The Use of Vancomycin Powder for Surgical Prophylaxis Following Craniotomy.

Abstract:

BACKGROUND:Intrawound vancomycin powder has been studied extensively in spinal fusion surgeries and been found to reduce rates of surgical site infections (SSIs) significantly. Despite its success in spinal surgeries, topical vancomycin has not been extensively studied with respect to cranial neurosurgery. OBJECTIVE:To evaluate the efficacy of intrawound topical vancomycin for prevention of SSIs following open craniotomies. METHODS:We retrospectively analyzed a large series of 350 patients from 2011 to 2015 in a pre/postintervention study of use of topical vancomycin to reduce postoperative craniotomy infection rates. We had a preintervention control group of 225 patients and a postintervention group of 125 patients that received intrawound topical vancomycin. RESULTS:Our preintervention incidence of SSI was 2.2% and this was significantly reduced to 0% following introduction of topical vancomycin ( P < .5). An ad hoc cost analysis suggested a cost savings of ${\$}$ 59 965 with the use of topical vancomycin for craniotomies. CONCLUSION:Our study found a significant reduction in SSI rates after introduction of topical vancomycin. Thus, this simple intervention should be considered in all open craniotomy patients as both infection prophylaxis and a potential cost saving intervention.

journal_name

Neurosurgery

journal_title

Neurosurgery

authors

Ravikumar V,Ho AL,Pendhakar AV,Sussman ES,Kwong-Hon Chow K,Li G

doi

10.1093/neuros/nyw127

subject

Has Abstract

pub_date

2017-05-01 00:00:00

pages

754-758

issue

5

eissn

0148-396X

issn

1524-4040

pii

2953190

journal_volume

80

pub_type

杂志文章
  • Regulation of hexokinase in cultured gliomas.

    abstract::Positron emission computed tomographic (PECT) scanning studies have demonstrated that high grade gliomas exhibit increased 2-[18F]fluoro-2-deoxyglucose (18FDG) uptake compared to cerebral white matter and low grade gliomas. Hexokinase catalyzes the phosphorylation of glucose, as well as 18FDG and 2-deoxyglucose (2DG),...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198510000-00001

    authors: Graham JF,Cummins CJ,Smith BH,Kornblith PL

    更新日期:1985-10-01 00:00:00

  • The juxtaposition of a capillary telangiectasia, cavernous malformation, and developmental venous anomaly in the brainstem of a single patient: case report.

    abstract:OBJECTIVE AND IMPORTANCE:Capillary telangiectasias, cavernous malformations, and developmental venous anomalies are all vascular malformations that occur on the capillary-venous side of the cerebral circulation. The associations of capillary telangiectasias with venous malformations, cavernous malformations with venous...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-200111000-00044

    authors: Clatterbuck RE,Elmací I,Rigamonti D

    更新日期:2001-11-01 00:00:00

  • External ventricular drainage in the management of posterior fossa tumors in children and adolescents.

    abstract::External ventricular drainage (EVD) was used before and after posterior fossa operations in 62 children and adolescents. In all cases, the removal of the tumor (midline in 47 and laternal in 15) was attempted; total removal was achieved in 41. The overall mortality was 6.5% (4 patients). Only 25% of the survivors need...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:

    authors: Papo I,Caruselli G,Luongo A

    更新日期:1982-01-01 00:00:00

  • History of spine biomechanics: part I--the pre-Greco-Roman, Greco-Roman, and medieval roots of spine biomechanics.

    abstract::The roots of spine biomechanics reside in the Antiquity and the Medieval and Renaissance periods. A review of historical treatises reveals detailed information regarding this often historically neglected discipline. Ancient medical, philosophical, and physical documents were reviewed, as they pertained to the historic...

    journal_title:Neurosurgery

    pub_type: 历史文章,杂志文章

    doi:10.1227/01.NEU.0000249276.94933.8D

    authors: Naderi S,Andalkar N,Benzel EC

    更新日期:2007-02-01 00:00:00

  • Primary Leptomeningeal Gliomatosis in Children and Adults: A Morphological and Molecular Comparative Study With Literature Review.

