Abstract:
BACKGROUND/OBJECTIVES:Examining handgrip strength (HGS) asymmetry and weakness together may extend the predictive capacity of HGS for capturing possible health problems such as cognitive impairment. The purpose of this study was to determine the associations of HGS asymmetry and weakness on lower cognitive functioning in a national sample of aging Americans. DESIGN:Longitudinal panel. SETTING:Participant residences. PARTICIPANTS:The analytic sample included 17,163 Americans aged 65.0 years (standard deviation = 10.1 years) who participated in the 2006 to 2016 waves of the Health and Retirement Study (HRS). MEASUREMENTS:A handgrip dynamometer was used to measure HGS; weakness was defined as HGS below 26 kg (men) or below 16 kg (women). Persons with HGS above 10% stronger on either hand were considered as having any HGS asymmetry. Those with HGS that was more than 10% stronger on their dominant or nondominant hand were considered as having dominant or nondominant HGS asymmetry, respectively. The Telephone Interview of Cognitive Status determined lower cognitive functioning (≤11 for ages 50-64 years; ≤10 for ages ≥65 years). Covariate-adjusted linear mixed-effects models analyzed the associations of each HGS asymmetry and weakness group on lower cognitive functioning. RESULTS:Relative to those with symmetric HGS and no weakness, each HGS asymmetry and weakness group had greater odds for lower cognitive functioning: 1.15 (95% confidence interval [CI] = 1.03-1.27) for any HGS asymmetry alone, 1.64 (95% CI = 1.21-2.23) for weakness alone, and 1.95 (95% CI = 1.51-2.53) for any HGS asymmetry and weakness. Each HGS asymmetry dominance and weakness group also had greater odds for lower cognitive functioning: 1.12 (95% CI = 1.01-1.25) for asymmetric dominant HGS alone, 1.27 (95% CI = 1.05-1.53) for asymmetric nondominant HGS alone, 1.64 (95% CI = 1.21-2.23) for weakness alone, 1.89 (95% CI = 1.39-2.57) for weakness and asymmetric dominant HGS, and 2.10 (95% CI = 1.37-3.20) for weakness and asymmetric nondominant HGS. CONCLUSION:The presence of both HGS asymmetry and weakness may predict accelerated declines in cognitive functioning.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
McGrath R,Cawthon PM,Cesari M,Al Snih S,Clark BCdoi
10.1111/jgs.16556subject
Has Abstractpub_date
2020-09-01 00:00:00pages
2051-2058issue
9eissn
0002-8614issn
1532-5415journal_volume
68pub_type
杂志文章abstract:OBJECTIVE:To compare the diagnoses, psychiatric and medical comorbidities, and prior and current treatment received by late-middle-aged and older affective disorder patients in mental health and medical service settings and to identify predictors of these patients' length of inpatient care. DESIGN:Department of Vetera...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1996.tb01832.x
更新日期:1996-06-01 00:00:00
abstract::The US Department of Health and Human Services and the Foundation for the National Institutes of Health, through private sector support, sponsored the National Research Summit on Dementia Care: Building Evidence for Services and Supports (Summit) in 2017. Various workgroups were asked to address topics of interest in ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16341
更新日期:2020-03-01 00:00:00
abstract::Measurements were made of the overnight mobility of a group of elderly hospital patients whose clinical status had been assessed using the Norton clinical assessment score. The number of movements on the first two nights after admission differed from subsequent nights. There was a significant correlation between mobil...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1986.tb04903.x
更新日期:1986-09-01 00:00:00
abstract::One hundred seventy-one patients, 60 years of age or older with isolated systolic hypertension, were randomly assigned to receive chlorthalidone 12.5, 25.0, or 50.0 mg or placebo once daily for 12 weeks. The majority of the patients receiving chlorthalidone 12.5 mg achieved therapeutic success with no clinically signi...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1532-5415.1986.tb04203.x
更新日期:1986-03-01 00:00:00
abstract:OBJECTIVES:To determine whether increasing kyphosis angle was independently associated with poorer mobility as measured according to the Timed Up and Go Test (TUG), after controlling for other established risk factors. DESIGN:Prospective cohort study. SETTING:Eleven clinical centers in the United States. PARTICIPANT...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1532-5415.2010.03214.x
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVES:To estimate infection prevalence and explore associated risk factors in nursing home (NH) residents, individuals receiving home health care (HHC), and individuals receiving hospice care. DESIGN:Cross-sectional. SETTING:Nationally representative samples of 1,174 U.S. NHs in the 2004 National Nursing Home Su...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/jgs.12153
