Low nucleotide diversity for the expanded organelle and nuclear genomes of Volvox carteri supports the mutational-hazard hypothesis.

Abstract:

:The noncoding-DNA content of organelle and nuclear genomes can vary immensely. Both adaptive and nonadaptive explanations for this variation have been proposed. This study addresses a nonadaptive explanation called the mutational-hazard hypothesis and applies it to the mitochondrial, plastid, and nuclear genomes of the multicellular green alga Volvox carteri. Given the expanded architecture of the V. carteri organelle and nuclear genomes (60-85% noncoding DNA), the mutational-hazard hypothesis would predict them to have less silent-site nucleotide diversity (π(silent)) than their more compact counterparts from other eukaryotes-ultimately reflecting differences in 2N(g)μ (twice the effective number of genes per locus in the population times the mutation rate). The data presented here support this prediction: Analyses of mitochondrial, plastid, and nuclear DNAs from seven V. carteri forma nagariensis geographical isolates reveal low values of π(silent) (0.00038, 0.00065, and 0.00528, respectively), much lower values than those previously observed for the more compact organelle and nuclear DNAs of Chlamydomonas reinhardtii (a close relative of V. carteri). We conclude that the large noncoding-DNA content of the V. carteri genomes is best explained by the mutational-hazard hypothesis and speculate that the shift from unicellular to multicellular life in the ancestor that gave rise to V. carteri contributed to a low V. carteri population size and thus a reduced 2N(g)μ. Complete mitochondrial and plastid genome maps for V. carteri are also presented and compared with those of C. reinhardtii.

journal_name

Mol Biol Evol

authors

Smith DR,Lee RW

doi

10.1093/molbev/msq110

subject

Has Abstract

pub_date

2010-10-01 00:00:00

pages

2244-56

issue

10

eissn

0737-4038

issn

1537-1719

pii

msq110

journal_volume

27

pub_type

杂志文章
  • Symbiotic origin of a novel actin gene in the cryptophyte Pyrenomonas helgolandii.

    abstract::Cryptophytes are photosynthetic protists that have acquired their plastids through the secondary symbiotic uptake of a red alga. A remarkable feature of cryptophytes is that they maintain a reduced form of the red algal nucleus, the nucleomorph, between the second and third plastid membranes (periplastidial compartmen...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.molbev.a026271

    authors: Stibitz TB,Keeling PJ,Bhattacharya D

    更新日期:2000-11-01 00:00:00

  • Natural selection and the molecular clock.

    abstract::This paper concludes that the statistical properties of protein evolution are compatible with a particular model of evolution by natural selection. The argument begins with a statistical description of the molecular clock based on a Poisson process with a randomly varying tick rate. If the time scale of the change of ...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.molbev.a040382

    authors: Gillespie JH

    更新日期:1986-03-01 00:00:00

  • Molecular clocks do not support the Cambrian explosion.

    abstract::The fossil record has long supported the view that most animal phyla originated during a brief period approximately 520 MYA known as the Cambrian explosion. However, molecular data analyses over the past 3 decades have found deeper divergences among animals (approximately 800 to 1,200 MYA), with and without the assump...

    journal_title:Molecular biology and evolution

    pub_type: 信件

    doi:10.1093/molbev/msi039

    authors: Blair JE,Hedges SB

    更新日期:2005-03-01 00:00:00

  • High resolution mapping of candidate alleles for desiccation resistance in Drosophila melanogaster under selection.

    abstract::The ability to counter periods of low humidity is an important determinant of distribution range in Drosophila. Climate specialists with low physiological tolerance to desiccation stress are restricted to the tropics and may lack the ability to further increase resistance through evolution. Although the physiological ...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/molbev/msr294

    authors: Telonis-Scott M,Gane M,DeGaris S,Sgrò CM,Hoffmann AA

    更新日期:2012-05-01 00:00:00

  • Nontoxic strains of cyanobacteria are the result of major gene deletion events induced by a transposable element.

    abstract::Blooms that are formed by cyanobacteria consist of toxic and nontoxic strains. The mechanisms that result in the occurrence of nontoxic strains are enigmatic. All the nontoxic strains of the filamentous cyanobacterium Planktothrix that were isolated from 9 European countries were found to have lost 90% of a large micr...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/molbev/msn120

    authors: Christiansen G,Molitor C,Philmus B,Kurmayer R

    更新日期:2008-08-01 00:00:00

  • Progressive and Biased Divergent Evolution Underpins the Origin and Diversification of Peridinin Dinoflagellate Plastids.