    abstract:BACKGROUND:Primary leptomeningeal gliomatosis (PLG) is a poorly recognized tumor of the central nervous system. OBJECTIVE:To describe the histopathological, immunohistochemical, and molecular features of PLG. METHODS:Results of our multicentric retrospective study of 6 PLG cases (3 pediatric and 3 adult) were compare...

    journal_title:Neurosurgery

    pub_type: 杂志文章,多中心研究

    doi:10.1227/NEU.0000000000001028

    authors: Tauziede-Espariat A,Maues de Paula A,Pages M,Laquerriere A,Caietta E,Delpont B,Viennet G,Medeiros de Bustos E,Moulin T,Barnerias C,Vauleon E,Grill J,Chiforeanu D,Vasiljevic A,Varlet P

    更新日期:2016-03-01 00:00:00

  • Repeat transsphenoidal surgery for the treatment of remaining or recurring pituitary tumors in acromegaly.

    abstract:BACKGROUND:Acromegaly is a disorder characterized by hypersecretion of growth hormone caused by a growth hormone-secreting pituitary adenoma. OBJECTIVE:To evaluate the long-term efficacy and safety of repeat transsphenoidal surgery for persistent or recurrent acromegaly. METHODS:We retrospectively reviewed records fo...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0b013e3181ec4379

    authors: Yamada S,Fukuhara N,Oyama K,Takeshita A,Takeuchi Y

    更新日期:2010-10-01 00:00:00

  • The multiple tumor suppressor 1/cyclin-dependent kinase inhibitor 2 gene in human central nervous system primitive neuroectodermal tumor.

    abstract::The recently described multiple tumor suppressor 1/cyclin-dependent kinase inhibitor 2 (MTS1/CDKN2) gene, encoding the cyclin-dependent kinase 4 inhibitor p16, is mutated in a wide variety of tumor cell lines, including gliomas. To investigate the possible role of this gene in the genesis of the central nervous system...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-199505000-00013

    authors: Raffel C,Ueki K,Harsh GR 4th,Louis DN

    更新日期:1995-05-01 00:00:00

  • A novel technique of odontoidoplasty and C1 arch reconstruction: anatomical and biomechanical basis.

    abstract:BACKGROUND:Transoral odontoidectomy and resection of the anterior C1 arch destabilize the atlantoaxial joint and risk its stability. OBJECTIVE:To preserve stability in such cases we devised and evaluated a proof-of-concept study. The arch and dens were dissected and decompression was performed on cadavers. The dens wa...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0b013e31820934a9

    authors: Agrawal A,Reyes PM

    更新日期:2011-03-01 00:00:00

  • Inhibitory effects of sodium butyrate on proliferation and invasiveness of human glioma cells.

    abstract:OBJECTIVE:Sodium butyrate (SB), a differentiation-inducing agent, has been demonstrated to inhibit cellular proliferation in a number of human cell lines. Its precise mechanisms remain to be clarified, however. We investigated molecular mechanisms of SB-induced growth suppression as well as the effects of SB on the inv...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-200108000-00031

    authors: Ito N,Sawa H,Nagane M,Noguchi A,Hara M,Saito I

    更新日期:2001-08-01 00:00:00

  • Pathophysiology of nonneoplastic obstruction of the foramen of Monro and progressive unilateral hydrocephalus.

    abstract::Our experience with progressive unilateral hydrocephalus in children and the pathophysiology of nonneoplastic obstruction of the foramen of Monro has been analyzed. The status of the foramen of Monro in either congenital or acquired progressive unilateral hydrocephalus was classified into the following four categories...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198512000-00003

    authors: Oi S,Matsumoto S

    更新日期:1985-12-01 00:00:00

  • Reversible dural arteriovenous malformation-induced venous ischemia as a cause of dementia: treatment by surgical occlusion of draining dural sinus: case report.

