A systematic assessment of cardiovascular outcomes in the saxagliptin drug development program for type 2 diabetes.

abstract：:Oat cell carcinoma is the one variety of primary lung cancer which is sufficiently responsive to a variety of drugs and drug combinations that a very high rate of response and significant prolongation of survival can be consistently achieved. The question of whether anyone has been "cured" by drug treatment awaits mor...

journal_title：Postgraduate medicine

authors： Golbey RB

更新日期：1978-02-01 00:00:00

abstract：:Lactose intolerance is a common condition that can cause nonspecific gastrointestinal symptoms. A reliable diagnosis cannot be made on the basis of the patient's history. The breath hydrogen test is simple, noninvasive, accurate, and inexpensive and is the diagnostic method of choice. In addition to traditional dietar...

journal_title：Postgraduate medicine

authors： Montes RG,Perman JA

更新日期：1991-06-01 00:00:00

abstract：:Exercise-induced bronchospasm is a common complication of asthma. Aggressive treatment of this conditions permits patients to maintain full activity despite their illness. Since most asthmatic patients are healthy except for an intermittent respiratory problem, providing them the opportunity to exercise in all weather...

journal_title：Postgraduate medicine

authors： Brook CJ

更新日期：1992-02-15 00:00:00

abstract：:The cultural drive to be thin can lead to eating disorders in many women and girls. In adolescent females with diabetes, the increased focus on eating and the weight gain associated with good glycemic control likely increase their susceptibility to abnormal eating. It is clear that nonspecified and subthreshold eating...

journal_title：Postgraduate medicine

authors： Hoffman RP

更新日期：2001-04-01 00:00:00

abstract：:Treating rheumatoid arthritis can be very satisfying when patients participate fully in designing and implementing their therapeutic strategy. However, the strategy's success depends on early intervention and disease modification. Many patients do well when education, rest, diet, exercise, and drug therapy are incorpo...

journal_title：Postgraduate medicine

authors： Gremillion RB,van Vollenhoven RF

更新日期：1998-02-01 00:00:00

abstract：:Hoarseness indicates an abnormality at the level of the glottis. This symptom may result from either structural or physiologic disorders. The differential diagnosis is lengthy and includes both benign and malignant diseases. History taking and physical examination, particularly laryngeal visualization, provide key clu...

journal_title：Postgraduate medicine

authors： Dettelbach M,Eibling DE,Johnson JT

更新日期：1994-04-01 00:00:00

abstract：:Liver transplantation revolutionized the management of liver disease. Although the number of patients who could benefit from a transplant far exceeds the number of available cadaveric donors, new strategies, such as splitting cadaveric organs and using living donors, have expanded access to transplantation. Here, a te...

journal_title：Postgraduate medicine

authors： Tran TT,Nissen N,Poordad FF,Martin P

更新日期：2004-05-01 00:00:00

abstract：:Patients with chronic obstructive lung disease (COLD) experience one or more episodes of acute respiratory failure in the late years of their illness. Initial evaluation is aimed at assessing the precipitating factor or factors as well as the severity of the acute episode and the need for intubation and mechanical ven...

journal_title：Postgraduate medicine

authors： Francis PB

更新日期：1986-01-01 00:00:00

abstract：:The tools and methods of epidemiology, particularly the clinical trial, help guide the clinical practice of medicine. Dr Gorelick reviews the results of major clinical trials for prevention of transient cerebral ischemia and atherothrombotic stroke and assesses the effect of these findings on treatment. ...

journal_title：Postgraduate medicine

authors： Gorelick PB

更新日期：1989-12-01 00:00:00

abstract：:Nephrolithiasis is caused by several biochemical mechanisms, identification of which allows specific therapy that may prevent recurrences. In patients with their first kidney stone, careful evaluation is needed to identify those at highest risk for recurrence. Extensive evaluation of this subgroup should lead to prope...

