Clinical and demographic characteristics of people who smoke versus inject crystalline methamphetamine in Australia: Findings from a pharmacotherapy trial.


INTRODUCTION AND AIMS:There has been a rapid increase in smoking crystalline methamphetamine in Australia. We compare the clinical and demographic characteristics of those who smoke versus inject the drug in a cohort of people who use methamphetamine. DESIGN AND METHODS:Participants (N = 151) were dependent on methamphetamine, aged 18-60 years, enrolled in a pharmacotherapy trial for methamphetamine dependence, and reported either injecting (n = 54) or smoking (n = 97) methamphetamine. Measures included the Timeline Followback, Severity of Dependence Scale, Amphetamine Withdrawal Questionnaire, Craving Experience Questionnaire and the Brief Psychiatric Rating Scale (symptoms of depression, hostility, psychosis and suicidality). Simultaneous regression was used to identify independent demographic correlates of smoking methamphetamine and to compare the clinical characteristics of participants who smoked versus injected. RESULTS:Compared to participants who injected methamphetamine, those who smoked methamphetamine were younger and less likely to be unemployed, have a prison history or live alone. Participants who smoked methamphetamine used methamphetamine on more days in the past 4 weeks than participants who injected methamphetamine (26 vs. 19 days, P = 0.001); they did not differ significantly in their severity of methamphetamine dependence, withdrawal, craving or psychiatric symptoms (P > 0.05). After adjustment for demographic differences, participants who smoked had lower craving [b (SE) = -1.1 (0.5), P = 0.021] and were less likely to report psychotic symptoms [b (SE) = -1.8 (0.7), P = 0.013] or antidepressant use [b (SE) = -1.1 (0.5), P = 0.022]. DISCUSSION AND CONCLUSIONS:Smoking crystalline methamphetamine is associated with a younger less marginalised demographic profile than injecting methamphetamine, but a similarly severe clinical profile.


Drug Alcohol Rev


Drug and alcohol review


McKETIN R,Quinn B,Higgs P,Berk M,Dean OM,Turner A,Kelly PJ,Lubman DI,Carter G,Baker AL,Manning V,Thomas T,Bathish R,Raftery D,Saunders L,Wrobel A,Meehan A,Sinclair B,Reid D,Arunogiri S,Hill H,Cordaro F,Dietze




Has Abstract


2020-10-06 00:00:00






  • Cannabis use in Cape York Indigenous communities: high prevalence, mental health impacts and the desire to quit.

    abstract:INTRODUCTION AND AIMS:Anecdotal reports suggest that high rates of cannabis use and dependence are significant issues in Indigenous communities in north Queensland; however, there is little scientific evidence to support or refute this. The Cape York Cannabis Project seeks to investigate cannabis use rates, cannabis de...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Bohanna I,Clough AR

    更新日期:2012-06-01 00:00:00

  • Self-limiting non-medical pharmaceutical opioid use among young people in Sydney, Australia: An exploratory study.

    abstract:INTRODUCTION AND AIMS:Indicators suggest an escalation in opioid use globally, with recent HIV outbreaks linked to non-medical pharmaceutical opioid (NMPO) use. Little is known about how young Australians engage in NMPO use. DESIGN AND METHODS:During 2015, we conducted qualitative interviews with young people (16-29 y...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Dertadian GC,Dixon TC,Iversen J,Maher L

    更新日期:2017-09-01 00:00:00

  • Predictors of 3-month retention in a drug treatment therapeutic community.

    abstract:INTRODUCTION AND AIMS:To study rates of 3-month retention in a drug treatment therapeutic community and the characteristics of residents who remain in treatment. DESIGN AND METHODS:A total of 200 consecutive admissions to a therapeutic community in Christchurch, New Zealand received a structured interview and question...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Mulder RT,Frampton CM,Peka H,Hampton G,Marsters T

    更新日期:2009-07-01 00:00:00

  • Family risk factors for cannabis use: a population-based survey of Australian secondary school students.

    abstract::The objective of this study was to investigate relationships between adolescent cannabis use and indices of parent - child attachment, family functioning and parent attitudes to drugs and delinquency. A total of 2848 year 9 and 2363 year 11 students participated in the Victorian Adolescent Health and Well-Being Survey...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Olsson CA,Coffey C,Toumbourou JW,Bond L,Thomas L,Patton G

