Abstract:
:We investigated the vasodilatory effect of intracisternal (i.c.) and intravenous (i.v.) administration of calcitonin gene-related peptide (CGRP) on arterial narrowing after experimental subarachnoid hemorrhage (SAH). Forty-one rabbits were divided into five groups: control (normal animals); SAH plus i.c. infusion of vehicle; SAH plus i.c. infusion of CGRP; SAH plus i.v. infusion of vehicle; SAH plus i.v. infusion of CGRP. In all but the control group, either CGRP (100 ng/kg/min) or vehicle solution was infused for two hours immediately prior to sacrifice by perfusion-fixation. A morphometric technique was employed to measure the luminal diameter of rabbit basilar arteries two days after SAH. The diameter of the basilar arteries in either the i.c. or i.v. CGRP groups was significantly greater than that of the respective vehicle group (i.c., p < 0.001; i.v., p < 0.01). Although there was no significant difference in systemic arterial blood pressure after infusion between the i.c. vehicle and i.c. CGRP groups, i.v. CGRP caused significant hypotension. Our results suggest that exogenous CGRP has some therapeutic potential for arterial narrowing after SAH not only by intrathecal application, but also by systemic use.
journal_name
Acta Neurochir (Wien)journal_title
Acta neurochirurgicaauthors
Toshima M,Kassell NF,Tanaka Y,Dougherty DAdoi
10.1007/BF01541797subject
Has Abstractpub_date
1992-01-01 00:00:00pages
134-8issue
1-4eissn
0001-6268issn
0942-0940journal_volume
119pub_type
杂志文章abstract::The pathological effects of radio- and chemotherapy on the normal nervous tissue have been studied in 42 brains with malignant gliomas. The brains have been examined by means of the complete study technique. In seven cases the picture of delayed radionecrosis has been found. Apart from this, many histological features...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01401682
更新日期:1981-01-01 00:00:00
abstract::An investigation was carried out in 28 patients in order to evaluate the relationship between angiographically documented vasospasm, amount of subarachnoid blood found at surgery around ruptured intracranial aneurysms, and delayed ischaemic deficits. Angiography was performed at time intervals ranging between 5 and 17...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01401750
更新日期:1982-01-01 00:00:00
abstract:PURPOSE:The present study investigated the incidence of acute rebleeding after successful coil embolization of a ruptured cerebral aneurysm, including clinical outcomes, and possible mechanisms of the events other than coil compaction and/or incomplete embolization. MATERIALS AND METHODS:This study included 591 consec...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-009-0593-x
更新日期:2010-05-01 00:00:00
abstract::We present a rare fatal complication of an occipital condylar fracture. The patient was initially neurologically intact, but showed secondary clinical deterioration. Imaging revealed extensive extra-axial hemorrhage at the craniocervical junction and an acute obstructive hydrocephalus. MR imaging demonstrated a T2 hyp...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-017-3165-5
更新日期:2017-06-01 00:00:00
abstract::Cases of primary spinal epidural Extra-osseous Ewing's sarcoma (EES) are rarely seen and a good prognosis for EES cannot be expected since a high incidence of local recurrence and metastasis frequently occur. We present a case of cervical spinal epidural EES in a 7-year-old girl with long survival after tumour resecti...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-004-0294-4
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND:Evolving of a single centre by means of different transsphenoidal approaches during the survey of methodological advances in pituitary surgery is presented. MATERIALS AND METHODS:Ninety-three consecutive patients with pituitary adenomas underwent transphenoidal pituitary operations at Gulhane Military Medic...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-008-0135-y
更新日期:2008-11-01 00:00:00
abstract:INTRODUCTION:Melanotic neuroectodermal tumor of infancy (MNT1) is a rare congenital pigmented neoplasm of neural crest origin, locally aggressive, and rapidly growing that develops during the first year of life. It most commonly arises from the maxilla, the cranial vault, and the mandible. Early diagnosis and radical s...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,随机对照试验,评审
doi:10.1007/s00701-009-0472-5
更新日期:2010-05-01 00:00:00
abstract::One hundred and fifty patients with trigeminal neuralgia were treated by percutaneous compression of the Gasserian ganglion (PCGG) during the last 8 years. The technique is the one described by Mullan with the balloon inflated during 6 minutes with 0,7 cc of contrast medium. Over a follow-up period ranging from 6 mont...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01411438
