Abstract:
:The peri-operative and postoperative effects of propofol given by infusion were compared with halothane as a supplement to nitrous oxide-oxygen anaesthesia for body surface surgery in patients who breathed spontaneously. Anaesthesia was induced after opioid premedication, with either propofol 2.5 mg/kg or thiopentone 4-5 mg/kg which were followed respectively by an infusion of propofol 12 mg/kg/hour for 10 minutes and at a variable rate thereafter, or by halothane at a mean inspired concentration of 1.2%. Maintenance of anaesthesia required a median rate of infusion of propofol of 149.4 micrograms/kg/minute. The cardiovascular effects during induction and maintenance of anaesthesia were similar in the two groups. The overall incidence of side effects was low but immediate recovery was significantly faster in patients who received propofol.
journal_name
Anaesthesiajournal_title
Anaesthesiaauthors
Sear JW,Shaw I,Wolf A,Kay NHdoi
10.1111/j.1365-2044.1988.tb09062.xsubject
Has Abstractpub_date
1988-03-01 00:00:00pages
18-22eissn
0003-2409issn
1365-2044journal_volume
43 Supplpub_type
杂志文章相关文献
ANAESTHESIA文献大全abstract::Oxygen delivery using nasal prongs was assessed using a lung model for spontaneous ventilation. The analogue lung was attached to a manikin, which provided a model of the 'face and pharynx' to which the nasal prongs were applied. Oxygen concentrations were measured in the model trachea at varying fresh gas inflow and ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1992.tb02331.x
更新日期:1992-07-01 00:00:00
abstract::A case is reported of resistance to the muscle relaxing action of suxamethonium due to the rare inherited condition of hypercholinesterasaemia. Family studies suggest dominant inheritance. It is suggested the condition should be considered whenever there is unexpected resistance to the muscle relaxing action of suxame...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1987.tb04110.x
更新日期:1987-08-01 00:00:00
abstract::Claims notified to the NHS Litigation Authority in England between 1995 and 2007 and filed under anaesthesia were analysed to explore patterns of injury and cost related to airway or respiratory events. Of 841 interpretable claims the final dataset contained 96 claims of dental damage, 67 airway-related claims and 24 ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2010.06331.x
更新日期:2010-06-01 00:00:00
abstract::A multicentre trial of the use of the intubating laryngeal mask was carried out at seven centres in the United Kingdom using the same agreed protocol. Lung ventilation followed by blind tracheal intubation through the intubating laryngeal mask was attempted on 500 ASA grade 1 and 2 patients. It was possible to insert ...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1046/j.1365-2044.1998.00614.x
更新日期:1998-12-01 00:00:00
abstract::A double-blind controlled study was performed to assess the efficacy and safety of patient-controlled analgesia in burn patients. This method was compared with conventional analgesic therapy consisting of intermittent intravenous morphine injections. Twenty-four adult patients hospitalised for burn injuries participat...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1992.tb02266.x
更新日期:1992-06-01 00:00:00
abstract::We assessed adequacy of ventilation in 20 critically ill patients with multiple organ failure using a Pneupac Ventipac portable ventilator and the effects on patients' haemodynamic stability. Baseline data were recorded over 15 min for a range of respiratory, haemodynamic and oxygen transport variables during ventilat...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1046/j.1365-2044.2001.02219.x
更新日期:2001-11-01 00:00:00
abstract::The measurement of extravascular lung water is a relatively new technology which has not yet been well validated as a clinically useful tool. We studied its utility in patients undergoing pulmonary endarterectomy as they frequently suffer reperfusion lung injury and associated oedematous lungs. Such patients are there...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/anae.14744
更新日期:2019-10-01 00:00:00
abstract::Postmortem specimens of 10 patients who had received continuous epidural anaesthesia postoperatively (ranging from 2-21 days) were examined. Slight epidural haemorrhage was observed in six patients and a macroscopically visible haematoma in a thrombocytopenic patient. Nonspecific epidural inflammatory reactions were o...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1990.tb14775.x
更新日期:1990-05-01 00:00:00
abstract::The interaction of halothane and pancuronium is demonstrated in the dog tibialis anterior-sciatic nerve preparation. The results show a dose related effect of halothane on the recovery index and the 50% recovery times. These results are compared to other reports and possible mechanisms are discussed. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1978.tb08341.x
更新日期:1978-02-01 00:00:00
abstract::Opioid induced respiratory depression is potentially fatal. The aim of this study was to validate a monitoring system that could be used to assess respiratory depression in postoperative patients. The hypercapnic ventilatory response was estimated non-invasively in 12 volunteers. In two steps, we tested a system which...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2005.04153.x
更新日期:2005-05-01 00:00:00
abstract::The use of intra-operative Doppler oesophageal probes provides continuous monitoring of cardiac output. This enables optimisation of intravascular volume and tissue perfusion in major abdominal surgery, which is thought to reduce postoperative complications and shorten hospital stay. Medline and EMBASE were searched u...
