When the air hits your brain: cerebral autoregulation of brain oxygenation during aerobic exercise allows transient hyperoxygenation: case report.

Abstract:

OBJECTIVE:Cerebral autoregulation maintains a relatively stable cerebral blood flow over a range of perfusion pressures. During exercise, regional cerebral blood flow may be elevated in particular areas of the brain. This case report presents the impact of aerobic exercise on intracranially measured pressure and brain tissue oxygenation in an adult human. CLINCIAL PRESENTATION:A 30-year-old man with idiopathic intracranial hypertension treated with cerebrospinal fluid diversion was monitored with a Licox intracranial brain oxygen and pressure monitor (Integra NeuroSciences Corporation, Plainsboro, New Jersey) for refractory nonpostural headaches exacerbated after exercise. He performed trials of running and bicycling to provoke his headaches. The patient's mean intracranial pressure remained stable during exercise despite elevated cerebral perfusion pressures. Regional cerebral oxygen tension levels were strictly regulated to a level of approximately 39 mm Hg during steady state aerobic exercise, with transient increases up to 90 mm Hg at the onset and termination of activity. CONCLUSION:Our results suggest that cerebral autoregulation appears to maintain constant cerebral oxygen tension during exercise. Further, we note transient cerebral hyperoxygenation at the onset of exercise as autoregulation "turns on" and at the termination of exercise. We present a quantitative interpretation of the post-exercise hyperoxygenation phase based on Fick's principle. We are the first to demonstrate cortical hyperoxygenation in a human breathing natural air without oxygen supplementation.

journal_name

Neurosurgery

journal_title

Neurosurgery

authors

Bollo RJ,Williams SC,Peskin CS,Samadani U

doi

10.1227/01.NEU.0000371976.21043.C8

subject

Has Abstract

pub_date

2010-08-01 00:00:00

pages

E507-9

issue

2

eissn

0148-396X

issn

1524-4040

pii

00006123-201008000-00047

journal_volume

67

pub_type

杂志文章
  • A new, more accurate classification of middle cerebral artery aneurysms: computed tomography angiographic study of 1,009 consecutive cases with 1,309 middle cerebral artery aneurysms.

    abstract:BACKGROUND:Classification of middle cerebral artery (MCA) aneurysms is sometimes difficult because the identification of the main MCA bifurcation, the key for accurate classification of MCA aneurysms, is inconsistent and somewhat subjective. OBJECTIVE:To use the meeting point of the M1 and M2 trunks as an objective, g...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000429842.61213.d5

    authors: Elsharkawy A,Lehečka M,Niemelä M,Billon-Grand R,Lehto H,Kivisaari R,Hernesniemi J

    更新日期:2013-07-01 00:00:00

  • Brachial plexus compression caused by recurrent clavicular nonunion and space-occupying pseudoarthrosis: definitive reconstruction using free vascularized bone flap-a series of eight cases.

    abstract:OBJECTIVE:In rare cases, space-occupying pseudoarthrotic clavicular nonunion causes symptomatic brachial plexus compression. The surgical treatment of clavicular pseudoarthrosis has been extensively reported in the literature. This article reports our experience of a definitive treatment strategy using free vascularize...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000326036.54714.17

    authors: Krishnan KG,Mucha D,Gupta R,Schackert G

    更新日期:2008-05-01 00:00:00

  • Design and Physical Properties of 3-Dimensional Printed Models Used for Neurointervention: A Systematic Review of the Literature.

    abstract:BACKGROUND:Three-dimensional (3D) printing has revolutionized training, education, and device testing. Understanding the design and physical properties of 3D-printed models is important. OBJECTIVE:To systematically review the design, physical properties, accuracy, and experimental outcomes of 3D-printed vascular model...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1093/neuros/nyaa134

    authors: Waqas M,Mokin M,Lim J,Vakharia K,Springer ME,Meess KM,Ducharme RW,Ionita CN,Nagesh SVS,Gutierrez LC,Snyder KV,Davies JM,Levy EI,Siddiqui AH

