Indium 111 oxine-labeled leukocytes for early diagnosis of ischemic enterocolitis.

Abstract:

:The feasibility of the use of indium 111 oxine-labeled autologous leukocytes for the diagnosis of ischemic enterocolitis in vivo was examined in an experimental model of ischemia in dogs. A 30-cm segment of small intestine was devascularized by ligating the arteries and veins from the last arcade in 7 dogs. A sham operation was performed in 3 control dogs. 111In oxine-labeled autologous white blood cells were infused 3.5 hours after operation. Anterior and lateral nuclear scanning was performed at 6 and 24 hours postinfusion with a gamma camera equipped with a low-energy magnifying multihole collimator. The animals were killed after 24 hours. The gross and microscopic appearance of the bowel was evaluated. The radioactivity in the serial specimens of the bowel was measured. In vivo scans were positive (ie, increased uptake in the bowel loop) in all dogs with intestinal ischemia at 6 and 24 hours. No significant uptake was noted in control dogs. Rectilinear scan of the bowel removed at autopsy showed a correlation between the area of infarction and tracer accumulation. In addition, there was a progressive decrease in uptake of 111In oxine from the center of the ischemic lesions to the periphery. Forty percent of the total radioactivity was measured at the center of the lesion, whereas only 6.5% was present at 22.5 cm from the center. Thus the ratio between the ischemic and normal tissue was 10:1 (range, 6.5 to 16). These studies demonstrate that 111In oxine-labeled autologous white blood cells can be used for the diagnosis of ischemic enterocolitis.(ABSTRACT TRUNCATED AT 250 WORDS)

journal_name

J Pediatr Surg

authors

De Agustin J,Kalhan S,Grisoni E

doi

10.1016/0022-3468(91)90669-k

subject

Has Abstract

pub_date

1991-09-01 00:00:00

pages

1039-42

issue

9

eissn

0022-3468

issn

1531-5037

pii

0022-3468(91)90669-K

journal_volume

26

pub_type

杂志文章
  • Diaphragmatic hernia in the fetus: prenatal diagnosis and outcome in 94 cases.

    abstract::Most babies born with congenital diaphragmatic hernia (CDH) die after birth. The natural course of CDH in the human fetus is not known. We found 94 cases of fetal CDH in the records of surgeons and obstetricians surveyed in the United States and Canada. We found the following: (1) prenatal diagnosis of CDH is accurate...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/s0022-3468(85)80219-0

    authors: Adzick NS,Harrison MR,Glick PL,Nakayama DK,Manning FA,deLorimier AA

    更新日期:1985-08-01 00:00:00

  • A case of fibrous hamartoma of infancy.

    abstract::An instance of fibrous hamartoma of infancy (FHI) in the perianal region of an 8-mo-old infant, a hitherto unreported location, is described. The majority of the reported cases occur in the torso and upper extremities. The differential diagnostic features which aid differentiating FHI from other conditions is discusse...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/s0022-3468(79)80582-5

    authors: Albukerk J,Wexler H,Dana M,Silverman J

    更新日期:1979-02-01 00:00:00

  • Outcome of adrenocortical tumors in children.

    abstract:PURPOSE:This study reviews adrenocortical tumors in children to determine factors that significantly affect outcome. METHODS:An institutional review board-approved retrospective review from 1976 to 2005 identified 23 patients younger than 19 years old with histologic confirmation of adrenocortical carcinoma (ACC) and ...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2007.12.022

    authors: Hanna AM,Pham TH,Askegard-Giesmann JR,Grams JM,Iqbal CW,Stavlo P,Moir CR

    更新日期:2008-05-01 00:00:00

  • Response-based therapy for ruptured appendicitis reduces resource utilization.