journal_title:Anaesthesia
pub_type: 杂志文章,meta分析,评审
doi:10.1111/j.1365-2044.2007.05233.x
更新日期:2008-01-01 00:00:00
abstract::After carotid endarterectomy under general anaesthesia, the rapid elimination of desflurane and sevoflurane may allow earlier postoperative neurological assessment than after the use of isoflurane. However, desflurane may be associated with tachycardia and hypertension and may therefore increase cardiovascular risk. W...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章
doi:10.1046/j.1365-2044.2000.01617.x
更新日期:2000-11-01 00:00:00
abstract::The management of childbirth, including epidural anaesthesia for Caesarean section is described in a patient with von Hippel-Lindau disease. The reasons for the choice of epidural anaesthesia are explained and the anaesthetic significance of the disease is discussed. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1986.tb13132.x
更新日期:1986-08-01 00:00:00
abstract::A 38-year-old woman developed symptoms of anaphylactic shock after intravenous atropine and required adrenaline to maintain perfusion pressure. A strongly positive response was obtained on intradermal testing. The Prausnitz-Kuestner test was also positive, which indicated the presence of drug specific IgE antibodies. ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1988.tb05661.x
更新日期:1988-11-01 00:00:00
abstract::As COVID-19 disease escalates globally, optimising patient outcome during this catastrophic healthcare crisis is the number one priority. The principles of patient blood management are fundamental strategies to improve patient outcomes and should be given high priority in this crisis situation. The aim of this expert ...
journal_title:Anaesthesia
pub_type: 杂志文章,评审
doi:10.1111/anae.15095
更新日期:2020-08-01 00:00:00
abstract::We compared the pharmacokinetics, pharmacodynamics and safety profile of a new galenic formulation of propofol (AM149 1%), which does not contain soyabean oil, with a standard formulation of propofol (Disoprivan 1%). In a randomised, double-blind, cross-over study, 30 healthy volunteers received a single intravenous b...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1365-2044.2003.03345.x
更新日期:2003-11-01 00:00:00
abstract::A myriad of new intubation equipment has been introduced commercially since the appearance of Macintosh/Miller blades in the 1940s. We review the role of devices that are relevant to current clinical practice based on their presence in the scientific literature. The comparative performance of new vs traditional direct...
journal_title:Anaesthesia
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2044.2011.06935.x
更新日期:2011-12-01 00:00:00
abstract:SUMMARY:In a randomised, double-blinded study, we compared boluses of phenylephrine 100 microg with ephedrine 10 mg for treating hypotension (systolic blood pressure < 100 mmHg) in 204 patients having non-elective Caesarean section under spinal anaesthesia. Umbilical arterial (UA) and venous (UV) pH and base excess wer...
