Extracorporeal removal of anticancer drugs in hepatic artery infusion: the effect of direct hemoperfusion combined with venovenous bypass.

abstract：:We investigated the effects of infusion of somatostatin (200 and 500 ng/kg/min) on central hemodynamics and renal blood flow measured with radioactive microspheres. At the lower dose infusion rate somatostatin did not alter any hemodynamic parameter, but at 500 ng/kg/min somatostatin caused minor transient bradycardia...

journal_title：Surgery

authors： Price BA,Jaffe BM,Zinner MJ

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:Despite curative resection of hepatocellular carcinoma, patients have a high probability of recurrence. We examined indications for liver resection in cases of recurrent hepatocellular carcinoma. METHODS:Patients undergoing a second liver resection (n=210) or treatment by transcatheter arterial chemoemboliz...

journal_title：Surgery

authors： Yagi R,Midorikawa Y,Moriguchi M,Nakayama H,Aramaki O,Yamazaki S,Higaki T,Takayama T

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Outcome for most abdominal wall defects is related to the presence or absence of additional anomalies or prematurity. In gastroschisis, outcome is almost as closely related to the severity of the inflammatory "peel" on bowel that is thought to result from direct contact with amniotic fluid. Improving eviscer...

journal_title：Surgery

authors： Coughlin JP,Drucker DE,Jewell MR,Evans MJ,Klein MD

更新日期：1993-10-01 00:00:00

abstract：:A retrospective study was performed on 65 patients with intractable angina and subtotal coronary occlusions undergoing aortocoronary artery bypass (ACB) to determine whether the local occlusion (L.O.) or the ischemic arrest (I.A.) technique was perferable in performing the distal coronary artery bypass. In 23 patients...

journal_title：Surgery

authors： Ellis RJ,Kligfield P,Gay W,Ebert PA

更新日期：1975-10-01 00:00:00

abstract：BACKGROUND:Although intracellular protease activation is thought to be an early event in acute pancreatitis, factors determining progression from edematous to necrotizing pancreatitis are largely unknown. With enterokinase as a probe and an immunoassay quantifying free trypsinogen activation peptides (TAP), we sought e...

journal_title：Surgery

authors： Fernández-del Castillo C,Schmidt J,Warshaw AL,Rattner DW

更新日期：1994-09-01 00:00:00

abstract：:Among 2411 consecutive arterial reconstructions performed with synthetic prosthetic material in Denmark during a 4-year period, 62 patients (2.6%) developed graft infection. Graft infection occurred only when the groin had been incised. The incidence of infection and the spread of infection along the graft did not rel...

journal_title：Surgery

authors： Lorentzen JE,Nielsen OM,Arendrup H,Kimose HH,Bille S,Andersen J,Jensen CH,Jacobsen F,Røder OC

更新日期：1985-07-01 00:00:00

abstract：BACKGROUND:Aggressive screening for blunt cerebrovascular injury (BCVI) and prompt anticoagulation for documented injuries has resulted in a significant reduction in ischemic neurologic events. An association between vertebral artery injuries (VAIs) and specific cervical spine fracture patterns has been suggested; howe...

journal_title：Surgery

authors： Cothren CC,Moore EE,Ray CE Jr,Johnson JL,Moore JB,Burch JM

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The number of dendritic cells (DC) in the local tumor environment correlates with patient survival in numerous tumors. The relationship of DC infiltration in the tumor microenvironment and prognosis was examined in patients with pancreatic adenocarcinoma. METHODS:Forty-seven pancreatectomy specimens with a ...

journal_title：Surgery

authors： Dallal RM,Christakos P,Lee K,Egawa S,Son YI,Lotze MT

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:This study was designed to compare the effects of hyperpolarizing versus depolarizing cardioplegic solutions on the coronary vasomotor regulation, specifically focusing on coronary myoplasmic Ca2+-myosin light chain (MLC) phosphorylation pathway and beta-adrenergic signal transduction. METHODS:With the use ...

journal_title：Surgery

authors： Matsuda N,Sellke FW

更新日期：2000-08-01 00:00:00

abstract：:Abdominal aortic reconstruction was successfully performed in three kidney transplant patients without the use of any specific measures to protect the kidney transplant during aortic cross-clamping. The cases are discussed in relation to previously published case reports describing various surgical techniques to prote...

