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Revascularization technique for reduced-size liver transplantation for infants weighing less than 10 kg.

Abstract：

:Reduced-size liver transplantation has been recognized as a powerful modality in alleviating the global donor shortage in pediatric liver transplantation. We describe, for the first time, a technique for revascularizing reduced-size grafts which has not been patterned after adult revascularization techniques. This revascularization method for reduced-size liver transplantation is particularly suitable for infants weighing < 10 kg. This technique differs from adult revascularization techniques in that the supraceliac aorta is always used as the origin for graft arterialization, and that the anastomoses are always performed in the following order: end-to-side donor celiac artery to supraceliac aorta anastomoses first, followed by the suprahepatic vena caval anastomoses, infrahepatic vena caval anastomoses, and then portal vein anastomoses. Hepatic artery thrombosis in infants weighing < 10 kg has occurred in 4 of 32 nonreduced versus 0 of 21 reduced transplantations (P = .05616, Z test, one tail). Adult revascularization was primarily used in the nonreduced group, whereas our proposed revascularization method was primarily used in the reduced group. We conclude that, for infants weighing < 10 kg receiving reduced grafts, this proposed technique should be used to decrease hepatic artery thrombosis.

journal_name

J Pediatr Surg

journal_title

Journal of pediatric surgery

authors

Nakazato PZ,Cox KL,Concepcion W,Berquist WE,Esquivel CO

doi

10.1016/0022-3468(93)90698-k

subject

Has Abstract

pub_date

1993-07-01 00:00:00

pages

923-6

issue

7

eissn

0022-3468

issn

1531-5037

pii

S0022346893002866

journal_volume

28

pub_type

杂志文章

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