Intrahepatic portosystemic vascular stents: a bridge to hepatic transplantation.

Abstract:

:Refractory esophageal variceal hemorrhage (EVH) remains a formidable problem in patients awaiting liver transplantations. Transjugular intrahepatic portosystemic shunts (TIPS) have provided an alternative approach for managing EVH that may obviate the need for portosystemic shunt surgery. Experience with TIPS placement and subsequent successful hepatic transplantation in patients without previous portosystemic shunt surgery has not been previously reported. Two patients are reported who underwent TIPS placement and subsequent successful hepatic transplantation without previous portosystemic shunt surgery. This experience indicates that (1) TIPS can provide effective control of EVH for at least several weeks, (2) TIPS placement decreases portal hypertension, thus facilitating technical performance of the transplant procedure and minimizing blood loss, (3) TIPS may undergo vascular incorporation, thus requiring that they be accurately positioned so that the lengths of suprahepatic inferior vena cava and portal vein are not compromised at the time of transplantation, (4) TIPS thrombosis can be effectively treated and prolonged patency may be observed, and (5) deterioration in hepatic function and exacerbation of hepatic encephalopathy were not observed after TIPS placement. In summary, TIPS provide an attractive, effective means for managing refractory EVH in patients awaiting liver transplantation.

journal_name

Surgery

journal_title

Surgery

authors

Woodle ES,Darcy M,White HM,Perdrizet GA,Vesely TM,Picus D,Hicks M,So SK,Jendrisak MD,McCullough CS

subject

Has Abstract,Author List Incomplete

pub_date

1993-03-01 00:00:00

pages

344-51

issue

3

eissn

0039-6060

issn

1532-7361

pii

0039-6060(93)90212-V

journal_volume

113

pub_type

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