Intensification of ciliary motility by extracellular ATP.

Abstract:

:Ciliary metachronism and motility were examined optically in tissue cultures from frog palate epithelium as a function of extracellular ATP concentration in the range of 10(-7)-10(-3) M. The main findings were: a) upon addition of ATP the metachronal wavelength increased by a factor of up to 2. b) the velocity of the metachronal wave increased by a factor of up to 5. c) the frequency of ciliary beating increased by a factor of up to 2-3, the increase being temperature insensitive in the range of 15 degrees C-25 degrees C. d) the area under the 1-second FFT spectrum decreased by a factor of up to 2.5. e) the energy of the metachronal wave is increased by a factor of up to 9.5. f) all the spectrum parameters are subject to influence by ATP, as also by ADP and AMP. However, there are pronounced differences in the various responses to them. Based on these findings, physical aspects of the rate increase of particle transport caused by addition of extracellular ATP are explained. A plausible overall chemical mechanism causing pronounced changes in ciliary motility is discussed.

journal_name

Biorheology

journal_title

Biorheology

authors

Ovadyahu D,Eshel D,Priel Z

doi

10.3233/bir-1988-25309

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

489-501

issue

3

eissn

0006-355X

issn

1878-5034

journal_volume

25

pub_type

杂志文章
  • Stress relaxation in cherry fruit.

    abstract::Stress relaxation in three varieties of cherries was studied using the penetration test with a cylindrical pin, 4 mm in diameter, having a flat tip. One half of the fruit was modified by partial skinning, since experiments show that skin approximately doubles the apparent modulus of elasticity of the cherries. The ski...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.1016/s0006-355x(97)00033-4

    authors: Blahovec J

    更新日期:1996-11-01 00:00:00

  • An inflammation-responsive transcription factor in the pathophysiology of osteoarthritis.

    abstract::A number of risk factors including biomechanical stress on the articular cartilage imposed by joint overloading due to obesity, repetitive damage of the joint tissues by injury of the menisci and ligaments, and abnormal joint alignment play a significant role in the onset of osteoarthritis (OA). Genetic predisposition...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:

    authors: Ray A,Ray BK

    更新日期:2008-01-01 00:00:00

  • Viscosity and order in erythrocyte membranes studied with nanosecond fluorometry.

    abstract::The viscosity and the order in the interior of human erythrocyte membranes were investigated by the fluorescence depolarization technique in the nanosecond region with 1,6-diphenyl-1,3,5-hexatriene (DPH). After pulsed excitation with a polarized light, the fluorescence anisotropy ratio of DPH in membranes rapidly decr...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1986-23504

    authors: Araiso T,Shindo Y,Arai T,Nitta J,Kikuchi Y,Kakiuchi Y,Koyama T

    更新日期:1986-01-01 00:00:00

  • Required test duration for group comparisons in ligament viscoelasticity: a statistical approach.

    abstract::The goal of this study was to determine the duration of time that ligaments from a study group need to be loaded in order to adequately determine their collective viscoelastic behavior. Rat ligaments were subjected either to creep or stress relaxation for 1,000 s or stress relaxation for 10,000 s to compare estimates ...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:

    authors: Manley E Jr,Provenzano PP,Heisey D,Lakes R,Vanderby R Jr

    更新日期:2003-01-01 00:00:00

  • Study of red cell aggregation in pulsatile flow from ultrasonic Doppler power measurements.

    abstract::Human red cell aggregability and disaggregability represent important hemorheological parameters of blood. Several techniques have been proposed to evaluate the tendency of red cells to form aggregates and to disrupt in the presence of shear stress. One of the most recent approaches is based on the characterization of...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1993-305-615

    authors: Cloutier G,Shung KK

    更新日期:1993-09-01 00:00:00

  • Pulse shape analysis of RBC micropore flow via new software for the cell transit analyser (CTA).

    abstract::The Cell Transit Analyser (CTA) provides a means to rapidly measure the deformability of large numbers of individual cells. It combines many of the advantages of micropipette studies with the simplicity and speed of filtrometry methods by measuring the duration of each resistive pulse generated as a cell passes throug...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1992-292-301

    authors: Fisher TC,Wenby RB,Meiselman HJ

    更新日期:1992-03-01 00:00:00

  • Effects of diacerein on biosynthesis activities of chondrocytes in culture.