    abstract::We report a unique case of thalamic dementia caused by tentorial dural arteriovenous malformation (AVM), which was successfully treated by surgical occlusion of the straight sinus after attempts to occlude the dural AVM by endovascular procedures had failed. The tentorial dural AVM was fed by bilateral posterior menin...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-199512000-00019

    authors: Ito M,Sonokawa T,Mishina H,Sato K

    更新日期:1995-12-01 00:00:00

  • The beaten copper cranium: a correlation between intracranial pressure, cranial radiographs, and computed tomographic scans in children with craniosynostosis.

    abstract:OBJECTIVE:The beaten copper appearance of the cranium, as well as other cranial radiographic and computed tomographic findings in children with craniosynostosis, is often interpreted by clinicians as evidence of elevated intracranial pressure (ICP). However, a correlation between radiological findings and ICP measureme...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199610000-00007

    authors: Tuite GF,Evanson J,Chong WK,Thompson DN,Harkness WF,Jones BM,Hayward RD

    更新日期:1996-10-01 00:00:00

  • Comparison of the brain tissue response in rats to injury by argon and carbon dioxide lasers.

    abstract::This study compares the acute and chronic response of brain tissue to injury by equal power density, focused argon (Ar) and carbon dioxide (CO2) laser beams. A cortical incision from 0.2-second laser pulses of 12.5 X 10(3) W/cm2 power density was made in the exposed cortex of 32 rats using either the CO2 or the Ar las...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198211000-00004

    authors: Boggan JE,Edwards MS,Davis RL,Bolger CA,Martin N

    更新日期:1982-11-01 00:00:00

  • Techniques for the ventral correction of postsurgical cervical kyphotic deformity.

    abstract::Progressive kyphotic deformity of the cervical spine may be a late sequela of congenital cervical anomalies, degenerative disc disease, neoplasm, cervical trauma, and surgical procedures. Of these, postsurgical kyphosis is the most common and can occur after ventral and dorsal surgeries of the cervical spine. The purp...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000144496.36844.7b

    authors: Stewart TJ,Steinmetz MP,Benzel EC

    更新日期:2005-01-01 00:00:00

  • On the report of the first successful surgical treatment of brain abscess in the Ottoman Empire by Dr. Cemil Topuzlu in 1891.

    abstract::IN 1891, Dr. Cemil Topuzlu operated on a brain abscess that originated as a complication of a depression fracture of the cranial inner table. The patient presented with Jacksonian seizures on his left side after a sharp trauma resulting in a 15 cm-long scalp laceration and underlying linear cranial fracture in the rig...

    journal_title:Neurosurgery

    pub_type: 传,历史文章,杂志文章

    doi:10.1227/01.NEU.0000298917.17001.88

    authors: Mut M,Dinç G,Naderi S

    更新日期:2007-10-01 00:00:00

  • Experimental and clinical studies of eicosanoids in cerebrospinal fluid after spinal cord injury.

    abstract:OBJECTIVE:In an attempt to elucidate a possible role for eicosanoids in the pathogenesis of spinal cord injury (SCI), we measured the concentration of leukotriene (LT) C4, thromboxane B2, and 6-keto-prostaglandin F1 alpha in cerebrospinal fluid in both a canine experimental model and 11 patients with SCIs. METHODS:The...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199611000-00014

    authors: Nishisho T,Tonai T,Tamura Y,Ikata T

    更新日期:1996-11-01 00:00:00

  • Surgical Outcomes for Minimally Invasive vs Open Transforaminal Lumbar Interbody Fusion: An Updated Systematic Review and Meta-analysis.

    abstract:BACKGROUND:Minimally invasive transforaminal lumbar interbody fusion (TLIF)-or MI-TLIF-has been increasing in prevalence compared with open TLIF (O-TLIF) procedures. The use of MI-TLIF is an evolving technique with conflicting reports in the literature about outcomes. OBJECTIVE:To investigate the impact of MI-TLIF in ...