journal_title：Surgery

authors： Jivegård L,Blohmé I,Holm J,Karlberg I

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Oxidative stress and inflammation are implicated in the pathogenesis of steatohepatitis. We hypothesize that Roux-en-Y gastric bypass reduces oxidative stress and inflammation in the liver of obese rats via activation of AMPK-α. METHODS:Obese Sprague-Dawley male rats underwent either sham operation or Roux-...

journal_title：Surgery

authors： Peng Y,Li JZ,You M,Murr MM

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Total parenteral nutrition is an etiologic factor in the formation of biliary sludge. We studied whether enteral nutrition is also a risk factor for sludge. METHODS:Fifty patients with a needle catheter jejunostomy (NCJ) placed during a major abdominal operation underwent preoperative and weekly postoperati...

journal_title：Surgery

authors： Schwesinger WH,Page CP,Strodel WE,Ghiatis AA,Chopra S,Gross GW,Sirinek KR

更新日期：1998-10-01 00:00:00

abstract：:Refractory esophageal variceal hemorrhage (EVH) remains a formidable problem in patients awaiting liver transplantations. Transjugular intrahepatic portosystemic shunts (TIPS) have provided an alternative approach for managing EVH that may obviate the need for portosystemic shunt surgery. Experience with TIPS placemen...

journal_title：Surgery

authors： Woodle ES,Darcy M,White HM,Perdrizet GA,Vesely TM,Picus D,Hicks M,So SK,Jendrisak MD,McCullough CS

更新日期：1993-03-01 00:00:00

abstract：:Plasma lipid and lipoprotein levels and composition of the very low-, low-, and high-density lipoproteins (VLDL, LDL, HDL) were studied in white New Zealand rabbits in the control state, 8 weeks after initiation of a 2% cholesterol-enriched diet, and sequentially for 16 weeks following a partial ileal bypass (PIB) pro...

journal_title：Surgery

authors： Sirtori CR,Ghiselli GC,Catapano AL,Lovati MR,Fragiacomo C,Fox U,Majone G,Buchwald H

更新日期：1981-02-01 00:00:00

abstract：BACKGROUND:This study examines factors associated with the performance of orthotopic liver transplantation (OLT) without red blood cell (RBC) transfusion. METHODS:Between January 1992 and December 1994, 306 primary OLTs were performed with recipients divided into two groups: group 1 patients (61 recipients, 20% of tot...

journal_title：Surgery

authors： Cacciarelli TV,Keeffe EB,Moore DH,Burns W,Chuljian P,Busque S,Concepcion W,So SK,Esquivel CO

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Hypoparathyroidism after cervical exploration is a rare but problematic complication. Cryopreservation and subsequent autotransplantation of parathyroid tissue are infrequently used to combat this problem; effective usage of this surgical adjunct remains variable. METHODS:From 1981 through 1995 we performed...

journal_title：Surgery

authors： Caccitolo JA,Farley DR,van Heerden JA,Grant CS,Thompson GB,Sterioff S

更新日期：1997-12-01 00:00:00

abstract：:We performed spirometry on 114 morbidly obese patients considered for gastric bypass surgery to assess its efficacy as a preoperative screening test. One hundred eight subjects underwent surgery, and 61 patients returned for repeat spirometry 1 year later. The average preoperative forced vital capacity (FVC), forced e...

journal_title：Surgery

authors： Crapo RO,Kelly TM,Elliott CG,Jones SB

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:Only annual mammography and physical examination are recommended for the post-treatment surveillance of early stage breast cancer. METHODS:We used Texas Cancer Registry-Medicare linked data (2001-2007) to identify physician visits and use of mammography, magnetic resonance imaging (MRI), computed tomography...

journal_title：Surgery

authors： Parmar AD,Sheffield KM,Vargas GM,Han Y,Chao C,Riall TS

更新日期：2013-08-01 00:00:00

abstract：:Cholecystectomy will not always relieve the abdominal symptoms of the patient with gallstones. The functional effects of gallbladder removal in a patient with a patent cystic duct are not known in detail. Studies of the function of the gallbladder and pancreas have suggested feedback mechanisms for the release of chol...

journal_title：Surgery

authors： Gelin J,Rehfeld JF,Jansson R,Svanvik J

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to clarify the relationships of extractable and secreted parathyroid hormone (PTH) and parathyroid secretory protein (PSP) in human parathyroid tumors to PTH messenger RNA (mRNA), PSP mRNA, and cell replication. METHODS AND RESULTS:In tissue cultures of seven adenomas and five ...

