Diagnosis and management of nasal congestion: the role of intranasal corticosteroids.

Abstract:

:Nasal congestion is considered the most bothersome of allergic rhinitis (AR) symptoms and can significantly impair ability to function at work, home, and school. Effective management of AR-related nasal congestion depends on accurate diagnosis and appropriate treatment. Many individuals with AR and AR-related congestion remain undiagnosed and do not receive prescription medication. However, new tools intended to improve the diagnosis of nasal congestion have been developed and validated. Intranasal corticosteroids (INSs) are recommended as first-line therapy for patients with moderate-to-severe AR and also when nasal congestion is a prominent symptom. Double blind, randomized clinical trials have demonstrated greater efficacy of INSs versus placebo, antihistamines, or montelukast for relief of all nasal symptoms, especially congestion. Patient adherence to treatment also affects outcomes, and this may be influenced by patient preferences for the sensory attributes of an individual drug. Increased awareness of the effects of AR-related nasal congestion, the efficacy and safety of available pharmacotherapies, and barriers to adherence may improve clinical outcomes.

journal_name

Postgrad Med

journal_title

Postgraduate medicine

authors

Benninger M

doi

10.3810/pgm.2009.01.1961

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

122-31

issue

1

eissn

0032-5481

issn

1941-9260

journal_volume

121

pub_type

杂志文章,评审
  • Intervention in family violence. A role for the physician-and for society.

    abstract::Contrary to long-standing mores, what goes on in the person's home is not always sacred. When family relationships break down and family members deal violently with various stresses and problems, intervention is in order. Certain changes in societal attitudes would help prevent the problem. Physicians-alone or working...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1982.11716255

    authors: Pelton CL

    更新日期:1982-11-01 00:00:00

  • What private-practice doctors can do to contain costs. Steps you can take to preserve a free market.

    abstract::Not all of the costs of private practice, particularly those related to government regulation, are within your control. However, there are steps, both large and small, that you can take to get fees under control and to eliminate or reduce expenditures. Dr Orient suggests a number of these. ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:

    authors: Orient JM

    更新日期:1994-02-15 00:00:00

  • How to manage other risk factors in patients with hypertension.

    abstract::High blood pressure is unquestionably a risk factor for premature morbidity and mortality, especially from coronary artery disease and stroke. Risk of clinical manifestations of coronary artery disease increases dramatically if other risk factors, such as a history of cigarette smoking, hypercholesterolemia, left vent...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1989.11704482

    authors: Borhani NO

    更新日期:1989-11-01 00:00:00

  • Carcinoma of the lung. Who will benefit from surgery?

    abstract::The present staging methods for non-small-cell lung cancer provide little more than epidemiologic assessment of prognosis for grossly defined groups of patients. Except in extreme instances, physicians can tell patients very little about their prognosis or the need for supplemental therapy. More effective and less tox...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1990.11704526

    authors: Landreneau RJ

    更新日期:1990-01-01 00:00:00

  • The Medical Bookshelf.

    abstract::Books received are listed as space permits, and those of particular interest to our readers are reviewed. ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1985.11699151

    authors: Scott D

    更新日期:1985-10-01 00:00:00

  • Counseling the parents of birth-defective children.

    abstract::Parents of a child who is diagnosed as defective face a crisis for which they are usually unprepared. They need an opportunity to work through their intense feelings. In addition, they need specific information about how to be of use to their child. Self-help groups composed of parents of children with a similar handi...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1979.11715093

    authors: Vernon M

    更新日期:1979-03-01 00:00:00

  • Maximizing the exercise stress test. Critical factors that enhances its validity.

    abstract::The maximal exercise stress test continues to be an important diagnostic and prognostic tool in the primary care office setting. But are you getting the most accurate information possible? Drs Driggers and Marchant discuss several factors that are crucial to the test's validity--and thus to its usefulness in your clin...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.1999.05.1.737

    authors: Driggers DA,Marchant D

    更新日期:1999-05-01 00:00:00

  • HPV and cervical cancer: updates on an established relationship.

    abstract::Despite cervical cancer being considered a preventable disease, it still remains the second most common malignancy in women worldwide, with a higher incidence in underdeveloped countries. Human papillomavirus (HPV) is considered the causative agent of cervical cancer. The major mechanisms through which HPV contributes...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2008.11.1928

    authors: Subramanya D,Grivas PD

    更新日期:2008-11-01 00:00:00

  • The solitary pulmonary nodule. Is it malignant or benign?

    abstract::Solitary pulmonary nodules are usually identified on routine chest radiographs in asymptomatic patients. Most nodules have a benign cause, but bronchogenic carcinoma, metastases, and other malignant processes are important causes as well and must be excluded in differential diagnosis. Plain chest radiography, computed...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Dholakia S,Rappaport DC

    更新日期:1996-02-01 00:00:00

  • High-carbohydrate, high-fiber diet. Is it practical and effective in treating hyperlipidemia?