    abstract:PURPOSE:We examined the effectiveness of a postoperative ruptured appendicitis protocol that eliminated Pseudomonas coverage and based the duration of IV antibiotic treatment and length of hospital stay on the patient's clinical response. METHODS:In our new protocol, IV antibiotics were administered until the patient ...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2014.09.012

    authors: Skarda DE,Schall K,Rollins M,Andrews S,Olson J,Greene T,McFadden M,Thorell EA,Barnhart D,Meyers R,Scaife E

    更新日期:2014-12-01 00:00:00

  • Preoperative bombesin administration can protect the rat small bowel allograft from ischemic reperfusion injury.

    abstract:BACKGROUND/PURPOSE:Ischemic reperfusion injury (IR/I) should be minimum for the success of small bowel transplantation (SBTx). This study investigated whether preoperative administration of neuropeptide bombesin (BBS) had a protective effect against IR/I and subsequent acute rejection. METHODS:Allogenic SBTx was perfo...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2005.08.035

    authors: Kinoshita H,Kimura O,Furukawa T,Higuchi K,Chujo S,Iwai N

    更新日期:2005-12-01 00:00:00

  • Nutritional morbidity in survivors of congenital diaphragmatic hernia.

    abstract:PURPOSE:The purpose of this report is to detail the nutritional sequelae seen in survivors of congenital diaphragmatic hernia (CDH) followed in a multidisciplinary clinic. METHODS:Data on 121 surviving CDH patients seen between 1990 and 2000 were collected. Regression analysis was used to determine the impact of facto...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1053/jpsu.2001.25746

    authors: Muratore CS,Utter S,Jaksic T,Lund DP,Wilson JM

    更新日期:2001-08-01 00:00:00

  • Avoiding misdiagnosing neuroblastoma as Wilms tumor.

    abstract:PURPOSE:Although occasionally difficult, distinguishing abdominal neuroblastoma (NBL) from Wilms tumor (WT) at presentation is important, as surgical management differs significantly. We reviewed our 20-year experience (1987-2006) treating patients with NBL, focusing on those with an initial diagnosis of WT, to determi...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2008.02.047

    authors: Dickson PV,Sims TL,Streck CJ,McCarville MB,Santana VM,McGregor LM,Furman WL,Davidoff AM

    更新日期:2008-06-01 00:00:00

  • Repair of mucosal perforation during pyloromyotomy: surgeon's choice.

    abstract::Mucosal perforation during Fredet-Ramstedt pyloromyotomy traditionally has been repaired with muscular and mucosal reapproximation, pyloric rotation, and repeat myotomy. The purpose of this study was to determine whether simple mucosal closure is a safe alternative repair technique for such a perforation. The authors ...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/0022-3468(95)90398-4

    authors: Royal RE,Linz DN,Gruppo DL,Ziegler MM

    更新日期:1995-10-01 00:00:00

  • Survival in a 2-year-old boy with hemorrhage secondary to an aortoesophageal fistula.

    abstract::Aortoesophageal fistula (AOF) in children with no history of cardiac disease or trauma is extremely rare, and survival is even rarer. We present a case of a 2-year-old boy who presented with massive hematemesis secondary to a primary aortoesophageal fistula and was found at endoscopy to have a submucosal hematoma. He ...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2011.09.054

    authors: Coates LJ,McNally J,Caputo M,Cusick E

    更新日期:2011-12-01 00:00:00

  • Hirschsprung's disease in the newborn.

    abstract::Hirschsprung's disease has become a more common cause of newborn intestinal obstruction in the past 30 years. In a group of 137 newborns with intestinal obstruction the most common diagnosis was necrotizing enterocolitis. The second most common cause, however, was Hirschsprung's disease. We have reviewed 26 infants wi...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/s0022-3468(84)80255-9

    authors: Klein MD,Coran AG,Wesley JR,Drongowski RA

    更新日期:1984-08-01 00:00:00

  • Cholelithiasis in childhood: a follow-up study.