    journal_title:Neurosurgery

    pub_type: 杂志文章,meta分析,评审

    doi:10.1227/NEU.0000000000000913

    authors: Khan NR,Clark AJ,Lee SL,Venable GT,Rossi NB,Foley KT

    更新日期:2015-12-01 00:00:00

  • Guidelines for the Management of Severe Traumatic Brain Injury, Fourth Edition.

    abstract::The scope and purpose of this work is 2-fold: to synthesize the available evidence and to translate it into recommendations. This document provides recommendations only when there is evidence to support them. As such, they do not constitute a complete protocol for clinical use. Our intention is that these recommendati...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0000000000001432

    authors: Carney N,Totten AM,O'Reilly C,Ullman JS,Hawryluk GW,Bell MJ,Bratton SL,Chesnut R,Harris OA,Kissoon N,Rubiano AM,Shutter L,Tasker RC,Vavilala MS,Wilberger J,Wright DW,Ghajar J

    更新日期:2017-01-01 00:00:00

  • Clinical evaluation of a depth electroencephalography electrode.

    abstract::Stereo depth electroencephalography (EEG) is of proven benefit in lateralizing and localizing seizure origin in select cases of epilepsy. There are potential hazards and technical considerations inherent with depth EEG, however, that have limited the general applicability of this technique. A new depth EEG electrode w...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198305000-00015

    authors: Maxwell RE,Gates JR,Fiol ME,Johnson MJ,Yap JC,Leppik IE,Gumnit RJ

    更新日期:1983-05-01 00:00:00

  • Clinical problem-solving: brachial plexus closed injury and reconstruction.

    abstract:OBJECTIVE:Current management of severe brachial plexus injury has undergone recent modifications, and surgical options have expanded. METHODS:The case of a man with a severe closed brachial plexus injury resulting from a motorcycle accident is presented. The patient is found to have upper root avulsions that deprive h...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.neu.0000333305.57060.00

    authors: Ranalli NJ,Kline DG,McGarvey ML,Boulis NM,Zager EL

    更新日期:2008-06-01 00:00:00

  • Stent-assisted coiling of wide-necked aneurysms in the setting of acute subarachnoid hemorrhage: experience in 65 patients.

    abstract:BACKGROUND:Stent-assisted coiling in the setting of subarachnoid hemorrhage remains controversial. Currently, there is a paucity of data regarding the utility of this procedure and the risks of hemorrhagic and ischemic complications. OBJECTIVE:To assess the utility of stent-assisted coil embolization and pretreatment ...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0b013e318246a4b1

    authors: Amenta PS,Dalyai RT,Kung D,Toporowski A,Chandela S,Hasan D,Gonzalez LF,Dumont AS,Tjoumakaris SI,Rosenwasser RH,Maltenfort MG,Jabbour PM

    更新日期:2012-06-01 00:00:00

  • Surgical approaches to the cavernous sinus: a microsurgical study.

    abstract::The surgical approaches to the cavernous sinus were examined in 50 adult cadaveric cavernous sinuses using magnification of X3 to X40. The following approaches were examined: 1) the superior intradural approach directed through a frontotemporal craniotomy and the roof of the cavernous sinus; 2) the superior intradural...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1097/00006123-199006000-00001

    authors: Inoue T,Rhoton AL Jr,Theele D,Barry ME

    更新日期:1990-06-01 00:00:00

  • Effects of aortic occlusion on regional spinal cord blood flow and somatosensory evoked potentials in sheep.

    abstract::Somatosensory evoked potentials (SEPs) were recorded continuously during aortic occlusion in sheep, with simultaneous measurement of spinal cord blood flow (SCBF) by radiolabeled microspheres. Aortic occlusion was associated with disappearance of the SEPs in seven of nine sheep in 7.8 +/- 4.1 (SD) minutes. SCBF at the...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198711000-00012

    authors: Kaplan BJ,Friedman WA,Gravenstein N,Richards R,Davis RF

    更新日期:1987-11-01 00:00:00

  • Decision making process: problem-based decision making.

