Abstract:
:A double-blind evaluation of the antidepressant efficacy of treatment with a combination of orally administered L-tryptophan (L-TP) and electroconvulsive therapy (ECT) was made in patients suffering from endogenous depression. The patients were randomly assigned to two groups, one treated with L-TP (6 g daily) and unilateral ECT, the other with placebo and unilateral ECT. L-TP treatment was initiated at least 1 day before the first ECT and terminated 4 days after the last ECT. There was a good agreement between the two groups in several measures of antidepressant efficacy: doctors' and patients' ratings of depressive symptoms, and doctors' global rating of therapeutic effect 4 days and 1 month after the last ECT. In the L-TP group, however, there was a significantly better effect on retardation symptoms in the nurses' rating scale. This difference, which is not consistent with other measures of amelioration, contributes, at most, to a marginal therapeutic addition to the antidepressant effect of ECT. It is concluded that oral administration of L-TP, in the dose of 6 g daily, is not of practical value for potentiating the antidepressant efficacy of ECT.
journal_name
Acta Psychiatr Scandjournal_title
Acta psychiatrica Scandinavicaauthors
D'Elia G,Lehmann J,Raotma Hdoi
10.1111/j.1600-0447.1977.tb00231.xsubject
Has Abstractpub_date
1977-10-01 00:00:00pages
303-18issue
4eissn
0001-690Xissn
1600-0447journal_volume
56pub_type
临床试验,杂志文章,随机对照试验abstract::The relationship between the family variables of expressed emotion (EE) and communication deviance (CD) and patient attributes of cognitive functions and clinical symptoms were examined. Eleven schizophrenic patients and their parents were evaluated at the beginning and the end of a 2-year treatment programme. The tes...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-0447.1994.tb01569.x
更新日期:1994-08-01 00:00:00
abstract::The aim of this study was to determine whether attributional style is a stable pattern in somatizers, to analyse the sociodemographic and psychopathological characteristics that can modify it, and to study the relationship between attributional pattern and outcome. A total of 147 somatizers and 46 psychologizers from ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1997.tb09658.x
更新日期:1997-05-01 00:00:00
abstract::Quality of life (QOL) was assessed in three groups of patients, consisting of 30 schizophrenic patients with duration of illness <2 years, 30 schizophrenic patients with duration of illness > or = 2 years and 30 dysthymic patients. The diagnoses were made according to ICD-10. Two scales of quality of life were used, o...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1998.tb10002.x
更新日期:1998-04-01 00:00:00
abstract:OBJECTIVE:'Crisis cards' state patients' treatment details and preferences in anticipation of a later occasion when the patient might be too ill to express them directly. We assessed the feasibility of introducing 'crisis cards', or a collaborative form of them, 'joint crisis plans', into a sectorized community psychia...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1999.tb10914.x
更新日期:1999-07-01 00:00:00
abstract:BACKGROUND:Early diagnosis is important for the course of schizophrenia. AIM:To investigate whether prodromal symptoms of schizophrenia lead to increased use of primary care. METHOD:A register-based cohort study of 21 894 cases with incident schizophrenia and 437 880 matched controls. RESULTS:Cases used daytime prim...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12600
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:To evaluate cognitive behaviour therapy for psychosis (CBTp) delivered by non-expert therapists, using CBT relevant measures. METHOD:Participants (N = 74) were randomised into immediate therapy or waiting list control groups. The therapy group was offered 6 months of therapy and followed up 3 months later. T...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-0447.2010.01572.x
更新日期:2010-10-01 00:00:00
abstract::Tardive dyskinesia (TD) is a syndrome of involuntary movements that develops in predisposed individuals during neuroleptic drug treatment, with an average prevalence of 15%. Neuroleptic (antidopaminergic) drugs are the predominant etiological factor. Although no simple correlation can be established, both dosage and t...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0447.1988.tb05138.x
更新日期:1988-04-01 00:00:00
abstract::In a long-term follow-up study of 44 female alcoholics, a family history of alcoholism was related to younger age of onset of problem drinking, but did not necessarily imply a poorer outcome within this highly selected group of individuals. Alcoholism in father and his family was not related to either antisocial or bo...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1987.tb02857.x