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:The use of distal filter protection alone is associated with a high risk of ischemic complications when vulnerable carotid stenosis is treated by carotid artery stenting (CAS). Double balloon protection, a combination of distal balloon protection and proximal balloon occlusion, can be utilized. We assessed t...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-016-2816-2
更新日期:2016-07-01 00:00:00
abstract::The Schaltenbrand and Wahren stereotactic atlas was critically re-examined focusing on the technical quality and the consistency of the horizontal, sagittal and frontal microscopic cut series. From each series, both an isotropic contour and a solid volume model represented by a 256 matrix with an edge length of 6.4 cm...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01400876
更新日期:1994-01-01 00:00:00
abstract::Experience from five cases operated on within one year (among 50 microsurgical operations at the base of the brain) persuades us to discuss the topical relations of the meningiomas of the tuberculum sellae and the modifications in operating techniques necessary. For the two contrasting types of tumour found, which are...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01401930
更新日期:1977-01-01 00:00:00
abstract::The clinico-pathological findings are reported in a case with persistent vegetative state after multiple cerebral lesions. The lesions are small in size, and are situated at different levels of the CNS, some of them being important in the maintenance of wakefulness and motor initiative. The differential diagnosis and ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01411190
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND:Clinical management after epidural steroid injections (ESI) of patients with radiculopathy secondary to a cervical disc herniation (CDH) is uncertain. This study aims to determine whether short-term arm pain alleviation following computed tomography-guided 'indirect' cervical ESI can predict the 1-month outc...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-016-2997-8
更新日期:2017-02-01 00:00:00
abstract::Forty-three patients were operated on for ruptured intracranial aneurysms during a 12-month-period. Intraoperative evaluation of cortical blood flow by means of a thermal diffusion probe was performed in 23 out of the 41 patients who were operated on for aneurysms of the anterior circulation. The autoregulation index ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01401447
更新日期:1994-01-01 00:00:00
abstract::At the National Institute of Neurosurgery a team of ophthalmologists and neurosurgeons has for 20 years been collaborating in the research and treatment of optic nerve gliomas. Among 34 patients, 30 were under the age of 20 years, and 20 under the age of 10 years. Of the 20 patients younger than 10 years, 16 were girl...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01809149
更新日期:1978-01-01 00:00:00
abstract::A 49-year-old woman had a left frontal expanding mass with calcified areas. A craniotomy and resection of the mass were performed. Histological sections showed a mixed tumour: osteochondrosarcoma-glioblastoma multiforme. The absence of previous irradiation and its location, deep in the frontal lobe and apparently unat...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01808532
更新日期:1979-01-01 00:00:00
abstract::A case of bilateral internal carotid artery thrombosis after blunt injury to the head in a 54 years old male is described. The literature is reviewed and comment is made on the causes. Unilateral thrombosis of the internal carotid artery after closed or blunt injury to the head and neck is well known but not common. T...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01401637
更新日期:1978-01-01 00:00:00
abstract::In this paper, we discuss the results of a study by light microscope of the effect of permanent clipping or ligation on the intracranial arteries of 38 operation dogs and 7 control dogs. The findings obtained are: 1. In the cerebral arterial circle, necrosis could easily result from ordinary clipping or ligation becau...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01405851
更新日期:1982-01-01 00:00:00
abstract:OBJECTIVE:The literature contains investigations and discussion of the role of neutrophils and neutrophil-derived myeloperoxidase (MPO) in inflammatory processes, local ischaemia, and ischaemia-reperfusion injury models. Our aim was to determine whether the same roles existed for neutrophils and the system involving ne...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010050011