    abstract::Fifteen children with cholelithiasis who were treated at the Royal Hospital for Sick Children, Glasgow between 1973 and 1985 are reviewed. Ten patients had idiopathic gallstones and five had gallstones in association with hereditary spherocytosis. All patients have been followed up for between 4 months and 12 years (m...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/s0022-3468(88)80732-2

    authors: Robertson JF,Carachi R,Sweet EM,Raine PA

    更新日期:1988-03-01 00:00:00

  • Anterior gastropexy prevents gastrostomy-induced gastroesophageal reflux: an experimental study in piglets.

    abstract::There is evidence that gastrostomy can induce gastroesophageal reflux (GER). We used pH monitoring in piglets to evaluate GER after gastrostomy and to assess the effect of anterior gastropexy. Oesophageal pH studies were performed before and after gastrostomy with (8) and without (9) anterior gastropexy. The reflux sc...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/0022-3468(91)90706-y

    authors: Heij HA,Seldenrijk CA,Vos A

    更新日期:1991-05-01 00:00:00

  • Urethral polyp in neonate: a rare occurrence.

    abstract::Polyps of urethra as well as those in an anterior urethra in a male neonate are a rare abnormality, hence this publication. They usually present as either obstructive urinary symptoms in males or as an intralabial mass in females (Raviv G, Leibovitch I, Hanani J, et al., Hematuria and voiding disorders in children cau...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2005.07.051

    authors: Sitapara A,Popat S

    更新日期:2005-11-01 00:00:00

  • Mycobacterial lymphadenitis.

    abstract::The plan for cervical lymph node biopsy should include special maneuvers for recognition of patients with lymphadenitis due to atypical mycobacteria, since these children need extensive operations. The diagnosis should be suspected in children less than 3 yr old with lymphadenopathy present for several months and no e...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/s0022-3468(82)80116-4

    authors: Harris BH,Webb HW,Wilkinson AH Jr,Santelices AA

    更新日期:1982-10-01 00:00:00

  • Angiolymphoid hyperplasia with eosinophilia on penile skin in a 7-year-old child.

    abstract::We report a case of a 7-year-old child who presented with a painless mass on his penis. He underwent removal of the mass, which was found to be an angiolymphoid hyperplasia with eosinophilia. Angiolymphoid hyperplasia with eosinophilia is an extremely rare tumor, especially in children's penis. In this situation, trea...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2010.12.009

    authors: Nishi M,Matsumoto K,Fujita T,Satoh T,Iwabuchi K,Iwamura M,Baba S

    更新日期:2011-03-01 00:00:00

  • Pathophysiology of aganglionic colon segment: an experimental study on aganglionosis produced by a new method in the rat.

    abstract::Experimental aganglionosis was produced successfully in a colonic segment proximal to the peritoneal reflection by intraluminal filling under tension of the colorectum of rats with 0.01% corrosive sublimate in normal saline solution. Where the length of aganglionic segment was more than 3 cm, ileus appeared and megaco...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/s0022-3468(75)80089-3

    authors: Imamura K,Yamamoto M,Sato A,Kashiki Y,Kunieda T

    更新日期:1975-12-01 00:00:00

  • Cervical teratomas: an analysis. Literature review and proposed classification.

    abstract::Cervical teratomas are uncommon lesions usually diagnosed at birth but occasionally reported in older children and adults. During a 58-year span, nine cervical teratomas were identified at our institution (four previously reported): three stillborns with giant tumors; five live newborns; and one adult with a malignant...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章,评审

    doi:10.1016/s0022-3468(88)80373-7

    authors: Jordan RB,Gauderer MW

    更新日期:1988-06-01 00:00:00

  • Pediatric trauma caused by personal watercraft: a ten-year retrospective.