    abstract::The maintenance of articular cartilage integrity requires a balance between anabolic and catabolic processes which are under the control of chondrocytes. These cells are living in an anaerobic environment and normally do not divide. They are responsible for the continuous maintenance of the cartilage extracellular mat...

    journal_title:Biorheology

    pub_type: 杂志文章,评审

    doi:

    authors: Pujol JP,Felisaz N,Boumediene K,Ghayor C,Herrouin JF,Bogdanowicz P,Galera P

    更新日期:2000-01-01 00:00:00

  • Experimental assessment of wall shear flow in models.

    abstract::The blood flow immediately adjacent to the wall of a blood vessel or an artificial surface is of great interest. This flow defines the shear stress at the wall and is known to have a great physiological importance. The use of models is a viable method to investigate this flow. However, even in models the shear stress ...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:

    authors: Affeld K,Kertzscher U,Goubergrits L

    更新日期:2002-01-01 00:00:00

  • Size determination of red blood cell aggregates induced by dextran using ultrasound backscattering phenomenon.

    abstract::Different methods are commonly used to study the red blood cell aggregation phenomenon. The major interest of the ultrasonic method presently discussed is to assess the mean size of red blood cell (RBC) aggregates by measuring ultrasonic intensity backscattered by blood. Applying Rayleigh theory of sound to blood medi...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1990-27104

    authors: Boynard M,Lelievre JC

    更新日期:1990-01-01 00:00:00

  • Flow-dependent concentration polarization of plasma proteins at the luminal surface of a cultured endothelial cell monolayer.

    abstract::Flow-dependent concentration or depletion of atherogenic low density lipoproteins which has been theoretically predicted to occur at a blood/endothelium boundary may play an important role in the genesis, progression, and regression of atherosclerosis in man and intimal hyperplasia in vascular grafts implanted in the ...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:

    authors: Naiki T,Sugiyama H,Tashiro R,Karino T

    更新日期:1999-01-01 00:00:00

  • Structure of blood flow through a curved vessel with an aneurysm.

    abstract::A fine structure of blood flow through a curved vessel with an aneurysm was studied in in vitro experiments in relation to rheological factors of arterial diseases such as arteriosclerosis or thrombosis. On the basis of the in vivo data related to cerebral circulation, red blood cell suspension was flowed through curv...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1984-21418

    authors: Niimi H,Kawano Y,Sugiyama I

    更新日期:1984-01-01 00:00:00

  • Fibrin elasticity and coagulation.

    abstract::Sudden increase of viscosity in former times indicated the start of coagulation. Yet its measurement destroyed the structure of coagulum. By the precursor method of thrombelastography the author 1944 found elasticity to be the essential physiological property of coagulum. In the production of elastic fibrin structure ...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1988-251-221

    authors: Hartert H

    更新日期:1988-01-01 00:00:00

  • The influence of L-sorbose on red cell flow properties, shape and packing ability.

    abstract::Since the sweet ketohexose L-sorbose causes overt hemolysis in dogs but not in man, we examined the possibility that L-sorbose induces a "prehemolytic state" of human red cells, manifesting itself as impairment of rheological red cell properties. After 2 hours incubation at 37 degrees C relative viscosity of red cell ...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1985-22302

    authors: Stäubli M,Wälchli P,Straub PW

    更新日期:1985-01-01 00:00:00

  • Assessment of oxidant susceptibility of red blood cells in various species based on cell deformability.

    abstract::The present study was designed to investigate the oxidant susceptibility of red blood cells (RBC) from four species (echidna, human, koala, Tasmanian devil) based on changes in cellular deformability. These species were specifically chosen based on differences in lifestyle and/or biology associated with varied levels ...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/BIR-2012-0599

    authors: Simmonds MJ,Meiselman HJ,Marshall-Gradisnik SM,Pyne M,Kakanis M,Keane J,Brenu E,Christy R,Baskurt OK

    更新日期:2011-01-01 00:00:00

  • Molecular basis of red cell membrane rheology. Part 1.