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVES:To identify differences in cognitive function between elderly adults with sleep apnea syndrome (SAS) and healthy controls. DESIGN:Cross-sectional. SETTING:Sleep laboratory at Seoul National University Bundang Hospital. PARTICIPANTS:Sixty-three elderly adults (26 female; mean age 68.2 ± 4.8) without cognit...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2012.03961.x
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVES:To investigate the effects of dehydroepiandrosterone (DHEA) combined with exercise on bone mass, strength, and physical function in older, frail women. DESIGN:Double-blind, randomized, placebo-controlled trial. SETTING:A major medical institution. PARTICIPANTS:Ninety-nine women (mean age 76.6 ± 6.0) with ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1532-5415.2010.03019.x
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of Simulated Presence, a personalized approach to enhance well-being among nursing home residents with Alzheimer's disease and related dementia's (ADRD). DESIGN:Latin-Square, double blinded, 3-factor design with restrictive randomization of three treatments (the study intervention, a...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1532-5415.1999.tb07237.x
更新日期:1999-04-01 00:00:00
abstract:OBJECTIVES:To cross-sectionally quantify the contribution of proxy measures of cognitive reserve reflective of the lifespan, such as education, socioeconomic status (SES), reading ability, and cognitive activities, in explaining late-life cognition. DESIGN:Prospective observational cohort study of aging. SETTING:Reti...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2011.03499.x
更新日期:2011-08-01 00:00:00
abstract::Given the American Geriatrics Society's (AGS) commitment to improving health care for older adults by, among other means, educating older people and their caregivers about their health and healthcare choices, the AGS was delighted when, in late 2011, the American Board of Internal Medicine Foundation invited the Socie...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.12226
更新日期:2013-04-01 00:00:00
abstract::The reported prevalence of depressive symptomatology among the elderly ranges from 5 to 65 percent in hospital and community populations. Depression is considered the most common emotional disorder of advanced age. One of the chief diagnostic problems has been the lack of differentiation between disorders manifested b...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1980.tb00205.x
更新日期:1980-02-01 00:00:00
abstract:OBJECTIVES:To test the hypothesis that sleep disturbances are independently associated with frailty status in older men. DESIGN:Cross-sectional analysis of prospective cohort study. SETTING:Six U.S. centers. PARTICIPANTS:Three thousand one hundred thirty-three men aged 67 and older. MEASUREMENTS:Self-reported sleep...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2009.02490.x
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND:Elderly adults (65 years of age and older) are of particular concern for traumatic amputations due to age-related changes in vision and coordination, making them more susceptible to injury. OBJECTIVES:The objective of this study is to describe the epidemiology of traumatic amputations in the elderly adults ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.13889
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVES:Measurements of health-related quality of life (HRQL) are an essential component in overall assessment of health status, particularly in older patients. Nevertheless, how measures of HRQL relate to measures of disease severity is largely unexplored. This study was carried out to explore the relationship betw...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:
更新日期:2000-11-01 00:00:00
abstract:OBJECTIVE:To examine the relationship between gender and specific types of behavior problems that occur in patients with Alzheimer's disease. DESIGN:This was an observational study using the Dementia Behavior Disturbance Scale to quantify and define behavioral problems encountered by caregivers. Multiple regressions w...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1996.tb01447.x
更新日期:1996-05-01 00:00:00
abstract::Cardiovascular diseases and their treatment in the aged are discussed under the headings of ischemic heart disease, hypertension, cardiac failure (with special reference to the use of diuretics and digoxin), infective carditis and thyroid disorders. Advanced age modifies the approach to treatment; the choice of drugs ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/j.1532-5415.1975.tb00970.x
更新日期:1975-03-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Recently revised vaccination recommendations for US adults, aged 65 years and older, include both 23-valent pneumococcal polysaccharide vaccine (PPSV23) and 13-valent pneumococcal conjugate vaccine (PCV13), with PCV13 now recommended for immunocompetent older people based on shared decision making...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16373