    更新日期:2003-06-01 00:00:00

  • A brief motivational intervention for substance misuse in recent-onset psychosis.

    abstract::Substance misuse is common in early psychosis, and impacts negatively on outcomes. Little is known about effective interventions for this population. We report a pilot study of brief intervention for substance misuse in early psychosis (Start Over and Survive: SOS), comparing it with Standard Care (SC). Twenty-five in...

    journal_title:Drug and alcohol review

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Kavanagh DJ,Young R,White A,Saunders JB,Wallis J,Shockley N,Jenner L,Clair A

    更新日期:2004-06-01 00:00:00

  • The toxicology of homicide offenders and victims: A review.

    abstract:ISSUES:The toxicology of homicide offenders and victims, and homicide as a cause of death among psychoactive substance users. APPROACH:Review of the toxicology of homicide, and homicide as a cause of death among psychoactive substance users. KEY FINDINGS:A half or more of offenders are intoxicated by a psychoactive s...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章,评审


    authors: Darke S

    更新日期:2010-03-01 00:00:00

  • Effect of alcohol prohibition on liver cirrhosis mortality rates in Canada from 1901 to 1956: A time-series analysis.

    abstract:INTRODUCTION AND AIMS:The extent to which alcohol consumption in Canada was affected by alcohol prohibition in the early 20th century remains unclear. Since there is a dearth of data on consumption during this time, we estimated the effect of alcohol prohibition on alcohol consumption, as measured by changes in liver c...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Chrystoja BR,Rehm J,Crépault JF,Shield K

    更新日期:2020-09-01 00:00:00

  • Causes of death of patients with methamphetamine dependence: a record-linkage study.

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    journal_title:Drug and alcohol review

    pub_type: 杂志文章


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    更新日期:2011-11-01 00:00:00

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    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Bannan N,Rooney S,O'connor J

    更新日期:2007-01-01 00:00:00

  • Reviewing the needs of unemployed youth in smoking intervention programmes.

    abstract::In Australia, the impact of unemployment on adolescent smoking behaviour continues to present a major public health problem. Traditional prevention programmes in both primary and secondary schools appear to be achieving a delay in the onset of smoking. However, smoking rates of young people who are unemployed are unac...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Stanton WR,Gillespie AM,Lowe JB

    更新日期:1995-01-01 00:00:00

  • Gender differences in adolescents attending a drug and alcohol withdrawal service.

    abstract:INTRODUCTION AND AIMS:Gender differences have been reported in adult substance users, but little research has examined gender differences in adolescents presenting to treatment services. This study aimed to explore gender differences in adolescents presenting to a withdrawal service. DESIGN AND METHODS:All presentatio...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Dean AJ,McBride M,Macdonald EM,Connolly Y,McDermott BM

    更新日期:2010-05-01 00:00:00

  • A resounding success or a disastrous failure: re-examining the interpretation of evidence on the Portuguese decriminalisation of illicit drugs.

    abstract::In this Harm Reduction Digest two observers and scholars of the 2001 Portuguese drug policy reform consider divergent accounts of the reform which viewed it as a 'resounding success' or a 'disastrous failure'. Acknowledging from their own experience the inherent difficulties in studying drug law reform, Caitlin Hughes...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Hughes CE,Stevens A

    更新日期:2012-01-01 00:00:00

  • Adolescents drink less: How, who and why? A review of the recent research literature.

    abstract:ISSUES:Today's teenagers have been described as a sober generation and we asked: 'What is known about the recent decline in youth drinking?' APPROACH:A literature review (2005-2017). KEY FINDINGS:Research from wealthier parts of the world provides solid evidence of less alcohol use by youth since the millennium shift...

