cases.

    abstract:INTRODUCTION:Melanotic neuroectodermal tumor of infancy (MNT1) is a rare congenital pigmented neoplasm of neural crest origin, locally aggressive, and rapidly growing that develops during the first year of life. It most commonly arises from the maxilla, the cranial vault, and the mandible. Early diagnosis and radical s...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章,随机对照试验,评审

    doi:10.1007/s00701-009-0472-5

    authors: Lambropoulos V,Neofytou A,Sfougaris D,Mouravas V,Petropoulos A

    更新日期:2010-05-01 00:00:00

  • Percutaneous balloon compression of the Gasserian ganglion in trigeminal neuralgia. Long-term results in 150 cases.

    abstract::One hundred and fifty patients with trigeminal neuralgia were treated by percutaneous compression of the Gasserian ganglion (PCGG) during the last 8 years. The technique is the one described by Mullan with the balloon inflated during 6 minutes with 0,7 cc of contrast medium. Over a follow-up period ranging from 6 mont...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/BF01411438

    authors: Abdennebi B,Bouatta F,Chitti M,Bougatene B

    更新日期:1995-01-01 00:00:00

  • Double balloon protection during carotid artery stenting for vulnerable carotid stenosis reduces the incidence of new brain lesions.

    abstract:BACKGROUND:The use of distal filter protection alone is associated with a high risk of ischemic complications when vulnerable carotid stenosis is treated by carotid artery stenting (CAS). Double balloon protection, a combination of distal balloon protection and proximal balloon occlusion, can be utilized. We assessed t...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-016-2816-2

    authors: Nakazaki M,Nonaka T,Takahashi A,Yonemasu Y,Nomura T,Onda T,Honda O,Hashimoto Y,Ohnishi H,Sasaki M,Daibo M,Honmou O

    更新日期:2016-07-01 00:00:00

  • Verification of the Schaltenbrand and Wahren stereotactic atlas.

    abstract::The Schaltenbrand and Wahren stereotactic atlas was critically re-examined focusing on the technical quality and the consistency of the horizontal, sagittal and frontal microscopic cut series. From each series, both an isotropic contour and a solid volume model represented by a 256 matrix with an edge length of 6.4 cm...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/BF01400876

    authors: Niemann K,Naujokat C,Pohl G,Wollner C,von Keyserlingk D

    更新日期:1994-01-01 00:00:00

  • [The microsurgical treatment of the so-called tuberculum-sellae-meningiomas (author's transl)].

    abstract::Experience from five cases operated on within one year (among 50 microsurgical operations at the base of the brain) persuades us to discuss the topical relations of the meningiomas of the tuberculum sellae and the modifications in operating techniques necessary. For the two contrasting types of tumour found, which are...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/BF01401930

    authors: Hänsel G,Seeger W

    更新日期:1977-01-01 00:00:00

  • Persistent vegetative state after multiple trauma. A clinicopathologic study.

    abstract::The clinico-pathological findings are reported in a case with persistent vegetative state after multiple cerebral lesions. The lesions are small in size, and are situated at different levels of the CNS, some of them being important in the maintenance of wakefulness and motor initiative. The differential diagnosis and ...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/BF01411190

    authors: Arseni C,Nereanţiu F,Carp N

    更新日期:1981-01-01 00:00:00

  • The value of short-term pain relief in predicting the 1-month outcome of 'indirect' cervical epidural steroid injections.

    abstract:BACKGROUND:Clinical management after epidural steroid injections (ESI) of patients with radiculopathy secondary to a cervical disc herniation (CDH) is uncertain. This study aims to determine whether short-term arm pain alleviation following computed tomography-guided 'indirect' cervical ESI can predict the 1-month outc...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-016-2997-8

    authors: Joswig H,Neff A,Ruppert C,Hildebrandt G,Stienen MN

    更新日期:2017-02-01 00:00:00

  • Cortical blood flow recorded during early or delayed surgery for ruptured intracranial aneurysms.