journal_title：Postgraduate medicine

authors： Trivedi BK

更新日期：1996-12-01 00:00:00

abstract：INTRODUCTION:Over the past 2 decades, there has been a significant increase in the number of incidentally found small renal cortical neoplasms (RCNs). As more RCNs are being discovered in the elderly and infirmed patient populations, there has been a growing interest in the role of active surveillance (AS). Active surv...

journal_title：Postgraduate medicine

authors： Graversen JA,Mues AC,Pérez-Lanzac de Lorca A,Landman J

更新日期：2011-01-01 00:00:00

abstract：:The new oral anticoagulants have many advantages over vitamin K antagonists, but they are still associated with a troublesome incidence of major bleeding. Additionally, the absence of a reversal agent for the new oral anticoagulants is a barrier to their more widespread use. Currently, there are 3 potential reversal a...

journal_title：Postgraduate medicine

authors： Costin J,Ansell J,Laulicht B,Bakhru S,Steiner S

更新日期：2014-11-01 00:00:00

abstract：:When confronted with a patient with an alteration in mental status following surgery, the physician must consider both organic and psychosocial causes and their synergistic interactions. A careful medical assessment will rule out metabolic disorders, sepsis, cardiopulmonary complications, and adverse drug effects. A m...

journal_title：Postgraduate medicine

authors： Thompson TL 2nd,Feinberg LE

更新日期：1980-03-01 00:00:00

abstract：:Granulomatous inflammation of the peritoneal surfaces resulting from exposure to cornstarch granules from surgical gloves produces a syndrome of abdominal pair, adynamic ileus, fever, peritonitis, variable white blood cell count, and inflammatory ascites. Symptoms develop three to four weeks after a routine abdominal ...

journal_title：Postgraduate medicine

authors： Berkow AE

更新日期：1976-01-01 00:00:00

abstract：:The recent resurgence of rheumatic fever reported in eight locations in the United States after years of decline has several noteworthy characteristics. Most patients were children of families in high- to middle-income brackets with ready access to medical care. In four of the outbreaks, the majority of patients were ...

journal_title：Postgraduate medicine

authors： Ayoub EM

更新日期：1992-09-01 00:00:00

abstract：:Allergy is responsible for many problems in the pediatric age-group. At times the most difficult job for the physician is to determine if the patient is indeed allergic and, if so, to what. Allergy skin testing remains the first choice for diagnostic study. Treatment consists of avoiding the offending allergen if poss...

journal_title：Postgraduate medicine

authors： Hein EW,Kishore R

更新日期：1984-05-01 00:00:00

abstract：:Two cases of Listeria monocytogenes infection in patients receiving immunosuppressive treatment after kidney transplantation are described. In the first, the infection, which occurred soon after transplantation and was accompanied by signs of mild chronic rejection, was the immediate cause of death. The other case occ...

journal_title：Postgraduate medicine

authors： Holden FA,Kaczmer JE,Kinahan CC

更新日期：1980-12-01 00:00:00

abstract：:Not all of the costs of private practice, particularly those related to government regulation, are within your control. However, there are steps, both large and small, that you can take to get fees under control and to eliminate or reduce expenditures. Dr Orient suggests a number of these. ...

journal_title：Postgraduate medicine

authors： Orient JM

更新日期：1994-02-15 00:00:00

abstract：:Primary care physicians play an important role in the outpatient evaluation of proteinuria, a common finding in everyday medical practice. Therefore, it is important to recognize which symptoms and signs signal the need for further evaluation. A simple urine dipstick test usually is the first step, but factors leading...

journal_title：Postgraduate medicine

authors： Ali H

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:To evaluate healthcare resource utilization (HCRU) by osteoarthritis (OA) pain severity. METHODS:Cross-sectional surveys of US physicians and their patients were conducted between February and May 2017. Using the Numeric Rating Scale, patients were classified by self-reported pain intensity in the last week ...

journal_title：Postgraduate medicine

authors： Nalamachu S,Robinson RL,Viktrup L,Cappelleri JC,Bushmakin AG,Tive L,Mellor J,Hatchell N,Jackson J