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVES:To investigate the effectiveness of an exercise program in improving ability to perform activities of daily living (ADLs), physical performance, and nutritional status and decreasing behavioral disturbance and depression in patients with Alzheimer's disease (AD). DESIGN:Randomized, controlled trial. SETTIN...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1532-5415.2007.01035.x
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVES:To determine the relationship between prealbumin, nutrient intake, and indicators of inflammation for recuperative and rehabilitative care patients. DESIGN:Prospective cohort. SETTING:Recuperative Care Unit within a Veterans Administration Nursing Home Care Unit. PARTICIPANTS:One hundred eleven men (100 w...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2008.01789.x
更新日期:2008-07-01 00:00:00
abstract:OBJECTIVES:To determine whether women with sarcopenia and low bone mineral density (BMD) are at greater risk of clinical fractures than those with sarcopenia or low BMD alone. DESIGN:Women's Health Initiative (WHI) Observational and Clinical trials. SETTING:Three U.S. clinical centers (Pittsburgh, PA; Birmingham, AL;...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/jgs.15050
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:To identify specific characteristics of patients, physicians, and treatment settings associated with decreased receipt of essential medications in a chronically ill, older population following a Medicaid three-prescription monthly reimbursement limit (cap). DESIGN:Quasi-experiment with bivariate and multivar...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1046/j.1532-5415.2001.49158.x
更新日期:2001-06-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to determine the association between driving cessation and depressive symptoms among older drivers. Previous efforts in this area have focused on the factors associated with cessation, not the consequences of having stopped. DESIGN:Cohort study. SETTING:Urban community. PARTI...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1997.tb04508.x
更新日期:1997-02-01 00:00:00
abstract::Recurrent Clostridium difficile infection (CDI) is a common nosocomial infection that has a large effect on morbidity and quality of life in older adults in hospitals and long-term care facilities. Because antibiotics are often unsuccessful in curing this disease, fecal transplantation has emerged as a second-line the...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/jgs.12378
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVE:This study was conducted to determine the incidence of long bone fractures in institutionalized older persons and to describe preceding traumatic events and the functional status of individuals sustaining fractures. DESIGN:A 1-year, prospective, cumulative incidence survey. SETTING:Eleven skilled nursing ca...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1995.tb06381.x
更新日期:1995-02-01 00:00:00
abstract::Drug prescribing for ambulatory patients greater than or equal to 85 years of age was studied using data from the 1980 National Ambulatory Medical Care Survey (NAMCS) on office visits to physicians. NAMCS is a survey by the US National Center for Health Statistics, which collected information on office visits and extr...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1984.tb05855.x
更新日期:1984-02-01 00:00:00
abstract::The long-held belief that outcome data from intervention trials in men are generalizable to women has created the framework in which the primary prevention of coronary heart disease (CHD) in women is viewed, but over the past decade, data have accumulated to refute such a supposition of generalizability. These lines o...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/jgs.12140
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:To evaluate the physical ability and psychocognitive status of a population more than 90 years of age with regard to sociodemographic, behavioral, and biomedical variables known to affect functional status in old age. DESIGN:A survey design was used. SETTING:Emilia Romagna, Northern Italy. PARTICIPANTS:Eig...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1997.tb03769.x
更新日期:1997-10-01 00:00:00
abstract:OBJECTIVES:To analyze the relationship between serum total cholesterol (TC) and all-cause mortality, taking into account various potential confounders. DESIGN:Population-based prospective cohort study. SETTING:Older Italians residing in the general community. PARTICIPANTS:Four thousand five hundred twenty-one men an...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1046/j.1365-2389.2003.51313.x
更新日期:2003-07-01 00:00:00
abstract:OBJECTIVES:Patients undergoing hip fracture surgery have a 10 times increased risk of stroke compared with the general population. We aimed to evaluate the association between the CHA2 DS2 -VASc (congestive heart failure, hypertension, age ≥75 years, diabetes, previous stroke/TIA [transient ischemic attack]/systemic em...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16452
更新日期:2020-08-01 00:00:00