    abstract::Forty-three patients were operated on for ruptured intracranial aneurysms during a 12-month-period. Intraoperative evaluation of cortical blood flow by means of a thermal diffusion probe was performed in 23 out of the 41 patients who were operated on for aneurysms of the anterior circulation. The autoregulation index ...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/BF01401447

    authors: Viale GL,Cossu M,Cella F,Balestrero M,Rossi A,Masoni D

    更新日期:1994-01-01 00:00:00

  • Optic nerve gliomas. I. Clinical diagnosis and pathology.

    abstract::At the National Institute of Neurosurgery a team of ophthalmologists and neurosurgeons has for 20 years been collaborating in the research and treatment of optic nerve gliomas. Among 34 patients, 30 were under the age of 20 years, and 20 under the age of 10 years. Of the 20 patients younger than 10 years, 16 were girl...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/BF01809149

    authors: Pásztor E,Remenár L

    更新日期:1978-01-01 00:00:00

  • Cerebral mixed tumour: osteo-condrosarcoma--glioblastoma multiforme.

    abstract::A 49-year-old woman had a left frontal expanding mass with calcified areas. A craniotomy and resection of the mass were performed. Histological sections showed a mixed tumour: osteochondrosarcoma-glioblastoma multiforme. The absence of previous irradiation and its location, deep in the frontal lobe and apparently unat...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/BF01808532

    authors: Sarmiento J,Ferrer I,Pons L,Ferrer E

    更新日期:1979-01-01 00:00:00

  • Bilateral internal carotid artery thrombosis after closed head injury.

    abstract::A case of bilateral internal carotid artery thrombosis after blunt injury to the head in a 54 years old male is described. The literature is reviewed and comment is made on the causes. Unilateral thrombosis of the internal carotid artery after closed or blunt injury to the head and neck is well known but not common. T...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/BF01401637

    authors: Robinson RG,Gwynne JF

    更新日期:1978-01-01 00:00:00

  • Histological change in permanently clipped or ligated cerebral arterial wall. Part I. An experimental study in dogs.

    abstract::In this paper, we discuss the results of a study by light microscope of the effect of permanent clipping or ligation on the intracranial arteries of 38 operation dogs and 7 control dogs. The findings obtained are: 1. In the cerebral arterial circle, necrosis could easily result from ordinary clipping or ligation becau...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/BF01405851

    authors: Ebina K,Iwabuchi T,Suzuki S

    更新日期:1982-01-01 00:00:00

  • No apparent role for neutrophils and neutrophil-derived myeloperoxidase in experimental subarachnoid haemorrhage and vasospasm: a preliminary study.

    abstract:OBJECTIVE:The literature contains investigations and discussion of the role of neutrophils and neutrophil-derived myeloperoxidase (MPO) in inflammatory processes, local ischaemia, and ischaemia-reperfusion injury models. Our aim was to determine whether the same roles existed for neutrophils and the system involving ne...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s007010050011

    authors: Oruckaptan HH,Caner HH,Kilinc K,Ozgen T

    更新日期:2000-01-01 00:00:00

  • Comparison between the C5 or C6-Cz electrode assembly and C3 or C4-Cz assembly for transcranial electric motor activation of muscular response of the contralateral facial nerve.

    abstract:OBJECTIVE:We used an assembly of electrodes C3 and C4-Cz in order to activate the motor cortical area of the corticobulbar tract to elucidate the motor-evoked potential of the contralateral mentalis muscle. METHOD:We compared this setup to that of an assembly with electrodes C5 or C6-Cz using a train of electrical pul...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-012-1505-z

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    更新日期:2012-12-01 00:00:00

  • Chronic subdural haematoma in elderly patients: a retrospective analysis of 322 patients between the ages of 65-94 years.