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:There is a need to identify safe and effective opioid-sparing multimodal alternative treatment strategies and approaches, including topical analgesics, for opioid-experienced chronic pain patients to mitigate the risk of addiction, misuse, and abuse of opioids. METHODS:This subset analysis from a prospective...

journal_title：Postgraduate medicine

authors： Gudin JA,Brennan MJ,Harris ED,Hurwitz PL,Dietze DT,Strader JD

更新日期：2018-01-01 00:00:00

abstract：:Nitroglycerin and long-acting nitrates are the pharmacologic mainstays of antianginal therapy, both for acute attacks and for prophylaxis. Propranolol is often effective for prophylaxis in patients incompletely helped by nitrates. A holistic approach is stressed. Appropriate drug use will effect marked improvement in ...

journal_title：Postgraduate medicine

authors： Richtsmeier TE,Preston TA

更新日期：1977-11-01 00:00:00

abstract：OBJECTIVES:There are no evidence-based recommendations to screen for iron deficiency in non-anemic patients, even though symptoms may be present. The aim of this study is to measure the prevalence of iron deficiency (ID) without anemia in the general population aged 18-50 presenting to primary care along with the incid...

journal_title：Postgraduate medicine

authors： Abuaisha M,Itani H,El Masri R,Antoun J

更新日期：2020-04-01 00:00:00

abstract：:Is the degree of risk involved in providing health care to people infected with human immunodeficiency virus (HIV) acceptable? Every health care worker, even if only for a few anxious minutes, has certainly worried about this risk. Drs Wilson, Williams, and Robinson discuss these concerns and summarize the indications...

journal_title：Postgraduate medicine

authors： Wilson SE,Williams RA,Robinson G

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:The mechanism of action of dipeptidyl peptidase-4 inhibitors, such as saxagliptin, makes them suitable for combination therapy in type 2 diabetes mellitus (T2DM). Genetic, cultural, and environmental differences in individuals from different regions of the world may result in differences in treatment respons...

journal_title：Postgraduate medicine

authors： Karyekar C,Donovan M,Allen E,Fleming D,Ravichandran S,Chen R

更新日期：2011-07-01 00:00:00

abstract：:In a series of 123 children with disorders of defecation, constipation was the main problem in 89 and fecal incontinence in 34. All but three of the latter also had constipation. The principal physical findings were abdominal protuberance with palpable stool in the bowel and the presence of a fecal mass in the rectal ...

journal_title：Postgraduate medicine

authors： Liebman WM

更新日期：1979-08-01 00:00:00

abstract：:Although leprosy is increasing in incidence in the United States, it is confined almost entirely to immigrants from developing countries and their close contacts. While the clinical disease has not changed, leprosy has diffused more widely throughout the United States as a result of migration. Primary care physicians ...

journal_title：Postgraduate medicine

authors： Pust RE,Campos-Outcalt D

更新日期：1985-04-01 00:00:00

abstract：:Measurement of cerebrospinal fluid (CSF) lactate is a useful test when properly applied to the appropriate clinical situation and can offer information other CSF parameters cannot provide. Except for Gram's stain of CSF, lactate level is the most important CSF parameter in the early differentiation of viral (aseptic) ...

journal_title：Postgraduate medicine

authors： Bailey EM,Domenico P,Cunha BA

更新日期：1990-10-01 00:00:00

abstract：:Modern prospective trials have recently shown that warfarin prescribed to produce less anticoagulant effect than was customary in the past reduces cardioembolic stroke by up to 80% in patients with nonvalvular atrial fibrillation. These results represent a major advance in stroke prevention. The effectiveness of antit...

journal_title：Postgraduate medicine

authors： Anderson DC

更新日期：1991-12-01 00:00:00

abstract：:Recent effectiveness studies have shown that over a year and a half, 3 of 4 study patients either stopped or changed their antipsychotic medication. This finding highlights the fact that psychopharmacologic treatments do not remain stable over the course of treatment. Our own interpretation is that these findings emph...

journal_title：Postgraduate medicine

authors： Scheifler PL,Weiden PJ

更新日期：2006-09-01 00:00:00