Abstract:
:This paper presents a general approach for simultaneously assessing, from serial data, diagnostic consistency, interrater reliability and incidence of a strictly progressive disease. Observed data are viewed as incomplete: diagnostic errors are not distinguished from true diagnoses. We introduce a broad class of models to separate rater errors from underlying patterns of disease incidence. The analysis can include covariates and risk factors. We provide variance expressions for parameter estimates. Categorical data for estimating the incidence of dental caries serve as an example.
journal_name
Stat Medjournal_title
Statistics in medicineauthors
Espeland MA,Murphy WC,Leverett DHdoi
10.1002/sim.4780070306subject
Has Abstractpub_date
1988-03-01 00:00:00pages
403-16issue
3eissn
0277-6715issn
1097-0258journal_volume
7pub_type
杂志文章abstract::We consider evaluation and comparison of the diagnostic accuracy of biomarkers with continuous test outcomes, possibly correlated due to repeated measurements. We develop nonparametric group sequential testing procedures to evaluate and compare the area of biomarkers under their receiver operating characteristic curve...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.3203
更新日期:2008-05-10 00:00:00
abstract:BACKGROUND:It has been recommended that onset of antidepressant action be assessed using survival analyses with assessments taken at least twice per week. However, such an assessment schedule is problematic to implement. The present study assessed the feasibility of comparing onset of action between treatments using a ...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.2309
更新日期:2006-07-30 00:00:00
abstract::We suggest measures to quantify the degrees of necessity and of sufficiency of prognostic factors for dichotomous and for survival outcomes. A cause, represented by certain values of prognostic factors, is considered necessary for an event if, without the cause, the event cannot develop. It is considered sufficient fo...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.8331
更新日期:2019-10-15 00:00:00
abstract::In this paper, we proposed a mechanistic breast cancer survival model based on the axillary lymph node chain structure, considering lymph nodes as a potential dissemination arrangement. We assume a naive breast cancer treatment protocol consisting of exposing patients first to a chemotherapy treatment on r intervals a...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.5576
更新日期:2013-04-30 00:00:00
abstract::In England and Wales, a large-scale multiple statistical surveillance system for infectious disease outbreaks has been in operation for nearly two decades. This system uses a robust quasi-Poisson regression algorithm to identify abberrances in weekly counts of isolates reported to the Health Protection Agency. In this...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.5595
更新日期:2013-03-30 00:00:00
abstract::We present a method to estimate the time-dependent vaccine efficacy from the cohort-specific vaccination coverage and from data on the vaccination status of cases and apply it to a measles epidemic in Germany which involved 529 cases, 88 of whom were vaccinated and 370 unvaccinated (for the remaining 71 cases the vacc...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.1043
更新日期:2002-08-30 00:00:00
abstract::In medical research, a two-phase study is often used for the estimation of the area under the receiver operating characteristic curve (AUC) of a diagnostic test. However, such a design introduces verification bias. One of the methods to correct verification bias is inverse probability weighting (IPW). Since the probab...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.8700
更新日期:2020-11-30 00:00:00
abstract::In the analysis of survival data, there are often competing events that preclude an event of interest from occurring. Regression analysis with competing risks is typically undertaken using a cause-specific proportional hazards model. However, modern alternative methods exist for the analysis of the subdistribution haz...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.4123
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journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.4151
更新日期:2011-04-30 00:00:00
abstract::Evaluating treatment effects within different subsets of patients is a common practice in the analysis of individual randomized clinical trials. Such analyses are limited, however, by the number of patients available. Overviews, by providing evidence based on large numbers of patients, can be useful for overcoming the...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.4780060331
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journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.4306
更新日期:2011-11-10 00:00:00
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journal_title:Statistics in medicine
pub_type: 杂志文章,评审
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更新日期:1991-11-01 00:00:00
abstract::To construct a confidence interval for the mean of a log-normal distribution in small samples, we propose likelihood-based approaches - the signed log-likelihood ratio and modified signed log-likelihood ratio methods. Extensive Monte Carlo simulation results show the advantages of the modified signed log-likelihood ra...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.1381
更新日期:2003-06-15 00:00:00
abstract::Important differences between explanatory and pragmatic studies were originally argued by Schwartz and Lellouch. Three important differences between the two types of study involve study control, study violators and inclusion criteria. It was originally argued that explanatory studies are highly controlled, and pragmat...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.1120
更新日期:2002-05-30 00:00:00
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journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.1259
更新日期:2002-11-15 00:00:00
abstract::Biomarkers that predict the efficacy of treatment can potentially improve clinical outcomes and decrease medical costs by allowing treatment to be provided only to those most likely to benefit. We consider the design of a randomized clinical trial in which one objective is to evaluate a treatment selection marker. The...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.6564
更新日期:2015-11-30 00:00:00
abstract::Motivated by a study about prompt coronary angiography in myocardial infarction, we propose a method to estimate the causal effect of a treatment in two-arm experimental studies with possible noncompliance in both treatment and control arms. We base the method on a causal model for repeated binary outcomes (before and...
journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.5856
更新日期:2013-11-10 00:00:00
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journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.5905
更新日期:2013-12-20 00:00:00
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journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/(sici)1097-0258(19981030)17:20<2313::aid-s
更新日期:1998-10-30 00:00:00
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journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.4780060708
更新日期:1987-10-01 00:00:00
abstract::Hierarchical regression analysis holds much promise for epidemiologic analysis, but has as yet seen limited application because of lack of easily used software and the relatively lengthy run times of preferred fitting methods (such as true maximum likelihood and Bayesian approaches). This paper compares three relative...
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pub_type: 杂志文章
doi:10.1002/(sici)1097-0258(19970315)16:5<515::aid-sim
更新日期:1997-03-15 00:00:00
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journal_title:Statistics in medicine
pub_type: 杂志文章
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更新日期:2004-05-30 00:00:00
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journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.4780131905
更新日期:1994-10-15 00:00:00
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pub_type: 杂志文章
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journal_title:Statistics in medicine
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1996-10-15 00:00:00
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journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.6526
更新日期:2015-09-20 00:00:00
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journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.3202
更新日期:2008-09-20 00:00:00
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journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.1482
更新日期:2003-09-15 00:00:00
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journal_title:Statistics in medicine
pub_type: 杂志文章
doi:10.1002/sim.1997
更新日期:2005-01-15 00:00:00
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journal_title:Statistics in medicine
pub_type: 杂志文章
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