    更新日期:2020-09-15 00:00:00

  • Surgical decompression without transposition for ulnar neuropathy: factors determining outcome.

    abstract::Fifty-one surgical decompressions without nerve transposition for ulnar neuropathy were performed in 46 patients. All of the patients were men with an average age of 59 years at the time of surgery. The follow-up range was between 5 and 32 months (average, 17.8 months). The disease involved the nondominant arm in 24 p...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199011000-00007

    authors: LeRoux PD,Ensign TD,Burchiel KJ

    更新日期:1990-11-01 00:00:00

  • Depression of circulating blood volume in patients after subarachnoid hemorrhage: implications for the management of symptomatic vasospasm.

    abstract::The result of 42 blood volume determinations made with autologous red blood cells labeled with chromium-51 are reported. The subjects consisted of 11 control patients and 25 patients with recent subarachnoid hemorrhage (SAH). The mean red blood cell volume (RBCV) and the total blood volume (TBV) for female patients af...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198409000-00010

    authors: Solomon RA,Post KD,McMurtry JG 3rd

    更新日期:1984-09-01 00:00:00

  • Effect of intravenous mannitol on cat pial arteries and veins during normal and elevated intracranial pressure.

    abstract::In two series of cats, totaling 12 animals, the effect of 1 g of intravenous mannitol per kg over 15 minutes on pial vessels (cranial window technique, multichannel videoangiometry) and intracranial pressure (ICP) was investigated under circumstances of normal ICP and ICP elevated to 20 mm Hg by the cisternal infusion...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198708000-00002

    authors: Auer LM,Haselsberger K

    更新日期:1987-08-01 00:00:00

  • Normal computed tomograms in acute head injury: correlation of intracranial pressure, ventricular size, and outcome.

    abstract::To assess the predictive value of a normal computed tomographic (CT) scan obtained shortly after head injury, we reviewed all cases of patients with acute closed injury seen at the North Carolina Baptist Hospital over a 42-month period for whom initial CT scanning and continuous intracranial pressure (ICP) monitoring ...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:

    authors: Holliday PO 3rd,Kelly DL Jr,Ball M

    更新日期:1982-01-01 00:00:00

  • Meningioma with intracerebral hematoma.

    abstract::A case of spontaneous intracranial hemorrhage associated with a meningioma is presented. Intracranial hemorrhage has been reported to be associated with meningioma in 45 cases. A comprehensive review of the subject is presented. The importance of the diagnosis of associated hemorrhage and subsequent surgical intervent...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198408000-00014

    authors: Kohli CM,Crouch RL

    更新日期:1984-08-01 00:00:00

  • The effectiveness of interventions to reduce neurological injuries in rugby union: a systematic review.

    abstract:BACKGROUND:Rugby is characterized by high-speed collisions among the players that predispose them to injuries, particularly to the head, neck, and spine. OBJECTIVE:To evaluate the effectiveness of current neurological injury prevention strategies in rugby union. METHODS:Systematic review in May 2010. We assessed the ...

    journal_title:Neurosurgery

    pub_type: 杂志文章,meta分析,评审

    doi:10.1227/NEU.0b013e3181f209f1

    authors: Cusimano MD,Nassiri F,Chang Y

    更新日期:2010-11-01 00:00:00

  • Isolation and perivascular localization of mesenchymal stem cells from mouse brain.

    abstract:BACKGROUND:Although originally isolated from the bone marrow, mesenchymal stem cells (MSCs) have recently been detected in other tissues. However, little is known about MSCs in the brain. OBJECTIVE:To determine the extent to which cells with the features of MSCs exist in normal brain tissue and to determine the locati...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.NEU.0000377859.06219.78

    authors: Kang SG,Shinojima N,Hossain A,Gumin J,Yong RL,Colman H,Marini F,Andreeff M,Lang FF

    更新日期:2010-09-01 00:00:00

  • Spontaneous resolution of chronic epidural hematomas: report of three cases.