更新日期:1987-07-01 00:00:00
abstract::Medico-legal investigation into causes of unexpected death of five persons who suffered from eating disorders did not give distinct pathoanatomical explanations. The analysis disclosed a number of risk factors whose interplay may have resulted in a circulatory catastrophy. These factors were of organisational and ideo...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1986.tb06288.x
更新日期:1986-12-01 00:00:00
abstract::A Swedish version of the Camberwell Family Interview (CFI), a psychiatric, semistructured interview schedule for assessing a family's emotional atmosphere, is described. Thirty-two relatives of patients with schizophrenic disorders, according to DSM-III criteria, were interviewed. Eighteen relatives were interviewed t...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1991.tb03179.x
更新日期:1991-11-01 00:00:00
abstract::This paper reports on the development and testing of a new Chinese diagnostic instrument--the Adult Diagnostic Interview Schedule-Present (ADIS-P). This instrument uses a selection of items adapted from DIS and SADS. It is administered within approximately 25 min by a trained clinician using a small portable computer ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1988.tb05073.x
更新日期:1988-01-01 00:00:00
abstract::Therapeutic relationship has been considered an important ingredient of all psychotherapies. In communities in which no familiar conventions of such a relationship are available, the therapeutic encounter poses very different problems from those in the West, where such conventions freely prevail. This study has been c...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1985.tb02547.x
更新日期:1985-06-01 00:00:00
abstract::Ten patients with manic psychosis were compared with 20 normal subjects with respect to their ratings of emotional meaning in music. As stimulus two pieces of music for a small symphony orchestra were used. These were structurally identical but performed at two different tempos: slow and fast. The change in tempo was ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1982.tb00825.x
更新日期:1982-02-01 00:00:00
abstract::The purpose of the present study is to determine the frequency of polypharmacy among psychiatric patients in Helsinki, and to ascertain whether this practice is supported by clinical trials. The drugs prescribed in 1 day to a sample of patients (n = 694) in mental hospitals and outpatient clinics in Helsinki were stud...
journal_title:Acta psychiatrica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.1111/j.1600-0447.1977.tb06676.x
更新日期:1977-11-01 00:00:00
abstract::The symptom of anhedonia, or loss of pleasure, is widely recognized to occur in depression. More recently it has been suggested that this symptom alone might be the basis for a diagnosis of depression in medically ill patients, and the Hospital Anxiety and Depression Scale (HAD) has been designed with this in mind. To...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1991.tb05534.x
更新日期:1991-04-01 00:00:00
abstract::302 mentally retarded adults, sampled by epidemiological criteria, were examined with regard to epilepsy and psychiatric disorder. Each of the complications was frequent and related to degree and origin of mental retardation. In 55 (18.2%) epilepsy had occurred at some time during their lives, in 25 (8.3%) of these in...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1985.tb02654.x
更新日期:1985-12-01 00:00:00
abstract::In this study a newly developed Self-rating Inventory for Posttraumatic Stress Disorder (PTSD) is presented. The instrument consists of 47 items, reflecting DSM-III-R criteria, associated features and items corresponding to the disorder of extreme stress not otherwise specified. All items are phrased in a trauma-indep...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1994.tb01574.x
更新日期:1994-09-01 00:00:00
abstract:OBJECTIVE:To investigate psychiatric outcomes after bariatric surgery, including suicide, self-harm, psychiatric service use and substance misuse. METHOD:Retrospective study on a Danish nationwide register-based cohort of 22 451 patients followed for 1 029 736 person-years. Data were analysed utilizing single- and mul...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.12669
更新日期:2017-02-01 00:00:00
abstract:OBJECTIVE:Non-suicidal self-injury (NSSI) comprising thoughts and behaviors is common and often co-occurring with suicidal behavior like ideation, plan, and attempt. As limited data are available for adolescents and young adults, this study aims to present prevalence estimates for lifetime NSSI, its co-occurrence with ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/acps.13237
