Abstract:
:In this paper, we study quorum sensing in Pseudomonas aeruginosa biofilms. Quorum sensing is a process where bacteria monitor their population density through the release of extra-cellular signalling molecules. The presence of these molecules affects gene modulation leading to changes in behaviour such as the release of virulence factors. Here, we use numerical methods to approximate a 2-D model of quorum sensing. It is observed that the shape of the biofilm can have a profound effect on the onset of quorum sensing. This has serious repercussions for experimental observations since biofilms of the same biomass but different shapes can produce quite different results.
journal_name
Bull Math Bioljournal_title
Bulletin of mathematical biologyauthors
Vaughan BL Jr,Smith BG,Chopp DLdoi
10.1007/s11538-009-9485-8subject
Has Abstractpub_date
2010-07-01 00:00:00pages
1143-65issue
5eissn
0092-8240issn
1522-9602journal_volume
72pub_type
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