Abstract：
:The feasibility of using extended-release injectable naltrexone (XR-NTX) to treat alcohol dependence in routine primary care settings is unknown. An open-label, observational cohort study evaluated 3-month treatment retention, patient satisfaction, and alcohol use among alcohol-dependent patients in two urban public hospital medical clinics. Adults seeking treatment were offered monthly medical management (MM) and three XR-NTX injections (380 mg, intramuscular). Physician-delivered MM emphasized alcohol abstinence, medication effects, and accessing mutual help and counseling resources. Seventy-two alcohol-dependent patients were enrolled; 90% (65 of 72) of eligible subjects received the first XR-NTX injection; 75% (49 of 65) initiating treatment received the second XR-NTX injection; 62% (40 of 65), the third. Among the 56% (n = 40) receiving three injections, median drinks per day decreased from 4.1 (95% confidence interval = 2.9-6) at baseline to 0.5 (0-1.7) during Month 3. Extended-release naltrexone delivered in a primary care MM model appears a feasible and acceptable treatment for alcohol dependence.
journal_name
J Subst Abuse Treatjournal_title
Journal of substance abuse treatmentauthors
Lee JD,Grossman E,DiRocco D,Truncali A,Hanley K,Stevens D,Rotrosen J,Gourevitch MNdoi
10.1016/j.jsat.2010.03.005subject
Has Abstractpub_date
2010-07-01 00:00:00pages
14-21issue
1eissn
0740-5472issn
1873-6483pii
S0740-5472(10)00066-8journal_volume
39pub_type
杂志文章abstract：:It is a common belief that a massive effort in law enforcement, preventive education and rehabilitation will result in the elimination of a country's drug problem. Based on this premise. Malaysia in 1983 implemented such a multifaceted anti-drug strategy, and the results of a 1987 study by the author suggested that Ma...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/0740-5472(92)90087-5
更新日期：1992-01-01 00:00:00
abstract：:Attaining altered states of consciousness is described as a basic human motive. The substance dependent population is distinguished from other populations because they pursue these states destructively by inappropriate use of alcohol and drugs. Despite a body of literature supporting the benefits of altered states of ...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,评审
doi：10.1016/0740-5472(91)90030-e
更新日期：1991-01-01 00:00:00
abstract：:For many individuals, substance use leads to a chronic cycle of relapse, treatment reentry, and recovery, often lasting for decades. This study replicates earlier work, documents the transition patterns within the cycle during a 3-year period, and identifies variables that predict these transitions. Data are from 1,32...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2004.09.006
更新日期：2005-01-01 00:00:00
abstract：:In his extraordinarily productive research career, G. Alan Marlatt contributed to and anticipated by decades a variety of major changes in the treatment of substance use disorders. This article briefly reviews and comments on his contributions to addiction psychology, cognitive-behavior therapy, alcohol expectancies, ...
journal_title：Journal of substance abuse treatment
pub_type： 传,历史文章,杂志文章
doi：10.1016/j.jsat.2011.06.004
更新日期：2011-12-01 00:00:00
abstract：:Two nonspecific organizational factors-consensus, defined as agreement within staff and client groups, and concordance, defined as agreement between staff and client groups-were shown to influence client engagement in treatment in a national sample of 80 residential substance abuse treatment programs including 595 sta...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jsat.2006.05.002
更新日期：2006-10-01 00:00:00
abstract：BACKGROUND:Co-occurring mental health disorders are common among substance use disorder (SUD) patients. Medicaid expansion aimed to reduce barriers to SUD and mental health care and thereby improve treatment outcomes. METHODS:We estimated change in the proportion of United States SUD treatment sites offering treatment...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2019.07.012
更新日期：2019-10-01 00:00:00
abstract：:This study examined the efficacy of brief alcohol intervention in the context of community-based treatment for partner violence. In a randomized clinical trial, 228 partner-violent men with hazardous or problem drinking were recruited at three Intimate Partner Violence (IPV) treatment agencies and randomly assigned to...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jsat.2018.03.004