    abstract::Dinoflagellates are algae of tremendous importance to ecosystems and to public health. The cell biology and genome organization of dinoflagellate species is highly unusual. For example, the plastid genomes of peridinin-containing dinoflagellates encode only a minimal number of genes arranged on small elements termed "...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/molbev/msw235

    authors: Dorrell RG,Klinger CM,Newby RJ,Butterfield ER,Richardson E,Dacks JB,Howe CJ,Nisbet ER,Bowler C

    更新日期:2017-02-01 00:00:00

  • Evolutionary instability of operon structures disclosed by sequence comparisons of complete microbial genomes.

    abstract::Gene orders have been shown to be generally unstable by comprehensive analyses in several complete genomes. In this study, we examined instability of genome structures within operons, where functionally related genes are clustered. We compared gene orders of known operons obtained from Escherichia coli and Bacillus su...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.molbev.a026114

    authors: Itoh T,Takemoto K,Mori H,Gojobori T

    更新日期:1999-03-01 00:00:00

  • Estimating selection pressures from limited comparative data.

    abstract::We recently introduced a novel method for estimating selection pressures on proteins, termed "volatility," which requires only a single genome sequence. Some criticisms that have been levied against this approach are valid, but many others are based on misconceptions of volatility, or they apply equally to comparative...

    journal_title:Molecular biology and evolution

    pub_type: 信件

    doi:10.1093/molbev/msl021

    authors: Plotkin JB,Dushoff J,Desai MM,Fraser HB

    更新日期:2006-08-01 00:00:00

  • Making the impossible possible: rooting the tree of placental mammals.

    abstract::Untangling the root of the evolutionary tree of placental mammals has been nearly an impossible task. The good news is that only three possibilities are seriously considered. The bad news is that all three possibilities are seriously considered. Paleontologists favor a root anchored by Xenarthra (e.g., sloths and ante...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/molbev/mst118

    authors: Teeling EC,Hedges SB

    更新日期:2013-09-01 00:00:00

  • Detection of convergent and parallel evolution at the amino acid sequence level.

    abstract::Adaptive evolution at the molecular level can be studied by detecting convergent and parallel evolution at the amino acid sequence level. For a set of homologous protein sequences, the ancestral amino acids at all interior nodes of the phylogenetic tree of the proteins can be statistically inferred. The amino acid sit...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.molbev.a025789

    authors: Zhang J,Kumar S

    更新日期:1997-05-01 00:00:00

  • The Legacy of Sexual Ancestors in Phenotypic Variability, Gene Expression, and Homoeolog Regulation of Asexual Hybrids and Polyploids.

    abstract::Hybridization and polyploidization are important evolutionary processes whose impacts range from the alteration of gene expression and phenotypic variation to the triggering of asexual reproduction. We investigated fishes of the Cobitis taenia-elongatoides hybrid complex, which allowed us to disentangle the direct eff...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/molbev/msz114

    authors: Bartoš O,Röslein J,Kotusz J,Paces J,Pekárik L,Petrtýl M,Halačka K,Štefková Kašparová E,Mendel J,Boroń A,Juchno D,Leska A,Jablonska O,Benes V,Šídová M,Janko K

    更新日期:2019-09-01 00:00:00

  • A phylogenetic mixture model for the evolution of gene expression.

    abstract::Microarray platforms are used increasingly to make comparative inferences through genome-wide surveys of gene expression. Although recent studies focus on describing the evidence for natural selection using estimates of the within- and between-taxa mutational variances, these methods do not explicitly or flexibly acco...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/molbev/msp149

    authors: Eng KH,Bravo HC,Keleş S

    更新日期:2009-10-01 00:00:00

  • Molecular reconstruction of extinct LINE-1 elements and their interaction with nonautonomous elements.

    abstract::Non-long terminal repeat retroelements continue to impact the human genome through cis-activity of long interspersed element-1 (LINE-1 or L1) and trans-mobilization of Alu. Current activity is dominated by modern subfamilies of these elements, leaving behind an evolutionary graveyard of extinct Alu and L1 subfamilies....