    abstract::Clinical problems are often complex. Problems of great complexity are usually associated with a commensurately greater degree of difficulty with respect to the decision making process. This is most certainly true regarding the management of cervical spondylosis. Usually, clinicians make clinically appropriate decision...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/01.NEU.0000249279.79686.E3

    authors: Shedid D,Benzel EC

    更新日期:2007-01-01 00:00:00

  • Surgical view of the lumbar arteries and their branches: an anatomical study.

    abstract:BACKGROUND:Although injury to the lumbar arteries during anterior spinal approaches is often encountered, there are few published articles regarding the relationship between the lumbar arteries and spinal cord ischemia. OBJECTIVE:To examine the morphology of the lumbar arteries and to emphasize their clinical importan...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/NEU.0b013e318205e307

    authors: Arslan M,Comert A,Acar HI,Ozdemir M,Elhan A,Tekdemir I,Tubbs RS,Ugur HC

    更新日期:2011-03-01 00:00:00

  • Spine patient outcomes research trial: do outcomes vary across centers for surgery for lumbar disc herniation?

    abstract:BACKGROUND:Lumbar discectomy is the most commonly performed spine procedure. Academic spine centers with potentially differing caseloads and experience may have different outcomes. OBJECTIVE:To determine whether the choice of center in which surgery is performed affects lumbar discectomy outcomes. METHODS:Spine Patie...

    journal_title:Neurosurgery

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1227/NEU.0b013e31826772cb

    authors: Desai A,Bekelis K,Ball PA,Lurie J,Mirza SK,Tosteson TD,Zhao W,Weinstein JN

    更新日期:2012-10-01 00:00:00

  • Cystic glioma of the brain stem with prolonged survival.

    abstract::An unusual case of benign stem glioma with a 15-year survival is presented. In spite of 12 years of clinical quiescence, a focus of the tumor in the upper brain stem was found at necropsy. Morphologically, the tumor was a cystic pilocytic astrocytoma. The few previously reported similar cases in the same location were...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-198204000-00015

    authors: Soffer D,Sahar A

    更新日期:1982-04-01 00:00:00

  • Hemodynamic evaluation of basilar and vertebral artery angioplasty.

    abstract:OBJECTIVE:The postangioplasty evaluation of a stenotic vessel is often conducted by studying serial angiograms to determine the anatomic reduction in stenosis. In flow-limiting stenosis, the hemodynamic change that accompanies these anatomic changes is of great importance in evaluating the success of the angioplasty. T...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:

    authors: Guppy KH,Charbel FT,Corsten LA,Zhao M,Debrun G

    更新日期:2002-08-01 00:00:00

  • Status of the legal definition of death.

    abstract::A review of the existing models of legislation and state statutes pertaining to the definition of death is presented. Twenty-four states have statutory provision for brain death. Concern still exists about the need for and the form of statutory definitions. Medical criteria are not considered in detail, but the propos...

    journal_title:Neurosurgery

    pub_type: 杂志文章

    doi:10.1227/00006123-197910000-00026

    authors: Selby R,Selby MT

    更新日期:1979-10-01 00:00:00

  • Stereotactic volumetric resection of thalamic pilocytic astrocytomas.

    abstract:OBJECTIVE:To describe the surgical approaches, the radiographic and clinical outcomes, and the long-term follow-up of patients harboring thalamic pilocytic astrocytomas after radical resection by means of a stereotactic volumetric technique. METHODS:Seventy-two patients with thalamic pilocytic astrocytomas underwent s...

    journal_title:Neurosurgery

    pub_type: 临床试验,杂志文章

    doi:10.1227/01.neu.0000279725.13521.a3

    authors: Moshel YA,Link MJ,Kelly PJ

    更新日期:2007-07-01 00:00:00