更新日期：2018-06-01 00:00:00
abstract：BACKGROUND:Early treatment motivation is a meaningful predictor of clinical outcomes in the context of methamphetamine dependence (MD). Cognitive deficits associated with MD can have a significant impact on motivational fluctuations during early treatment. We specifically examined if sustained attention and effort-base...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2018.09.007
更新日期：2018-12-01 00:00:00
abstract：:Overdose education and naloxone distribution (OEND) is an intervention that addresses overdose, but has not been studied among people who take methadone, a drug involved in increasing numbers of overdoses. This study describes the implementation of OEND among people taking methadone in the previous 30 days in various ...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2012.07.004
更新日期：2013-02-01 00:00:00
abstract：:Patients receiving inpatient treatment for alcohol dependence were followed for 31 weeks after discharge. Alcoholics Anonymous (AA) attenders, when compared with nonattenders, were not distinguishable on pretreatment patient characteristics. Posttreatment attendance of AA was not predictive of drinking outcomes. Howev...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/0740-5472(95)00018-z
更新日期：1995-07-01 00:00:00
abstract：:To determine how effective a modified therapeutic community (TC) with enhanced mental health staffing would be in treating mentally ill chemical abusing (MICA) clients in a "mainstream" program, Project Return Foundation, Inc. (PRF) conducted a treatment outcome evaluation study involving 438 residents. Client admissi...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/s0740-5472(98)00005-1
更新日期：1998-11-01 00:00:00
abstract：:The current study provides an initial examination of lapse and relapse to marijuana use among 82 individuals who achieved at least 2 weeks of abstinence during outpatient treatment for marijuana dependence. Seventy-one percent used marijuana at least once (i.e., lapsed) within 6 months of initial abstinence, averaging...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/s0740-5472(03)00083-7
更新日期：2003-09-01 00:00:00
abstract：:The purpose of this paper is to report a descriptive study of the degree of concordance between male alcoholics' and their wives' perceptions of the alcoholics' relapse to drinking within two years of their participation in an outcome study of behavioral marital therapy for alcoholism. At the end of a two-year follow-...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/0740-5472(88)90007-4
更新日期：1988-01-01 00:00:00
abstract：:Patient views of the helpful aspects of treatment were examined in the NIDA Collaborative Cocaine Treatment Study, a multi-site trial comparing four psychosocial treatments: individual cognitive therapy (CT), individual supportive expressive dynamic therapy (SE), individual drug counseling, and group drug counseling o...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jsat.2004.06.007
更新日期：2004-09-01 00:00:00
abstract：:The comorbidity of substance use disorder (SUD), depression, and PTSD is common among veterans. Prior research has shown that among veterans with SUD and depression, those with PTSD did not maintain cognitive-behavioral treatment gains as well as those without PTSD. Thus, the current study was designed to evaluate whe...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2015.11.005
更新日期：2016-03-01 00:00:00
abstract：:This study examined the impact of a computer simulation designed to provide the opportunity for individuals with alcohol use disorders (AUDs) to practice relapse prevention skills. Participants were 41 male veterans enrolled in an intensive outpatient substance abuse treatment program. Participants were randomly assig...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jsat.2012.08.006
更新日期：2013-03-01 00:00:00
abstract：:The goal of this study was to compare the effects of 1, 3 and 8 mg per day doses of buprenorphine in the maintenance treatment of opium-dependent subjects in Iran over a treatment period of 12 months. Participants were randomized to three equal groups (171 subjects per group) of opium-dependent individuals who met the...