journal_title：Surgery

authors： Weber CJ,Russell J,Costanzo MK,Karp F,Benjamin M,Hardy MA,Feind CR

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:The purpose of this experimental study was to test whether transfusion potentiated physiologic changes associated with fluid resuscitated trauma in controlled conditions. METHODS:Anesthetized and ventilated mongrel pigs were subjected to soft-tissue injury plus 35% hemorrhage and 1 hour shock and then were ...

journal_title：Surgery

authors： Lyden SP,Patton JH Jr,Woodman GE,Ragsdale DN,Willis AP,Fabian TC,Proctor KG

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Polymorphonuclear neutrophil (PMN) sequestration in the lung is a hallmark of acute respiratory distress syndrome (ARDS). We have shown that 25% Albumin (A25) resuscitation attenuates lung injury after hemorrhagic shock and lipopolysaccharide (LPS) exposure by reducing lung leukosequestration. We hypothesize...

journal_title：Surgery

authors： Powers KA,Kapus A,Khadaroo RG,Papia G,Rotstein OD

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:We have demonstrated that gastrin-releasing peptide (GRP) binds specifically to its cell surface receptor, GRP-R, to act as an autocrine/paracrine growth factor for neuroblastomas (NBs); an increased expression of GRP-R was found in more advanced-stage NBs. Ets family proteins are nuclear targets for intrace...

journal_title：Surgery

authors： Qiao J,Cree J,Kang J,Kim S,Evers BM,Chung DH

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Liver cell proliferation after partial hepatectomy in rats has been thoroughly investigated. Although DNA synthesis and morphologic restoration have been studied in this rat model, the functional capacity of the remnant liver during regeneration has not been elucidated. METHODS:We measured the indocyanine g...

journal_title：Surgery

authors： Hashimoto M,Sanjo K

更新日期：1997-06-01 00:00:00

abstract：PURPOSE:Enhancer of zeste homologue 2 (EZH2), a component of the chromatin modification protein complex, is upregulated in pancreatic ductal adenocarcinoma (PDAC), whereas loss of p53 and its downstream target, p21(waf1/cip1), is also observed frequently. We sought to investigate the role of the p53-p21(waf1/cip1) path...

journal_title：Surgery

authors： Batchu RB,Qazi AM,Gruzdyn OV,Semaan A,Seward SM,Chamala S,Dhulipala VB,Bouwman DL,Weaver DW,Gruber SA

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Few studies discuss causes and outcomes of peritonitis in low-income settings. This study describes epidemiology of patients with peritonitis at a Rwandan referral hospital. Identification of risk factors associated with mortality and unplanned reoperation could improve management of peritonitis. METHODS:Da...

journal_title：Surgery

authors： Ndayizeye L,Ngarambe C,Smart B,Riviello R,Majyambere JP,Rickard J

更新日期：2016-12-01 00:00:00

abstract：:Several clinical studies have documented an increased incidence of gallstones after truncal vagotomy. Previous laboratory studies, however, have failed to establish a clear mechanism for this phenomenon. Whereas lithogenic bile is a prerequisite for cholesterol cholelithiasis, gallbladder stasis has also been shown to...

journal_title：Surgery

authors： Pitt HA,Doty JE,Roslyn JJ,DenBesten L

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:Hepatectomy for colorectal liver metastases (CRLM) may offer good long-term survival. The impact of the tumor-free surgical margin on long-term results remains controversial, and we have assessed this component in 185 patients. METHODS:Between 1992 and 2005, 185 patients underwent primary hepatectomy with c...

journal_title：Surgery

authors： Nuzzo G,Giuliante F,Ardito F,Vellone M,Giovannini I,Federico B,Vecchio FM

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Misdiagnosed primary hyperparathyroidism (PHPT) during thyroid surgery may lead to a difficult reoperation. Because PHPT is often asymptomatic, calcium measurements have been recommended before thyroid surgery, but no study has focused on the results of a prospective PHPT screening. METHODS:The prospective ...

journal_title：Surgery

authors： Denizot A,Dadoun F,Meyer-Dutour A,Alliot P,Argème M

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Endovascular approaches to aortoiliac disease are becoming increasingly frequent due to decreases in recovery time, bleeding, and discomfort. Despite this trend, little is known about the predictors of complications. This study was designed to identify risk factors for major 30-day morbidity and mortality af...

journal_title：Surgery

authors： Thomas AT,Leitman IM

更新日期：2018-08-01 00:00:00