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:We used an assembly of electrodes C3 and C4-Cz in order to activate the motor cortical area of the corticobulbar tract to elucidate the motor-evoked potential of the contralateral mentalis muscle. METHOD:We compared this setup to that of an assembly with electrodes C5 or C6-Cz using a train of electrical pul...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-012-1505-z
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Chronic subdural haematoma (cSDH) is a common disease in neurosurgical practise, especially in elderly patients. This is of growing importance as the number of elderly people in the population is increasing steadily. There are scarce data focussing especially on elderly patients with cSDH. This study intende...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-012-1434-x
更新日期:2012-09-01 00:00:00
abstract::Intraoperative monitoring during cerebellopontine angle surgery is widely accepted. While techniques which monitor cranial motor nerves are commonly used, monitoring the sensory afferents has been challenging. Considering the reflex arc, blink reflex (BR) might be useful in monitoring the sensory part of the trigemina...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-017-3405-8
更新日期:2018-01-01 00:00:00
abstract::There is a potential risk of sacrificing the cortical vein during neurosurgical operations, particularly in the interhemispheric or subtemporal approach. An impaired cortical vein might cause cerebral venous circulatory disturbances (CVCDs) resulting in venous infarction. In this article, we have reviewed the manageme...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-005-0501-y
更新日期:2005-06-01 00:00:00
abstract:OBJECT:In the past, the accuracy of surface matching has been shown to be disappointing. We aimed to determine whether this had improved over the years by assessing application accuracy of current navigation systems, using either surface matching or point-pair matching. METHODS:Eleven patients, scheduled for intracran...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-019-03867-8
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:The aim is to study the clinical, radiological and pathological features of childhood and adolescent meningiomas and analyse outcome prognosticators. METHOD:A retrospective analysis of the case records of patients less than 20 years of age operated for a meningioma in our institute since 1982 was performed....
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-009-0206-8
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:Deep brain stimulation (DBS) is an effective treatment for essential tremor (ET). Currently the ventrolateral thalamus is the target of choice, but the posterior subthalamic area (PSA), including the caudal zona incerta (cZi), has demonstrated promising results, and the subthalamic nucleus (STN) has been sug...
journal_title:Acta neurochirurgica
pub_type: 临床试验,杂志文章
doi:10.1007/s00701-011-1157-4
更新日期:2011-12-01 00:00:00
abstract::Giant cell tumors of the spine are uncommon. Usually they are benign and solitary, but locally very aggressive. Most of them occur at the sacral spine. There are only 26 reported cases in the literature involving this type of tumor in the lumbar spine, in particular exhibiting an intraperitoneal growth. We present the...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,评审
doi:10.1007/s00701-013-1713-1
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVE:To prospectively compare the demonstration of the intracranial optic pathway in patients with sellar/juxtasellar tumours and with clinical evidence of visual disturbance using either spoiled gradient recalled acquisition in steady state (SPGR) or conventional spin echo (CSE) T1-weighted imaging. MATERIALS AN...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010050138
更新日期:1998-01-01 00:00:00
abstract::The cerebral pareses occurring in early childhood or produced subsequently by trauma or spontaneous cerebral haemorrhages, present a heterogenous symptomatic picture. In the forefront we find the spastic pareses associated with extra-pyramidal motor hyperkinesia (athetosis, dystonia, ballism). 36 C.P.-patients were su...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/978-3-7091-8482-0_2
更新日期:1977-01-01 00:00:00
abstract:OBJECTIVE:Adjuvant systemic chemotherapy increases survival of primary malignant glioma patients beyond 12-18 months. The only interstitial chemotherapy treatment approved for malignant glioma is Gliadel wafer containing carmustine (BCNU) placed in the resection cavity at surgery. Analysis of a large trial by Westphal ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s00701-005-0707-z
更新日期:2006-03-01 00:00:00