journal_title:Anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1365-2044.2008.05635.x
更新日期:2008-12-01 00:00:00
abstract::The incidence of pneumothorax in the neonatal period is reviewed. Most infants who developed a pneumothorax were undergoing intermittent positive pressure ventilation. The most common underlying pathology associated with pneumothorax was idiopathic respiratory distress syndrome. This was the only condition in which a ...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1983.tb12024.x
更新日期:1983-10-01 00:00:00
abstract::This study investigated whether pretreatment with glycopyrronium can attenuate the hypotension caused by anaesthesia of the elderly with propofol. Twenty elderly patients (77.1 +/- 2.44 years, mean +/- SEM) of ASA physical status 2 or 3 scheduled for elective urological procedures were given glycopyrronium 0 (n = 10) ...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1365-2044.1992.tb02341.x
更新日期:1992-07-01 00:00:00
abstract::Anaesthesia for abdominal surgery in a patient with carcinoid syndrome is reported. Pre-operative symptomatic improvement was obtained using cyproheptadine hydrochloride. Handling of the tumour and liver metastases, during surgery, produced signs of excess serotonin secretion which responded to intravenous methotrimep...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1976.tb11797.x
更新日期:1976-03-01 00:00:00
abstract::Enteral tube feeding is widely used in intensive care units, high dependency units and general wards. In some patients, an adequate intake is not maintained because patients cannot tolerate the tube. Insertion of an enteral feeding tube via a pharyngostomy is simple and potentially more easily tolerated. We describe o...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.2005.04327.x
更新日期:2005-10-01 00:00:00
abstract::Two patients who had undergone emergency tracheal intubation developed signs of aspiration of ingested food. Nasendoscopy demonstrated supraglottic anaesthesia which recovered from the laryngeal margins in towards the vocal cords. It is assumed that this was caused by a neuropraxia of the internal branch of the superi...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1989.tb11230.x
更新日期:1989-03-01 00:00:00
abstract::The effect of neostigmine on neuromuscular function was examined after spontaneous recovery from an atracurium-induced neuromuscular blockade, which reached a train-of-four ratio of either 0.5 or 0.9. Two doses of neostigmine 2.5 mg were given 5 minutes apart. Neuromuscular recovery was assessed with train-of-four and...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1989.tb11280.x
更新日期:1989-04-01 00:00:00
abstract::Guidelines recommend restrictive red blood cell transfusion strategies. We conducted an observational study to examine whether the rate of peri-operative red blood cell transfusion in the USA had declined during the period from 01 January 2011 to 31 December 2016. We included 4,273,168 patients from all surgical subsp...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/anae.14900
更新日期:2020-04-01 00:00:00
abstract::Difficulty in tracheal intubation in paediatric intensive care patients is associated with increased morbidity and mortality. Delays to intubation and interruption to oxygenation and ventilation are poorly tolerated. We developed a safe and atraumatic tracheal intubation technique. A floppy-tipped guidewire and airway...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/anae.14008
更新日期:2017-11-01 00:00:00
abstract::The Combitube airway allows short-term ventilation during cardiopulmonary resuscitation and can be useful in the management of the difficult airway. In a prospective observational study we assessed its use during percutaneous dilatational tracheostomy (PDT). Twenty-one intensive care patients scheduled for elective PD...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章
doi:10.1046/j.1365-2044.1998.00320.x
更新日期:1998-03-01 00:00:00
abstract::An anaesthetic technique is described for laparoscopy using an intravenous induction, atracurium 0.2 mg/kg for muscle relaxation and intermittent positive pressure ventilation of the lungs with nitrous oxide and oxygen. It was found to be a suitable and simple technique. Recovery of spontaneous ventilation was achieve...
journal_title:Anaesthesia
pub_type: 临床试验,杂志文章
doi:10.1111/j.1365-2044.1984.tb07243.x
更新日期:1984-03-01 00:00:00
abstract::Halothane hepatitis is extremely rare in childhood. However, this occurred in an 11-month-old infant, following multiple exposure to halothane. The diagnosis was confirmed by detection of specific antibodies to halothane-sensitised rabbit hepatocytes. The anaesthetic technique for a subsequent procedure with a halotha...
journal_title:Anaesthesia
pub_type: 杂志文章
doi:10.1111/j.1365-2044.1986.tb13053.x
更新日期:1986-06-01 00:00:00
abstract::A long-forgotten chloroform inhaler, probably the first accurately calibrated, temperature compensatable, plenum vaporizer, is described. Its place in the dosimetric movement at the beginning of the 20th century is considered, together with a brief account of the life of its designer. ...
journal_title:Anaesthesia
pub_type: 传,历史文章,杂志文章
doi:10.1111/j.1365-2044.1988.tb05667.x
更新日期:1988-11-01 00:00:00