    abstract::We report three cases of the spontaneous resolution of a traumatic chronic epidural hematoma. The patients were young adults with only mild headache after trauma. All patients were treated conservatively because of the very mild symptoms and the time lapse of 1 to 2 weeks between trauma and our unexpected detection of...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198407000-00018

    authors: Tochio H,Waga S,Tashiro H,Takeuchi T,Miyazaki M

    更新日期:1984-07-01 00:00:00

  • Cephaloceles: treatment, outcome, and antenatal diagnosis.

    abstract::A series of 74 cephaloceles (17 cranial meningoceles and 57 meningoencephaloceles) is reported. Infants born with large meningoencephaloceles containing recognizable cerebral tissue usually did badly despite endeavors to conserve brain function by expanding the cranial capacity (5 cases) or decompressing hydrocephalic...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198407000-00005

    authors: Simpson DA,David DJ,White J

    更新日期:1984-07-01 00:00:00

  • The Use of Vancomycin Powder for Surgical Prophylaxis Following Craniotomy.

    abstract:BACKGROUND:Intrawound vancomycin powder has been studied extensively in spinal fusion surgeries and been found to reduce rates of surgical site infections (SSIs) significantly. Despite its success in spinal surgeries, topical vancomycin has not been extensively studied with respect to cranial neurosurgery. OBJECTIVE:T...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1093/neuros/nyw127

    authors: Ravikumar V,Ho AL,Pendhakar AV,Sussman ES,Kwong-Hon Chow K,Li G

    更新日期:2017-05-01 00:00:00

  • Refined and simplified surgical landmarks for the MacCarty keyhole and orbitozygomatic craniotomy.

    abstract:BACKGROUND:Precise placement of the MacCarty keyhole, a burr hole simultaneously exposing the anterior cranial fossa floor and orbit, provides accurate, efficient entry for orbitozygomatic and supraorbital craniotomies. To locate the optimal keyhole site, previous studies have used superficial landmarks that, in our ex...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.NEU.0000369650.69583.9C

    authors: Tubbs RS,Loukas M,Shoja MM,Cohen-Gadol AA

    更新日期:2010-06-01 00:00:00

  • Postoperative infection may influence survival in patients with glioblastoma: simply a myth?

    abstract:BACKGROUND:It is a prevalent myth that a postoperative infection may actually confer a survival advantage in patients with malignant glioma. This contention is based largely on anecdotal reports. Recently, a single-center study showed there was no survival advantage in those patients who had glioblastoma with postopera...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0b013e318222adfa

    authors: De Bonis P,Albanese A,Lofrese G,de Waure C,Mangiola A,Pettorini BL,Pompucci A,Balducci M,Fiorentino A,Lauriola L,Anile C,Maira G

    更新日期:2011-10-01 00:00:00

  • Transient syringomyelia leading to acute neurological deterioration after repair of a lipomyelomeningocele: case report.

    abstract:OBJECTIVE:Transient paraplegia in the immediate postoperative period after lipomyelomeningocele repair is uncommon and is not discussed in the literature. We present the unique case of a patient who developed transient paraplegia 48 hours after lipomyelomeningocele repair attributable to the acute development of a thor...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.NEU.0000255523.50203.FC

    authors: Post NH,Wisoff JH,Thorne CH,Weiner HL

    更新日期:2007-08-01 00:00:00

  • The abducted arm as a sign of ruptured cervical disc.

    abstract::A helpful clinical sign of ruptured cervical disc is pain relief upon arm abduction. When the disease process is spondylosis with foraminal stenosis, changing arm position does not relieve pain. Anatomical considerations are discussed. ...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198711000-00024

    authors: Beatty RM,Fowler FD,Hanson EJ Jr

    更新日期:1987-11-01 00:00:00

  • Saccular intracranial aneurysm disease: distribution of site, size, and age suggests different etiologies for aneurysm formation and rupture in 316 familial and 1454 sporadic eastern Finnish patients.