    abstract:BACKGROUND/PURPOSE:Evidence indicates that young adults are at significant risk for powered personal watercraft (PWC)-related injuries. This article examines the nature of PWC injuries sustained in the pediatric population over a 10-year period. METHODS:Retrospective analysis was conducted of trauma registry charts on...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/s0022-3468(03)00507-4

    authors: Rubin LE,Stein PB,DiScala C,Grottkau BE

    更新日期:2003-10-01 00:00:00

  • Dumping syndrome following Nissen's fundoplication: a cause for refusal to feed.

    abstract::Two cases of infantile dumping syndrome which developed following Nissen fundoplication for gastroesophageal reflux are described. Both infants were fed postoperatively via a gastrostomy and showed the typical clinical picture of dumping with failure to thrive, intermittent diarrhea, lethargy and pallor postprandially...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/s0022-3468(84)80436-4

    authors: Hirsig J,Baals H,Tuchschmid P,Spitz L,Stauffer UG

    更新日期:1984-04-01 00:00:00

  • Hydrogen sulfide provides intestinal protection during a murine model of experimental necrotizing enterocolitis.

    abstract:BACKGROUND:Necrotizing enterocolitis (NEC) continues to be a morbid surgical condition among preterm infants. Novel therapies for this condition are desperately needed. Hydrogen sulfide (H2S) is an endogenous gasotransmitter that has been found to have beneficial properties. We therefore hypothesized that intraperitone...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2017.12.003

    authors: Drucker NA,Jensen AR,Ferkowicz M,Markel TA

    更新日期:2018-09-01 00:00:00

  • Tracheobronchial ruptures from blunt thoracic trauma in children.

    abstract:BACKGROUND/PURPOSE:Tracheobronchial ruptures in blunt thoracic trauma in children are rare. The aim of this study was to suggest the means of an early diagnosis and a conservative management as often as possible. METHODS:Sixteen cases of tracheobronchial ruptures by blunt thoracic trauma were observed over 26 years in...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/s0022-3468(99)90328-7

    authors: Slimane MA,Becmeur F,Aubert D,Bachy B,Varlet F,Chavrier Y,Daoud S,Fremond B,Guys JM,de Lagausie P,Aigrain Y,Reinberg O,Sauvage P

    更新日期:1999-12-01 00:00:00

  • Evaluation of Nissen fundoplication in neurologically impaired children.

    abstract::The value of performing Nissen fundoplication in neurologically impaired children is a controversial issue. To evaluate the benefit of fundoplication in these children, hospital records were reviewed for 77 children who underwent fundoplication for gastroesophageal reflux (GER). Fifty-two children were neurologically ...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/0022-3468(91)90013-j

    authors: Rice H,Seashore JH,Touloukian RJ

    更新日期:1991-06-01 00:00:00

  • Tracheoplasty with cartilage-engineered esophagus environments.

    abstract:PURPOSE:Our objective was to investigate the feasibility of engineering cartilage on the esophagus layer and outside the esophagus. Moreover, we investigated the feasibility of tracheoplasty with cartilage engineered on the esophagus in rabbits. METHODS:Chondrocytes were isolated from auricular cartilages. 1. Engineer...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2014.07.005

    authors: Komura M,Komura H,Otani Y,Suzuki K,Satake R,Kodaka T,Terawaki K,Yonekawa H,Ikebukuro K,Hoshi K,Takato T,Tabata Y,Komuro H,Iwanaka T

    更新日期:2015-07-01 00:00:00

  • The intestinal damage induced by lipid soluble meconium subfraction is profound compared to the intestinal damage induced by water soluble meconium subfraction.

    abstract:BACKGROUND:It is unclear which substances in meconium are responsible for intestinal damage in gastroschisis. An experimental study was designed to investigate the effects of the lipid or water soluble subfractions of meconium on the intestines of gastroschisis in a chick model. METHODS:Meconium was pooled, homogenate...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2016.02.088

    authors: Ulusoy O,Karakuş OZ,Ateş O,Hakgüder G,Özer E,Olguner M,Akgür FM

    更新日期:2016-08-01 00:00:00

  • Pubertal genitofemoral nerve division induces testicular ascent in adult rats.

