Implications of Perioperative Polypharmacy in Adolescents Undergoing Bariatric Surgery: a Single-Center Experience.

Abstract:

:Adolescents seeking bariatric surgery may present with pre-existing psychiatric diagnoses for which they use chronic medications. To heighten awareness concerning perioperative polypharmacy in adolescents with extreme obesity, we conducted a retrospective review of patients undergoing laparoscopic sleeve gastrectomy between February 2010 and May 2017 at Children's National Health System (CNHS). A total of 167 adolescent patients had pre-existing psychiatric diagnoses which included depression (50%), anxiety (23%), ADHD (23%), and binge eating disorder (11%). Medications prescribed to treat these diagnoses included selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs). Additionally, all patients were given fentanyl, ondansetron, morphine, and acetaminophen perioperatively. Although no life threatening symptoms of drug-drug interactions (DDIs) were appreciated, the combined use of many different potent drugs in these patients warrants attention.

journal_name

Obes Surg

journal_title

Obesity surgery

authors

Williams EF,Vaughns JD,Mackey ER,Muret JC,Nadler EP,van den Anker JN

doi

10.1007/s11695-020-04456-w

subject

Has Abstract

pub_date

2020-07-01 00:00:00

pages

2832-2835

issue

7

eissn

0960-8923

issn

1708-0428

pii

10.1007/s11695-020-04456-w

journal_volume

30

pub_type

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