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/molbev/mss202

    authors: Wagstaff BJ,Kroutter EN,Derbes RS,Belancio VP,Roy-Engel AM

    更新日期:2013-01-01 00:00:00

  • Pervasive Phenotypic Impact of a Large Nonrecombining Introgressed Region in Yeast.

    abstract::To explore the origin of the diversity observed in natural populations, many studies have investigated the relationship between genotype and phenotype. In yeast species, especially in Saccharomyces cerevisiae, these studies are mainly conducted using recombinant offspring derived from two genetically diverse isolates,...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/molbev/msaa101

    authors: Brion C,Caradec C,Pflieger D,Friedrich A,Schacherer J

    更新日期:2020-09-01 00:00:00

  • The transition to self-compatibility in Arabidopsis thaliana and evolution within S-haplotypes over 10 Myr.

    abstract::A recent investigation found evidence that the transition of Arabidopsis thaliana from ancestral self-incompatibility (SI) to full self-compatibility occurred very recently and suggested that this occurred through a selective fixation of a nonfunctional allele (PsiSCR1) at the SCR gene, which determines pollen specifi...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/molbev/msl042

    authors: Bechsgaard JS,Castric V,Charlesworth D,Vekemans X,Schierup MH

    更新日期:2006-09-01 00:00:00

  • The number of alleles at a microsatellite defines the allele frequency spectrum and facilitates fast accurate estimation of theta.

    abstract::Theoretical work focused on microsatellite variation has produced a number of important results, including the expected distribution of repeat sizes and the expected squared difference in repeat size between two randomly selected samples. However, closed-form expressions for the sampling distribution and frequency spe...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/molbev/msq164

    authors: Haasl RJ,Payseur BA

    更新日期:2010-12-01 00:00:00

  • Assessing horizontal transfer of nifHDK genes in eubacteria: nucleotide sequence of nifK from Frankia strain HFPCcI3.

    abstract::The structural genes for nitrogenase, nifK, nifD, and nifH, are crucial for nitrogen fixation. Previous phylogenetic analysis of the amino acid sequence of nifH suggested that this gene had been horizontally transferred from a proteobacterium to the gram-positive/cyanobacterial clade, although the confounding effects ...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.molbev.a040184

    authors: Hirsch AM,McKhann HI,Reddy A,Liao J,Fang Y,Marshall CR

    更新日期:1995-01-01 00:00:00

  • Structural Patching Fosters Divergence of Mitochondrial Ribosomes.

    abstract::Mitochondrial ribosomes (mitoribosomes) are essential components of all mitochondria that synthesize proteins encoded by the mitochondrial genome. Unlike other ribosomes, mitoribosomes are highly variable across species. The basis for this diversity is not known. Here, we examine the composition and evolutionary histo...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/molbev/msy221

    authors: Petrov AS,Wood EC,Bernier CR,Norris AM,Brown A,Amunts A

    更新日期:2019-02-01 00:00:00

  • Cytonuclear Coevolution following Homoploid Hybrid Speciation in Aegilops tauschii.

    abstract::The diploid D-genome lineage of the Triticum/Aegilops complex has an evolutionary history involving genomic contributions from ancient A- and B/S-genome species. We explored here the possible cytonuclear evolutionary responses to this history of hybridization. Phylogenetic analysis of chloroplast DNAs indicates that t...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/molbev/msy215

    authors: Li C,Sun X,Conover JL,Zhang Z,Wang J,Wang X,Deng X,Wang H,Liu B,Wendel JF,Gong L

    更新日期:2019-02-01 00:00:00

  • The Amount of Nitrogen Used for Photosynthesis Modulates Molecular Evolution in Plants.

    abstract::Genome and transcript sequences are composed of long strings of nucleotide monomers (A, C, G, and T/U) that require different quantities of nitrogen atoms for biosynthesis. Here, it is shown that the strength of selection acting on transcript nitrogen content is influenced by the amount of nitrogen plants require to c...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/molbev/msy043

    authors: Kelly S

    更新日期:2018-07-01 00:00:00

  • Mitochondrial DNA in the sea urchin Arbacia lixula: evolutionary inferences from nucleotide sequence analysis.

    abstract::From the stirodont Arbacia lixula we determined the sequence of 5,127 nucleotides of mitochondrial DNA (mtDNA) encompassing 18 tRNAs, two complete coding genes, parts of three other coding genes, and part of the 12S ribosomal RNA (rRNA). The sequence confirms that the organization of mtDNA is conserved within echinoid...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.molbev.a040661

    authors: De Giorgi C,Lanave C,Musci MD,Saccone C

    更新日期:1991-07-01 00:00:00

  • Nineteenth century seeds reveal the population genetics of landrace barley (Hordeum vulgare).

    abstract::Barley (Hordeum vulgare) is a major crop, grown worldwide and in a wide range of climatic conditions. Despite its importance as a crop species, little is known about the population genetics of barley and the effects of bottlenecks, adaptation, and gene flow on genetic diversity within and between landrace populations....

