Analysis of fixed-ratio behavior maintained by drug reinforcers.

Abstract:

:Behavior maintained by intravenously delivered alfentanil, cocaine, or ketamine was assessed using a fixed-ratio schedule of reinforcement. As the dose of each drug was increased, rate of responding also increased up to a maximum. Further increases in dose resulted in decreased response rates (inverted U-shaped curve). An analysis of postreinforcement-pause-time and run-time measures for the ascending limb of the inverted U-shaped functions revealed that behavior was characterized by systematic decreases in both pause time and run time as dose and rate increased. An examination of the descending limb of the dose-response functions revealed that lowered response rates for cocaine and ketamine were correlated with increases in run time and small and inconsistent effects on postreinforcement pause time. Behavior maintained by rate-reducing doses of alfentanil was characterized by lengthened postreinforcement pauses with small increases in run time. These data suggest that at larger doses, drug reinforcers may have unconditioned or direct effects on the behavior that the drug is maintaining, and more important, that the nature of these unconditioned effects depends on the drug that is maintaining behavior.

journal_name

J Exp Anal Behav

authors

Skjoldager P,Winger G,Woods JH

doi

10.1901/jeab.1991.56-331

subject

Has Abstract

pub_date

1991-09-01 00:00:00

pages

331-43

issue

2

eissn

0022-5002

issn

1938-3711

journal_volume

56

pub_type

杂志文章
  • Effects of signaled and unsignaled shock on schedule-controlled lever pressing and schedule-induced licking: Shock intensity and body weight.

    abstract::Schedule-controlled lever pressing and schedule-induced licking were studied in rats under a multiple fixed-interval fixed-interval schedule of food reinforcement. Following acquisition of stable rates of pressing and licking, a multiple variable-time variable-time schedule of electric-shock delivery was superimposed ...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.1981.35-197

    authors: Hymowitz N

    更新日期:1981-03-01 00:00:00

  • Fixed ratio and extinction performance of infants in the second year of life.

    abstract::Five 14(1/2)- to 19(1/2)-month-old infants were trained to lever press for snacks on small fixed ratio schedules of reinforcement. Within four to nine sessions, responding under FR 10 was established for four subjects and FR 15 for the other. Each subject's last session revealed behavioral patterns similar to animal a...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.1966.9-105

    authors: Weisberg P,Fink E

    更新日期:1966-03-01 00:00:00

  • On the classic and modern theories of matching.

    abstract::Classic matching theory, which is based on Herrnstein's (1961) original matching equation and includes the well-known quantitative law of effect, is almost certainly false. The theory is logically inconsistent with known experimental findings, and experiments have shown that its central constant-k assumption is not te...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.2005.59-04

    authors: McDowell JJ

    更新日期:2005-07-01 00:00:00

  • On conditioned reinforcing effects of negative discriminative stimuli.

    abstract::Observing responses by pigeons were studied during sessions in which a food key and an observing key were available continuously. A variable-interval schedule and extinction alternated randomly on the food key. In one condition, food-key pecking during extinction decreased reinforcement frequency during the next varia...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.1989.52-335

    authors: Allen KD,Lattal KA

    更新日期:1989-11-01 00:00:00

  • The dynamics of the law of effect: a comparison of models.

    abstract::Dynamical models based on three steady-state equations for the law of effect were constructed under the assumption that behavior changes in proportion to the difference between current behavior and the equilibrium implied by current reinforcer rates. A comparison of dynamical models showed that a model based on Navaka...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.2010.93-91

    authors: Navakatikyan MA,Davison M

    更新日期:2010-01-01 00:00:00

  • Deviations from matching as a measure of preference for alternatives in pigeons.

    abstract::Preferences for larger or smaller defined response classes were investigated in a concurrent schedule precedure. Twelve pigeons were run on a series of concurrent variable-interval reinforcement schedules, from which baseline matching functions were obtained. An experimental phase followed, in which a second response ...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.1979.32-1

    authors: Leigland SM

    更新日期:1979-07-01 00:00:00

  • Magnitude and duration of the effects of cocaine on conditioned and adjunctive behaviors in the chimpanzee.

    abstract::Characteristic patterns of conditioned key-pressing were maintained in the chimpanzee under a multiple 30-response fixed-ratio, 10-minute fixed-interval schedule of food presentation. Adjunctive drinking occurred with regularity during the fixed-interval schedule and, with less frequency, during 1-minute timeout perio...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.1980.33-131

    authors: Byrd LD

    更新日期:1980-01-01 00:00:00

  • The effect of a pre-shock signal on a free-operant avoidance response.

    abstract::After 25 free-operant avoidance training sessions, a 1-min signal followed by a brief shock was presented on the average of once every 4 min. During the signal, the avoidance schedule was suspended (20 sessions). Response rates during the signal were markedly reduced. Shock rates during non-signalled periods increased...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.1970.14-331

    authors: Roberts AE,Hurwitz HM

    更新日期:1970-11-01 00:00:00

  • Recency, repeatability, and reinforcer retrenchment: an experimental analysis of resurgence.