    abstract::More than one half of middle-aged Americans have undesirably high serum lipid levels. Diets high in fiber and carbohydrate and low in fat reduce serum lipid levels two to four times more than the widely recognized American Heart Association diet. High intake of soluble fiber is especially effective for lowering serum ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1987.11699970

    authors: Anderson JW,Gustafson NJ

    更新日期:1987-09-15 00:00:00

  • Beneficial effects resulting from thiazolidinediones for treatment of type 2 diabetes mellitus.

    abstract::Because new drugs continue to be developed, physicians treating patients with type 2 diabetes have a wide range of agents from which to choose. The newest class, the thiazolidinediones (TZDs), should be a mainstay of treatment for most patients with type 2 diabetes, because these agents reduce insulin resistance as we...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Bell DS

    更新日期:2003-05-01 00:00:00

  • Cost-effective laboratory testing.

    abstract::The increased utilization of diagnostic procedures has prompted interest in cost-effective laboratory testing. Clinically useful tests-useful in the sense that the patient benefits-are cost effective. The choice of test(s) is determined by the risks and benefits of proposed management. In practice, the first step in c...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1981.11715687

    authors: Burke MD

    更新日期:1981-02-01 00:00:00

  • Efficacy and safety of saxagliptin combination therapy in US patients with type 2 diabetes.

    abstract:BACKGROUND:The mechanism of action of dipeptidyl peptidase-4 inhibitors, such as saxagliptin, makes them suitable for combination therapy in type 2 diabetes mellitus (T2DM). Genetic, cultural, and environmental differences in individuals from different regions of the world may result in differences in treatment respons...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.3810/pgm.2011.07.2305

    authors: Karyekar C,Donovan M,Allen E,Fleming D,Ravichandran S,Chen R

    更新日期:2011-07-01 00:00:00

  • Basics of joint injection. General techniques and tips for safe, effective use.

    abstract::Successful joint and soft-tissue aspiration and injection rely on the physician's understanding of the indications, contraindications, and general techniques involved in these procedures. The procedures are generally well tolerated and can be used to treat many painful musculoskeletal and soft-tissue conditions. ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2001.01.834

    authors: Rifat SF,Moeller JL

    更新日期:2001-01-01 00:00:00

  • Urinary tract infections. Current approaches, future directions.

    abstract::Urinary tract infection (UTI) is a common problem that is distressing for patients and costly for the healthcare system. UTIs commonly affect young, sexually active women; the elderly; and patients who have predisposing factors, such as catheterization. Recurrent infections are likely to occur in all these patients gr...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.12.2000.suppl11.57

    authors: Colgan R,Hooton TM,Gupta K,Gomolin IH,Childs S,Gould M

    更新日期:2000-12-01 00:00:00

  • The balloon-tipped thermodilution catheter. Aspects of its clinical utility.

    abstract::The balloon-tipped thermodilution catheter (BTTC) is an expensive, labor-intensive technology that has moderate risks. The sensitivity and specificity of the three principal tests that it can perform have not yet been well defined for different patient groups. The BTTC allows the acquisition of mixed venous blood, fro...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1986.11699383

    authors: Desbiens NA

    更新日期:1986-05-01 00:00:00

  • Cervical spondylotic myelopathy. A diagnostic challenge in aging patients.

    abstract::Cervical spondylotic myelopathy remains a diagnostic and therapeutic challenge to physicians in a number of specialties. The diagnostic evaluation consists of a comprehensive neurologic and orthopedic examination supplemented by appropriate neurophysiologic and neuroradiologic studies. Currently, magnetic resonance im...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1990.11704741

    authors: Lehman LB

    更新日期:1990-09-01 00:00:00

  • Ten pitfalls in the proper management of patients with hyponatremia.

    abstract::Hyponatremia (serum sodium <135 mEq/L) is a common electrolyte disorder in community or hospitalized patients. Serum sodium levels should be corrected at a proper rate in patients with hyponatremia, since overcorrection of serum sodium levels is related to devastating neurologic consequences, such as the osmotic demye...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.2016.1186488

    authors: Filippatos TD,Liamis G,Elisaf MS

    更新日期:2016-06-01 00:00:00

  • Dermatologic emergencies.

    abstract::Preview Several dermatoses are potentially fatal, and the mortality rate for some is quite high; prompt recognition and treatment are essential. Dr Gannon's succinct discussions of pemphigus vulgaris, necrotizing fasciitis, toxic epidermal necrolysis, Stevens-Johnson syndrome, toxic shock syndrome, and urticaria and a...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1994.11945875

    authors: Gannon T

    更新日期:1994-07-01 00:00:00

  • Pharmacologic therapy of asthma.

    abstract::Asthma is treated by avoiding the precipitants of symptoms, by a trial of hyposensitization (immunotherapy) if the precipitant cannot be avoided, and principally by pharmacologic therapy. Acute attacks have been most widely treated with epinephrine, but adrenergic aerosol bronchodilators and aminophylline are being us...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1976.11714330

    authors: Ellis EF

    更新日期:1976-04-01 00:00:00

  • New treatments for rheumatoid arthritis. Available and upcoming slow-acting antirheumatic drugs.