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/molbev/msp308

    authors: Leino MW,Hagenblad J

    更新日期:2010-04-01 00:00:00

  • MitoFish and MiFish Pipeline: A Mitochondrial Genome Database of Fish with an Analysis Pipeline for Environmental DNA Metabarcoding.

    abstract::Fish mitochondrial genome (mitogenome) data form a fundamental basis for revealing vertebrate evolution and hydrosphere ecology. Here, we report recent functional updates of MitoFish, which is a database of fish mitogenomes with a precise annotation pipeline MitoAnnotator. Most importantly, we describe implementation ...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/molbev/msy074

    authors: Sato Y,Miya M,Fukunaga T,Sado T,Iwasaki W

    更新日期:2018-06-01 00:00:00

  • Gene regulatory divergence among species estimated by altered developmental patterns in interspecific hybrids.

    abstract::Disturbances in the schedules of gene expression in developing interspecific fish hybrids have been used to draw inferences about the extent of gene regulatory divergence between species and about the degree to which this gene regulatory divergence is correlated with structural gene divergence, as estimated by genetic...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章,评审

    doi:10.1093/oxfordjournals.molbev.a040349

    authors: Parker HR,Philipp DP,Whitt GS

    更新日期:1985-05-01 00:00:00

  • Origin of Nogo-A by domain shuffling in an early jawed vertebrate.

    abstract::Unlike mammals, fish are able to regenerate axons in their central nervous system. This difference has been partly attributed to the loss/acquisition of inhibitory proteins during evolution. Nogo-A--the longest isoform of the reticulon4 (rtn4) gene product--is commonly found in mammalian myelin where it acts as a pote...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/molbev/msq313

    authors: Shypitsyna A,Málaga-Trillo E,Reuter A,Stuermer CA

    更新日期:2011-04-01 00:00:00

  • Genomic Analyses Reveal Potential Independent Adaptation to High Altitude in Tibetan Chickens.

    abstract::Much like other indigenous domesticated animals, Tibetan chickens living at high altitudes (2,200-4,100 m) show specific physiological adaptations to the extreme environmental conditions of the Tibetan Plateau, but the genetic bases of these adaptations are not well characterized. Here, we assembled a de novo genome o...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/molbev/msv071

    authors: Wang MS,Li Y,Peng MS,Zhong L,Wang ZJ,Li QY,Tu XL,Dong Y,Zhu CL,Wang L,Yang MM,Wu SF,Miao YW,Liu JP,Irwin DM,Wang W,Wu DD,Zhang YP

    更新日期:2015-07-01 00:00:00

  • The relative contributions of recombination and mutation to the divergence of clones of Neisseria meningitidis.

    abstract::Multilocus sequence typing (MLST) is a recently developed nucleotide sequence-based method for the definitive assignment of isolates within bacterial populations to specific clones. MLST uses the same principles as multilocus enzyme electrophoresis and provides data that can be used to investigate aspects of the popul...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.molbev.a026061

    authors: Feil EJ,Maiden MC,Achtman M,Spratt BG

    更新日期:1999-11-01 00:00:00

  • A critical assessment of storytelling: gene ontology categories and the importance of validating genomic scans.

    abstract::In the age of whole-genome population genetics, so-called genomic scan studies often conclude with a long list of putatively selected loci. These lists are then further scrutinized to annotate these regions by gene function, corresponding biological processes, expression levels, or gene networks. Such annotations are ...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/molbev/mss136

    authors: Pavlidis P,Jensen JD,Stephan W,Stamatakis A

    更新日期:2012-10-01 00:00:00

  • Structure of the Transcriptional Regulatory Network Correlates with Regulatory Divergence in Drosophila.

    abstract::Transcriptional control of gene expression is regulated by biochemical interactions between cis-regulatory DNA sequences and trans-acting factors that form complex regulatory networks. Genetic changes affecting both cis- and trans-acting sequences in these networks have been shown to alter patterns of gene expression ...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/molbev/msx068

    authors: Yang B,Wittkopp PJ

    更新日期:2017-06-01 00:00:00

  • Odorant Receptors for Detecting Flowering Plant Cues Are Functionally Conserved across Moths and Butterflies.

    abstract::Odorant receptors (ORs) are essential for plant-insect interactions. However, despite the global impacts of Lepidoptera (moths and butterflies) as major herbivores and pollinators, little functional data is available about Lepidoptera ORs involved in plant volatile detection. Here, we initially characterized the plant...

    journal_title:Molecular biology and evolution

    pub_type: 杂志文章

    doi:10.1093/molbev/msaa300

    authors: Guo M,Du L,Chen Q,Feng Y,Zhang J,Zhang X,Tian K,Cao S,Huang T,Jacquin-Joly E,Wang G,Liu Y

    更新日期:2020-11-24 00:00:00