    abstract::Four experiments were conducted with pigeons to assess the experimental conditions necessary for the occurrence of resurgence. The general procedure consisted of the following conditions: Condition 1--reinforcement of key pecking; Condition 2--reinforcement of treadle pressing and concurrent extinction of key pecking;...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.2003.80-217

    authors: Lieving GA,Lattal KA

    更新日期:2003-09-01 00:00:00

  • Stimulus-food relations and free-operant postponement of timeout from response-independent food presentation.

    abstract::Grain was briefly presented to food-deprived pigeons intermittently and response-independently except during signaled timeouts. During Experiment 1, key pecks postponed the next timeout for a specified interval. Rates of pecking during time in were inversely related to the length of time pecking postponed the next tim...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.1983.40-153

    authors: Galbicka G,Branch MN

    更新日期:1983-09-01 00:00:00

  • Effects of response preference on resistance to change.

    abstract::Treatments based on differential reinforcement of alternative behavior, such as functional communication training, are widely used. Research regarding the maintenance of related treatment effects is limited. Nevin and Wacker (2013) provided a conceptual framework, rooted in behavioral momentum theory, for the study of...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1002/jeab.308

    authors: Ringdahl JE,Berg WK,Wacker DP,Crook K,Molony MA,Vargo KK,Neurnberger JE,Zabala K,Taylor CJ

    更新日期:2018-01-01 00:00:00

  • Hierarchical classification as relational framing.

    abstract::The purpose of this study was to model hierarchical classification as contextually controlled, generalized relational responding or relational framing. In Experiment 1, a training procedure involving nonarbitrarily related multidimensional stimuli was used to establish two arbitrary shapes as contextual cues for 'memb...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1002/jeab.63

    authors: Slattery B,Stewart I

    更新日期:2014-01-01 00:00:00

  • Conditioning of within-trial patterns of key pecking in pigeons.

    abstract::The possibility of conditioning systematic patterns of responding during brief discrete trials was studied by requiring hungry pigeons to key peck and then pause or to pause and then key peck in order to gain access to food. These schedules were highly effective in promoting decelerated and accelerated rates of respon...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.1977.28-213

    authors: Wasserman EA

    更新日期:1977-11-01 00:00:00

  • Reponse-reinforcer independence and conventional extinction after fixed-interval and variable-interval schedules.

    abstract::After training three albino rats to bar press during a multiple fixed-interval variable-interval schedule, the response-reinforcer dependency was simultaneously removed from both components, converting the schedule to multiple fixed-time variable-time. Response rates were reduced in both components under these conditi...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.1972.18-133

    authors: Lattal KA

    更新日期:1972-07-01 00:00:00

  • Toward a unified theory of decision criterion learning in perceptual categorization.

    abstract::Optimal decision criterion placement maximizes expected reward and requires sensitivity to the category base rates (prior probabilities) and payoffs (costs and benefits of incorrect and correct responding). When base rates are unequal, human decision criterion is nearly optimal, but when payoffs are unequal, suboptima...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章,评审

    doi:10.1901/jeab.2002.78-567

    authors: Maddox WT

    更新日期:2002-11-01 00:00:00

  • Uninstructed human responding: Sensitivity of low-rate performance to schedule contingencies.

    abstract::College students' presses on a telegraph key occasionally turned on a light in the presence of which button presses produced points later exchangeable for money. Initially, responding was maintained by low-rate contingencies superimposed on either random-interval or random-ratio schedules. Later, the low-rate continge...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.1981.36-207

    authors: Shimoff E,Catania AC,Matthews BA

    更新日期:1981-09-01 00:00:00

  • Rats (Rattus norvegicus) find occupancy of a restraint tube rewarding.

    abstract::Two experiments evaluated whether rats' occupancy of a restraint tube is reinforcing. In Experiment 1, each rat in the 0-min group moved freely in a chamber where a wall blocked access to a restraint tube. After 10 min the wall was removed, permitting 15 min of chamber access and tube entry. The other 2 groups were lo...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1002/jeab.596

    authors: Hachiga Y,Silberberg A,Slotnick B,Gomez M

    更新日期:2020-05-01 00:00:00

  • Randomization procedures in single-case intervention research contexts: (Some of) "the rest of the story".

    abstract::Following up on articles recently published in this journal, the present contribution tells (some of) "the rest of the story" about the value of randomization in single-case intervention research investigations. Invoking principles of internal, statistical-conclusion, and external validity, we begin by emphasizing the...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1002/jeab.558

    authors: Levin JR,Kratochwill TR,Ferron JM

    更新日期:2019-11-01 00:00:00

  • Impulse control in pigeons.

    abstract::Pigeons were given a small, immediate food reinforcement for pecking a key, and a larger, delayed reinforcement for not pecking this key. Most subjects pecked the key on more than 95% of trials. However, when pecking a differently colored key at an earlier time prevented this option from becoming available, three of 1...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.1974.21-485

    authors: Ainslie GW

    更新日期:1974-05-01 00:00:00

  • The nature of control by spoken words over visual stimulus selection.