    abstract:OBJECTIVE:Finnish saccular intracranial aneurysm (sIA) disease associates to 2q33, 8q11, and 9p21 loci and links to 19q13, Xp22, and kallikrein cluster in sIA families. Detailed phenotyping of familial and sporadic sIA disease is required for fine mapping of the Finnish sIA disease. METHODS:Eastern Finland, which is p...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.NEU.0000367634.89384.4B

    authors: Huttunen T,von und zu Fraunberg M,Frösen J,Lehecka M,Tromp G,Helin K,Koivisto T,Rinne J,Ronkainen A,Hernesniemi J,Jääskeläinen JE

    更新日期:2010-04-01 00:00:00

  • Significant differences in the postoperative morphological and hemodynamic conditions of carotid arteries of patients undergoing stenting or endarterectomy with patch angioplasty.

    abstract:OBJECTIVE:Carotid endarterectomy with a patch graft (Patch CEA) has been our standard treatment for patients with carotid artery stenosis, but carotid artery stenting (CAS) has emerged as an alternative. The purpose of this study was to compare the postoperative changes in the configurations and the flow velocities of ...

    journal_title:Neurosurgery

    pub_type: 临床试验,杂志文章

    doi:10.1227/01.NEU.0000358952.12917.DF

    authors: Tokunaga K,Sugiu K,Hayase H,Nishida A,Date I

    更新日期:2009-11-01 00:00:00

  • Percutaneous balloon angioplasty for acute occlusion of intracranial arteries.

    abstract:BACKGROUND:The benefits of intravenous thrombolysis for acute ischemic stroke are still limited. OBJECTIVE:To evaluate the safety and efficacy of double-lumen balloon catheter-based reperfusion therapy with or without intra-arterial thrombolysis for acute occlusion of intracranial arteries. METHODS:Fifty-nine patient...

    journal_title:Neurosurgery

    pub_type: 杂志文章,多中心研究

    doi:10.1227/01.NEU.0000380954.29925.CE

    authors: Tokunaga K,Sugiu K,Yoshino K,Terai Y,Imaoka T,Handa A,Hirotsune N,Kusaka N,Date I

    更新日期:2010-09-01 00:00:00

  • Endoscope-assisted supraorbital craniotomy for lesions of the interpeduncular fossa.

    abstract:OBJECTIVE:The supraorbital approach is well accepted for lesions in the anterior fossa, the sellar region, and the anterior circle of Willis. However, the usefulness of this approach has not yet been elucidated for lesions in the interpeduncular fossa. The technique of an endoscope-assisted, ipsi- and contralateral sup...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199901000-00062

    authors: Menovsky T,Grotenhuis JA,de Vries J,Bartels RH

    更新日期:1999-01-01 00:00:00

  • A clinical evaluation of the Camino subdural screw and ventricular monitoring kits.

    abstract::The aim of this study was to compare readings of intracranial pressure from a ventricular catheter with those obtained from a Camino catheter-tipped transducer. The Camino transducer was evaluated in two ways: firstly, when it was inserted by a subdural screw, and secondly, when it was inserted into a ventricular cath...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199003000-00007

    authors: Chambers IR,Mendelow AD,Sinar EJ,Modha P

    更新日期:1990-03-01 00:00:00

  • New head-positioning system for use with computed tomographic scanning.

    abstract::A new head-positioning system has been developed to hold the head firmly during the performance of a computed tomograhic scan and to position the head reproducibly during repeat scans. This can be used to maintain the head in position during long scanning sessions, to relate a lesion to landmarks on scout views, to fo...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198008000-00006

    authors: Kaufman HH,Gildenberg PL

    更新日期:1980-08-01 00:00:00

  • In Memoriam: A Memoir for Our Fallen "Heroes".

    abstract::Even though neurosurgeons exercise these enormous and versatile skills, the COVID-19 pandemic has shaken the fabrics of the global neurosurgical family, jeopardizing human lives, and forcing the entire world to be locked down. We stand on the shoulders of the giants and will not forget their examples and their teachin...