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    pub_type: 杂志文章,评审


    authors: Pape H,Rossow I,Brunborg GS

    更新日期:2018-04-01 00:00:00

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    abstract:INTRODUCTION AND AIMS:Studies link socio-economic deprivation to alcohol consumption in adolescents, but the role of relative deprivation has been understudied and may be equally important. This study investigates the association between relative deprivation and episodes of drunkenness among adolescents in France and C...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Sentenac M,Ehlinger V,Napoletano A,Spilka S,Gariepy G,Godeau E,Elgar FJ

    更新日期:2017-11-01 00:00:00

  • The nature and strength of the relationship between expenditure on alcohol and food: an analysis of adult-only households in the UK.

    abstract:INTRODUCTION AND AIMS:Unhealthy lifestyle behaviours can cluster to produce more detrimental overall health consequences than expected with a simple additive effect. This study aims to expand current knowledge of the nature and strength of the relationship between two such health behaviours, alcohol and diet, through a...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Gell L,Meier P

    更新日期:2012-06-01 00:00:00

  • Do public expenditures on health and families relate to alcohol abstaining in adolescents? Multilevel study of adolescents in 24 countries.

    abstract:INTRODUCTION AND AIMS:Several European countries have observed an increase in the proportion of adolescents that abstain from drinking alcohol in the last decade. The reasons for this trend remain underexplored. We hypothesised that more generous government expenditures on health services and benefits to families with ...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Vieno A,Altoè G,Kuntsche E,Elgar FJ

    更新日期:2018-04-01 00:00:00

  • A systematic review of computerised serious educational games about alcohol and other drugs for adolescents.

    abstract:ISSUES:Serious educational games (SEG) have been shown to be effective in educating young people about a range of topics, including languages and maths. This paper identifies the use of computerised SEGs in education about alcohol and other drugs and reviews their impact on the prevention of alcohol and drug use. APPR...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章,评审


    authors: Rodriguez DM,Teesson M,Newton NC

    更新日期:2014-03-01 00:00:00

  • Surge in treatment admissions related to methamphetamine use in Cape Town, South Africa: implications for public health.

    abstract:INTRODUCTION AND AIMS:In the past decade, methamphetamine has become increasingly a drug of concern globally. The purpose of this study is to describe the changing trends in treatment admissions for methamphetamine abuse in Cape Town, South Africa and to highlight the implications of these changes for policy, practice ...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Plüddemann A,Myers BJ,Parry CD

    更新日期:2008-03-01 00:00:00

  • Wonderland and the rabbit hole: A commentary on university students' alcohol use during first year and the early transition to university.

    abstract::For new students, university can be a wonderland of opportunity. But the first few weeks of the university experience are also typified by change, stress and uncertainty. From a health promotion perspective, the first few weeks of the university experience present an important yet understudied opportunity for alcohol ...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章,评审


    authors: Riordan BC,Carey KB

    更新日期:2019-01-01 00:00:00

  • Diagnosis-based emergency department alcohol harm surveillance: What can it tell us about acute alcohol harms at the population level?

    abstract:INTRODUCTION AND AIMS:Acute harm from heavy drinking episodes is an increasing focus of public health policy, but capturing timely data on acute harms in the population is challenging. This study aimed to evaluate the precision of readily available administrative emergency department (ED) data in public health surveill...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Whitlam G,Dinh M,Rodgers C,Muscatello DJ,McGuire R,Ryan T,Thackway S

    更新日期:2016-11-01 00:00:00

  • Issues with recruitment to randomised controlled trials in the drug and alcohol field: a literature review and Australian case study.

    abstract:ISSUES:The randomised control trial (RCT) is a widely used tool for measuring the effectiveness of health treatments and services. However, subject recruitment is an ongoing challenge for those conducting RCTs and may have a serious impact on the success of the study and the reliability of the outcomes. APPROACH:In th...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章,评审


    authors: Thomson CL,Morley KC,Teesson M,Sannibale C,Haber PS

    更新日期:2008-03-01 00:00:00

  • Novel psychoactive substance use by US adolescents: Characteristics associated with use of synthetic cannabinoids and synthetic cathinones.

    abstract:INTRODUCTION AND AIMS:The current study documents the characteristics associated with the use of two novel psychoactive substances: synthetic cannabinoids and synthetic cathinones. DESIGN AND METHODS:Nationally representative samples of students in 8th (n = 9665), 10th (n = 10 655) and 12th (n = 10 057) grades across ...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Patrick ME,O'Malley PM,Kloska DD,Schulenberg JE,Johnston LD,Miech RA,Bachman JG