    abstract::Eight retarded adolescents were trained to select one (a trained S+) of two visual stimuli in response to a spoken word (a trained word). Two different visual stimuli alternated randomly as the S-. To determine if the spoken work was merely a temporal discriminative stimulus for when to respond, or if it also specifie...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.1977.27-433

    authors: Dixon LS

    更新日期:1977-05-01 00:00:00

  • Elicited responding in chain schedules.

    abstract::An omission procedure was employed to study elicited pecking in the first component of a two-component chain schedule. Both components were fixed-interval schedules correlated with colored keylights. The first response following the initial-link schedule produced a second fixed-interval schedule. We studied several fi...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.1991.56-475

    authors: Dougherty DM,Lewis P

    更新日期:1991-11-01 00:00:00

  • Differential antagonism of cocaine self-administration and cocaine-induced disruptions of learning by haloperidol in rhesus monkeys.

    abstract::Six rhesus monkeys responding under a three-component multiple schedule were administered haloperidol to determine its effects on cocaine self-administration and on cocaine's disruptive effects on the repeated acquisition and performance of response chains. In the absence of haloperidol, 0.0032-0.032 mg/kg/infusion of...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.2008.89-225

    authors: Winsauer PJ,Moerschbaecher JM,Roussell AM

    更新日期:2008-03-01 00:00:00

  • An alternative approach to calculating Area-Under-the-Curve (AUC) in delay discounting research.

    abstract::Applied to delay discounting data, Area-Under-the-Curve (AUC) provides an atheoretical index of the rate of delay discounting. The conventional method of calculating AUC, by summing the areas of the trapezoids formed by successive delay-indifference point pairings, does not account for the fact that most delay discoun...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1002/jeab.219

    authors: Borges AM,Kuang J,Milhorn H,Yi R

    更新日期:2016-09-01 00:00:00

  • Signal modality and choice between signaled and unsignaled food.

    abstract::Choice between signaled and unsignaled response-independent food schedules was assessed in three experiments using a commitment procedure. In Experiment 1, subjects tested with a 5-s visual signal consistently changed from the signaled to the unsignaled schedule. Changing from the unsignaled to the signaled schedule w...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.1984.42-279

    authors: Harsh J,Badia P,Ryan K

    更新日期:1984-09-01 00:00:00

  • Accuracy of discrimination, rate of responding, and resistance to change.

    abstract::Pigeons were trained on multiple schedules in which responding on a center key produced matching-to-sample trials according to the same variable-interval 30-s schedules in both components. Matching trials consisted of a vertical or tilted line sample on the center key followed by vertical and tilted comparisons on the...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.2003.79-307

    authors: Nevin JA,Milo J,Odum AL,Shahan TA

    更新日期:2003-05-01 00:00:00

  • Application of Bower's one-element model to paired-associate learning by pigeons.

    abstract::Bower's (1961) all-or-none model of human paired-associate learning was applied to individual data supplied by three pigeons. When the center one of three keys was illuminated with red light or with three white dots in a vertical array on a black ground, pecking on the left key was reinforced. When the center key was ...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.1973.19-219

    authors: Rodewald HK

    更新日期:1973-03-01 00:00:00

  • Conditional discrimination learning: a critique and amplification.

    abstract::Carter and Werner recently reviewed the literature on conditional discrimination learning by pigeons, which consists of studies of matching-to-sample and oddity-from-sample. They also discussed three models of such learning: the "multiple-rule" model (learning of stimulus-specific relations), the "configuration" model...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.1980.33-291

    authors: Schrier AM,Thompson CR

    更新日期:1980-03-01 00:00:00

  • Relations among acute and chronic nicotine administration, short-term memory, and tactics of data analysis.

    abstract::Emerging evidence suggests that nicotine may enhance short-term memory. Some of this evidence comes from nonhuman primate research using a procedure called delayed matching-to-sample, wherein the monkey is trained to select a comparison stimulus that matches some physical property of a previously presented sample stim...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.2012.98-155

    authors: Kangas BD,Branch MN

    更新日期:2012-09-01 00:00:00

  • THE OPPORTUNITY FOR AGGRESSION AS AN OPERANT REINFORCER DURING AVERSIVE STIMULATION.

    abstract::Squirrel monkeys were provided with a chain-pulling response which produced an inanimate object that could be attacked. In the absence of pain-shock, little or no chain-pulling occurred. When pain-shocks were delivered, chain-pulling responses increased. The chain-pulling response was successively reinforced, extingui...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.1965.8-171

    authors: AZRIN NH,HUTCHINSON RR,MCLAUGHLIN R

    更新日期:1965-05-01 00:00:00

  • Social learning by following: an analysis.

    abstract::Learning by "following", probably a common means by which behaviors are socially transmitted from adults to young in many species, was analyzed. Pigeons first learned to eat from a human hand. When the hand then approached an operant key and pecked it, the pigeons followed and quickly learned to do the same, thereby d...

    journal_title:Journal of the experimental analysis of behavior

    pub_type: 杂志文章

    doi:10.1901/jeab.1977.27-127

    authors: Bullock D,Neuringer A

    更新日期:1977-01-01 00:00:00