    abstract::The biorheological properties and behavior of red blood cells (RBCs), as other types of cells, have a biochemical and molecular basis. The shape maintenance and deformability of RBCs depend on the structural and functional integrity of the membrane proteins. These proteins are composed of transmembrane proteins insert...

    journal_title:Biorheology

    pub_type: 杂志文章,评审

    doi:10.3233/bir-1990-273-410

    authors: Chien S,Sung LP

    更新日期:1990-01-01 00:00:00

  • Influence of parenteral nutrition on blood rheology and platelet aggregation in vitro.

    abstract:BACKGROUND:Parenteral nutrition (PN) is a hyperosmolar solution composed of glucose, amino acids and a lipid emulsion, which is often used despite well-known side effects and complications. OBJECTIVES:In this study the hypothesis was tested that PN could affect hemorheology. METHODS:The influence of increasing plasma...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/BIR-140652

    authors: Compagnoni SC,Schulzki T,Thoeny S,Reinhart WH

    更新日期:2014-01-01 00:00:00

  • Plasma fractionation by dead-end membrane filtration: effects of membrane properties and plasma flux.

    abstract::Plasma fractionation by membrane filtration permits the reinfusion of the patient with his own albumin. In this study, the influence of membrane nature and plasma flux on plasma fractionation in dead-end mode is investigated with acetate hollow fiber filters. It is found that transmembrane pressure TMP rises exponenti...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1991-281-204

    authors: Charcosset C,Ding LH,Jaffrin MY

    更新日期:1991-01-01 00:00:00

  • A structural mathematical model for the viscoelastic anisotropic behaviour of trabecular bone.

    abstract::The presented paper is based on the conclusions of the preceding paper (1). On the basis of a general theoretical approach to the mechanics of heterogeneous materials published earlier / (2) , (3) , (4) / macroscopic constitutive equation of trabecular bone is deduced from the description of its microstructure. For th...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1983-20607

    authors: Kafka V,Jírová J

    更新日期:1983-01-01 00:00:00

  • Osteoarthritic synovial fluid rheology and correlations with protein concentration.

    abstract:BACKGROUND:Osteoarthritis is a common, localized joint disease that causes pain, stiffness and reduced mobility. Osteoarthritis is particularly common in the knees. The effects of osteoarthritis on the rheology of synovial fluid in the knees are not fully understood and consequently require further study. OBJECTIVE:Th...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/BIR-15078

    authors: Madkhali A,Chernos M,Grecov D,Kwok E

    更新日期:2016-11-09 00:00:00

  • Fibrin gels as biological filters and interfaces.

    abstract::We present data which show that fibrin gels are ordered network structures, the porosity of which is determined by the amount of thrombin being present during the activation step preceding gelation. On activation of fibrinogen, fibrinopeptides are released and simultaneously polymers are formed, obeying apparent first...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1984-211-214

    authors: Blombäck B,Okada M,Forslind B,Larsson U

    更新日期:1984-01-01 00:00:00

  • An LDA and flow visualization study of pulsatile flow in an aortic bifurcation model.

    abstract::The structure of pulsatile flow in a rigid aortic bifurcation model was studied by means of a flow visualization technique and three-dimensional laser-Doppler anemometry. The model was made of glass, having the same shape as that of the average human aortic bifurcation. It was installed into a mock circulatory loop th...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1995-32104

    authors: Naiki T,Hayashi K,Takemura S

    更新日期:1995-01-01 00:00:00

  • Ultrasound stimulates proteoglycan synthesis in bovine primary chondrocytes.

    abstract::Mechanical forces can stimulate the production of extracellular matrix molecules. We tested the efficacy of ultrasound to increase proteoglycan synthesis in bovine primary chondrocytes. The ultrasound-induced temperature rise was measured and its contribution to the synthesis was investigated using bare heat stimulus....