journal_title：Journal of substance abuse treatment
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0740-5472(03)00141-7
更新日期：2004-01-01 00:00:00
abstract：:Following research indicating that the treatment needs of women are different from those of men, researchers and clinicians have argued that drug treatment programs for women should be designed to take their needs into account. Such programs tend to admit only women and incorporate philosophies and activities that are...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2010.12.001
更新日期：2011-06-01 00:00:00
abstract：:This article critically examines the literature which suggests that families of narcotic addicts push their addicted member toward death. Following an overview of the conventional literature on the family treatment of drug addiction, an alternative perspective is proposed to more fully understand how these families ar...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/0740-5472(87)90007-9
更新日期：1987-01-01 00:00:00
abstract：:Benzodiazepine use is prevalent. Moreover, benzodiazepine abuse, addiction, tolerance, and dependence occur commonly with benzodiazepine use. Confusion arises in assessing the nature and magnitude of benzodiazepine use and its consequences. Abuse, addiction, tolerance, and dependence occur in medical and nonmedical po...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,评审
doi：10.1016/0740-5472(91)90021-2
更新日期：1991-01-01 00:00:00
abstract：INTRODUCTION:Rapid HIV testing (RHT) greatly increases the proportion of clients who learn their test results. However, existing studies have not examined the adoption and implementation of RHT in programs treating persons with substance use disorders, one of the population groups at higher risk for HIV infection. MET...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2015.12.001
更新日期：2016-04-01 00:00:00
abstract：:This article examines some of the differential diagnostic considerations associated with the interaction between advanced cocaine psychosis and the neuropsychiatric manifestations of AIDS-Spectrum Disorders. A clinical case is presented to illustrate the potential for institutional countertransference in the treatment...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,评审
doi：10.1016/0740-5472(88)90031-1
更新日期：1988-01-01 00:00:00
abstract：:The Washington Circle (a multiple-disciplinary group of providers, researchers, managed care representatives, and public policy representatives) examined three performance measures for alcohol and other drug (AOD) services. These measures, which were developed and applied to managed care organizations' administrative ...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/s0740-5472(02)00303-3
更新日期：2002-12-01 00:00:00
abstract：:Greater impulsivity, assessed by the Barratt Impulsiveness Scale-11 (BIS-11) and Stroop interference scores, has been associated with treatment completion in cocaine-dependent patients. This study evaluated the relationships among impulsivity, stimulant-dependence diagnosis, and treatment completion. Six sites evaluat...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.jsat.2012.12.005
更新日期：2013-05-01 00:00:00
abstract：:In the context of the COVID-19 pandemic and the state of emergency that the government of Spain declared, the rapid adaptation of health services is of paramount importance to preserve access to and continuity of service delivery. This research note underscores the importance of ensuring a sufficient quantity of metha...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2020.108154
更新日期：2020-12-01 00:00:00
abstract：BACKGROUND:In non-pregnant individuals being treated for opioid use disorder (OUD) with methadone, doses ≥60mg per day are associated with improved treatment retention and decreased illicit opioid use. Although methadone remains the first line treatment for OUD in pregnant women, there are no studies replicating this f...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2017.06.005
更新日期：2017-09-01 00:00:00
abstract：:Recognition of valuable natural resources suggests a need to accept a degree of responsibility to preserve and nurture the commodity, and to prevent its destruction. Health care professionals generally embrace such an ethic with reference to the environment, the quality of living for clients, and the need to assume pr...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/0740-5472(84)90032-1
更新日期：1984-01-01 00:00:00
abstract：:Mothers who are physically and/or psychologically dependent upon alcohol and illicit drugs are at risk for a wide range of parenting deficits beginning when their children are infants and continuing as their children move through school-age and adolescent years. Behavioral parent training programs for drug-dependent m...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章
doi：10.1016/j.jsat.2004.06.008
更新日期：2004-10-01 00:00:00
abstract：:We review the problems unique to the diagnosis and treatment of patients who suffer both major mental illness and alcohol/drug abuse. We describe the experience and the approach evolved in the Special Treatment Team, a State Hospital unit that has specialized in this work. We discuss in detail the assessment and stabi...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,评审
doi：10.1016/0740-5472(88)90044-x
更新日期：1988-01-01 00:00:00
abstract：:In the light of the attachment theory and research outlines the authors develop the concept that addiction is a delayed maladaptive attachment transition in young adults. They look into the relevance of this theoretical framework for therapy in adulthood, especially addiction therapy, connect it with an approach, that...
journal_title：Journal of substance abuse treatment
pub_type： 杂志文章,评审
doi：10.1016/s0740-5472(96)00156-0
更新日期：1996-11-01 00:00:00
