Abstract:
:A void volume fraction and fractions of mean sizes 800 kdalton and 300 kdalton were isolated by gel filtration from lysate of bovine erythrocytes infected with Babesia bovis. All fractions had good serological activity, as assayed by ELISA and IFA. Groups of four splenectomized calves were vaccinated with each fraction and then challenged, together with groups of four control calves, with a homologous strain of B. bovis. The group vaccinated with the 300 kdalton fraction showed some protection, as indicated by delayed and significantly lower parasitaemias and by a 75% survival in the group. In contrast, all animals in the relevant control group died from infection. No evident protection was obtained with the other two fractions.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Waltisbuhl DJ,Goodger BV,Wright IG,Mirre GB,Commins MAdoi
10.1007/BF00531085subject
Has Abstractpub_date
1987-01-01 00:00:00pages
319-23issue
4eissn
0932-0113issn
1432-1955journal_volume
73pub_type
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