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Impulsivity is associated with treatment non-completion in cocaine- and methamphetamine-dependent patients but differs in nature as a function of stimulant-dependence diagnosis.

Abstract：

:Greater impulsivity, assessed by the Barratt Impulsiveness Scale-11 (BIS-11) and Stroop interference scores, has been associated with treatment completion in cocaine-dependent patients. This study evaluated the relationships among impulsivity, stimulant-dependence diagnosis, and treatment completion. Six sites evaluating 12-step facilitation for stimulant abusers obtained the BIS-11 and Stroop from 182 methamphetamine- and/or cocaine-dependent participants. Methamphetamine-dependent, relative to cocaine-dependent, participants evidenced significantly greater BIS-11 non-planning and total scores. There was a trend for poorer response inhibition, measured by the Stroop, in cocaine-dependent, relative to methamphetamine-dependent, participants. Accounting for other factors related to treatment completion, BIS-11 motor score, assessing the tendency to act without thinking, predicted treatment completion for both cocaine-dependent and methamphetamine-dependent patients. These results suggest that methamphetamine-dependent and cocaine-dependent patients may have different impulsivity profiles but that the BIS-11 may be useful in identifying both methamphetamine-dependent and cocaine-dependent patients who are at risk for treatment non-completion.

journal_name

J Subst Abuse Treat

journal_title

Journal of substance abuse treatment

authors

Winhusen T,Lewis D,Adinoff B,Brigham G,Kropp F,Donovan DM,Seamans CL,Hodgkins CC,Dicenzo JC,Botero CL,Jones DR,Somoza E

doi

10.1016/j.jsat.2012.12.005

subject

Has Abstract

pub_date

2013-05-01 00:00:00

pages

541-7

issue

5

eissn

0740-5472

issn

1873-6483

pii

S0740-5472(12)00453-9

journal_volume

44

pub_type

杂志文章,多中心研究,随机对照试验

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