    更新日期:2016-09-01 00:00:00

  • Pathophysiologic mechanisms responsible for the reversible (thiamine-responsive) and irreversible (thiamine non-responsive) neurological symptoms of Wernicke's encephalopathy.

    abstract::Chronic alcoholism results in thiamine deficiency as a result of poor nutrition and impaired gastrointestinal absorption of the vitamin. Pyrithiamine-induced thiamine deficiency in the rat reproduces a neurological syndrome and ultimately neuropathological damage of a nature and distribution that is similar to that en...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Butterworth RF

    更新日期:1993-01-01 00:00:00

  • An overview of take-home naloxone programs in Australia.

    abstract:INTRODUCTION AND AIMS:Take-home naloxone (THN) programs commenced in Australia in 2012 in the Australian Capital Territory and programs now operate in five Australian jurisdictions. The purpose of this paper is to record the progress of THN programs in Australia, to provide a resource for others wanting to start THN pr...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Dwyer R,Olsen A,Fowlie C,Gough C,van Beek I,Jauncey M,Lintzeris N,Oh G,Dicka J,Fry CL,Hayllar J,Lenton S

    更新日期:2018-05-01 00:00:00

  • Detection of problem-drinkers in an emergency department using a breathalyser and questionnaire.

    abstract::Over a 2-week period in January 1990 consecutive adult emergency attenders were breathalysed and screened for problem drinking using the WHO screening instrument. Results were compared with a similar study conducted 8 years previously. Of the patients tested, 12.5% had a positive alcohol in 1990 compared with 16% in 1...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Robinson GM,Leslie H,Robinson BJ

    更新日期:1992-01-01 00:00:00

  • Health and well-being outcomes for drug-dependent offenders on the NSW Drug Court programme.

    abstract::Given the centrality of drug treatment to the drug court framework, the proliferation of drug courts in the United States, and their emergence more recently in Australia, it is surprising that such little attention has been given to assessing their therapeutic effect. This evaluation aimed to assess the health and wel...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Freeman K

    更新日期:2003-12-01 00:00:00

  • The Finnish drinking culture: change and continuity in the past 40 years.

    abstract:INTRODUCTION AND AIMS:In the past 40 years, per capita consumption has increased dramatically in Finland. We study the core changes in drinking culture over this period by age and sex. DESIGN AND METHODS:We used data from the Finnish Drinking Habit Surveys carried out every 8 years in 1968-2008 (n = 16385, response ra...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Mäkelä P,Tigerstedt C,Mustonen H

    更新日期:2012-11-01 00:00:00

  • From opioid maintenance to abstinence: a literature review.

    abstract::It appears that the literature on agonist maintenance therapies for opioid dependence pays more attention to outcomes during, rather than after, treatment. This review aims to (a) estimate to what extent opioid abstinence can be expected from former maintenance patients, (b) examine possible relationships between pati...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章,评审


    authors: Kornør H,Waal H

    更新日期:2005-05-01 00:00:00

  • Stopping petrol sniffing in remote Aboriginal Australia: key elements of the Mt Theo Program.

    abstract::Petrol sniffing is a major form of substance misuse in Aboriginal communities across Australia. This practice has detrimental effects on the health and wellbeing of individual sniffers, their families, communities and wider society. There are few examples of programmes that have successfully stopped petrol sniffing. T...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Preuss K,Brown JN

    更新日期:2006-05-01 00:00:00

  • Trends in methamphetamine use in young injection drug users in San Francisco from 1998 to 2004: the UFO Study.

    abstract:AIMS:To describe temporal trends in methamphetamine use among young injection drug users (IDU) in San Francisco. DESIGN AND METHODS:Secondary analysis of cross-sectional baseline data collected for a longitudinal study of young IDU from 1998 to 2004. Participants were 1445 young IDU (<30 years old) who reported inject...

    journal_title:Drug and alcohol review

    pub_type: 杂志文章


    authors: Inglez-Dias A,Hahn JA,Lum PJ,Evans J,Davidson P,Page-Shafer K

    更新日期:2008-05-01 00:00:00