    abstract:BACKGROUND/PURPOSE:Ascending testes, which normally are located at the bottom of the scrotum in early infancy and later ascend back out of the scrotum, have been reported by several investigators. However, little is known about the effect of the division of the genitofemoral nerve (GFN) on testicular ascent as boys gro...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/s0022-3468(99)90206-3

    authors: Shono T,Zakaria O,Imajima T,Suita S,Morimoto K

    更新日期:1999-02-01 00:00:00

  • Inhibition of heparin precipitation, bacterial growth, and fungal growth with a combined isopropanol-ethanol locking solution for vascular access devices.

    abstract:BACKGROUND:Clinical reports of ethanol-lock use for the prevention of catheter-related bloodstream infections have been marked by the occurrence of serious catheter occlusions, particularly among children with mediports. We hypothesized that precipitate forms when ethanol mixes with heparin at the concentrations releva...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2014.07.003

    authors: Restrepo D,Laconi NS,Alcantar NA,West LA,Buttice AL,Patel S,Kayton ML

    更新日期:2015-03-01 00:00:00

  • Management of nonparasitic splenic cysts in children: A French multicenter review of 100 cases.

    abstract:BACKGROUND:The management of nonparasitic splenic cysts (NPSC) remains controversial. Surgical resection is indicated for symptomatic or complicated forms, but no guidelines are available for asymptomatic NPSC. The aims of this study were to evaluate the management of NPSC in French hospitals and to analyze the results...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jpedsurg.2017.01.054

    authors: Delforge X,Chaussy Y,Borrego P,Abbo O,Sauvat F,Ballouhey Q,Irtan S,Arnaud A,Ibtissam K,Panait N,Rodesch G,Steyaert H,Schneider A,Dubois R,Mesureur S,Haraux E,Buisson P

    更新日期:2017-09-01 00:00:00

  • Initial laparoscopic appendectomy versus initial nonoperative management and interval appendectomy for perforated appendicitis with abscess: a prospective, randomized trial.

    abstract:INTRODUCTION:Perforated appendicitis is a common condition in children, which, in a small number of patients, may be complicated by a well-formed abscess. Initial nonoperative management with percutaneous drainage/aspiration of the abscess followed by intravenous antibiotics usually allows for an uneventful interval ap...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jpedsurg.2009.10.039

    authors: St Peter SD,Aguayo P,Fraser JD,Keckler SJ,Sharp SW,Leys CM,Murphy JP,Snyder CL,Sharp RJ,Andrews WS,Holcomb GW 3rd,Ostlie DJ

    更新日期:2010-01-01 00:00:00

  • Temporary fetal tracheal occlusion using a gel plug in a rabbit model of congenital diaphragmatic hernia.

    abstract:PURPOSE:Temporary tracheal occlusion induces lung growth in congenital diaphragmatic hernia (CDH) but has significant drawbacks because the device must be removed in utero. We devised a gel plug (GP) that can be placed in the fetal trachea in a rabbit model of CDH to provide temporary tracheal occlusion and evaluated i...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/j.jpedsurg.2012.03.005

    authors: Muensterer OJ,Nicola T,Farmer S,Harmon CM,Ambalavanan N

    更新日期:2012-06-01 00:00:00

  • Testicular feminization syndrome (androgen insensitivity).

    abstract::Three children with testicular feminization syndrome have been seen in the past 4 yr. Each presented with at least one large inguinal hernia. The gonad was proven to be a testis by frozen section. Gonadectomy and herniorrhaphy were done. The plan is to remove the second gonad after puberty. The causation and genetics ...

    journal_title:Journal of pediatric surgery

    pub_type: 杂志文章

    doi:10.1016/s0022-3468(81)80008-5

    authors: Marshall DG,Valentine GH

    更新日期:1981-08-01 00:00:00