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:

    authors: Kopakkala-Tani M,Leskinen JJ,Karjalainen HM,Karjalainen T,Hynynen K,Töyräs J,Jurvelin JS,Lammi MJ

    更新日期:2006-01-01 00:00:00

  • Contactless cell trapping by the use of a uniform AC electric field.

    abstract::The AC electric field-driven manipulation of suspended polarizable particles has become a major technique in micro- and nano-devices. In the present study, suspensions of cultured HeLa cells in isotonic solution were used to explore the mechanisms underlying the suspension behaviors during exposure to a uniform AC ele...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/BIR-130644

    authors: Tada S,Natsuya T,Tsukamoto A,Santo Y

    更新日期:2013-01-01 00:00:00

  • NMDA receptor expression and roles in human articular chondrocyte mechanotransduction.

    abstract::Mechanical forces influence articular cartilage structure by regulating chondrocyte activity. Mechanical stimulation results in activation of an alpha5beta1 integrin dependent intracellular signal cascade involving focal adhesion kinase and protein kinase C, triggering the release of interleukin-4 from the cell. In no...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:

    authors: Salter DM,Wright MO,Millward-Sadler SJ

    更新日期:2004-01-01 00:00:00

  • Effects of vessel size, cell sedimentation and haematocrit on the adhesion of leukocytes and platelets from flowing blood.

    abstract:BACKGROUND:Leukocytes and platelets typically fulfil their functions through adhesion to the walls of vessels with different size, haematocrit and shear rate. OBJECTIVE:We aimed to investigate differential effects of these variables on leukocyte and platelet adhesion. METHODS:Blood with varying haematocrit was perfus...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/BIR-15043

    authors: Watts T,Barigou M,Nash GB

    更新日期:2015-01-01 00:00:00

  • Evaluation of human MSCs cell cycle, viability and differentiation in micromass culture.

    abstract::Mesenchymal stem cells (MSCs) have the potential to differentiate into distinct mesenchymal tissue cells. They are easy to expand while maintaining their undifferentiated state, which suggests that these cells could be an attractive cell source for tissue engineering of cartilage. In vitro high density micromass cultu...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:

    authors: Yang JW,de Isla N,Huselstein C,Sarda-Kolopp MN,Li N,Li YP,Jing-Ping OY,Stoltz JF,Eljaafari A

    更新日期:2006-01-01 00:00:00

  • Time-dependent rheological behaviour of blood flow at low shear in narrow horizontal tubes.

    abstract::Magnitude and time-dependence of the effects of red cell aggregation and sedimentation on the rheology of human blood were studied during low shear (tau W 2.5 to 92 mPa) flow through horizontal tubes (ID 25 to 105 microns). Immediately following reduction of perfusion pressure to a low value the red cell concentration...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1989-26210

    authors: Alonso C,Pries AR,Gaehtgens P

    更新日期:1989-01-01 00:00:00

  • A theoretical analysis of the effects of varying fibrinogen concentration and haematocrit on the flow characteristics of blood in cylindrical tubes.

    abstract::The viscosity: shear rate relationship of whole blood is shown to be described to a good approximation by a bi-linear plot on log: log axes. This has allowed an analytical solution to be obtained which gives a full description of the flow properties of blood in rigid tubes of a size where the Fahraeus-Lindqvist effect...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1983-20204

    authors: Rampling MW,Challoner T

    更新日期:1983-01-01 00:00:00

  • Alteration of red cell membrane viscoelasticity by heat treatment: effect on cell deformability and suspension viscosity.

    abstract::The membrane shear elastic modulus (mu) and the time constant for extensional shape recovery (tc) were measured for normal, control human red blood cells (RBC) and for RBC heat treated (HT) at 48 degrees C. Three separate methods for the measurement of mu were compared (two used a micropipette and one employed a flow ...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.3233/bir-1985-22106

    authors: Nash GB,Meiselman HJ

    更新日期:1985-01-01 00:00:00

  • Measurement of oscillatory flow pressure gradient in an elastic artery model.

    abstract::In vitro experiments were conducted to measure the oscillatory flow pressure gradient along an elastic tube in order to assess the recent nonlinear theory of Wang and Tarbell. According to this theory, in an elastic tube with oscillatory flow, the mean (time-averaged) pressure gradient cannot be calculated using Poise...

    journal_title:Biorheology

    pub_type: 杂志文章

    doi:10.1016/0006-355X(95)00023-3

    authors: Cohen MI,Wang DM,Tarbell JM

    更新日期:1995-07-01 00:00:00