    abstract:BACKGROUND:Chronic subdural haematoma (cSDH) is a common disease in neurosurgical practise, especially in elderly patients. This is of growing importance as the number of elderly people in the population is increasing steadily. There are scarce data focussing especially on elderly patients with cSDH. This study intende...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-012-1434-x

    authors: Borger V,Vatter H,Oszvald Á,Marquardt G,Seifert V,Güresir E

    更新日期:2012-09-01 00:00:00

  • Intraoperative monitoring of sensory part of the trigeminal nerve using blink reflex during microvascular decompression for trigeminal neuralgia.

    abstract::Intraoperative monitoring during cerebellopontine angle surgery is widely accepted. While techniques which monitor cranial motor nerves are commonly used, monitoring the sensory afferents has been challenging. Considering the reflex arc, blink reflex (BR) might be useful in monitoring the sensory part of the trigemina...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-017-3405-8

    authors: Simioni V,Capone JG,Sette E,Granieri E,Farneti M,Cavallo MA,Tugnoli V

    更新日期:2018-01-01 00:00:00

  • Clinical features of postoperative cerebral venous infarction.

    abstract::There is a potential risk of sacrificing the cortical vein during neurosurgical operations, particularly in the interhemispheric or subtemporal approach. An impaired cortical vein might cause cerebral venous circulatory disturbances (CVCDs) resulting in venous infarction. In this article, we have reviewed the manageme...

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-005-0501-y

    authors: Nakase H,Shin Y,Nakagawa I,Kimura R,Sakaki T

    更新日期:2005-06-01 00:00:00

  • Current accuracy of surface matching compared to adhesive markers in patient-to-image registration.

    abstract:OBJECT:In the past, the accuracy of surface matching has been shown to be disappointing. We aimed to determine whether this had improved over the years by assessing application accuracy of current navigation systems, using either surface matching or point-pair matching. METHODS:Eleven patients, scheduled for intracran...

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    pub_type: 杂志文章

    doi:10.1007/s00701-019-03867-8

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  • Childhood and adolescent meningiomas: a report of 38 cases and review of literature.

    abstract:BACKGROUND:The aim is to study the clinical, radiological and pathological features of childhood and adolescent meningiomas and analyse outcome prognosticators. METHOD:A retrospective analysis of the case records of patients less than 20 years of age operated for a meningioma in our institute since 1982 was performed....

    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-009-0206-8

    authors: Menon G,Nair S,Sudhir J,Rao BR,Mathew A,Bahuleyan B

    更新日期:2009-03-01 00:00:00

  • Deep brain stimulation of the subthalamic nucleus versus the zona incerta in the treatment of essential tremor.

    abstract:BACKGROUND:Deep brain stimulation (DBS) is an effective treatment for essential tremor (ET). Currently the ventrolateral thalamus is the target of choice, but the posterior subthalamic area (PSA), including the caudal zona incerta (cZi), has demonstrated promising results, and the subthalamic nucleus (STN) has been sug...

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    pub_type: 临床试验,杂志文章

    doi:10.1007/s00701-011-1157-4

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    更新日期:2011-12-01 00:00:00

  • Giant cell tumor of the lumbar spine with intraperitoneal growth: case report and review of literature.

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    pub_type: 杂志文章,评审

    doi:10.1007/s00701-013-1713-1

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    更新日期:2013-07-01 00:00:00

  • Demonstration of the optic pathway in sellar/juxtasellar tumours with visual disturbance on MR imaging.

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    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s007010050138

    authors: Sumida M,Arita K,Migita K,Iida K,Kurisu K,Uozumi T

    更新日期:1998-01-01 00:00:00

  • Multilocular lesions in the therapy of cerebral palsy.

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    pub_type: 杂志文章

    doi:10.1007/978-3-7091-8482-0_2

    authors: Mundinger F,Ostertag C

    更新日期:1977-01-01 00:00:00

  • Gliadel wafer in initial surgery for malignant glioma: long-term follow-up of a multicenter controlled trial.

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    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1007/s00701-005-0707-z

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    更新日期:2006-03-01 00:00:00