更新日期:2020-12-01 00:00:00
abstract::On the hypothesis that drug addiction may be due to "masked depression", lithium was administered to 20 opiate addicts. Only nine patients took the lithium carbonate tablets for more than a few weeks; during this period they seemed to abstain from taking opiates. After 1 year, all the patients were off lithium and mos...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1975.tb00047.x
更新日期:1975-11-01 00:00:00
abstract::This study set out to describe the sexual attitudes and behaviour of 50 hospitalized alcoholic men by comparing them with a sample of the general population, matched in age and social class. This control sample was identified by random selection from a company register, and subjects were recruited into the study with ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1978.tb00236.x
更新日期:1978-10-01 00:00:00
abstract::In a study of psychotherapy in schizophrenic patients, the existence of certain clinical and anamnestic variables, such as persistent auditory hallucinations, was found to correlate with a negative outcome. To test whether these clinical variables could be a sign of organic brain abnormality, the records of 33 schizop...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1992.tb03299.x
更新日期:1992-12-01 00:00:00
abstract::The validity of a questionnaire developed to assess negative attitudes towards drug therapy by relatives of schizophrenic patients is examined. The questionnaire items are tested against the statement: "Patients should not take drugs, they can only be helped by good advice". The prejudice of relatives of schizophrenic...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1985.tb01269.x
更新日期:1985-02-01 00:00:00
abstract::The leisure activities of 110 depressed patients and of 98 non-psychiatric controls were studied. The following aspects of leisure behaviour were taken into account: quantity, type (active, passive), frequency, presence of other people, place and satisfaction. In addition, possible relationships between personality an...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1984.tb04515.x
更新日期:1984-01-01 00:00:00
abstract::A retrospective study of factors predicting readmissions and follow-up treatment was undertaken of all first-ever episodes of inpatient care (age under 65), excluding psychotic and organic mental disorders, during 1987 and 1988 in University Psychiatric Clinic in Turku City Hospital, Finland. The cohort consisted of 6...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1995.tb09557.x
更新日期:1995-08-01 00:00:00
abstract::Twenty patients with delirium tremens and related states were investigated from the time of admission until the acute state was over. Using strict diagnostic criteria the material was divided into two groups according to the severity of the clinical condition; nine patients had fully developed delirium tremens (grade ...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1979.tb00550.x
更新日期:1979-11-01 00:00:00
abstract::Few empirical studies have examined the attitudes and ethical beliefs of psychiatrists. In this study, 328 members of the Swedish Psychiatric Association were randomly selected to respond to a questionnaire containing three clinical vignettes examining involuntary hospitalization, other compulsory interventions, and r...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1996.tb10665.x
更新日期:1996-05-01 00:00:00
abstract::During the Second World War 70,000-75,000 Finnish children were sent to Sweden to protect them from the war. This article describes a group of children sent to Sweden from Kuopio County. The management of this group is discussed in light of their health, education and profession in adulthood. The change in culture and...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1989.tb01338.x
更新日期:1989-09-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to further evaluate the oestrogen hypothesis of schizophrenia, which postulates low oestradiol levels to be a risk factor for these disorders. A possible influence of neuroleptic-induced hyperprolactinaemia was to be addressed. METHOD:Sex hormones were measured and cycle phase asses...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1046/j.1600-0447.2003.00251.x
更新日期:2004-04-01 00:00:00
abstract::Koro is an acute anxiety reaction in which the perception of decreased penis length because of intra-abdominal traction is the main feature. This study attempts to explore the penis-root perception of the Koro patients by a graphomotor projective test--the Draw-a-penis Test (DAPT). This controlled DAPT investigation s...
journal_title:Acta psychiatrica Scandinavica
pub_type: 杂志文章
doi:10.1111/j.1600-0447.1991.tb01413.x
更新日期:1991-07-01 00:00:00