    journal_title:Neurosurgery

    pub_type: 历史文章,杂志文章

    doi:10.1093/neuros/nyaa314

    authors: Chaurasia B,Deora H,El-Ghandour NMF,Oyesiku NM,Chaurasia RK,Schulder M,Soriano Sanchez JA,Teo M,Hernesniemi J,Linzey JR,Schwartz TH,Cohen-Gadol AA,Lawton M,Umana G,Mura J,Grotenhuis A,Sinha AK,Schroeder HWS,Natarajan

    更新日期:2020-09-15 00:00:00

  • False aneurysm complicating carotid endarterectomy.

    abstract::We present two cases of false aneurysm after carotid endarterectomy with primary arteriotomy closure. In both cases, infection appeared to be the precipitating cause. Both lesions were repaired with a saphenous vein patch graft, but infection in one patient persisted, and recurrence of a false aneurysm required ligati...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198609000-00014

    authors: Branch CL Jr,Davis CH Jr

    更新日期:1986-09-01 00:00:00

  • Bypass grafting and revascularization in the management of posterior circulation aneurysms.

    abstract:OBJECTIVE:To describe the bypass techniques, cranial base approaches, results of treatment, causes of failure, and lessons that are learned in patients with posterior circulation aneurysms requiring revascularization. METHODS:Retrospectively, 19 patients with posterior fossa aneurysms requiring revascularization proce...

    journal_title:Neurosurgery

    pub_type: 杂志文章,多中心研究

    doi:10.1227/01.neu.0000140822.64362.c6

    authors: Evans JJ,Sekhar LN,Rak R,Stimac D

    更新日期:2004-11-01 00:00:00

  • The rete mirabile of the cranial base: a millenary legend.

    abstract::The rete mirabile, a vascular network assumed to give origin to the intracranial segments of the internal carotid arteries, was interpreted by Galen as the key station for the conversion of the "vital spirit" into the "animal spirit." According to this interpretation, the rete was determinant either in sustaining the ...

    journal_title:Neurosurgery

    pub_type: 传,历史文章,杂志文章

    doi:10.1227/01.NEU.0000216118.31290.65

    authors: Viale G

    更新日期:2006-06-01 00:00:00

  • Microscope-integrated quantitative analysis of intraoperative indocyanine green fluorescence angiography for blood flow assessment: first experience in 30 patients.

    abstract:BACKGROUND:Intraoperative measurements of cerebral blood flow are of interest during vascular neurosurgery. Near-infrared indocyanine green (ICG) fluorescence angiography was introduced for visualizing vessel patency intraoperatively. However, quantitative information has not been available. OBJECTIVE:To report our ex...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0b013e31822f7d7c

    authors: Kamp MA,Slotty P,Turowski B,Etminan N,Steiger HJ,Hänggi D,Stummer W

    更新日期:2012-03-01 00:00:00

  • Simple method for determining the need for sternotomy/manubriotomy with the anterior approach to the cervicothoracic junction.

    abstract:OBJECTIVE:Frequently, the cervicothoracic junction can be reached through a simple anterior approach. In some cases, access to this region requires a much more aggressive surgical intervention, such as manubriotomy or sternotomy. Information regarding the need for such interventions is particularly useful to have preop...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.NEU.0000347472.07670.EB

    authors: Karikari IO,Powers CJ,Isaacs RE

    更新日期:2009-12-01 00:00:00

  • Simvastatin attenuates microglial cells and astrocyte activation and decreases interleukin-1beta level after traumatic brain injury.

    abstract:OBJECTIVE:Our previous studies demonstrated that simvastatin promotes neurological functional recovery after traumatic brain injury (TBI) in rat; however, the underlying mechanisms remain poorly understood. The purpose of this study was to investigate the anti-inflammatory effect of simvastatin by measuring the level o...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.NEU.0000346272.76537.DC

    authors: Li B,Mahmood A,Lu D,Wu H,Xiong Y,Qu C,Chopp M

    更新日期:2009-07-01 00:00:00