    abstract::No single therapeutic agent has been found to be universally effective for rheumatoid arthritis, so regimens using combinations of drugs have become the rule. Recently, several new agents with unique mechanisms of action have been introduced and found to produce various degrees of clinical benefit. Among these agents ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.1999.10.1.703

    authors: Fye KH

    更新日期:1999-10-01 00:00:00

  • Dissection of dizziness: with emphasis on labyrinthine vertigo.

    abstract::The three most common types of vertiginous episodes area benign positional vertigo, postural vertigo, and endolymphatic hydrops. One of these conditions will be found in more than 90% of patients who present with vertigo as their main complaint. A clear understanding of the differences among these three entities will ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1981.11715757

    authors: Maragos NE,Neel HB 3rd,McDonald TJ

    更新日期:1981-05-01 00:00:00

  • Vaccination update. Hib, hepatitis, polio, varicella, influenza, pneumococcal and meningococcal disease.

    abstract::Immunization of infants and children is the most effective strategy for decreasing the incidence of some infectious diseases. Most invasive disease due to Haemophilus influenzae type b occurs before age 5 years, and routine vaccination of infants for hepatitis B is currently recommended because selective immunization ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Vetter RT,Johnson GM

    更新日期:1995-11-01 00:00:00

  • Effect of renal impairment on the pharmacokinetics, efficacy, and safety of albiglutide.

    abstract:BACKGROUND:Chronic kidney disease is frequently present in patients with type 2 diabetes mellitus (T2DM). New therapeutic options in this patient subpopulation are needed. OBJECTIVES:Assess the effect of renal impairment on the pharmacokinetics (PK), efficacy, and safety of albiglutide in single- and multiple-dose stu...

    journal_title:Postgraduate medicine

    pub_type: 临床试验,杂志文章

    doi:10.3810/pgm.2014.05.2754

    authors: Young MA,Wald JA,Matthews JE,Yang F,Reinhardt RR

    更新日期:2014-05-01 00:00:00

  • When is pulmonary artery catheterization worth the risks?

    abstract::Bedside pulmonary artery catheterization has proven to be an important addition to the clinical assessment of critically ill patients. Properly used, the procedure may provide hemodynamic information that is not apparent from physical examination or radiography. It may be safely accomplished through various venous rou...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1991.11700825

    authors: Zimmerman FH

    更新日期:1991-02-01 00:00:00

  • Evaluation of heart sounds and murmurs in children.

    abstract::Auscultation is the core of pediatric cardiovascular evaluation and should be performed according to a routine. The four heart sounds should be sought in order at their usual locations, with particular attention to the second sound because of its important diagnostic role in congenital cyanotic heart disease. The next...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1982.11716128

    authors: Kulangara RJ,Strong WB,Miller MD

    更新日期:1982-07-01 00:00:00

  • Penile lesions: a generalist's guide.

    abstract::Penile lesions are a discomfiting affliction demanding skillful diagnosis and management by the primary care physician. This article discusses and illustrates 14 common types, delineating characteristics, course, and treatment. ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1981.11715853

    authors: Witherington R

    更新日期:1981-09-01 00:00:00

  • Severe Pseudomonas aeruginosa infections. Tackling the conundrum of drug resistance.

    abstract::Pseudomonas aeruginosa infections are a frequent cause of morbidity and mortality in hospitalized patients. Treatment of these infections is complicated by the intrinsic and acquired resistance of this bacterium to many commonly used antimicrobial agents. In this article, Drs Hauser and Sriram argue that careful consi...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2005.01.1571

    authors: Hauser AR,Sriram P

    更新日期:2005-01-01 00:00:00

  • The patient experience with DSM-5-defined binge eating disorder: characteristics, barriers to treatment, and implications for primary care physicians.

    abstract:BACKGROUND:Binge eating disorder (BED) is now a formal diagnosis in the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5). However, post-DSM-5 patient profiles and viewpoints on BED diagnosis and treatment remain unclear. This study used a focus group methodology to examine demographic and cl...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.3810/pgm.2014.09.2800

    authors: Herman BK,Safikhani S,Hengerer D,Atkins N Jr,Kim A,Cassidy D,Babcock T,Agus S,Lenderking WR

    更新日期:2014-09-01 00:00:00

  • Septic arthritis. Clinical approach to the 'hot joint'.

    abstract::Joint space infections continue to be among the most common forms of arthritis. Diagnosis can be difficult, particularly in the presence of underlying joint disease. Septic arthritis should be suspected in all patients who present with an acutely swollen joint. Immediate joint aspiration with Gram's stain and culture ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1986.11699270

    authors: Evanchick CE,Davis DE,Harrington TM

    更新日期:1986-02-01 00:00:00